LOCUS AF048837 1991 bp mRNA linear HUM 21-JUN-1998
DEFINITION Homo sapiens cGMP-specific phosphodiesterase (PDE9A2) mRNA,
complete cds.
ACCESSION AF048837
VERSION AF048837.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1991)
AUTHORS Fisher,D.A., Smith,J.F., Pillar,J.S., St Denis,S.H. and Cheng,J.B.
TITLE Isolation and characterization of PDE9A, a novel human
cGMP-specific phosphodiesterase
JOURNAL J. Biol. Chem. 273 (25), 15559-15564 (1998)
PUBMED 9624146
REFERENCE 2 (bases 1 to 1991)
AUTHORS Fisher,D.A., Smith,J.F., Pillar,J.S., St. Denis,S.H. and Cheng,J.B.
TITLE Direct Submission
JOURNAL Submitted (17-FEB-1998) Molecular Science, Pfizer Central Research,
Eastern Point Road, Groton, CT 06340, USA
FEATURES Location/Qualifiers
source 1..1991
/db_xref="H-InvDB:HIT000064159"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1991
/gene="PDE9A2"
CDS 61..1842
/gene="PDE9A2"
/note="PDE9A"
/codon_start=1
/product="cGMP-specific phosphodiesterase"
/protein_id="AAC39778.1"
/translation="MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATG
LPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSA
ERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQV
AEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSR
TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLE
HMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQ
EKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQI
LAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHM
TLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVT
KATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKK
TDSLTSGATEKSRERSRDVKNSEGDCA"
BASE COUNT 538 a 530 c 544 g 379 t
ORIGIN
1 cgcggcggct ggcgtcggga aagtacagta aaaagtccga gtgcagccgc cgggcgcagg
61 atgggatccg gctcctccag ctaccggccc aaggccatct acctggacat cgatggacgc
121 attcagaagg taatcttcag caagtactgc aactccagcg acatcatgga cctgttctgc
181 atcgccaccg gcctgcctcg gaacacgacc atctccctgc tgaccaccga cgacgccatg
241 gtctccatcg accccaccat gcccgcgaat tcagaacgca ctccgtacaa agtgagacct
301 gtggccatca agcaactctc cgctggtgtc gaggacaaga gaaccacaag ccgtggccag
361 tctgctgaga gaccactgag ggacagacgg gttgtgggcc tggagcagcc ccggagggaa
421 ggagcatttg aaagtggaca ggtagagccc aggcccagag agccccaggg ctgctaccag
481 gaaggccagc gcatccctcc agagagagaa gaattaatcc agagcgtgct ggcgcaggtt
541 gcagagcagt tctcaagagc attcaaaatc aatgaactga aagctgaagt tgcaaatcac
601 ttggctgtcc tagagaaacg cgtggaattg gaaggactaa aagtggtgga gattgagaaa
661 tgcaagagtg acattaagaa gatgagggag gagctggcgg ccagaagcag caggaccaac
721 tgcccctgta agtacagttt tttggataac cacaagaagt tgactcctcg acgcgatgtt
781 cccacttacc ccaagtacct gctctctcca gagaccatcg aggccctgcg gaagccgacc
841 tttgacgtct ggctttggga gcccaatgag atgctgagct gcctggagca catgtaccac
901 gacctcgggc tggtcaggga cttcagcatc aaccctgtca ccctcaggag gtggctgttc
961 tgtgtccacg acaactacag aaacaacccc ttccacaact tccggcactg cttctgcgtg
1021 gcccagatga tgtacagcat ggtctggctc tgcagtctcc aggagaagtt ctcacaaacg
1081 gatatcctga tcctaatgac agcggccatc tgccacgatc tggaccatcc cggctacaac
1141 aacacgtacc agatcaatgc ccgcacagag ctggcggtcc gctacaatga catctcaccg
1201 ctggagaacc accactgcgc cgtggccttc cagatcctcg ccgagcctga gtgcaacatc
1261 ttctccaaca tcccacctga tgggttcaag cagatccgac agggaatgat cacattaatc
1321 ttggccactg acatggcaag acatgcagaa attatggatt ctttcaaaga gaaaatggag
1381 aattttgact acagcaacga ggagcacatg accctgctga agatgatttt gataaaatgc
1441 tgtgatatct ctaacgaggt ccgtccaatg gaagtcgcag agccttgggt ggactgttta
1501 ttagaggaat attttatgca gagcgaccgt gagaagtcag aaggccttcc tgtggcaccg
1561 ttcatggacc gagacaaagt gaccaaggcc acagcccaga ttgggttcat caagtttgtc
1621 ctgatcccaa tgtttgaaac agtgaccaag ctcttcccca tggttgagga gatcatgctg
1681 cagccacttt gggaatcccg agatcgctac gaggagctga agcggataga tgacgccatg
1741 aaagagttac agaagaagac tgacagcttg acgtctgggg ccaccgagaa gtccagagag
1801 agaagcagag atgtgaaaaa cagtgaagga gactgtgcct gaggaaagcg gggggcgtgg
1861 ctgcagttct ggacgggctg gccgagctgc gcgggatcct tgtgcaggga agagctgccc
1921 tgggcacctg gcaccacaag accatgtttt ctaagaacca ttttgttcac tgatacaaaa
1981 aaaaaaaaaa a
//