LOCUS AF036581 1169 bp mRNA linear HUM 28-JAN-1998
DEFINITION Homo sapiens tumor necrosis factor superfamily member LIGHT mRNA,
complete cds.
ACCESSION AF036581
VERSION AF036581.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1169)
AUTHORS Mauri,D.N., Ebner,R., Montgomery,R.I., Kochel,K.D., Cheung,T.C.,
Yu,G.-L., Ruben,S., Murphy,M., Eisenberg,R.J., Cohen,G.H.,
Spear,P.G. and Ware,C.F.
TITLE LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha
are ligands for herpesvirus entry mediator
JOURNAL Immunity 8 (1), 21-30 (1998)
PUBMED 9462508
REFERENCE 2 (bases 1 to 1169)
AUTHORS Ebner,R., Kochel,K.D. and Ware,C.F.
TITLE Direct Submission
JOURNAL Submitted (02-DEC-1997) Division of Molecular Immunology, La Jolla
Institute for Allergy and Immunology, 10355 Science Center Drive,
San Diego, CA 92121, USA
FEATURES Location/Qualifiers
source 1..1169
/db_xref="H-InvDB:HIT000063338"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/cell_type="peripheral blood mononuclear cells activated
with phorbol ester and phytohemagglutinin for 12 hr"
CDS 49..771
/function="ligand for herpesvirus entry mediator (HVEM)
and lymphotoxin-beta receptor (LTbR)"
/codon_start=1
/product="tumor necrosis factor superfamily member LIGHT"
/protein_id="AAC39563.1"
/translation="MEESVVRPSVFVVDGQTDIPFTRLGRSHRRQSCSVARVGLGLLL
LLMGAGLAVQGWFLLQLHWRLGEMVTRLPDGPAGSWEQLIQERRSHEVNPAAHLTGAN
SSLTGSGGPLLWETQLGLAFLRGLSYHDGALVVTKAGYYYIYSKVQLGGVGCPLGLAS
TITHGLYKRTPRYPEELELLVSQQSPCGRATSSSRVWWDSSFLGGVVHLEAGEEVVVR
VLDERLVRLRDGTRSYFGAFMV"
repeat_region 855..1140
/rpt_family="Alu"
/rpt_type=dispersed
polyA_site 1140
BASE COUNT 254 a 314 c 386 g 215 t
ORIGIN
1 gaggttgaag gacccaggcg tgtcagccct gctccagaga ccttgggcat ggaggagagt
61 gtcgtacggc cctcagtgtt tgtggtggat ggacagaccg acatcccatt cacgaggctg
121 ggacgaagcc accggagaca gtcgtgcagt gtggcccggg tgggtctggg tctcttgctg
181 ttgctgatgg gggctgggct ggccgtccaa ggctggttcc tcctgcagct gcactggcgt
241 ctaggagaga tggtcacccg cctgcctgac ggacctgcag gctcctggga gcagctgata
301 caagagcgaa ggtctcacga ggtcaaccca gcagcgcatc tcacaggggc caactccagc
361 ttgaccggca gcggggggcc gctgttatgg gagactcagc tgggcctggc cttcctgagg
421 ggcctcagct accacgatgg ggcccttgtg gtcaccaaag ctggctacta ctacatctac
481 tccaaggtgc agctgggcgg tgtgggctgc ccgctgggcc tggccagcac catcacccac
541 ggcctctaca agcgcacacc ccgctacccc gaggagctgg agctgttggt cagccagcag
601 tcaccctgcg gacgggccac cagcagctcc cgggtctggt gggacagcag cttcctgggt
661 ggtgtggtac acctggaggc tggggaggag gtggtcgtcc gtgtgctgga tgaacgcctg
721 gttcgactgc gtgatggtac ccggtcttac ttcggggctt tcatggtgtg aaggaaggag
781 cgtggtgcat tggacatggg tctgacacgt ggagaactca gagggtgcct caggggaaag
841 aaaactcacg aagcagaggc tgggcgtggt ggctctcgcc tgtaatccca gcactttggg
901 aggccaaggc aggcggatca cctgaggtca ggagttcgag accagcctgg ctaacatggc
961 aaaaccccat ctctactaaa aatacaaaaa ttagccggac gtggtggtgc ctgcctgtaa
1021 tccagctact caggaggctg aggcaggata attttgctta aacccgggag gcggaggttg
1081 cagtgagccg agatcacacc actgcactcc aacctgggaa acgcagtgag actgtgcctc
1141 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//