LOCUS AF032897 4113 bp mRNA linear HUM 04-AUG-2000
DEFINITION Homo sapiens potassium channel subunit (HERG-3) mRNA, complete cds.
ACCESSION AF032897
VERSION AF032897.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4113)
AUTHORS Ganetzky,B. and Titus,S.A.
TITLE Polynucleotides encoding herg-3 potassium channel
JOURNAL Patent: US 5,986,081 16-NOV-1999;
Wisconsin Alumni Research Foundation; Madison, WI;
USA;
REFERENCE 2 (bases 1 to 4113)
AUTHORS Titus,S.A. and Ganetzky,B.S.
TITLE Direct Submission
JOURNAL Submitted (03-NOV-1997) Genetics, UW-Madison, 445 Henry Mall,
Madison, WI 53706, USA
FEATURES Location/Qualifiers
source 1..4113
/db_xref="H-InvDB:HIT000063110"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
gene 1..4113
/gene="HERG-3"
CDS 101..3691
/gene="HERG-3"
/codon_start=1
/product="potassium channel subunit"
/protein_id="AAD01946.1"
/translation="MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYC
NDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKN
GSTFICNTHIIPVKNQEGVAMMFIINFEYVTDNENAATPERVNPILPIKTVNRKFFGF
KFPGLRVLTYRKQSLPQEDPDVVVIDSSKHSDDSVAMKHFKSPTKESCSPSEADDTKA
LIQPSKCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSV
HDIEGFGVHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQ
LTLNFSEVKTEKKNSSPPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQT
PRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSP
LNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFD
LLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLSMCIFALNAHWL
ACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSS
LTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLR
VKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLL
QNCKAFRGASKGCLRALAMKFKTTHALQGDTLVHCGDVLTALYFLSRGSIEISKNDMV
VAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFL
TNLELTFNLRHESAKADLLRSQSMNDSEGDNCKLRRRKLSFESEGEKENSTNDPEDSA
DTIRHYQSSKRHFEEKKSRSSSFISSIDDEQKPLFSGIVDSSPGIGKASGLDFEETVP
TSGRMHIDKRSHSCKDITDMRSWERENAHPQPEDSSPSALQRAAWGISETESDLTYGE
VEQRLDLLQEQLNRLESQMTTDIQTILQLLQKQTTVVPPAYSMVTAGSEYQRPIIQLM
RTSQPEASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGVHLNTASEDNLTSLLKQ
DSDLSLELHLRQRKTYVHPIRHPSLPDSSLSTVGIVGLHRHVSDPGLPGK"
BASE COUNT 1265 a 937 c 840 g 1071 t
ORIGIN
1 caaagagcgg ctcgcgcgct ggcctgggct ctaaccgagg agagatcccg ggagaactcc
61 agagctccgg gggagcgctc ctcggaagac cggggccaac atgcctgtgc gcagggggca
121 tgtggcacca caaaatacat ttctggggac catcattcgg aaatttgaag ggcaaaataa
181 aaaatttatc attgcaaatg ccagagtgca gaactgtgcc atcatttatt gcaacgatgg
241 gttctgtgag atgactggtt tctccaggcc agatgtcatg caaaagccat gcacctgcga
301 ctttctccat ggacccgaga ccaagaggca tgatattgcc caaattgccc aggcattgct
361 ggggtcagaa gagaggaaag tggaggtcac ctactatcac aaaaatgggt ccacttttat
421 ttgtaacact cacataattc cagtgaaaaa ccaagagggc gtggctatga tgttcatcat
481 taattttgaa tatgtgacgg ataatgaaaa cgctgccacc ccagagaggg taaacccaat
541 attaccaatc aaaactgtaa accggaaatt ttttgggttc aaattccctg gtctgagagt
601 tctcacttac agaaagcagt ccttaccaca agaagacccc gatgtggtgg tcatcgattc
661 atctaaacac agtgatgatt cagtagccat gaagcatttt aagtctccta caaaagaaag
721 ctgcagcccc tctgaagcag atgacacaaa agctttgata cagcccagca aatgttctcc
781 cttggtgaat atatccggac ctcttgacca ttcctctccc aaaaggcaat gggaccgact
841 ctaccctgac atgctgcagt caagttccca gctgtcccat tccagatcaa gggaaagctt
