LOCUS AF040628 5307 bp mRNA linear HUM 13-NOV-1998
DEFINITION Homo sapiens ectodysplasin-A (EDA) mRNA, complete cds.
ACCESSION AF040628
VERSION AF040628.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5307)
AUTHORS Bayes,M., Hartung,A.J., Ezer,S., Pispa,J., Thesleff,I.,
Srivastava,A.K. and Kere,J.
TITLE The anhidrotic ectodermal dysplasia gene (EDA) undergoes
alternative splicing and encodes ectodysplasin-A with deletion
mutations in collagenous repeats
JOURNAL Hum. Mol. Genet. 7 (11), 1661-1669 (1998)
PUBMED 9736768
REFERENCE 2 (bases 1 to 5307)
AUTHORS Srivastava,A.K.
TITLE Direct Submission
JOURNAL Submitted (31-DEC-1997) J.C.Self Research Institute of Human
Genetics, Greenwood Genetic Center, 1 Gregor Mendel Circle,
Greenwood, SC 29646, USA
FEATURES Location/Qualifiers
source 1..5307
/db_xref="H-InvDB:HIT000063612"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq13.1"
gene 1..5307
/gene="EDA"
CDS 243..1418
/gene="EDA"
/note="transmembrane protein with collagenous domains"
/codon_start=1
/product="ectodysplasin-A"
/protein_id="AAC77363.1"
/translation="MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFL
GFFGLSLALHLLTLCCYLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPI
TSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRS
KSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPG
PPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSR
ITMNPKVFKLHPRSGELEVLVDGTYFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTR
SIETGKTNYNTCYTAGVCLLKARQKIAVKMVHADISINMSKHTTFFGAIRLGEAPAS"
BASE COUNT 1294 a 1396 c 1380 g 1229 t
ORIGIN
1 attccctcgg cgggccgagc ctcccctctc tcccgcccct cctcctccct ttcccacccc
61 tcggagtaga gctgcacatg cggctgctcc ctgctccgtc ccgcccagcc actgtcgcgc
121 aggaacgggt ccctgcagcc cccagccgat ggcaggacag tagccgcctg tcagaggtcg
181 tgaacggctg aggcagacgc agcggctccc gggcctcaag agagtggatg tctccggagg
241 ccatgggcta cccggaggtg gagcgcaggg aactcctgcc tgcagcagcg ccgcgggagc
301 gagggagcca gggctgcggg tgtggcgggg cccctgcccg ggcgggcgaa gggaacagct
361 gcctgctctt cctgggtttc tttggcctct cgctggccct ccacctgctg acgttgtgct
421 gctacctaga gttgcgctcg gagttgcggc gggaacgtgg agccgagtcc cgccttggcg
481 gctcgggcac ccctggcacc tctggcaccc taagcagcct cggtggcctc gaccctgaca
541 gccccatcac cagtcacctt gggcagccgt cacctaagca gcagccattg gaaccgggag
601 aagccgcact ccactctgac tcccaggacg ggcaccagat ggccctattg aatttcttct
661 tccctgatga aaagccatac tctgaagaag aaagtaggcg tgttcgccgc aataaaagaa
721 gcaaaagcaa tgaaggagca gatggcccag ttaaaaacaa gaaaaaggga aagaaagcag
781 gacctcctgg acccaatggc cctccaggac ccccaggacc tccaggaccc cagggacccc
841 caggaattcc agggattcct ggaattccag gaacaactgt tatgggacca cctggtcctc
901 caggtcctcc tggtcctcaa ggaccccctg gcctccaggg accttctggt gctgctgata
961 aagctggaac tcgagaaaac cagccagctg tggtgcatct acagggccaa gggtcagcaa
1021 ttcaagtcaa gaatgatctt tcaggtggag tgctcaatga ctggtctcgc atcactatga
1081 accccaaggt gtttaagcta catccccgca gcggggagct ggaggtactg gtggacggca
1141 cctacttcat ctatagtcag gtagaagtat actacatcaa cttcactgac tttgccagct
1201 atgaggtggt ggtggatgag aagcccttcc tgcagtgcac acgcagcatc gagacgggca
1261 agaccaacta caacacttgc tataccgcag gcgtctgcct cctcaaggcc cggcagaaga
1321 tcgccgtcaa gatggtgcac gctgacatct ccatcaacat gagcaagcac accacgttct
1381 ttggggccat caggctgggt gaagcccctg catcctagat tccccccatt ttgcctctgt
1441 ccgtgcccct tccctgggtt tgggagccag gactcccaga acctctaagt gctgctgtgg
1501 agtgaggtgt attggtgttg cagccgcaga gaaatgcccc agtgttattt attccccagt
1561 gactccaggg tgacaaggcc tgcttgactt tccagaatga ccttgagtta acaggacagt
1621 tgatggagcc ccagggttta catgaagcag aaccttcttt ggttccatgt tgactgactt
1681 atggcatgac tcttcaaccc cgaggtccct gttgtcagat ctattgtttg ttgcactaaa
1741 atgaggatcc agggcagcag gccagagaaa gcaaaggtgc actccagact ctgggggtgg
1801 acatctgacc ccaagggggc tgctgctcct ctcttgggta gggtagtggc tggggtggag
1861 tgggaagkga gcattgcagc ctaagaagaa ggccagagag ggaaaaggca ggtgcttttg
1921 gcagagacca taagagaaac ctgccaagga gcatccttgg cagtgggaat gttctttctg
