LOCUS AF035960 2204 bp mRNA linear HUM 19-FEB-1998
DEFINITION Homo sapiens transglutaminase X mRNA, alternatively spliced full
length form, complete cds.
ACCESSION AF035960
VERSION AF035960.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2204)
AUTHORS Aeschlimann,D., Koeller,M.K., Allen-Hoffmann,B.L. and Mosher,D.F.
TITLE Isolation of a cDNA encoding a novel member of the transglutaminase
gene family from human keratinocytes. Detection and identification
of transglutaminase gene products based on reverse
transcription-polymerase chain reaction with degenerate primers
JOURNAL J. Biol. Chem. 273 (6), 3452-3460 (1998)
PUBMED 9452468
REFERENCE 2 (bases 1 to 2204)
AUTHORS Aeschlimann,D. and Koeller,M.K.
TITLE Direct Submission
JOURNAL Submitted (26-NOV-1997) Orthopedic Surgery, University of
Wisconsin, F4/312 Clinical Science Center, 600 Highland Ave,
Madison, WI 53792, USA
FEATURES Location/Qualifiers
source 1..2204
/db_xref="H-InvDB:HIT000063320"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="primary keratinocytes"
/tissue_type="foreskin"
CDS 9..2171
/EC_number="2.3.2.13"
/note="alternatively spliced, full length form; also
expressed in fetal skin, MG-63 osteosarcoma cells, and HEL
erythroleukemia cells; expression induced several fold in
differentiating keratinocytes"
/codon_start=1
/product="transglutaminase X"
/protein_id="AAC02978.1"
/translation="MAQGLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLY
FRNRSFQPGLDNIIFVVETGPLSDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEV
SLCAPPTAAVGRYLLKIHIDSFQGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEY
VMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSP
VYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQWNATGCQPVRYG
QCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRILGNKKKDTIW
NFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGEVDLNYDT
PFVFSMVNADCMSWLVQGGKEQKLHQDTSSVGNFISTKSIQSDERDDITENYKYEEGS
LQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDVVQVS
LKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAFIT
LSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITI
NVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASI
ILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYVDFAL"
BASE COUNT 559 a 605 c 581 g 459 t
ORIGIN
1 cagctaccat ggcccaaggg ctagaagtgg ccctcacaga cctccagagc tccagaaata
61 atgtgcggca ccacacggag gagatcactg tggaccacct gcttgttcgc cggggccagg
121 ccttcaacct caccctgtac ttcaggaacc ggagcttcca gccaggcctg gacaacatca
181 tcttcgtggt tgaaactgga ccgctgtcag acctggcctt ggggactcgg gctgtgttca
241 gcctggcacg ccatcacagc cccagcccct ggattgcctg gctggagacc aatggggcca
301 cctccacaga ggtgagcttg tgcgctcctc ccacggcggc cgtgggtcgg tacctcttga
361 aaatccacat cgactccttc caggggtctg tgacggccta ccagctaggg gagttcatcc
421 tgcttttcaa tccctggtgc ccagaggatg ctgtctactt ggacagtgaa ccccagaggc
481 aggagtatgt catgaatgat tatggcttca tctaccaagg cagcaagaac tggatccgcc
541 catgtccctg gaactatgga cagtttgaag acaaaatcat agacatctgc ctgaagctgc
601 tagacaagag cctgcacttc cagactgacc cagccacaga ctgtgctctg cggggaagcc
661 ccgtctacgt cagcagagtg gtgtgtgcca tgatcaacag caatgatgat aatggggtgc
721 tcaatggaaa ctggagtgag aattacacag acggcgccaa ccctgcggag tggacgggca
781 gcgtggccat cctgaagcag tggaacgcca caggctgcca gcccgtgcgc tacgggcaat
841 gctgggtctt tgctgccgtc atgtgcacag tgatgaggtg tctggggatc cctacccgtg
901 tgatcaccaa cttcgactct ggccacgata cagatggaaa cctgatcata gatgagtatt
961 atgacaacac aggcaggatt ttggggaata agaagaagga tactatctgg aacttccatg
1021 tctggaatga gtgctggatg gcccggaagg atctgccccc tgcatatgga ggctggcagg
1081 tgctggacgc cacacctcag gagatgagca acggcgtcta ctgctgtggc cctgcctctg
1141 tcagagccat caaagaagga gaagtggacc tgaactatga cacgcccttt gtgttttcga
1201 tggtgaatgc tgactgcatg tcctggctcg tccagggagg gaaggagcag aagcttcacc
1261 aggacacgag ttctgttggc aattttatca gcacaaagag catccagagt gacgagcggg
1321 atgacatcac agagaactac aagtatgaag aaggatccct ccaggagagg caggtgtttc
1381 tgaaggctct gcagaagctg aaggctagaa gcttccatgg ctcccaaaga ggagcagagt
1441 tgcaaccttc caggcccaca tcactgagcc aggacagccc tcggagcctg catacacctt
1501 cccttcgacc cagtgatgtg gtgcaagtct ccctgaaatt caagctgctc gacccgccca
1561 acatgggcca ggatatatgc tttgtcctgc tggccctcaa catgtcctcc cagttcaagg
1621 acctcaaagt gaacctgagt gcccagtctc tgctgcacga tggcagcccc ctgtccccat
1681 tctggcagga cacagcgttc atcacactct ctcctaaaga agcaaagacc tacccctgca
1741 aaatctccta ttcccagtac agccagtacc tgtcaacaga caagctgatc cgcatcagtg
1801 ccctgggtga agagaaaagc agtcctgaga aaatcctggt gaacaagatc atcaccttat
1861 cttatccaag catcacgatt aatgttctag gagcagccgt tgtgaaccag ccactctcca
1921 tacaggtgat attttcaaac cccctctcgg agcaggttga ggactgtgtg ctgactgtgg
1981 aaggaagtgg cctcttcaag aaacagcaga aagtcttcct tggagtcctc aaaccccaac
2041 accaagcaag catcattctg gagaccgtcc ccttcaagag tggacaaagg cagatccaag
2101 ctaatatgag aagcaacaag tttaaggaca ttaagggtta caggaatgtt tatgtagact
2161 ttgcattata aattctggaa caacgcgcca gacgtgtgag tttc
//