LOCUS AF042380 1482 bp mRNA linear HUM 06-MAY-1999
DEFINITION Homo sapiens Grf40 adaptor protein (Grf40) mRNA, complete cds.
ACCESSION AF042380
VERSION AF042380.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1482)
AUTHORS Asada,H., Ishii,N., Sasaki,Y., Endo,K., Kasai,H., Tanaka,N.,
Takeshita,T., Tsuchiya,S., Konno,T. and Sugamura,K.
TITLE Grf40, A novel Grb2 family member, is involved in T cell signaling
through interaction with SLP-76 and LAT
JOURNAL J. Exp. Med. 189 (9), 1383-1390 (1999)
PUBMED 10224278
REFERENCE 2 (bases 1 to 1482)
AUTHORS Asada,H., Arita,T. and Sugamura,K.
TITLE Direct Submission
JOURNAL Submitted (10-JAN-1998) Microbiology & Immunology, Tohoku
University School of Medicine, 2-1 Seiryo-machi Aoba-ku, Sendai
980-8575, Japan
FEATURES Location/Qualifiers
source 1..1482
/db_xref="H-InvDB:HIT000063695"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="PHA-stimulated PBL"
gene 1..1482
/gene="Grf40"
CDS 193..1185
/gene="Grf40"
/note="SH3-SH2-SH3 adaptor molecule"
/codon_start=1
/product="Grf40 adaptor protein"
/protein_id="AAC69273.1"
/translation="MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEG
YVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDV
QHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSL
DRRSQGGPHLSGAVGEEIRPSMNRKLSDHPPTLPLQQHQHQPQPPQYAPAPQQLQQPP
QQRYLQHHHFHQERRGGSLDINDGHCGTGLGSEMNAALMHRRHTDPVQLQAAGRVRWA
RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMTR"
BASE COUNT 386 a 382 c 397 g 317 t
ORIGIN
1 tggatctgta aacttgcacc ctctttcaga gtggtacatg gaagacagca caaagtggat
61 ccatactctg aaatgcagta actctgatgc ttgaatttgt ctcccttctt gccagaaagg
121 attctaataa ctcggtgtca aagccaagac ataaactcaa ccccttctct tccaaaagct
181 tcacgttaca gcatggaagc tgttgccaag tttgatttca ctgcttcagg tgaggatgaa
241 ctgagctttc acactggaga tgttttgaag attttaagta accaagagga gtggtttaag
301 gcggagcttg ggagccagga aggatatgtg cccaagaatt tcatagacat ccagtttccc
361 aaatggtttc acgaaggcct ctctcgacac caggcagaga acttactcat gggcaaggag
421 gttggcttct tcatcatccg ggccagccag agctccccag gggacttctc catctctgtc
481 aggcatgagg atgacgttca acacttcaag gtcatgcgag acaacaaggg taattacttt
541 ctgtggactg agaagtttcc atccctaaat aagctggtag actactacag gacaaattcc
601 atctccagac agaagcagat cttccttaga gacagaaccc gagaagacca gggtcaccgg
661 ggcaacagcc tggaccggag gtcccaggga ggcccacacc tcagtggggc tgtgggagaa
721 gaaatccgac cttcgatgaa ccggaagctg tcggatcacc ccccgaccct tcccctgcag
781 cagcaccagc accagccaca gcctccgcaa tatgccccag cgccccagca gctgcagcag
841 cccccacagc agcgatatct gcagcaccac catttccacc aggaacgccg aggaggcagc
901 cttgacataa atgatgggca ttgtggcacc ggcttgggca gtgaaatgaa tgcggccctc
961 atgcatcgga gacacacaga cccagtgcag ctccaggcgg cagggcgagt gcggtgggcc
1021 cgggcgctgt atgactttga ggccctggag gatgacgagc tggggttcca cagcggggag
1081 gtggtggagg tcctggatag ctccaaccca tcctggtgga ccggccgcct gcacaacaag
1141 ctgggcctct tccctgccaa ctacgtggca cccatgaccc gataaactct tcaggggaca
1201 gaagcttttt gtctggagct gcccacaaga aagagggcaa ggaaaaaagg ctggactcca
1261 tgactatata tacatacatc tatctacatc tgcctgtgta cacacacaac tttttatact
1321 agtaatttat tggcaattgg gctggtaatt agttgatgca aaagggaact caggtggaga
1381 ataatattga cacttgcttt tctgcccccc tcaggggtgt gtggaaggca gtgggggagt
1441 tgggaggggg gcagggaaat gaaatggagt tttgtcctgg ca
//