LOCUS AF034840 2809 bp mRNA linear HUM 05-SEP-2007
DEFINITION Homo sapiens E-type ATPase (HB6) mRNA, complete cds.
ACCESSION AF034840
VERSION AF034840.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2809)
AUTHORS Smith,T.M. and Kirley,T.L.
TITLE Cloning, sequencing, and expression of a human brain ecto-apyrase
related to both the ecto-ATPases and CD39 ecto-apyrases1
JOURNAL Biochim. Biophys. Acta 1386 (1), 65-78 (1998)
PUBMED 9675246
REFERENCE 2 (bases 1 to 2809)
AUTHORS Munkonda,M.N., Kauffenstein,G., Kukulski,F., Levesque,S.A.,
Legendre,C., Pelletier,J., Lavoie,E.G., Lecka,J. and Sevigny,J.
TITLE Inhibition of human and mouse plasma membrane bound NTPDases by P2
receptor antagonists
JOURNAL Biochem. Pharmacol. 74 (10), 1524-1534 (2007)
PUBMED 17727821
REFERENCE 3 (bases 1 to 2809)
AUTHORS Smith,T.M. and Kirley,T.L.
TITLE Direct Submission
JOURNAL Submitted (17-NOV-1997) Pharmacology and Cell Biophysics,
University of Cincinnati, 231 Bethesda Avenue, Cincinnati, OH
45267-0575, USA
REFERENCE 4 (bases 1 to 2809)
AUTHORS Smith,T.M. and Kirley,T.L.
TITLE Direct Submission
JOURNAL Submitted (27-APR-2001) Pharmacology and Cell Biophysics,
University of Cincinnati, 231 Bethesda Avenue, Cincinnati, OH
45267-0575, USA
REMARK Sequence update by submitter
COMMENT On Apr 27, 2001 this sequence version replaced AF034840.1.
FEATURES Location/Qualifiers
source 1..2809
/db_xref="H-InvDB:HIT000063166"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/sex="female"
/tissue_type="brain"
/dev_stage="adult (36 year old)"
/note="Caucasian"
gene 1..2809
/gene="HB6"
CDS 80..1669
/gene="HB6"
/note="cell membrane ecto-nucleoside di- and
tri-phosphatase (ecto-ATP-diphosphohydrolase); putative
ancestor of both ecto-ATPases and CD39 ecto-apyrases"
/codon_start=1
/product="E-type ATPase"
/protein_id="AAC09236.2"
/translation="MFTVLTRQPCEQAGLKALYRTPTIIALVVLLVSIVVLVSITVIQ
IHKQEVLPPGLKYGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFKCSVKGSGISSY
GNNPQDVPRAFEECMQKVKGQVPSHLHGSTPIHLGATAGMRLLRLQNETAANEVLESI
QSYFKSQPFDFRGAQIISGQEEGVYGWITANYLMGNFLEKNLWHMWVHPHGVETTGAL
DLGGASTQISFVAGEKMDLNTSDIMQVSLYGYVYTLYTHSFQCYGRNEAEKKFLAMLL
QNSPTKNHLTNPCYPRDYSISFTMGHVFDSLCTVDQRPESYNPNDVITFEGTGDPSLC
KEKVASIFDFKACHDQETCSFDGVYQPKIKGPFVAFAGFYYTASALNLSGSFSLDTFN
SSTWNFCSQNWSQLPLLLPKFDEVYARSYCFSANYIYHLFVNGYKFTEETWPQIHFEK
EVGNSSIAWSLGYMLSLTNQIPAESPLIRLPIEPPVFVGTLAFFTAAALLCLAFLAYL
CSATRRKRHSEHAFDHAVDSD"
BASE COUNT 773 a 696 c 610 g 730 t
ORIGIN
1 ccttagcgct ggccgcggcg gcctctgcgg cagcgctagt cgccttctcc gaatcggctc
61 cgcacagcta ggagaaaaga tgttcactgt gctgacccgc caaccatgtg agcaagcagg
121 cctcaaggcc ctctaccgaa ctccaaccat cattgccttg gtggtcttgc ttgtgagtat
181 tgtggtactt gtgagtatca ctgtcatcca gatccacaag caagaggtcc tccctccagg
241 actgaagtat ggtattgtgc tggatgccgg gtcttcaaga accacagtct acgtgtatca
301 atggccagca gaaaaagaga ataataccgg agtggtcagt caaaccttca aatgtagtgt
