LOCUS AF039597 1983 bp DNA linear HUM 24-JUL-2016
DEFINITION Homo sapiens Ku86 autoantigen related protein 1 (KARP-1) gene,
partial cds.
ACCESSION AF039597
VERSION AF039597.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1983)
AUTHORS Myung,K., He,D.M., Lee,S.E. and Hendrickson,E.A.
TITLE KARP-1: a novel leucine zipper protein expressed from the Ku86
autoantigen locus is implicated in the control of DNA-dependent
protein kinase activity
JOURNAL EMBO J. 16 (11), 3172-3184 (1997)
PUBMED 9214634
REFERENCE 2 (bases 1 to 1983)
AUTHORS Myung,K., Braastad,C., He,D.M. and Hendrickson,E.A.
TITLE KARP-1 is induced by DNA damage in a p53- and ataxia telangiectasia
mutated-dependent fashion
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (13), 7664-7669 (1998)
PUBMED 9636207
REFERENCE 3 (bases 1 to 1983)
AUTHORS Hendrickson,E.A., Myung,K., Braastad,C.D. and He,D.M.
TITLE Direct Submission
JOURNAL Submitted (19-DEC-1997) Molecular and Cellular Biology and
Biochemistry, Brown University, 69 Brown Street, Providence, RI
02912, USA
FEATURES Location/Qualifiers
source 1..1983
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q33-q35"
gene <1..>1983
/gene="KARP-1"
mRNA join(<1..68,186..231,1629..>1983)
/gene="KARP-1"
/product="Ku86 autoantigen related protein 1"
CDS join(<1..68,186..231,1629..>1983)
/gene="KARP-1"
/function="DNA double strand break repair"
/note="DNA binding protein; KARP-1"
/codon_start=2
/product="Ku86 autoantigen related protein 1"
/protein_id="AAC52087.1"
/translation="NPTKISWAWWHTLWSQLPGRLRSLDRTRRETRTTDKICVSGGSN
TTRPRLRRNGENVRMLGGNLRMLGENLRMLGRNLRELGGNLRKLGGNLRMLRVPGHGF
PAPFRPSRKRSGSFRYLPLVHRKRVATRQVPARKKRPXRLRTGNMVRSGNKAAV"
BASE COUNT 507 a 488 c 448 g 538 t
ORIGIN
1 aaaccccaca aaaattagct gggcttggtg gcacacactg tggtcccagc tacctgggag
61 gctgaggtaa gtgaatgctt gagcccaggg gttccaccct gcagagagct atgattgtgc
121 tactggactc cagcctcggc cgagcgacac cctgtctgtt tctttccttt tctctctctc
181 cctagctctg gatcgtacaa gaagggagac aaggaccact gacaagatat ggtatgtgat
241 actaatcaga tttggcttct ttctgtcctg cttcaccaga agctggactc tccttgtttc
301 agtttctccg ctttccacag ataaatcttt tgtttcccgg atagccactt ggcctgtttg
361 ccctttcgtc ccatttttcc ttgtttgctt ctttgtctga aaatttatgc tgtcctgctg
421 cctccgctgg gcttcgtttc cacctttgct ggaggagatt taactgacaa cctcacagat
481 nttccccgcc ccttctgccg aactgatctt tctcttggga aatcttaccc ccacggaaag
541 ggctagtgtc cgtgcctgcc tgcctgcctg ctgcagcccg cgcaaagctg agcggccaag
601 ggcgctgctg ttcctttaaa gtattattaa aaataatatt tcagctttta agtaactcct
661 tgagtttgaa tcaaaagctg gaagaacctc ctgggctcta tgagcacctc tgaatatgtc
721 tgactctaca ttctagaggc ttcaatatat ttataatttt ggctcataga ttctccacat
781 cttttcagct tcaattcttg cttttcccag aaacaatttt caagcaggag agaatattga
841 ttggacttga ttttctcagt ttgggcagag gtttgcagac actttgcagg ttgccagacc
901 cttcgtccag ccacccgtca gctgggggtc atatggtata gaaagcagtc atttctatgc
961 aaggtactgc ttgggcctgc ctccctcaaa ggggtagggg atgcgggctg gacaaagggc
1021 tcgtgatcaa gtaaagcact gtgatgacag ctgctatttc tatatctccc tagacttgtc
1081 ttctaaatta aaccttgact cctcccttcc aagctggagc cactgctaac tactgggaga
1141 gccttagcag ataaagtctc atgcctccag gcgtttgtgc atcccatttt ctctgcagag
1201 tagaatctcc cttctacttt tgtgctcctg gggacgtcct actcttcttc cccagttggc
1261 tctaaggtta tcacatcggt gaagtgtttc attatcactt tttagaagaa actgagtctt
1321 ttagagaagt taagtgactt tctcgattca tactcatact caagaaaatc taactccaca
1381 ataaccaaaa ataaaaagta gaaaaaaacc cacaagtgat gagaaaaaaa aaaaaatcaa
1441 aagttataaa aaataaatga aaaaatgaaa ttaaaggaaa aaagattttt taaaaaagta
1501 aaaaaaagaa aagaaatcta actccagagc tctgacacaa aatgccttag gtgttattct
1561 caatgagaga aaagggacgt gaatctttaa gtgattaagt gaatctttaa gtaaatctgt
1621 cgtactagcg tttcaggcgg ctcaaacacc acacgccccc gactacggcg gaatggagag
1681 aatgtgcgca tgctcggcgg gaatctgcgc atgctcggag agaatctgcg catgctcggc
1741 cggaatctgc gcgagctcgg cgggaatctg cgcaagctcg gcgggaatct gcgcatgctc
1801 agagttccgg ggcacggttt ccccgcccct ttcaggccta gcaggaaacg aagcggctct
1861 ttccgctatc tgccgcttgt ccaccggaag cgagttgcga cacggcaggt tcccgcccgg
1921 aagaagcgac caragcgcct gaggaccggc aacatggtgc ggtcggggaa taaggcagct
1981 gtt
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