LOCUS AF039652 1168 bp mRNA linear HUM 19-APR-2004
DEFINITION Homo sapiens ribonuclease H type II mRNA, complete cds.
ACCESSION AF039652
VERSION AF039652.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1168)
AUTHORS Wu,H., Lima,W.F. and Crooke,S.T.
TITLE Molecular cloning and expression of cDNA for human RNase H
JOURNAL Antisense Nucleic Acid Drug Dev. 8 (1), 53-61 (1998)
PUBMED 9512096
REFERENCE 2 (bases 1 to 1168)
AUTHORS Wu,H., Lima,W. and Crooke,S.
TITLE Direct Submission
JOURNAL Submitted (22-DEC-1997) Molecular Pharmaclogy, Isis
Pharmaceuticals, Inc., 2292 Faraday Ave, Carlsbad, CA 92008, USA
FEATURES Location/Qualifiers
source 1..1168
/db_xref="H-InvDB:HIT000063486"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17p11.2"
CDS 82..942
/function="ribonuclease specific for the RNA strand of a
DNA-RNA hybrid"
/note="RNAase HII"
/codon_start=1
/product="ribonuclease H type II"
/protein_id="AAC09261.1"
/translation="MSWLLFLAHRVALAALPCRRGSRGFGMFYAVRRGRKTGVFLTWN
ECRAQVDRFPAARFKKFATEDEAWAFVRKSASPEVSEGHENQHGQESEAKASKRLREP
LDGDGHESAEPYAKHMKPSVEPAPPVSRDTFSYMGDFVVVYTDGCCSSNGRRRPRAGI
GVYWGPGHPLNVGIRLPGRQTNQRAEIHAACKAIEQAKTQNINKLVLYTDSMFTINGI
TNWVQGWKKNGWKTSAGKEVINKEDFVALERLTQGMDIQWMHVPGHSGFIGNEEADRL
AREGAKQSED"
BASE COUNT 325 a 249 c 349 g 245 t
ORIGIN
1 ggaagtgcgg tgttaagcgc cggcggctcg cgcccacgct gggccgggag tcgaaatgct
61 tcccggtgcc gggagtgagc gatgagctgg cttctgttcc tggcccacag agtcgccttg
121 gccgccttgc cctgccgccg cggctctcgc gggttcggga tgttctatgc cgtgaggagg
181 ggccgcaaga ccggggtctt tctgacctgg aatgagtgca gagcacaggt ggaccggttt
241 cctgctgcca gatttaagaa gtttgccaca gaggatgagg cctgggcctt tgtcaggaaa
301 tctgcaagcc cggaagtttc agaagggcat gaaaatcaac atggacaaga atcggaggcg
361 aaagccagca agcgactccg tgagccactg gatggagatg gacatgaaag cgcagagccg
421 tatgcaaagc acatgaagcc gagcgtggag ccggcgcctc cagttagcag agacacgttt
481 tcctacatgg gagacttcgt cgtcgtctac actgatggct gctgctccag taatgggcgt
541 agaaggccgc gagcaggaat cggcgtttac tgggggccag gccatccttt aaatgtaggc
601 attagacttc ctgggcggca gacaaaccaa agagcggaaa ttcatgcagc ctgcaaagcc
661 attgaacaag caaagactca aaacatcaat aaactggttc tgtatacaga cagtatgttt
721 acgataaatg gtataactaa ctgggttcaa ggttggaaga aaaatgggtg gaagacaagt
781 gcagggaaag aggtgatcaa caaagaggac tttgtggcac tggagaggct tacccagggg
841 atggacattc agtggatgca tgttcctggt cattcgggat ttataggcaa tgaagaagct
901 gacagattag ccagagaagg agctaaacaa tcggaagact gagccatgtg actttagtcc
961 ttgggagaac ttgagccagc ggctgtcttg ctgcctgtac ttactggtgt ggaaaatagc
1021 ctgcaggtag gaccattgca gtgatgggca gatgcgtctt tcacacggaa tcaggcacag
1081 tggccttctg tgacatgtgt ttataaaaaa tggttaagta tataataaat tgaacatctt
1141 ttaaaaaaaa aaaaaaaaaa aaaaaaaa
//