LOCUS AF035119 3821 bp mRNA linear HUM 23-DEC-2016
DEFINITION Homo sapiens deleted in liver cancer-1 (DLC-1) mRNA, complete cds.
ACCESSION AF035119
VERSION AF035119.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3821)
AUTHORS Yuan,B.Z., Miller,M.J., Keck,C.L., Zimonjic,D.B., Thorgeirsson,S.S.
and Popescu,N.C.
TITLE Direct Submission
JOURNAL Submitted (19-NOV-1997) Laboratory of Experimental Carcinogenesis,
National Cancer Institute, 9000 Rockville Pike, Bethesda, MD 20892,
USA
REFERENCE 2 (bases 1 to 3821)
AUTHORS Yuan,B.Z., Miller,M.J., Keck,C.L., Zimonjic,D.B., Thorgeirsson,S.S.
and Popescu,N.C.
TITLE Direct Submission
JOURNAL Submitted (23-DEC-2016) Laboratory of Experimental Carcinogenesis,
National Cancer Institute, 9000 Rockville Pike, Bethesda, MD 20892,
USA
REMARK Sequence update by database staff to remove vector contamination
COMMENT On Dec 23, 2016 this sequence version replaced AF035119.1.
FEATURES Location/Qualifiers
source 1..3821
/db_xref="H-InvDB:HIT000063200"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8p21-p22"
gene 1..3821
/gene="DLC-1"
CDS 296..3571
/gene="DLC-1"
/note="similar to Rattus rattus RhoGAP encoded by the
sequence presented in GenBank Accession Number D31962"
/codon_start=1
/product="deleted in liver cancer-1"
/protein_id="AAB87700.1"
/translation="MCRKKPDTMILTQIEAKEACDWLRATGFPQYAQLYEDFLFPIDI
SLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSDDSDEDEPCAISGKWT
FQRDSKRWSRLEEFDVFSPKQDLVPGSPDDSHPKDGPSPGGTLMDLSERQEVSSVRSL
SSTGSLPSHAPPSEDAATPRTNSVISVCSSSNLAGNDDSFGSLPSPKELSSFSFSMKG
HEKTAKSKTRSLLKRMESLKLKSSHHSKHKAPSKLGLIISGPILQEGMDEEKLKQLSC
VEISALNGNRINVPMVRKRSVSNSTQTSSSSSQSETSSAVSTPSPVTRTRSLSACNKR
VGMYLEGFDPFNQSTFNNVVEQNFKNRESYPEDTVFYIPEDHKPGTFPKALTNGSFSP
SGNNGSVNWRTGSFHGPGHISLRRENSSDSPKELKRRNSSSSMSSRLSIYDNVPGSIL
YSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEKFSDEGDSDSALDSVSPCPS
SPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEPSEIPERRDSGVGASLTRSNRHRLRWH
SFQSSHRPSLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKF
MKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFKKSGVK
SRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYV
PKDQRLQAIKAAIMLLPDENRVVLQTLLYFLCDVTAAVKENQMTPTNLAVCLAPSLFH
LNTLKRENSSPRVMQRKQSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRC
RNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTSEQ
AELSYKKVSEGPRLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQT
EIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVGVRVNVLLSR
YLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDT
KSR"
BASE COUNT 1001 a 1054 c 982 g 784 t
ORIGIN
1 gcccgagcga gggcgcttcg ctcccagcca ggacatggcc gcacctctcc gcatcaggag
61 cgccggctca cggacttctc gcccaactcc ctgagcgctc cctcgtttcg atctttagaa
121 aaccccgctt tctttctggg gccgtgacga ggggcaggga gcggcgagca aggatgcgtt
181 gaggaccgcg agggcgcgcg tctcgggtgc cgccgtgggt cccgacgcgg aagccgagcc
241 gcctccgcct gcctcgactt ccccacagcg cttccgccgc cgcctgccgt gcttgatgtg
301 cagaaagaag ccggacacca tgatcctaac acaaattgaa gccaaggaag cttgtgattg
361 gctacgggca actggtttcc cccagtatgc acagctttat gaagatttcc tgttccccat
421 cgatatttcc ttggtcaaga gagagcatga ttttttggac agagatgcca ttgaggctct
481 atgcaggcgt ctaaatactt taaacaaatg tgcggtgatg aagctagaaa ttagtcctca
541 tcggaaacga agtgacgatt cagacgagga tgagccttgt gccatcagtg gcaaatggac
601 tttccaaagg gacagcaaga ggtggtcccg gcttgaagag tttgatgtct tttctccaaa
661 acaagacctg gtccctgggt ccccagacga ctcccacccg aaggacggcc ccagccccgg
721 aggcacgctg atggacctca gcgagcgcca ggaggtgtct tccgtccgca gcctcagcag
781 cactggcagc ctccccagcc acgcgccccc cagcgaggat gctgccaccc cccggactaa
