LOCUS AF035483 2802 bp mRNA linear HUM 27-JUN-1998
DEFINITION Homo sapiens phospholipase D2 (PLD2) mRNA, complete cds.
ACCESSION AF035483
VERSION AF035483.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2802)
AUTHORS Lopez,I., Arnold,R.S. and Lambeth,J.D.
TITLE Cloning and initial characterization of a human phospholipase D2
(hPLD2). ADP-ribosylation factor regulates hPLD2
JOURNAL J. Biol. Chem. 273 (21), 12846-12852 (1998)
PUBMED 9582313
REFERENCE 2 (bases 1 to 2802)
AUTHORS Lopez,I. and Lambeth,J.D.
TITLE Direct Submission
JOURNAL Submitted (21-NOV-1997) Biochemistry, Emory University, 1510
Clifton Road, Atlanta, GA 30322, USA
FEATURES Location/Qualifiers
source 1..2802
/db_xref="H-InvDB:HIT000063267"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="B lymphocyte"
gene 1..2802
/gene="PLD2"
CDS 1..2802
/gene="PLD2"
/function="cleaves phosphatidylcholine to phosphatidic
acid and choline"
/codon_start=1
/product="phospholipase D2"
/protein_id="AAC24498.1"
/translation="MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFL
AIYELQSLKVHPLVFAPGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKK
KYRHFQELHRDLLRHKVLMSLLPLARFAVAYSPARDAGNREMPSLPRAGPEGSTRHAA
SKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRV
PGLTCCGRDQVCYRWSKRWLVVKDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEA
RHGVRIDTSHRSLILKCSSYRQARWWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTL
ARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAE
EGVRVSILLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQ
VVAFLGGLDLAYGRWDDLHYRLTDLGDSSESAASQPPTPRPDSPATPDLSHNQFFWLG
KDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGLPARDLARHFIQRWNFT
KTTKAKYKTPIYPYLLPKSTSTANQLPFTLPGGQCTTVQVLRSVDRWSAGTLENSILN
AYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHKQGWCYRVYVLLP
LLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGLRT
HGELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEP
SLIDGAEYQAGRFALSLRKHCFGVILGANTRPDLDLRDPICDDFFQLWQDMAESNANI
YEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQVQGHLVHFPLKFLEDE
SLLPPLGSKEGMIPLEVWT"
BASE COUNT 596 a 824 c 789 g 593 t
ORIGIN
1 atgacggcga cccctgagag cctcttcccc actggggacg aactggactc cagccagctc
61 cagatggagt ccgatgaggt ggacaccctg aaggagggag aggacccagc cgaccggatg
121 cacccgtttc tggccatcta tgagcttcag tctctgaaag tgcacccctt ggtgttcgca
181 cctggggtcc ctgtcacagc ccaggtggtg ggcaccgaaa gatataccag cggatccaag
241 gtgggaacct gcactctgta ttctgtccgc ttgactcacg gcgacttttc ctggacaacc
301 aagaagaaat accgtcattt tcaggagctg catcgggacc tcctgagaca caaagtcttg
361 atgagtctgc tccccctggc tcgatttgcc gttgcctatt ctccagcccg agatgcaggc
421 aacagagaga tgccctctct accccgggca ggtcctgagg gctccaccag acatgcagcc
481 agcaaacaga aatacctgga gaattacctc aaccgtctct tgaccatgtc tttctatcgc
541 aactaccatg ccatgacaga gttcctggaa gtcagtcagc tgtcctttat cccggacttg
601 ggccgcaaag gactggaggg gatgatccgg aagcgctcag gtggccaccg tgttcctggc
661 ctcacctgct gtggccgaga ccaagtttgt tatcgctggt ccaagaggtg gctggtggtg
721 aaggactcct tcctgctgta catgtgcctc gagacaggtg ccatctcatt tgttcagctc
781 tttgaccctg gctttgaggt gcaagtgggg aaaaggagca cggaggcacg gcacggcgtg
841 cggatcgata cctcccacag gtccttgatt ctcaagtgca gcagctaccg gcaggcacgg
901 tggtgggccc aagagatcac tgagctggcg cagggcccag gcagagactt cctacagctg
961 caccggcatg acagctacgc cccaccccgg cctgggacct tggcccggtg gtttgtgaat
1021 ggggcaggtt actttgctgc tgtggcagat gccatccttc gagctcaaga ggagattttc
1081 atcacagact ggtggttgag tcctgaggtt tacctgaagc gtccggccca ttcagatgac
1141 tggagactgg acatcatgct caagaggaag gcggaggaag gtgtccgtgt gtctattctg
1201 ctgtttaaag aagtggaatt ggccttgggc atcaacagtg gctatagcaa gagggcgctg
1261 atgctgctgc accccaacat aaaggtgatg cgtcacccag accaagtgac gttgtgggcc
1321 catcatgaga agctcctggt ggtggaccaa gtggtagcat tcctgggggg actggacctt
1381 gcctatggcc gctgggatga cctgcactac cgactgactg accttggaga ctcctctgaa
1441 tcagctgcct cccagcctcc caccccgcgc ccagactcac cagccacccc agacctctct
1501 cacaaccaat tcttctggct gggcaaggac tacagcaatc ttatcaccaa ggactgggtg
1561 cagctggacc ggcctttcga agatttcatt gacagggaga cgacccctcg gatgccatgg
1621 cgggacgttg gggtggtcgt ccatggccta ccggcccggg accttgcccg gcacttcatc
1681 cagcgctgga acttcaccaa gaccaccaag gccaagtaca agactcccat atacccctac
1741 ctgcttccca agtctaccag cacggccaat cagctcccct tcacacttcc aggagggcag
1801 tgcaccaccg tacaggtctt gcgatcagtg gaccgctggt cagcagggac tctggagaac
1861 tccatcctca atgcctacct gcacaccatc agggagagcc agcacttcct ctacattgag
1921 aatcagttct tcattagctg ctcagatggg cggacggttc tgaacaaggt gggcgatgag
1981 attgtggaca gaatcctgaa ggcccacaaa caggggtggt gttaccgagt ctacgtgctt
2041 ttgcccttac tccctggctt cgagggtgac atctccacgg gcggtggcaa ctccatccag
2101 gccattctgc actttactta caggaccctg tgtcgtgggg agtattcaat cctgcatcgc
2161 cttaaagcag ccatggggac agcatggcgg gactatattt ccatctgcgg gcttcgtaca
2221 cacggagagc tgggcgggca ccccgtctcg gagctcatct acatccacag caaggtgctc
2281 atcgcagatg accggacagt catcattggt tctgcaaaca tcaatgaccg gagcttgctg
2341 gggaagcggg acagtgagct ggccgtgctg atcgaggaca cagagacgga accatccctc
2401 atagatgggg cagagtatca ggcgggcagg tttgccttga gtctgcggaa gcactgcttc
2461 ggtgtgattc ttggagcaaa tacccggcca gacttggatc tccgagaccc catctgtgat
2521 gacttcttcc agttgtggca agacatggct gagagcaacg ccaatatcta tgagcagatc
2581 ttccgctgcc tgccatccaa tgccacgcgt tccctgcgga ctctccggga gtacgtggcc
2641 gtggagccct tggccacggt cagtcccccc ttggctcggt ctgagctcac ccaggtccag
2701 ggccacctgg tccacttccc cctcaagttc ctagaggatg agtctttgct gcccccgctg
2761 ggtagcaagg agggcatgat ccccctagaa gtgtggacat ag
//