1981 ctctatactg tggcctgcag gagggttgga gtgctcttcc cactccagct gacagccaca
2041 ccgtggcagc ttgctgggct ttgggaagtt tgctgtgctt tggaacaatc acagggaatg
2101 gccacaaacc tgcccgccta agaccctgaa tccgtacttg ggtcacatga ctctcatttt
2161 atttacagct gtgctccaca ctcagaaaat tccctggggt caccttctag ttgcccccat
2221 tcccagcctg actagaactc ctgtcttctt tctccatgga gcctacctct gtctgagaca
2281 ggtgcctaac ctgggacctg tggtcatgtg agtctgggat attctttagc ttacctgggc
2341 acagacagaa ttttccattt attaagcagt acagatgttt ttcatccatt cctaatcaaa
2401 ttctgtctgg ggacgaaggg ttggacggga tgacctccag aagtcccttc aatttctagt
2461 acctgtgact cttagccctc accacagcct tctaaattcc caaatcctag actgctcctg
2521 ggcattagca aggcagagcc tttttacctg gcctagaaag ggcaaggggt gaggatagga
2581 cagagggatt ttgttcaagt ttgctgcaac ccaagtggac gttaggccag gccttatctg
2641 aaaggccagc agctgatgct gtactaaccc agtctttctt cactctggct tcaaaaagcc
2701 acagcagagc attgtcaccg caggtcccca tgctgctccc ctaaagccag gctcaggaga
2761 agccagtgtc taggcactga gcagggatct gccccctagt tcaggtccaa attcaccttc
2821 ccctaaaccc caagcttccc aacagatcat atggtaggac cctcgagagc cttacttcaa
2881 agtgcctggg ctcagcctgg tttctgggtg ctagatccag cccaaacctg ggaaggccag
2941 ccttgtacag tctgctcctc ttgttcctga aatgtgtttc cttttcagga gatggggaat
3001 aatttccttc aggcagctga aattcaccaa gaacagcggg tacttatttc tcaagctgtg
3061 ccttcccttt ctaagcaacc acactgcttg gcccttcaag ggtcagggtg agacgtgatg
3121 ggctaggcct ccgttgtctg gttgctaatg acagccttgc aacccaaggt gaggtgaact
3181 ccaggcatgt gtctggccct aactcctata aagtgcctcg gacagtccgc agttgtagca
3241 gaaaccaaca agaaccactc cttcatgttt ggaaaataat ttctcttgta ttatctcctt
3301 tgaagaaggc aaggctgata atatgacaaa catcattgtt tagatgaggc tcagagaggt
3361 agcactctca gagtgttttg accagtttaa gccgcagacc tggagcttca gccaggtctg
3421 actccaaagc tgttccatta caccacagca ttgtgtggaa tttgaggtct agagagaacc
3481 aataaaagtg gtaattggga actgaaatcc ttgagagttc cggggagaaa cccagagatg
3541 cctgatttca ttcctcgatg gtaatacccg tcctctcggc tgccaggggc tctgtggcaa
3601 aaagagtcag acatttcttt ggaaaacagc gaacagcctt agagctcttg tgttcagaag
3661 aatcttcctg gcacaatgtt ggagcagcag gcctctggga cccacagaac ttgtggcctt
3721 tatgttcttt cacccatcct aggaaccagc caaccatcat gtgtagagcc cctactgtgg
3781 gcaaagtcct cctttcatta ccctacagac agcttacagg agccagcctg cttcccacaa
3841 ctactagtgt gactccttat ctctttccac cataccttag agactttgat actaccaggg
3901 tctctcaggg atggagggaa gacctgaaag agaggactgg ttctgaggcc agaaaggtgt
3961 gaggagagag gaggaaaagt cttcctaatt gtgcccctaa agagcatcct gataccattc
4021 tattctccag acatggaggg gatgataaag gaaataggat ctccactgga cccttgattc
4081 attctgaacc ctccaaagga actctaagag ggcgagggat gatgagggaa gcaataggta
4141 gctggggagc cctattgctg ctaagtcatt ggcaaagtgc aaagcaattt actgatgaga
4201 gaatgtggaa atagatgtgc agtttggaat tatgttggtg tnaatttgcc agaggaccaa
4261 tgcttgcatg gagaatggac gaggacattt gtgggcaagc agatgacaga ggtttgaagg
4321 agaatggcat ggcaggagtc tctgccagtt acttgggctt caacagccaa gctggcacaa
4381 aagacagctg gcggaggctg ctcggctact ggttacctgg agaagtagta tttgcctatt
4441 tcccccttca tccatcctga gccaaatttc ntttgctgaa caggaaagag cyaggaaccc
4501 tggaggtaaa caaagacttt gancctgtnt nagtgtatgt gtttntgtaa cttcctgtgg
4561 agtgcaaata gattcagaga aatttagagc taaaaaggcc cttagaggga atctagccca
4621 acctacattc caccctgtta cttatgtaga aactgaggcc cagagaggga agatgacctg
4681 ccccaagtgg tgagcaagca ccaacctcca gactcagcag agtgaggggg taaagcagtt
4741 cctgtcccac atggccatct tctttcttcc acccacaaac tccaggctgg aagtacttgg
4801 cccccttcag gagcctggcc aggcagggag agagtagctg cagccttcat cagaactctt
4861 cctcctccca aggcattctc ccagctctag cctctggact ggaaagcaca agactggccc
4921 agtgccagca agtccttagg ctactgtaat gctgcctcag gacccatccc tgcctggagg
4981 ctcctctagg ccctgtgagc acaaagaaga aagctgattt ttgtctttta atccatttca
5041 ggactctctc caggagggct cggggtgtgt catttctata ttcctccagc tgggattggg
5101 gggtgggctt tgttgtgaga atggcctgga gcaggcccaa tgctgctttt gggggtcagc
5161 atccagtgtg agatactgtg tatataaact atatataatg tatataaact gggatgtaag
5221 tttgtgtaaa ttaatgtttt attctttgca aataaaacgc tttccccgtc aaaaaaaaaa
5281 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//