LOCUS AF044195 4803 bp mRNA linear HUM 15-OCT-1998
DEFINITION Homo sapiens IkappaB kinase complex associated protein (IKAP) mRNA,
complete cds.
ACCESSION AF044195
VERSION AF044195.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4803)
AUTHORS Cohen,L., Henzel,W.J. and Baeuerle,P.A.
TITLE IKAP is a scaffold protein of the IkappaB kinase complex
JOURNAL Nature 395 (6699), 292-296 (1998)
PUBMED 9751059
REFERENCE 2 (bases 1 to 4803)
AUTHORS Cohen,L. and Baeuerle,P.A.
TITLE Direct Submission
JOURNAL Submitted (22-JAN-1998) Screening, TULARIK, INC., 2, Corporate
Drive, South San Francisco, CA 94080, USA
FEATURES Location/Qualifiers
source 1..4803
/db_xref="H-InvDB:HIT000063942_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9q34"
gene 1..4803
/gene="IKAP"
CDS 304..4302
/gene="IKAP"
/codon_start=1
/product="IkappaB kinase complex associated protein"
/protein_id="AAC64258.1"
/translation="MRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEV
DPVSREVKNEVSLVAEGFLPEDGSGRIVGVQDLLDQESVCVATASGDVILCSLSTQQL
ECVGSVASGISVMSWSPDQELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFIT
VGWGRKETQFHGSEGRQAAFQMQMHESALPWDDHRPQVTWRGDGQFFAVSVVCPETGA
RKVRVWNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDKPNQQDIVFFEKNGLLHG
HFTLPFLKDEVKVNDLLWNADSSVLAVRLEDLQREKSSIPKTCVQLWTVGNYHWYLKQ
SLSFSTCGKSKIVSLMWDPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVA
VIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLAHPQKSNDLAVLDASNQISV
YKCGDCPSADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFENNEDQDVNPLKLGLLTW
IEEDVFLAVSHSEFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIISLCCNSKT
KSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFPVRFPYPCTQTELAMIGEEECVLGL
TDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSSNHV
SHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFKE
AFECMRKLRINLNPIYDHNPKVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMYP
APVTSSVYLSRDPDGNKIDLVCDAMRAVMESINPHKYCLSILTSHVKKTTPELEIVLQ
KVHELQGNAPSDPDAVSAEEALKYLLHLVDVNELYDHSLGTYDFDLVLMVAEKSQKDP
KEYLPFLNTLKKMETNYQRFTIDKYLKRYEKAIGHLSKCGPEYFPECLNLIKDKNLYN
EALKLYSPSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAHEKALSAFLTCGNWKQ
ALCVAAQLNFTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAVLLLLEGAA
WEEALRLVYKYNRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLVVRELKE
QAQQAGLDDEVPHGQESDLFSETSSVVSGSEMSGKYSHSNSRISARSSKNRRKAERKK
HSLKEGSPLEDLALLEALSEVVQNTENLKDEVYHILKVLFLFEFDEQGRELQKAFEDT
LQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKI
NRRTQWKLSLLD"
BASE COUNT 1325 a 1015 c 1192 g 1271 t
ORIGIN
1 gcggctgcct agttgacgca cccattgagt cgctggcttc tttgcagcgc ttcagcgttt
61 tcccctggag ggcgcctcca tccttggagg cctagtgccg tcggagaaga gagcgggagc
121 cgcggacaga gacgcgtgcg caattcggag ccgactctgg gtgcggactg tgggagctga
