LOCUS AF038009 1768 bp mRNA linear HUM 15-APR-1998
DEFINITION Homo sapiens tyrosylprotein sulfotransferase-1 mRNA, complete cds.
ACCESSION AF038009
VERSION AF038009.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1768)
AUTHORS Ouyang,Y., Lane,W.S. and Moore,K.L.
TITLE Tyrosylprotein sulfotransferase: purification and molecular cloning
of an enzyme that catalyzes tyrosine O-sulfation, a common
posttranslational modification of eukaryotic proteins
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (6), 2896-2901 (1998)
PUBMED 9501187
REFERENCE 2 (bases 1 to 1768)
AUTHORS Ouyang,Y.B., Lane,W.S. and Moore,K.L.
TITLE Direct Submission
JOURNAL Submitted (10-DEC-1997) Cardiovascular Biology, Oklahoma Medical
Research Foundation, 825 NE 13th Street, Mailstop #45, Oklahoma
City, OK 73104, USA
FEATURES Location/Qualifiers
source 1..1768
/db_xref="H-InvDB:HIT000063384"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
5'UTR 1..81
CDS 82..1194
/function="O-sulfation of tyrosine residues within acidic
motifs of polypeptides"
/note="TPST-1; type II transmembrane protein; Golgi
enzyme"
/codon_start=1
/product="tyrosylprotein sulfotransferase-1"
/protein_id="AAC13552.1"
/translation="MVGKLKQNLLLACLVISSVTVFYLGQHAMECHHRIEERSQPVKL
ESTRTTVRTGLDLKANKTFAYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETR
VIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKD
PFALKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLTKWNRA
IETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNHSVLHHEEMIGKAG
GVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPN
YGKPDPKIIENTRRVYKGEFQLPDFLKEKPQTEQVE"
misc_feature 259..267
/experiment="experimental evidence, no additional details
recorded"
/note="N-linked; glycosylation site"
misc_feature 865..873
/experiment="experimental evidence, no additional details
recorded"
/note="N-linked; glycosylation site"
regulatory 1749..1754
/regulatory_class="polyA_signal_sequence"
polyA_site 1768
BASE COUNT 497 a 367 c 407 g 496 t
ORIGIN
1 gtagactgtc catggcctga acattttccg aaaatcattt tgagcaaaat atctgtttaa
61 taacaagata accacatcaa gatggttgga aagctgaagc agaacttact attggcatgt
121 ctggtgatta gttctgtgac tgtgttttac ctgggccagc atgccatgga atgccatcac
181 cggatagagg aacgtagcca gccagtcaaa ttggagagca caaggaccac tgtgagaact
241 ggcctggacc tcaaagccaa caaaaccttt gcctatcaca aagatatgcc tttaatattt
301 attggrggtg tgcctcggag tggaaccaca ctcatgaggg ccatgctgga cgcacatcct
361 gacattcgct gtggagagga aaccagggtc attccccgaa tcctggccct gaagcagatg
421 tggtcacggt caagtaaaga gaagatccgc ctggatgagg ctggtgttac tgatgaagtg
481 ctggattctg ccatgcaagc cttcttacta gaaattatcg ttaagcatgg ggagccagcc
541 ccttatttat gtaataaaga tccttttgcc ctgaaatctt taacttacct ttctaggtta
601 ttccccaatg ccaaatttct cctgatggtc cgagatggcc gggcatcagt acattcaatg
661 atttctcgaa aagttactat agctggattt gatctgaaca gctataggga ctgtttgaca
721 aagtggaatc gtgctataga gaccatgtat aaccagtgta tggaggttgg ttataaaaag
781 tgcatgttgg ttcactatga acaacttgtc ttacatcctg aacggtggat gagaacactc
841 ttaaagttcc tccagattcc atggaaccac tcagtattgc accatgaaga gatgattggg
901 aaagctgggg gagtgtctct gtcaaaagtg gagagatcta cagaccaagt aatcaagcca
961 gtcaatgtag gagctctatc aaaatgggtt gggaagatac cgccagatgt tttacaagac
1021 atggcagtga ttgctcctat gcttgccaag cttggatatg acccatatgc caacccacct
1081 aactacggaa aacctgatcc caaaattatt gaaaacactc gaagggtcta taagggagaa
1141 ttccaactac ctgactttct taaagaaaaa ccacagactg agcaagtgga gtagcagaac
1201 caggagcctc ttccatacat gaggaaagat tgctgccttt tcagcagaag ggaaattcct
1261 aggattggct gtcccctgcc aagcttggtg gagcgtctgc accttggctg cgccgcctgt
1321 gcatttgcca gtttcctccc actgagagga tggaggtgtc cgcacagctt tgggcctcgt
1381 gagggatctg cctcctgagc aaagagctct tgatcccgat ttcatgcaca gccctgcagt
1441 aaggagccca gaaggaacat gtgtttcctg ttaaaactcc tcttgttctc ttttcttaca
1501 ttatgacgtt tgttttcaag gagagggttt aaaaatggga tcctgtaagc agacttgggc
1561 agtctccttt tgaaataggt tgtctgtaca tgttctaatg ttttgtagaa cacgtgtgcc
1621 tgtttaagtg tattgatgtg aataatatta aatatcctaa ttatttaatt cattgtattg
1681 tttctgagaa gttgggaaat taccattata catttacaac ctaatgactt ttgtatttta
1741 tttttcaaaa taaaagcttt caatgtga
//