LOCUS AF047711 4368 bp mRNA linear HUM 14-JAN-1999
DEFINITION Homo sapiens nGAP mRNA, complete cds.
ACCESSION AF047711
VERSION AF047711.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4368)
AUTHORS Noto,S., Maeda,T., Hattori,S., Inazawa,J., Imamura,M., Asaka,M. and
Hatakeyama,M.
TITLE A novel human RasGAP-like gene that maps within the prostate cancer
susceptibility locus at chromosome 1q25
JOURNAL FEBS Lett. 441 (1), 127-131 (1998)
PUBMED 9877179
REFERENCE 2 (bases 1 to 4368)
AUTHORS Noto,S., Maeda,T., Hattori,S. and Hatakeyama,M.
TITLE Direct Submission
JOURNAL Submitted (11-FEB-1998) Department of Viral Oncology, The Cancer
Institute, Japanese Foundation for Cancer Research, 1-37-1
Kami-Ikebukuro, Toshima-ku, Tokyo, Japan
FEATURES Location/Qualifiers
source 1..4368
/db_xref="H-InvDB:HIT000064140"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q24"
CDS 126..3545
/note="ras GTPase activating protein"
/codon_start=1
/product="nGAP"
/protein_id="AAD04814.1"
/translation="MQTPEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFS
KRLKGSIKRTKSQSKLDRNTSFRLPSLRSTDDRSRGLPKLKESRSHESLLSPCSTVEC
LDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPN
KDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEF
FSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNK
GKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACA
LVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHD
ALGEFIKALYESDENCEVDPSKCSSSELIDHQSNLKMCCELAFCKIINSYCVFPRELK
EVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLT
LIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGY
IDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQ
QLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQ
QASSQSMTYSEKDERESSLPNGRSVSLMDLQDTHAAQVEHASVMLDVPIRLTGSQLSI
TQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGGLQPLSFQNPVYHLNNPIPAMPKA
SIDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTVPDRHIP
LALPRQNSTGQAQIRKVDQGGLGARAKAPPSLPHSASLRSTGSMSVVSAALVAEPVQN
GSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEED
VEETEQNLDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKA
RLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKR
IVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC"
BASE COUNT 1292 a 1022 c 1012 g 1042 t
ORIGIN
1 cgaaatgaga gcaaaaaggg agagagcagg aaagcgagca caggcgagta cagtatacaa
61 agtgttttga gtttctgact ggcgtgccgg aaagatcatg ttagcacacc cagaaactcc
121 acacgatgca gaccccagag gtaccagcag aaaggtcccc tcgtagacgg agtatctcag
181 ggaccagtac atcagagaaa cccaactcca tggacactgc aaatacctca cccttcaaag
241 taccaggatt cttcagcaag cgcctgaaag gctccatcaa gaggaccaaa agccagtcaa
301 agcttgacag aaacacgagc tttcggcttc catcccttcg cagtacagat gacaggtctc
361 gtgggctgcc taaactaaaa gagtcacgtt cccatgaatc cttgctgagc ccatgcagca
421 cagtggaatg tctggatctt ggtagagggg aacctgtatc agtgaaacca cttcatagta
481 gcatccttgg acaagacttc tgctttgagg ttacctactt aagtggaagt aaatgcttca
541 gctgtaattc tgcttctgag agagacaagt ggatggaaaa ccttcgcagg acagttcaac
601 ctaataagga caattgcagg cgagctgaaa atgttcttcg tttatggatc attgaagcca
661 aggaccttgc ccctaaaaag aaatatttct gcgaactgtg ccttgatgat accctctttg
721 ctcgtacaac cagcaagacc aaagcagaca atattttctg gggcgaacat tttgaattct
781 tcagccttcc acctcttcat agtatcacag ttcacattta caaggatgtg gaaaaaaaga
841 aaaaaaagga caagaataat tatgtagggc tagtcaacat ccccactgcc agtgtgactg
901 gtcgccaatt tgtagaaaag tggtatccag tgagtacacc tacacccaac aaaggaaaga
961 caggaggacc ttctattcgg attaaatcac gtttccaaac tatcaccatt ctgcctatgg
1021 agcaatacaa agaatttgca gaatttgtca ccagcaacta caccatgctg tgttctgtcc
1081 ttgagccagt aattagtgtg agaaataaag aggagttggc ttgtgcctta gtgcacattc
1141 ttcaaagtac tggcagagcc aaggattttc tgactgactt ggtgatgtct gaggtggatc
1201 gttgtggaga gcatgatgtc ttgatcttca gagagaacac tattgccacc aaatccattg