361 gaaaggctct ggaatctcca gctatggaaa taacccccaa gatgtcccca gagcctttga
421 ggagtgtatg caaaaagtca aggggcaggt tccatcccac ctccacggat ccacccccat
481 tcacctggga gccacggctg ggatgcgctt gctgaggttg caaaatgaaa cagcagctaa
541 tgaagtcctt gaaagcatcc aaagctactt caagtcccag ccctttgact ttaggggtgc
601 tcaaatcatt tctgggcaag aagaaggggt atatggatgg attacagcca actatttaat
661 gggaaatttc ctggagaaga acctgtggca catgtgggtg cacccgcatg gagtggaaac
721 cacgggtgcc ctggacttag gtggtgcctc cacccaaata tccttcgtgg caggagagaa
781 gatggatctg aacaccagcg acatcatgca ggtgtccctg tatggctacg tatacacgct
841 ctacacacac agcttccagt gctatggccg gaatgaggct gagaagaagt ttctggcaat
901 gctcctgcag aattctccta ccaaaaacca tctcaccaat ccctgttacc ctcgggatta
961 tagcatcagc ttcaccatgg gccatgtatt tgatagcctg tgcactgtgg accagaggcc
1021 agaaagttat aaccccaatg atgtcatcac ttttgaagga actggggacc catctctgtg
1081 taaggagaag gtggcttcca tatttgactt caaagcttgc catgatcaag aaacctgttc
1141 ttttgatggg gtttatcagc caaagattaa agggccattt gtggcttttg caggattcta
1201 ctacacagcc agtgctttaa atctttcagg tagcttttcc ctggacacct tcaactccag
1261 cacctggaat ttctgctcac agaattggag tcagctccca ctgctgctcc ccaaatttga
1321 tgaggtatat gcccgctctt actgcttctc agccaactac atctaccact tgtttgtgaa
1381 cggttacaaa ttcacagagg agacttggcc ccaaatacac tttgaaaaag aagtggggaa
1441 tagcagcata gcctggtctc ttggctacat gctcagcctg accaaccaga tcccagctga
1501 aagccctctg atccgtctgc ccatagaacc acctgtcttt gtgggcaccc tcgctttctt
1561 cacagcggca gccttgctgt gtctggcatt tcttgcatac ctgtgttcag caaccagaag
1621 aaagaggcac tccgagcatg cctttgacca tgcagtggat tctgactgag ccttcaaagc
1681 agctcctgga gtccaatggc tgcttagagt cagcctgggt ggcaccaggc aatgcaggtg
1741 aagtggctgc cttcaggaaa tacaactaac taaaatcaaa cacctaggtc acgtgcctct
1801 caaatactga tttctgccac agcacctctt gaggcatccc ttggctattc tgtgcatatt
1861 gttcttcaga gacctcacta cccacatgct gatctattgg ggaacagaga agagacaggc
1921 cacgaaggtc aggctcttta tattaagttc cccagaggaa gagtaagttg agaaggtatc
1981 agtttaatgt tgaagaattg acctcagggc tcagtttcca tttccctccc tcagtattct
2041 tcctggcaag atacccatta agcatttcgc caatcagaat ctcattttat agtttttccc
2101 attggtcttt aactaagact ttcttgtagc aatctcgtaa gcagtgaacc ccctcagatc
2161 agtagatata gtatctgggg gagaagactt acttccttca gggcagcagc cacagccagg
2221 cttctgtcat acaggtagat cccgaagcac agagacataa aaaaggtctc ccagaaaagt
2281 atagaccatt ctccaagtgg aattcccact tagggctctg gtcactagat tgcaacctgt
2341 gtgtttgtca tcatcctcat ctcaccattg tattgctatg ccctcccata aaaacacatt
2401 gatccctagc aagattattg cattccagat tttactgcct ttgctaggct tttgcttagc
2461 aaagggctga ctttccattg ttatcatggt gtatatattt tgtcaccatt cccacaagta
2521 tacttgatgt tgtcatagaa cgaacatcct actctatgat ttactaacca attactttcc
2581 cagatcatag acctctctgc atagtagtca taggtcttga ctttggggaa agaaaaggaa
2641 gctgcaggaa tatttatctc caaagtcgaa tgagaaagaa ctccagcaaa tccaatggct
2701 acaaactaaa aatcagcatt atttcatatt gctgtttctt agctgaatat ggaataaaga
2761 actattattt tattttgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//