LOCUS AF035154 2384 bp mRNA linear HUM 29-OCT-1998
DEFINITION Homo sapiens regulator of G-protein signalling 11 (RGS11) mRNA,
alternative splice variant, complete cds.
ACCESSION AF035154
VERSION AF035154.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2384)
AUTHORS Snow,B.E., Krumins,A.M., Brothers,G.M., Lee,S.F., Wall,M.A.,
Chung,S., Mangion,J., Arya,S., Gilman,A.G. and Siderovski,D.P.
TITLE A G protein gamma subunit-like domain shared between RGS11 and
other RGS proteins specifies binding to Gbeta5 subunits
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (22), 13307-13312 (1998)
PUBMED 9789084
REFERENCE 2 (bases 1 to 2384)
AUTHORS Snow,B.E. and Siderovski,D.P.
TITLE Direct Submission
JOURNAL Submitted (20-NOV-1997) Quantitative Biology, Amgen Institute, 620
University Avenue, Suite 706, Toronto, ON M5G 2C1, Canada
FEATURES Location/Qualifiers
source 1..2384
/db_xref="H-InvDB:HIT000063204"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16p13.3"
gene 1..2384
/gene="RGS11"
5'UTR 1..77
/gene="RGS11"
CDS 78..1418
/gene="RGS11"
/note="alternative splice variant"
/codon_start=1
/product="regulator of G-protein signalling 11"
/protein_id="AAC69176.1"
/translation="MERVVVSMQDPDQGVKMRSQRLLVTVIPHAVTGSDVVQWLAQKF
CVSEEEALHLGAVLVQHGYIYPLRDPRSLMLRPDETPYRFQTPYFWTSTLRPAAELDY
AIYLAKKNIRKRGTLVDYEKDCYDRLHKKINHAWDLVLMQAREQLRAAKQRSKGDRLV
IACQEQTYWLVNRPPPGAPDVLEQGPGRGSCAASRVLMTKSADFHKREIEYFRKALGR
TRVKSSVCLEAYLSFCGQRGPHDPLVSGCLPSNPWISDNDAYWVMNAPTVAAPTKLRV
ERWGFSFRELLEDPVGRAHFMDFLGKEFSGENLSFWEACEELRYGAQAQVPTLVDAVY
EQFLAPGAAHWVNIDSRTMEQTLEGLRQPHRYVLDDAQLHIYMLMKKDSYPRFLKSDM
YKALLAEAGIPLEMKRRVFPFTWRPRHSSPSPALLPTPVEPTAACGPGGGDGVA"
misc_feature 108..353
/gene="RGS11"
/note="encodes dishevelled/Egl-10/pleckstrin (DEP) domain"
misc_feature 669..860
/gene="RGS11"
/note="encodes G-gamma-like (GGL) domain"
misc_feature 912..1256
/gene="RGS11"
/note="encodes regulator of G-protein signaling (RGS)
domain"
BASE COUNT 455 a 785 c 727 g 417 t
ORIGIN
1 gccatggccg ccggccccgc gccgcccccc ggccgccccc gggcgcagat gccgcatctg
61 aggaaggtgc gaggcggatg gagcgggtgg tcgtgagcat gcaggacccc gaccagggcg
121 tgaagatgcg gagccagcgc ctgctggtca ccgtcattcc ccacgcggtg acaggcagcg
181 acgtcgtgca gtggttggcc cagaagttct gcgtctcgga ggaggaggcc ctgcacctgg
241 gcgccgtcct ggtgcagcat ggctacatct acccgctgcg cgacccccgt agcctcatgc
301 tccggccaga cgagacgccc tacaggttcc agaccccgta cttctggaca agtaccctga
361 ggccggctgc agagctggac tatgccatct acctggccaa gaagaacatc cgaaaacggg
421 ggaccctggt ggattatgag aaggactgct atgaccggct acacaagaag atcaaccacg
481 catgggacct ggtgctgatg caggcgaggg agcagctgag ggcagccaag cagcgcagca
541 agggggacag gctggtcatt gcgtgccagg agcagaccta ctggctggtg aacaggcccc
601 cgcccggggc ccccgatgtg ctggagcagg gtccagggcg gggatcctgc gctgccagcc
661 gtgtgctcat gaccaagagt gcagatttcc ataagcggga gatcgagtac ttcaggaaag
721 cgctgggcag gacccgagtg aagtcctccg tctgccttga ggcgtacctg agtttctgcg
781 gccagcgtgg accccacgat cccctcgtgt cggggtgcct gcccagcaat ccctggatct
841 cagacaatga cgcctactgg gtcatgaatg cccccacggt ggctgccccc acgaagctcc
901 gtgtggagag atggggcttc agcttccggg agctcctgga ggaccccgtg gggcgggccc
961 acttcatgga ctttctggga aaggagttca gtggagaaaa cctcagcttc tgggaggcat
1021 gtgaggagct tcgatatgga gcgcaggccc aggtccccac cctggtggat gccgtgtacg
1081 agcagttcct ggcccccgga gctgcccact gggtcaacat cgacagccgg accatggagc
1141 agaccctgga ggggctgcgc cagccccacc gctatgtcct ggatgacgcc cagctgcaca
1201 tatacatgct catgaagaag gactcctacc caaggttcct gaagtctgac atgtacaagg
1261 ccctcctggc agaggctggg atcccgctgg agatgaagag acgcgtgttc ccgtttacgt
1321 ggaggccacg gcactcgagc cccagccctg cactccttcc cacccctgtg gagcccacag
1381 cggcttgtgg ccctgggggt ggagatgggg tggcctagtg gacctggccc atctgccact
1441 ctagtccctg cagctcaacg tcctgcgtga atgcagcagc cacccccgtc ttggcccagg
1501 tcctgggggc tgctgaaccc agcaccagtg tccccttgtg cccagggggc ccagtcttct
1561 gtggggtgca cagcctccct ccctccagca agccctccct gcccagaagg aatgggtcca
1621 ggtgtggatt cccagggagg gggttcattg gctcagcttg ggtcagggca gagcctgtta
1681 cctgaagaga ggtgagacca aggccacagg gagctccacc ttctctggtc ttcagtccag
1741 cactgggtgc ccatccccat ctctaaaacc agtaaatcag ccagcgaata cccggaagca
1801 agatgcacag gcgggcggct tcccacacac ccgtcacaag acgcggacat gcaggtctcg
1861 gcgcgagctc tgccccgtcc aagagcctct ccgctgtcgc ccagtgtgag cctggaagag
1921 gacccaagag agtgccgtgc tgaggctgcc tcgaggtcac tgccttccgg agctgcgcct
1981 attcctccct cgccaaacgc gttccagaat ttgtccacag gtgcgccggc acctgctttc
2041 ccacctcgag gccgcggcct cccccccgat ttatagacaa ctctgacatt gtcaccccac
2101 tgacgaggcc cgattccata gggtggatcc ttgccaggcg tccctgatcc tccctgccca
2161 agtcttcctt cgtgagctgg ccttgctccc catcccccaa gtgcctcacc agtcccccag
2221 actgggtgaa ggtacagctg gctcctttcg ggggtgcagc ttcaactctc tcggcggtag
2281 ggcggtgcca tccccaccca tagggctggc tcacatccag tcactcccaa cagcgtccag
2341 cacacaaata aaagaccctt gggccctggc tctgagaaaa aaaa
//