LOCUS AF035153 2373 bp mRNA linear HUM 29-OCT-1998
DEFINITION Homo sapiens regulator of G-protein signalling 11 (RGS11) mRNA,
complete cds.
ACCESSION AF035153
VERSION AF035153.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2373)
AUTHORS Snow,B.E., Krumins,A.M., Brothers,G.M., Lee,S.F., Wall,M.A.,
Chung,S., Mangion,J., Arya,S., Gilman,A.G. and Siderovski,D.P.
TITLE A G protein gamma subunit-like domain shared between RGS11 and
other RGS proteins specifies binding to Gbeta5 subunits
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (22), 13307-13312 (1998)
PUBMED 9789084
REFERENCE 2 (bases 1 to 2373)
AUTHORS Snow,B.E. and Siderovski,D.P.
TITLE Direct Submission
JOURNAL Submitted (20-NOV-1997) Quantitative Biology, Amgen Institute, 620
University Avenue, Suite 706, Toronto, ON M5G 2C1, Canada
FEATURES Location/Qualifiers
source 1..2373
/db_xref="H-InvDB:HIT000063203"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16p13.3"
gene 1..2373
/gene="RGS11"
CDS 4..1407
/gene="RGS11"
/codon_start=1
/product="regulator of G-protein signalling 11"
/protein_id="AAC69175.1"
/translation="MAAGPAPPPGRPRAQMPHLRKMERVVVSMQDPDQGVKMRSQRLL
VTVIPHAVTGSDVVQWLAQKFCVSEEEALHLGAVLVQHGYIYPLRDPRSLMLRPDETP
YRFQTPYFWTSTLRPAAELDYAIYLAKKNIRKRGTLVDYEKDCYDRLHKKINHAWDLV
LMQAREQLRAAKQRSKGDRLVIACQEQTYWLVNRPPPGAPDVLEQGPGRGSCAASRVL
MTKSADFHKREIEYFRKALGRTRVKSSVCLEAYLSFCGQRGPHDPLVSGCLPSNPWIS
DNDAYWVMNAPTVAAPTKLRVERWGFSFRELLEDPVGRAHFMDFLGKEFSGENLSFWE
ACEELRYGAQAQVPTLVDAVYEQFLAPGAAHWVNIDSRTMEQTLEGLRQPHRYVLDDA
QLHIYMLMKKDSYPRFLKSDMYKALLAEAGIPLEMKRRVFPFTWRPRHSSPSPALLPT
PVEPTAACGPGGGDGVA"
misc_feature 97..342
/gene="RGS11"
/note="encodes dishevelled/Egl-10/pleckstrin (DEP) domain"
misc_feature 658..849
/gene="RGS11"
/note="encodes G-gamma-like (GGL) domain"
misc_feature 898..1245
/gene="RGS11"
/note="encodes regulator of G-protein signaling (RGS)
domain"
BASE COUNT 454 a 783 c 720 g 416 t
ORIGIN
1 gccatggccg ccggccccgc gccgcccccc ggccgccccc gggcgcagat gccgcatctg
61 aggaagatgg agcgggtggt cgtgagcatg caggaccccg accagggcgt gaagatgcgg
121 agccagcgcc tgctggtcac cgtcattccc cacgcggtga caggcagcga cgtcgtgcag
181 tggttggccc agaagttctg cgtctcggag gaggaggccc tgcacctggg cgccgtcctg
241 gtgcagcatg gctacatcta cccgctgcgc gacccccgta gcctcatgct ccggccagac
301 gagacgccct acaggttcca gaccccgtac ttctggacaa gtaccctgag gccggctgca
361 gagctggact atgccatcta cctggccaag aagaacatcc gaaaacgggg gaccctggtg
421 gattatgaga aggactgcta tgaccggcta cacaagaaga tcaaccacgc atgggacctg
481 gtgctgatgc aggcgaggga gcagctgagg gcagccaagc agcgcagcaa gggggacagg
541 ctggtcattg cgtgccagga gcagacctac tggctggtga acaggccccc gcccggggcc
601 cccgatgtgc tggagcaggg tccagggcgg ggatcctgcg ctgccagccg tgtgctcatg
661 accaagagtg cagatttcca taagcgggag atcgagtact tcaggaaagc gctgggcagg
721 acccgagtga agtcctccgt ctgccttgag gcgtacctga gtttctgcgg ccagcgtgga
781 ccccacgatc ccctcgtgtc ggggtgcctg cccagcaatc cctggatctc agacaatgac
841 gcctactggg tcatgaatgc ccccacggtg gctgccccca cgaagctccg tgtggagaga
901 tggggcttca gcttccggga gctcctggag gaccccgtgg ggcgggccca cttcatggac
961 tttctgggaa aggagttcag tggagaaaac ctcagcttct gggaggcatg tgaggagctt
1021 cgatatggag cgcaggccca ggtccccacc ctggtggatg ccgtgtacga gcagttcctg
1081 gcccccggag ctgcccactg ggtcaacatc gacagccgga ccatggagca gaccctggag
1141 gggctgcgcc agccccaccg ctatgtcctg gatgacgccc agctgcacat atacatgctc
1201 atgaagaagg actcctaccc aaggttcctg aagtctgaca tgtacaaggc cctcctggca
1261 gaggctggga tcccgctgga gatgaagaga cgcgtgttcc cgtttacgtg gaggccacgg
1321 cactcgagcc ccagccctgc actccttccc acccctgtgg agcccacagc ggcttgtggc
1381 cctgggggtg gagatggggt ggcctagtgg acctggccca tctgccactc tagtccctgc
1441 agctcaacgt cctgcgtgaa tgcagcagcc acccccgtct tggcccaggt cctgggggct
1501 gctgaaccca gcaccagtgt ccccttgtgc ccagggggcc cagtcttctg tggggtgcac
1561 agcctccctc cctccagcaa gccctccctg cccagaagga atgggtccag gtgtggattc
1621 ccagggaggg ggttcattgg ctcagcttgg gtcagggcag agcctgttac ctgaagagag
1681 gtgagaccaa ggccacaggg agctccacct tctctggtct tcagtccagc actgggtgcc
1741 catccccatc tctaaaacca gtaaatcagc cagcgaatac ccggaagcaa gatgcacagg
1801 cgggcggctt cccacacacc cgtcacaaga cgcggacatg caggtctcgg cgcgagctct
1861 gccccgtcca agagcctctc cgctgtcgcc cagtgtgagc ctggaagagg acccaagaga
1921 gtgccgtgct gaggctgcct cgaggtcact gccttccgga gctgcgccta ttcctccctc
1981 gccaaacgcg ttccagaatt tgtccacagg tgcgccggca cctgctttcc cacctcgagg
2041 ccgcggcctc ccccccgatt tatagacaac tctgacattg tcaccccact gacgaggccc
2101 gattccatag ggtggatcct tgccaggcgt ccctgatcct ccctgcccaa gtcttccttc
2161 gtgagctggc cttgctcccc atcccccaag tgcctcacca gtcccccaga ctgggtgaag
2221 gtacagctgg ctcctttcgg gggtgcagct tcaactctct cggcggtagg gcggtgccat
2281 ccccacccat agggctggct cacatccagt cactcccaac agcgtccagc acacaaataa
2341 aagacccttg ggccctggct ctgagaaaaa aaa
//