841 ctccgtcatc agcgtttgct cctccagcaa cttggcaggc aatgacgact ctttcggcag
901 cctgccctct cccaaggaac tgtccagctt cagcttcagc atgaaaggcc acgaaaaaac
961 tgccaagtcc aagacgcgca gtctgctgaa acggatggag agcctgaagc tcaagagctc
1021 ccatcacagc aagcacaaag cgccctcaaa gctggggttg atcatcagcg ggcccatctt
1081 gcaagagggg atggatgagg agaagctgaa gcagctcagc tgcgtggaga tctccgccct
1141 caatggcaac cgcatcaacg tccccatggt acgaaagagg agcgtttcca actccacgca
1201 gaccagcagc agcagcagcc agtcggagac cagcagcgcg gtcagcacgc ccagccctgt
1261 tacgaggacc cggagcctca gtgcgtgcaa caagcgggtg ggcatgtact tagagggctt
1321 cgatcctttc aatcagtcaa catttaacaa cgtggtggag cagaacttta agaaccgcga
1381 gagctaccca gaggacacgg tgttctacat ccctgaagat cacaagcctg gcactttccc
1441 caaagctctc accaatggca gtttctcccc ctcggggaat aacggctctg tgaactggag
1501 gacgggaagc ttccacggcc ctggccacat cagcctcagg agggaaaaca gtagcgacag
1561 ccccaaggaa ctgaagagac gcaattcttc cagctccatg agcagccgcc tgagcatcta
1621 cgacaacgtg ccgggctcca tcctctactc cagttcaggg gacctggcgg atctggagaa
1681 cgaggacatc ttccccgagc tggacgacat cctctaccac gtgaagggga tgcagcggat
1741 agtcaatcag tggtcggaga agttttctga tgagggagat tcggactcag ccctggactc
1801 ggtctctccc tgcccgtcct ctccaaaaca gatacacctg gatgtggaca acgaccgaac
1861 cacacccagc gacctggaca gcacaggcaa ctccctgaat gaaccggaag agccctccga
1921 gatcccggaa agaagggatt ctggggttgg ggcttcccta accaggtcca acaggcaccg
1981 actgagatgg cacagtttcc agagctcaca tcggccaagc ctcaactctg tatcactaca
2041 gattaactgc cagtctgtgg cccagatgaa cctgctgcag aaatactcac tcctaaagct
2101 aacggccctg ctggagaaat acacaccttc taacaagcat ggttttagct gggccgtgcc
2161 caagttcatg aagaggatca aggttccaga ctacaaggac cggagtgtgt ttggggtccc
2221 actgacggtc aacgtgcagc gcacaggaca accgttgcct cagagcatcc agcaggccat
2281 gcgatacctc cggaaccatt gtttggatca ggttgggctc ttcaaaaaat cgggggtcaa
2341 gtcccggatt caggctctgc gccagatgaa tgaaggtgcc atagactgtg tcaactacga
2401 aggacagtct gcttatgacg tggcagacat gctgaagcag tattttcgag atcttcctga
2461 gccactaatg acgaacaaac tctcggaaac ctttctacag atctaccaat atgtgcccaa
2521 ggaccagcgc ctgcaggcca tcaaggctgc catcatgctg ctgcctgacg agaaccgggt
2581 ggttctgcag accctgcttt atttcctgtg cgatgtcaca gcagccgtaa aagaaaacca
2641 gatgacccca accaacctgg ccgtgtgctt agcgccttcc ctcttccatc tcaacaccct
2701 gaagagagag aattcctctc ccagggtaat gcaaagaaaa caaagtttgg gcaaaccaga
2761 tcagaaagat ttgaatgaaa acctagctgc cactcaaggg ctggcccata tgatcgccga
2821 gtgcaagaag cttttccagg ttcccgagga aatgagccga tgtcgtaatt cctataccga
2881 acaagagctg aagcccctca ctctggaagc actcgggcac ctgggtaatg atgactcagc
2941 tgactaccaa cacttcctcc aggactgtgt ggatggcctg tttaaagaag tcaaagagaa
3001 gtttaaaggc tgggtcagct actccacttc ggagcaggct gagctgtcct ataagaaggt
3061 gagcgaagga ccccgtctga ggctttggag gtcagtcatt gaagtccctg ctgtgccaga
3121 ggaaatctta aagcgcctac ttaaagaaca gcacctctgg gatgtagacc tgttggattc
3181 aaaagtgatc gaaattctgg acagccaaac tgaaatttac cagtatgtcc aaaacagtat
3241 ggcacctcat cctgctcgag actacgttgt tttaagaacc tggaggacta atttacccaa
3301 aggagcctgt gcccttttac taacctctgt ggatcacgat cgcgcacctg tggtgggtgt
3361 gagggttaat gtgctcttgt ccaggtattt gattgaaccc tgtgggccag gaaaatccaa
3421 actcacctac atgtgcagag ttgacttaag gggccacatg ccagaatggt acacaaaatc
3481 ttttggacat ttgtgtgcag ctgaagttgt aaagatccgg gattccttca gtaaccagaa
3541 cactgaaacc aaagacacca aatctaggtg atcactgaag caacgcaacc gcttccacca
3601 ccatggtgtt tgtttttaga agttttgcca gtccttgaag aatgggttct gtgtgtaatc
3661 ctgaaacaaa gaaaactaca agctggagtg taggaattga ctatagcaat ttgatacatt
3721 tttaaagctg cttcctgttt gttgagggtc tgtattcata gaccttgact ggaatatgta
3781 agactgtgcg aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//