LOCUS AF035933 3654 bp mRNA linear HUM 20-JUN-1998
DEFINITION Homo sapiens protein kinase mRNA, complete cds.
ACCESSION AF035933
VERSION AF035933.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3654)
AUTHORS Donadelli,R., Benatti,L., Remuzzi,A., Morigi,M., Gullans,S.R.,
Benigni,A., Remuzzi,G. and Noris,M.
TITLE Identification of a novel gene--SSK1--in human endothelial cells
exposed to shear stress
JOURNAL Biochem. Biophys. Res. Commun. 246 (3), 881-887 (1998)
PUBMED 9618306
REFERENCE 2 (bases 1 to 3654)
AUTHORS Donadelli,R., Noris,M., Benatti,L., Orisio,S. and Remuzzi,G.
TITLE Direct Submission
JOURNAL Submitted (26-NOV-1997) Dept. of Kidney Research, M. Negri Inst.
for Pharmacological Research, Via Gavazzeni, 11, Bergamo, BG 24100,
Italy
FEATURES Location/Qualifiers
source 1..3654
/db_xref="H-InvDB:HIT000063315"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="endothelial"
/tissue_type="umbilical vein"
CDS 122..3274
/codon_start=1
/product="protein kinase"
/protein_id="AAC23736.1"
/translation="MAAVKKEGGALSEAMSLEGDEWELSKENVQPLRQGRIMSTLQGA
LAQESACNNTLQQQKRAFEYEIRFYTGNDPLDVWDRYISWTEQNYPQGGKESNMSTLL
ERAVEALQGEKRYYSDPRFLNLWLKLGRLCNEPLDMYSYLHNQGIGVSLAQFYISWAE
EYEARENFRKADAIFQEGIQQKAEPLERLQSQHRQFQARVSRQTLLALEKEEEEEVFE
SSVPQRSTLAELKSKGKKTARAPIIRVGGVFKAPSQNRGLQNPFPQQMQNNSRITVFD
ENADEASTAELSKPTVQPWIAPPMPRAKENELQAGPWNTGRSLEHRPRGNTASLIAVP
AVLPSFTPYVEETAQQPVMTPCKIEPSINHILSTRKPGKEEGDPLQRVQSHQQASEEK
KEKMMYCKEKIYAGVGEFSFEEIRAEVFRKKLKEQREAELLTSAEKRAEMQKQIEEME
KKLKEIQTTQQERTGDQQEETMPTKETTKLQIASESQKIPGMTLSSSVCQVNCCARET
SLAENIWQEQPHSKGPSVPFSIFDEFLLSEKKNKSPPADPPRVLAQRRPLAVLKTSES
ITSNEDVSPDVCDEFTGIEPLSEDAIITGFRNVTICPNPEDTCDFARAARFVSTPFHE
IMSLKDLPSDPERLLPEEDLDVKTSEDQQTACGTIYSQTLSIKKLSPIIEDSREATHS
SGFSGSSASVASTSSIKCLQIPEKLELTNETSENPTQSPWCSQYRRQLLKSLPELSAS
AELCIEDRPMPKLEIEKEIELGNEDYCIKREYLICEDYKLFWVAPRNSAELTVIKVSS
QPVPWDFYINLKLKERLNEDFDHFCSCYQYQDGCIVWHQYINCFTLQDLLQHSEYITH
EITVLIIYNLLTIVEMLHKAEIVHGDLSPRCLILRNRIHDPYDCNKNNQALKIVDFSY
SVDLRVQLDVFTLSGFRTVQILEGQKILANCSSPYQVDLFGIADLAHLLLFKEHLQVF
WDGSFWKLSQNISELKDGELWNKFFVRILNANDEATVSVLGELAAEMNGVFDTTFQSH
LNKALWKVGKLTSPGALLFQ"
BASE COUNT 1141 a 736 c 823 g 954 t
ORIGIN
1 tcgtgtgcgt gccttggtcg cttctgtagc tccgagggca ggttgcggaa gaaagcccag
61 gcggtctgtg gcccagaggg aaggcctgca gcaggacgag gacctgagcc aggaatgcag
121 gatggcggcg gtgaagaagg aagggggtgc tctgagtgaa gccatgtccc tggagggaga
181 tgaatgggaa ctgagtaaag aaaatgtaca acctttaagg caagggcgga tcatgtccac
241 gcttcaggga gcactggcac aagaatctgc ctgtaacaat actcttcagc agcagaaacg
301 ggcatttgaa tatgaaattc gattttacac tggaaatgac cctctggatg tttgggatag
361 gtatatcagc tggacagagc agaactatcc tcaaggtggg aaagagagta atatgtcaac
421 gttattagaa agagctgtag aagcactaca aggagaaaaa cgatattata gtgatcctcg
481 atttctcaat ctctggctta aattagggcg tttatgcaat gagcctttgg atatgtacag
541 ttacttgcac aaccaaggga ttggtgtttc acttgctcag ttctatatct catgggcaga
601 agaatatgaa gctagagaaa actttaggaa agcagatgcg atatttcagg aagggattca
661 acagaaggct gaaccactag aaagactaca gtcccagcac cgacaattcc aagctcgagt
721 gtctcggcaa actctgttgg cacttgagaa agaagaagag gaggaagttt ttgagtcttc
781 tgtaccacaa cgaagcacac tagctgaatt aaagagcaaa gggaaaaaga cagcaagagc
841 tccaatcatc cgtgtaggag gtgttttcaa ggctccaagc cagaacagag gactccaaaa
901 tccatttcct caacagatgc aaaataatag tagaattact gtttttgatg aaaatgctga
