LOCUS AF032906 1541 bp mRNA linear HUM 19-FEB-2004
DEFINITION Homo sapiens cathepsin Z precursor (CTSZ) mRNA, complete cds.
ACCESSION AF032906
VERSION AF032906.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1541)
AUTHORS Santamaria,I., Velasco,G., Pendas,A.M., Fueyo,A. and Lopez-Otin,C.
TITLE Cathepsin Z, a novel human cysteine proteinase with a short
propeptide domain and a unique chromosomal location
JOURNAL J. Biol. Chem. 273 (27), 16816-16823 (1998)
PUBMED 9642240
REFERENCE 2 (bases 1 to 1541)
AUTHORS Santamaria,I. and Lopez-Otin,C.
TITLE Direct Submission
JOURNAL Submitted (04-NOV-1997) Dept. Bioquimica, Facultad de Medicina,
Julian Claveria 6, Oviedo 33006, Spain
FEATURES Location/Qualifiers
source 1..1541
/db_xref="H-InvDB:HIT000063112"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="prostate"
gene 1..1541
/gene="CTSZ"
5'UTR 1..240
/gene="CTSZ"
CDS 241..1152
/gene="CTSZ"
/codon_start=1
/product="cathepsin Z precursor"
/protein_id="AAC39839.1"
/translation="MARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAP
LGRTTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMA
DRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAK
DQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMA
TERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIV
TSTYKDGKGARYNLAIEEHCTFGDPIV"
sig_peptide 241..300
/gene="CTSZ"
misc_feature 301..1149
/gene="CTSZ"
/note="encodes cathepsin Z proprotein"
mat_peptide 424..1149
/gene="CTSZ"
/product="cathepsin Z"
3'UTR 1153..1541
/gene="CTSZ"
BASE COUNT 374 a 384 c 511 g 272 t
ORIGIN
1 aaatggtgaa agggggggag gggagaaaag aaaaaaaaaa aaagaaaggg gaaagggggg
61 aaaaataaga aaaagcgaga cagaggcgct gccgcgtccg ctcgcgggga aggctggggt
121 cggccgggtg ctaggccggg gccgaggccg aggccggggc gggatccaga gcgggagccg
181 gcgcgggatc tgggactcgg agcgggatcc ggagcgggac ccaggagccg gcgcggggcc
241 atggcgaggc gcgggccagg gtggcggccg cttctgctgc tcgtgctgct ggcgggcgcg
301 gcgcagggcg gcctctactt ccgccgggga cagacctgct accggcctct gcggggggac
361 gggctggctc cgctggggcg cacgacatac ccccggcctc atgagtacct gtccccagcg
421 gatctgccca agagctggga ctggcgcaat gtggatggtg tcaactatgc cagcatcacc
481 cggaaccagc acatccccca atactgcggc tcctgctggg cccacgccag caccagcgct
541 atggcggatc ggatcaacat caagaggaag ggagcgtggc cctccaccct cctgtccgtg
601 cagaacgtca tcgactgcgg taacgctggc tcctgtgaag ggggtaatga cctgtccgtg
661 tgggactacg cccaccagca cggcatccct gacgagacct gcaacaacta ccaggccaag
721 gaccaggagt gtgacaagtt taaccaatgt gggacatgca atgaattcaa agagtgccac
781 gccatccgga actacaccct ctggagggtg ggagactacg gctccctctc tgggagggag
841 aagatgatgg cagaaatcta cgcaaatggt cccatcagct gtggaataat ggcaacagaa
901 agactggcta actacaccgg aggcatctat gccgaatacc aggacaccac atatataaac
961 catgtcgttt ccgtggctgg gtggggcatc agtgatggga ctgagtactg gattgtccgg
1021 aattcatggg gtgaaccatg gggcgagaga ggctggctga ggatcgtgac cagcacctat
1081 aaggatggga agggcgccag atacaacctt gccatcgagg agcactgtac atttggggac
1141 cccatcgttt aaggccatgt cactagaagc gcagtttaag aaaaggcatg gtgacccatg
1201 accagagggg atcctatggt tatgtgtgcc aggctggctg gcaggaactg gggtggctat
1261 caatattgga tggcgaggac agcgtggtac tggctgcgag tgttcctgag agttgaaagt
1321 gggatgactt atgacacttg cacagcatgc tctgcctcac aatgatgcag tcagccacct
1381 ggtgaagaag tgacctgcaa cacaggaaac gatgggacct cagtcttctt cagcagagga
1441 cttgatattt tgtatttggc aactgtgggc aataatatgg catttaagag gtgaaagagt
1501 tcagacttat caccattctt atgtcacttt agaatcaagg g
//