181 ctctgggtag ccggctgcgc gtggctgggg aggcgaggcc ggacgcacct ctgtttgggg
241 gtcctcagag attaatgatt catcaaggga tagttgtact gttctcgtgg gaatcacttc
301 atcatgcgaa atctgaaatt atttcggacc ctggagttca gggatattca aggtccaggg
361 aatcctcagt gcttctctct ccgaactgaa caggggacgg tgctcattgg ttcagaacat
421 ggcctgatag aagtagaccc tgtctcaaga gaagtgaaaa atgaagtttc tttggtggca
481 gaaggctttc ttccagagga tggaagtggc cgcattgttg gtgttcagga cttgctggat
541 caggagtctg tgtgtgtggc cacagcctct ggagacgtca tactctgcag tctcagcaca
601 caacagctgg agtgtgttgg gagtgtagcc agtggtatct ctgttatgag ttggagtcct
661 gaccaagagc tggtgcttct tgccacaggt caacagaccc tgattatgat gacaaaagat
721 tttgagccaa tcctggagca gcagatccat caggatgatt ttggtgaaag caagtttatc
781 actgttggat ggggtaggaa ggagacacag ttccatggat cagaaggcag acaagcagct
841 tttcagatgc aaatgcatga gtctgctttg ccctgggatg accatagacc acaagttacc
901 tggcgggggg atggacagtt ttttgctgtg agtgttgttt gcccagaaac aggggctcgg
961 aaggtcagag tgtggaaccg agagtttgct ttgcagtcaa ccagtgagcc tgtggcagga
1021 ctgggaccag ccctggcttg gaaaccctca ggcagtttga ttgcatctac acaagataaa
1081 cccaaccagc aggatattgt gttttttgag aaaaatggac tccttcatgg acactttaca
1141 cttcccttcc ttaaagatga ggttaaggta aatgacttgc tctggaatgc agattcctct
1201 gtgcttgcag tccggctgga agaccttcag agagaaaaaa gctccattcc gaaaacctgt
1261 gttcagctct ggactgttgg aaactatcac tggtatctca agcaaagttt atccttcagc
1321 acctgtggga agagcaagat tgtgtctctg atgtgggacc ctgtgacccc ataccggctg
1381 catgttctct gtcagggctg gcattacctc gcctatgatt ggcactggac gactgaccgg
1441 agcgtgggag ataattcaag tgacttgtcc aatgtggctg tcattgatgg aaacagggtg
1501 ttggtgacag tcttccggca gactgtggtt ccgcctccca tgtgcaccta ccaactgctg
1561 ttcccacacc ctgtgaatca agtcacattc ttagcacacc ctcaaaagag taatgacctt
1621 gctgttctag atgccagtaa ccagatttct gtttataaat gtggtgattg tccaagtgct
1681 gaccctacag tgaaactggg agctgtgggt ggaagtggat ttaaagtttg ccttagaact
1741 cctcatttgg aaaagagata caaaatccag tttgagaata atgaagatca agatgtaaac
1801 ccgctgaaac taggccttct cacttggatt gaagaagacg tcttcctggc tgtaagccac
1861 agtgagttca gcccccggtc tgtcattcac catttgactg cagcttcttc tgagatggat
1921 gaagagcatg gacagctcaa tgtcagttca tctgcagcgg tggatggggt cataatcagt
1981 ctatgttgca attccaagac caagtcagta gtattacagc tggctgatgg ccagatattt
2041 aagtaccttt gggagtcacc ttctctggct attaaaccat ggaagaactc tggtggattt
2101 cctgttcggt ttccttatcc atgcacccag accgaattgg ccatgattgg agaagaggaa
2161 tgtgtccttg gtctgactga caggtgtcgc tttttcatca atgacattga ggttgcgtca
2221 aatatcacgt catttgcagt atatgatgag tttttattgt tgacaaccca ttcccatacc
2281 tgccagtgtt tttgcctgag ggatgcttca tttaaaacat tacaggccgg cctgagcagc
2341 aatcatgtgt cccatgggga agttctgcgg aaagtggaga ggggttcacg gattgtcact
2401 gttgtgcccc aggacacaaa gcttgtatta cagatgccaa ggggaaactt agaagttgtt
2461 catcatcgag ccctggtttt agctcagatt cggaagtggt tggacaaact tatgtttaaa