961 tgaggcttct acagcagagt tgtctaagcc tacagtccag ccatggatag caccccccat
1021 gcccagggcc aaagagaatg agctgcaagc aggcccttgg aacacaggca ggtccttgga
1081 acacaggcct cgtggcaata cagcttcact gatagctgta cccgctgtgc ttcccagttt
1141 cactccatat gtggaagaga ctgcacaaca gccagttatg acaccatgta aaattgaacc
1201 tagtataaac cacatcctaa gcaccagaaa gcctggaaag gaagaaggag atcctctaca
1261 aagggttcag agccatcagc aagcgtctga ggagaagaaa gagaagatga tgtattgtaa
1321 ggagaagatt tatgcaggag taggggaatt ctcctttgaa gaaattcggg ctgaagtttt
1381 ccggaagaaa ttaaaagagc aaagggaagc cgagctattg accagtgcag agaagagagc
1441 agaaatgcag aaacagattg aagagatgga gaagaagcta aaagaaatcc aaactactca
1501 gcaagaaaga acaggtgatc agcaagaaga gacgatgcct acaaaggaga caactaaact
1561 gcaaattgct tccgagtctc agaaaatacc aggaatgact ctatccagtt ctgtttgtca
1621 agtaaactgt tgtgccagag aaacttcact tgcggagaac atttggcagg aacaacctca
1681 ttctaaaggt cccagtgtac ctttctccat ttttgatgag tttcttcttt cagaaaagaa
1741 gaataaaagt cctcctgcag atcccccacg agttttagct caacgaagac cccttgcagt
1801 tctcaaaacc tcagaaagca tcacctcaaa tgaagatgtg tctccagatg tttgtgatga
1861 atttacagga attgaaccct tgagcgagga tgccattatc acaggcttca gaaatgtaac
1921 aatttgtcct aacccagaag acacttgtga ctttgccaga gcagctcgtt ttgtatccac
1981 tccttttcat gagataatgt ccttgaagga tctcccttct gatcctgaga gactgttacc
2041 ggaagaagat ctagatgtaa agacctctga ggaccagcag acagcttgtg gcactatcta
2101 cagtcagact ctcagcatca agaagctgag cccaattatt gaagacagtc gtgaagccac
2161 acactcctct ggcttctctg gttcttctgc ctcggttgca agcacctcct ccatcaaatg
2221 tcttcaaatt cctgagaaac tagaacttac taatgagact tcagaaaacc ctactcagtc
2281 accatggtgt tcacagtatc gcagacagct actgaagtcc ctaccagagt taagtgcttc
2341 tgcagagttg tgtatagaag acagaccaat gcctaagttg gaaattgaga aggaaattga
2401 attaggtaat gaggattact gcattaaacg agaataccta atatgtgaag attacaagtt
2461 attctgggtg gcgccaagaa actctgcaga attaacagta ataaaggtat cttctcaacc
2521 tgtcccatgg gacttttata tcaacctcaa gttaaaggaa cgtttaaatg aagattttga
2581 tcatttttgc agctgttatc aatatcaaga tggctgtatt gtttggcacc aatatataaa
2641 ctgcttcacc cttcaggatc ttctccaaca cagtgaatat attacccatg aaataacagt
2701 gttgattatt tataaccttt tgacaatagt ggagatgcta cacaaagcag aaatagtcca
2761 tggtgacttg agtccaaggt gtctgattct cagaaacaga atccacgatc cctatgattg
2821 taacaagaac aatcaagctt tgaagatagt ggacttttcc tacagtgttg accttagggt
2881 gcagctggat gtttttaccc tcagcggctt tcggactgta cagatcctgg aaggacaaaa
2941 gatcctggct aactgttctt ctccctacca ggtagacctg tttggtatag cagatttagc
3001 acatttacta ttgttcaagg aacacctaca ggtcttctgg gatgggtcct tctggaaact
3061 tagccaaaat atttctgagc taaaagatgg tgaattgtgg aataaattct ttgtgcggat
3121 tctgaatgcc aatgatgagg ccacagtgtc tgttcttggg gagcttgcag cagaaatgaa
3181 tggggttttt gacactacat tccaaagtca cctgaacaaa gccttatgga aggtagggaa
3241 gttaactagt cctggggctt tgctctttca gtgagctagg caatcaagtc tcacagattg
3301 ctgcctcaga gcaatggttg tattgtggaa cactgaaact gtatgtgctg taatttaatt
3361 taggacacat ttagatgcac taccattgct gttctacttt ttggtacagg tatattttga
3421 cgtcactgat attttttata cagtgatata cttactcatg gccttgtcta acttttgtga
3481 agaactattt tattctaaac agactcatta caaatggtta ccttgttatt taacccattt
3541 gtctctactt ttcccctgta cttttcccat ttgtaatttg taaaatgttc tcttatgatc
3601 accatgtatt ttgtaaataa taaaatagta tctgttaaaa aaaaaaaaaa aaaa
//