LOCUS AF042282 2921 bp mRNA linear HUM 19-AUG-1998
DEFINITION Homo sapiens Hex1 (HEX1) mRNA, complete cds.
ACCESSION AF042282
VERSION AF042282.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2921)
AUTHORS Wilson,D.M. III, Carney,J.P., Coleman,M.A., Adamson,A.W.,
Christensen,M. and Lamerdin,J.E.
TITLE Hex1: a new human Rad2 nuclease family member with homology to
yeast exonuclease 1
JOURNAL Nucleic Acids Res. 26 (16), 3762-3768 (1998)
PUBMED 9685493
REFERENCE 2 (bases 1 to 2921)
AUTHORS Wilson,D.M. III, Carney,J.P., Coleman,M.A., Adamson,A.W.,
Christensen,M. and Lamerdin,J.E.
TITLE Direct Submission
JOURNAL Submitted (10-JAN-1998) Biology and Biotechnology Research Program,
Lawrence Livermore National Laboratory, 7000 East Ave, B361,
Livermore, CA 94550, USA
FEATURES Location/Qualifiers
source 1..2921
/db_xref="H-InvDB:HIT000063684"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE 843301"
/cell_line="HeLa S3"
/clone_lib="Stratagene Library Cat number 937216"
gene 1..2921
/gene="HEX1"
CDS 219..2630
/gene="HEX1"
/function="mismatch repair or recombination protein"
/note="putative 5'-3' exonuclease; similar to Drosophila
melanogaster Tosca protein encoded by GenBank Accession
Number X89022, Schizosaccharomyces pombe ExoI presented in
SwissProt Accession Number P53695 and Saccharomyces
cerevisiae ExoI presented in SwissProt Accession Number
P39875"
/codon_start=1
/product="Hex1"
/protein_id="AAC32259.1"
/translation="MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAE
KLAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLK
GKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNK
AGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYM
CILSGCDYLSSLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFI
RANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINT
FEQIDDYNPDTAMPAHSRSRSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKE
NPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGN
KSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFC
SSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNN
HIPGDHIPDKATVFTDEESYSFKSSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSP
SPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEF
SLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPG
LYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHNAENKPGLQIKLNELWKNF
GFKKF"
BASE COUNT 947 a 573 c 636 g 765 t
ORIGIN
1 gcacgaggtg ccacatgcga tctctgagat atgtacacag tcattcttac tatcgcactc
61 agccattctt actacgctaa agaagaaata attattcgag gatatttgcc tggcccagaa
121 gaaacttatg taaatttcat gaactattat atccgttttc ctcggagtga gagaaaactc
181 tttttagata tcatctgaga ggtagttaat ttggcaccat ggggatacag ggattgctac
241 aatttatcaa agaagcttca gaacccatcc atgtgaggaa gtataaaggg caggtagtag
301 ctgtggatac atattgctgg cttcacaaag gagctattgc ttgtgctgaa aaactagcca
361 aaggtgaacc tactgatagg tatgtaggat tttgtatgaa atttgtaaat atgttactat
421 ctcatgggat caagcctatt ctcgtatttg atggatgtac tttaccttct aaaaaggaag
481 tagagagatc tagaagagaa agacgacaag ccaatcttct taagggaaag caacttcttc
541 gtgaggggaa agtctcggaa gctcgagagt gtttcacccg gtctatcaat atcacacatg
601 ccatggccca caaagtaatt aaagctgccc ggtctcaggg ggtagattgc ctcgtggctc
661 cctatgaagc tgatgcgcag ttggcctatc ttaacaaagc gggaattgtg caagccataa
721 ttacagagga ctcggatctc ctagcttttg gctgtaaaaa ggtaatttta aagatggacc
781 agtttggaaa tggacttgaa attgatcaag ctcggctagg aatgtgcaga cagcttgggg
841 atgtattcac ggaagagaag tttcgttaca tgtgtattct ttcaggttgt gactacctgt
901 catcactgcg tgggattgga ttagcaaagg catgcaaagt cctaagacta gccaataatc
961 cagatatagt aaaggttatc aagaaaattg gacattatct caagatgaat atcacggtac
1021 cagaggatta catcaacggg tttattcggg ccaacaatac cttcctctat cagctagttt
1081 ttgatcccat caaaaggaaa cttattcctc tgaacgccta tgaagatgat gttgatcctg
1141 aaacactaag ctacgctggg caatatgttg atgattccat agctcttcaa atagcacttg
1201 gaaataaaga tataaatact tttgaacaga tcgatgacta caatccagac actgctatgc
1261 ctgcccattc aagaagtcgt agttgggatg acaaaacatg tcaaaagtca gctaatgtta
1321 gcagcatttg gcataggaat tactctccca gaccagagtc gggtactgtt tcagatgccc
1381 cacaattgaa ggaaaatcca agtactgtgg gagtggaacg agtgattagt actaaagggt
1441 taaatctccc aaggaaatca tccattgtga aaagaccaag aagtgcagag ctgtcagaag
1501 atgacctgtt gagtcagtat tctctttcat ttacgaagaa gaccaagaaa aatagctctg
1561 aaggcaataa atcattgagc ttttctgaag tgtttgtgcc tgacctggta aatggaccta
1621 ctaacaaaaa gagtgtaagc actccaccta ggacgagaaa taaatttgca acatttttac
1681 aaaggaaaaa tgaagaaagt ggtgcagttg tggttccagg gaccagaagc aggttttttt
1741 gcagttcaga ttctactgac tgtgtatcaa acaaagtgag catccagcct ctggatgaaa
1801 ctgctgtcac agataaagag aacaatctgc atgaatcaga gtatggagac caagaaggca
1861 agagactggt tgacacagat gtagcacgta attcaagtga tgacattccg aataatcata
1921 ttccaggtga tcatattcca gacaaggcaa cagtgtttac agatgaagag tcctactctt
1981 ttaagagcag caaatttaca aggaccattt caccacccac tttgggaaca ctaagaagtt
2041 gttttagttg gtctggaggt cttggagatt tttcaagaac gccgagcccc tctccaagca
2101 cagcattgca gcagttccga agaaagagcg attcccccac ctctttgcct gagaataata
2161 tgtctgatgt gtcgcagtta aagagcgagg agtccagtga cgatgagtct catcccttac
2221 gagaaggggc atgttcttca cagtcccagg aaagtggaga attctcactg cagagttcaa
2281 atgcatcaaa gctttctcag tgctctagta aggactctga ttcagaggaa tctgattgca
2341 atattaagtt acttgacagt caaagtgacc agacctccaa gctatgttta tctcatttct
2401 caaaaaaaga cacacctcta aggaacaagg ttcctgggct atataagtcc agttctgcag
2461 actctctttc tacaaccaag atcaaacctc taggacctgc cagagccagt gggctgagca
2521 agaagccggc aagcatccag aagagaaagc atcataatgc cgagaacaag ccggggttac
2581 agatcaaact caatgagctc tggaaaaact ttggatttaa aaaattctga aaagcttcct
2641 ccttgtaaga aacccctgtc cccagtcaga gataacatcc aactaactcc agaagcggaa
2701 gaggatatat ttaacaaacc tgaatgtggc cgtgttcaaa gagcaatatt ccagtaaatg
2761 cagactgctg caaagctttt gcctgcaaga gaatctgatc aatttgaagt ccctgtttgg
2821 gaatgaggca cttatcagca tgaagaattt tttctcattc tgtgccattt taaaaataga
2881 atacattttg tatattaact ttaaaaaaaa aaaaaaaaaa a
//