1261 aggaatacct caagttggtg ggacaacagt atcttcatga cgcactgggg gagtttatca
1321 aagctttgta tgagtccgat gagaactgtg aagtggatcc cagcaaatgt tcatctagtg
1381 aactgataga ccatcagagc aacctgaaaa tgtgctgtga gctggctttc tgcaagatca
1441 tcaactctta ctgtgttttc cctcgtgagt tgaaagaagt gtttgcatca tggaagcagc
1501 agtgcctgaa ccgtggcaag caagacatca gcgagaggct catcagtgcc tcattatttc
1561 tccgttttct gtgtccagcc attatgtctc ccagtctttt caaccttatg caggagtatc
1621 ctgatgaccg cacatctcgg actctaactc ttattgccaa ggtcattcag aacctggcca
1681 actttgccaa gtttggtaac aaagaggaat acatggcatt catgaatgat tttttagaac
1741 atgaatgggg tggaatgaag cgctttcttt tggagatctc taatccagac accatctcaa
1801 acaccccagg ctttgatggt tacattgatc tgggccgaga gctttcagtt ttgcattcct
1861 tactgtggga agtagtttcc caacttgata agggtgaaaa ttccttccta caggcgaccg
1921 tggcaaaatt ggggcctctc cctcgtgttc ttgctgatat taccaagtca ttgactaatc
1981 ctacgccaat acaacagcaa ctgagacgct tcactgaaca taactccagt ccaaatgtca
2041 gtggaagcct ctcctctggg ctgcagaaaa tatttgaaga ccccactgac agtgatttgc
2101 ataaactaaa atctccaagc caggacaaca cagacagcta cttcagaggg aaaacattat
2161 tgctggttca gcaagcctcc tctcagagca tgacttattc tgaaaaggat gaaagggaaa
2221 gtagccttcc taatggtcgg agcgtctccc tcatggacct ccaggacact catgctgctc
2281 aagtggagca tgcatctgtc atgcttgatg tgcctatacg cttgaccgga agccagcttt
2341 ccataaccca ggtggccagc atcaaacagc tgcgggaaac ccagagcact ccccaaagtg
2401 caccccaagt gagaaggccc ctgcacccag ccttgaacca gccaggtggc cttcagccct
2461 tgtcgttcca gaaccctgtc tatcacctca ataacccaat tccagcaatg ccaaaggcct
2521 ctatagattc cagtttggag aacctaagca ctgccagttc cagaagccaa agtaacagtg
2581 aagacttcaa gctcagtgga cccagcaata gcagcatgga agatttcact aaacgtagca
2641 ctcagagtga ggacttctcc aggcggcaca cggtgccaga tagacacata cctcttgctt
2701 tgccacgaca aaatagtact gggcaggccc agatccgaaa agtggaccag ggtgggttag
2761 gtgcccgagc caaagcccca ccatccctgc cacacagtgc ttctttacgt agcaccggga
2821 gcatgtcagt ggtgtccgca gccctggtgg ccgaacctgt gcagaatggg agccggtccc
2881 ggcagcagtc ctcttcctcc agagagagcc ctgttcccaa agttagagca atccagagac
2941 aacagacaca gcaggttcag tcacctgtgg actctgccac aatgtcccca gtagagagga
3001 cagcagcctg ggttctgaac aatgggcagt atgaagagga tgtggaagaa actgagcaaa
3061 atctagatga agccaagcat gctgagaagt atgaacaaga aattactaaa ctgaaggagc
3121 gcctgagagt ttccagccgg cgactggagg aatatgaacg ccgcttgctg gtgcaggagc
3181 agcagatgca gaagctgctg ctggaataca aggcccgact ggaggacagc gaggagcggc
3241 tccgaagaca gcaggaagaa aaagatagcc agatgaaaag catcatcagc aggctaatgg
3301 ctgtggaaga ggaactgaag aaggatcatg ctgagatgca agcagttatt gatgcaaagc
3361 agaaaataat tgatgcacag gaaaaacgga tcgtgtccct ggattcagcc aacaccagac
3421 tgatgagcgc gctgacccaa gtgaaggagc ggtacagcat gcaggtccgc aatggcatct
3481 cccccaccaa ccccaccaag ctttccatca cggagaatgg tgaattcaaa aacagcagct
3541 gctgacgggc tttgtctgtg gaaggagaca gaaggaaatt gacccactct cctatctcca
3601 gacctttacc tagcccctcc aggtttacag aatgttgcta cttcacaatg gcgatgtggt
3661 gagaaactcc tgaatgaaga aaggaacctt gtctttcagg gcataaggcg gcgacttcca
3721 aggtcaatgc ttttccccca catctctatg tacataggga acttagttct gggccatgta
3781 cagaaaatat cactgtaata taccaaaagg aagttaataa tgtagattac ctttttgatt
3841 attgctattt ttattattgt tttcctcttg ttgaaagcac tgcagttgtt acaggaagta
3901 aagtaggaat gttgtgtgag cgagacatga gcctgtagtt cagtaggtag agaccaagca
3961 tctatctgat agaacacatg gagtgcaata ggacattgtg agaaggattt ttcagggatt
4021 catctactag tttaaaaacc ccactctggc cctcttgtcc tttcagaaaa catgcaaata
4081 ccaagatcca tacaaaacaa taatttattc cactgatcaa ccaagactgg ttctggttgg
4141 acagctaatc tgatttgggg attcactgtt tcagaggaca cagacaaaag ctgttgcatc
4201 aaaactggac tttaggagta atttctattg aactcctgtc aatatgttta tttcctctgt
4261 ctacagcaga tgggagtctt ctcttttaga caggggcttt ttgtttttaa ccccaattgt
4321 aataaagggt gttctttttc ctctttagaa aaaaaaaaaa aaaaaaaa
//