LOCUS AF046025 2119 bp mRNA linear HUM 12-APR-1999
DEFINITION Homo sapiens activation of Sentrin/SUMO protein AOS1 (AOS1) mRNA,
complete cds.
ACCESSION AF046025
VERSION AF046025.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2119)
AUTHORS Gong,L., Li,B., Millas,S. and Yeh,E.T.
TITLE Molecular cloning and characterization of human AOS1 and UBA2,
components of the sentrin-activating enzyme complex
JOURNAL FEBS Lett. 448 (1), 185-189 (1999)
PUBMED 10217437
REFERENCE 2 (bases 1 to 2119)
AUTHORS Gong,L. and Yeh,E.T.H.
TITLE Direct Submission
JOURNAL Submitted (05-FEB-1998) Institute of Molecular Medicine, The
University of Texas Houston Health Science Center, 2121 W. Holcombe
Blvd., Suite 900, Houston, TX 77030, USA
REFERENCE 3 (bases 1 to 2119)
AUTHORS Gong,L. and Yeh,E.T.H.
TITLE Direct Submission
JOURNAL Submitted (12-APR-1999) Institute of Molecular Medicine, The
University of Texas Houston Health Science Center, 2121 W. Holcombe
Blvd., Suite 900, Houston, TX 77030, USA
REMARK Sequence update by submitter
COMMENT On Apr 12, 1999 this sequence version replaced AF046025.1.
FEATURES Location/Qualifiers
source 1..2119
/db_xref="H-InvDB:HIT000064009"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="placenta"
gene 1..2119
/gene="AOS1"
CDS 46..1086
/gene="AOS1"
/note="yeast AOS1 homolog; component of the activating
enzyme complex of the sentrinization pathway"
/codon_start=1
/product="activation of Sentrin/SUMO protein AOS1"
/protein_id="AAD23902.2"
/translation="MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGL
KGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNL
NPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFG
YHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKE
ALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDV
LDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM
KGNGIVECLGPK"
BASE COUNT 504 a 490 c 589 g 536 t
ORIGIN
1 ttggcttgag cgggaccgga gcttgaggca ggaagagccg gcgccatggt ggagaaggag
61 gaggctggcg gcggcattag cgaggaggag gcggcacagt atgaccggca gatccgcctg
121 tggggactgg aggcccagaa acggctgcgg gcctctcggg tgcttcttgt cggcttgaaa
181 ggacttgggg ctgaaattgc caagaatctc atcttggcag gagtgaaagg actgaccatg
241 ctggatcacg aacaggtaac tccagaagat cccggagctc agttcttgat tcgtactggg
301 tctgttggcc gaaatagggc tgaagcctct ttggagcgag ctcagaatct caaccccatg
361 gtggatgtga aggtggacac tgaggatata gagaagaaac cagagtcatt tttcactcaa
421 ttcgatgctg tgtgtctgac ttgctgctcc agggatgtca tagttaaagt tgaccagatc
481 tgtcacaaaa atagcatcaa gttctttaca ggagatgttt ttggctacca tggatacaca
541 tttgccaatc taggagagca tgagtttgta gaggagaaaa ctaaagttgc caaagttagc
601 caaggagtag aagatgggcc cgacaccaag agagcaaaac ttgattcttc tgagacaacg
661 atggtcaaaa agaaggtggt cttctgccct gttaaagaag ccctggaggt ggactggagc
721 agtgagaaag caaaggctgc tctgaagcgc acgacctccg actactttct ccttcaagtg
781 ctcttaaagt tccgtacaga taaaggaaga gatcccagtt ctgatacata tgaggaagat
841 tctgagttgt tgctccagat acgaaatgat gtgcttgact cactgggtat tagtcctgac
901 ctgcttcctg aggactttgt caggtactgc ttctccgaga tggccccagt gtgtgcggtg
961 gttggaggga ttttggcaca ggaaattgtg aaggccctgt ctcagcggga ccctcctcac
1021 aacaacttct tcttcttcga tggcatgaag gggaatggga ttgtggagtg ccttggcccc
1081 aagtgaactc aagatttggc agccccagag atgccaactg cagcatgccc acctgtattc
1141 cctgtcccct tccttcatga aggcatctcc aggcaaggaa aactgaagtc attggcccga
1201 tacaaaacat ttcctgcaac gaaggaggtg gtgccgacgt gctgcttccc atcaccagca
1261 gctgctcgac aaggggcgca gggtggctgt ctttgttcca gcactgttca ggctgcctgt
1321 catcccgggc ctgccagctc ccctgagtga tgagcacttc caagcacccc tctgcccttt
1381 ctctgtcctt atgctgtccc ggcctcgcag ccctctgggg aattgtggga gatgcctgcc
1441 aggaatgagc aagctctgtt gctcgggagc ctcttgtaac cttcttggac ttattcccca
1501 cctgatacct tatagagaaa agtgtgaatt caggtggaga gtaggcccag gcccatgagg
1561 caccagtgga agcacagctc caagttcaga caggtgccct tagagaggaa aaccatgaca
1621 ggcaaatgca tttcctctgg agtttgagac cctgacaaac aacaggtggc atcctggtgt
1681 gctgttcttg agttttcgtt taggattagt tgagttccag ctgggttttg ggagaaagga
1741 gatgctacca agtctttgga tgttaagggc cgagacccct gcaaagttga gtattagaga
1801 gcttgtcttt caaggccagg ttccctgggg cttcaagggc taggagggag gagcctgccc
1861 cttttaacag aacccccagt tacatgcggc tcaagtcact cagaggctgt tgcatttcag
1921 ggctatgttg gtcctttgtt tacctcctaa accacagctg tttgtgtttc acatatgttg
1981 tgaattttcc ttggttcttt ttaaaggaat gataataaag ttacttgctt taggatttgc
2041 ttgtttttct tccacttcag aagcttctga gagggaatgg gatgatccta ccagttgcct
2101 tttcagacct gaggctcta
//