2521 gaggcatttg aatgcatgag aaagctgaga atcaatctca atccgattta tgatcataac
2581 cctaaggtgt ttcttggaaa tgtggaaacc ttcattaaac agatagattc tgtgaatcat
2641 attaacttgt tttttacaga attgaaagaa gaagatgtca cgaagaccat gtaccctgca
2701 ccagttacca gcagtgtcta cctgtccagg gatcctgacg ggaataaaat agaccttgtc
2761 tgcgatgcta tgagagcagt catggagagc ataaatcctc ataaatactg cctatccata
2821 cttacatctc atgtaaagaa gacaacccca gaactggaaa ttgtactgca aaaagtacac
2881 gagcttcaag gaaatgctcc ctctgatcct gatgctgtga gtgctgaaga ggccttgaaa
2941 tatttgctgc atctggtaga tgttaatgaa ttatatgatc attctcttgg cacctatgac
3001 tttgatttgg tcctcatggt agctgagaag tcacagaagg atcccaaaga atatcttcca
3061 tttcttaata cacttaagaa aatggaaact aattatcagc ggtttactat agacaaatac
3121 ttgaaacgat atgaaaaagc cattggccac ctcagcaaat gtggacctga gtacttccca
3181 gaatgcttaa acttgataaa agataaaaac ttgtataacg aagctctgaa gttatattca
3241 ccaagctcac aacagtacca ggatatcagc attgcttatg gggagcacct gatgcaggag
3301 cacatgtatg agccagcggg gctcatgttt gcccgttgcg gtgcccacga gaaagctctc
3361 tcagcctttc tcacatgtgg caactggaag caagccctct gtgtggcagc ccagcttaac
3421 tttaccaaag accagctggt gggcctcggc agaactctgg caggaaagct ggttgagcag
3481 aggaagcaca ttgatgcggc catggttttg gaagagtgtg cccaggatta tgaagaagct
3541 gtgctcttgc tgttagaagg agctgcctgg gaagaagctt tgaggctggt atacaaatat
3601 aacagactgg atattataga aaccaacgta aagccttcca ttttagaagc ccagaaaaat
3661 tatatggcat ttctggactc tcagacagcc acattcagtc gccacaagaa acgtttattg
3721 gtagttcgag agctcaagga gcaagcccag caggcaggtc tggatgatga ggtaccccac
3781 gggcaagagt cagacctctt ctctgaaact agcagtgtcg tgagtggcag tgagatgagt
3841 ggcaaatact cccatagtaa ctccaggata tcagcgagat catccaagaa tcgccgaaaa
3901 gcggagcgga agaagcacag cctcaaagaa ggcagtccgc tggaggacct ggccctcctg
3961 gaggcactga gtgaagtggt gcagaacact gaaaacctga aagatgaagt ataccatatt
4021 ttaaaggtac tctttctctt tgagtttgat gaacaaggaa gggaattaca gaaggccttt
4081 gaagatacgc tgcagttgat ggaaaggtca cttccagaaa tttggactct tacttaccag
4141 cagaattcag ctaccccggt tctaggtccc aattctactg caaatagtat catggcatct
4201 tatcagcaac agaagacttc ggttcctgtt cttgatgctg agctttttat accaccaaag
4261 atcaacagaa gaacccagtg gaagctgagc ctgctagact gagtgactgc agttaggagg
4321 gatccgacag agaagaccat ttccactcat tcctgttgtc ctaccacccc ttgctctttg
4381 agggctggct attgagaact ggaaagagta aaatgataac ttaccttagc attgccaaga
4441 acttcagcag acaacaagca attctattta ttttatgttg tgtatacatc ttgatcatta
4501 gcaagacatt aagctttaac cattatggca ccattttgtg agaatgattg ttctttcact
4561 tgggctgttt gagagcataa ttatggtaat catgagatta atgtttcatg atttctacct
4621 ccaaagtgtg aagacaagta aaacaatgtt tctaaattgt cttattttgt tggcggagaa
4681 gattacaatg gctattagtg ctacatttgg tcaaatgtaa tcacttaaat agcttcttgt
4741 caccttaaac taaagcagaa taaaaagtat cctttgaaat taaaaaaaac aaaaaagcta
4801 aaa
//