901 atgtagtata cggagagcat cttcggtcca tgatatagaa ggattcggcg tccaccccaa
961 gaacatattt agagaccgac atgccagcga agacaatggt cgcaatgtca aagggccttt
1021 taatcatatc aagtcaagcc tcctgggatc cacatcagat tcaaacctca acaaatacag
1081 caccattaac aagattccac agctcactct gaatttttca gaggtcaaaa ctgagaaaaa
1141 gaattcatca cctccttctt cagataaaac cattattgca cccaaggtta aagatcgaac
1201 acacaatgtg actgagaaag tgacccaggt tctctcttta ggagcagatg tcctacctga
1261 atacaaactg cagacaccac gcatcaacaa gtttacgata ttgcactaca gccctttcaa
1321 ggcagtctgg gactggctta tcctgctgtt ggtcatatac actgctatat ttactcccta
1381 ctctgcagcc ttcctcctca atgacagaga agaacagaag agacgagaat gtggctattc
1441 ttgtagccct ttgaatgtgg tagacttgat tgtggatatt atgtttatca tagatatttt
1501 aataaacttc agaacaacat atgttaatca gaatgaagaa gtggtaagtg atcccgccaa
1561 aatagcaata cactacttca aaggctggtt cctgattgac atggttgcag caattccttt
1621 tgacttgctg atttttggat caggttctga tgagacaaca acattaattg gtcttttgaa
1681 gactgcccga ctcctccgtc ttgtgcgcgt ggccaggaaa ctggatcgat attcagaata
1741 tggcgctgct gttctaatgc tctcaatgtg catctttgcc ctgaatgcac actggctggc
1801 ttgcatttgg tatgcgattg ggaatgtaga aaggccttac ctgactgaca aaatcggatg
1861 gttggattcc ttaggacagc aaattgggaa acgttacaat gacagtgact caagttctgg
1921 accatccatt aaagacaaat acgtcacagc actttatttt accttcagca gtttaaccag
1981 tgtaggattc gggaatgtgt ctcctaacac gaattcggag aaaatctttt caatttgtgt
2041 catgttgatt ggctcactaa tgtatgcaag catttttggg aatgtatctg caattatcca
2101 aagactatac tcgggaactg ccaggtacca catgcagatg ctgcgagtaa aagagttcat
2161 tcgctttcac caaatcccca accctctgag gcaacgtctt gaagaatatt tccagcacgc
2221 atggacttac accaatggca ttgacatgaa catggtccta aagggtttcc cagaatgctt
2281 acaagcagac atttgtctac atctcaacca gacattgctg caaaactgca aagcctttcg
2341 gggggcaagt aaaggttgcc ttagagcttt ggcaatgaag ttcaaaacca cccatgcact
2401 ccaaggagac accctcgttc actgtgggga tgtcctcact gcactttatt tcttatccag
2461 aggctccatt gaaatctcaa agaatgacat ggtggtggct attctgggaa aaaatgatat
2521 atttggagaa atggttcatc tttatgccaa acctggaaag tctaatgcag atgtaagagc
2581 cctcacatac tgtgacttgc ataagattca gcgagaagac ttgttagagg ttttggatat
2641 gtatcctgag ttttctgatc actttctaac aaacctagag ttgactttca acctaaggca
2701 tgagagcgca aaggctgatc tcctacgatc acaatccatg aatgattcag aaggagacaa
2761 ctgtaaacta agaagaagga aattgtcatt tgaaagtgaa ggagagaaag aaaacagtac
2821 aaatgatcct gaagactctg cagataccat aagacattat cagagttcca agagacactt
2881 tgaagagaaa aaaagcagat cctcatcttt catctcctcc attgatgatg aacaaaagcc
2941 gctcttctca ggaatagtag actcttctcc aggaataggg aaagcatctg ggctcgattt
3001 tgaagaaaca gtgcccacct caggaagaat gcacatagat aaaagaagtc actcttgcaa
3061 agatatcact gacatgcgaa gctgggaacg agaaaatgca catccccagc ctgaagactc
3121 cagtccatct gcacttcagc gagctgcctg gggtatctct gaaaccgaaa gcgacctcac
3181 ctacggggaa gtggaacaaa gattagatct gctccaggag caacttaaca ggcttgaatc
3241 ccaaatgacc actgacatcc agaccatctt acagttgctg cagaaacaaa ccactgtggt
3301 ccccccagcc tacagtatgg taacagcagg atcagaatat cagagaccca tcatccagct
3361 gatgagaacc agtcaaccgg aagcatccat caaaactgac cgaagtttca gcccttcctc
3421 acaatgtcct gaatttctag accttgaaaa atctaaactt aaatccaaag aatccctttc
3481 aagtggggtg catctgaaca cagcttcaga agacaacttg acttcacttt taaaacaaga
3541 cagtgatctc tctttagagc ttcacctgcg gcaaagaaaa acttacgttc atccaattag
3601 gcatccttct ttgccagatt catccctaag cactgtagga atcgtgggtc ttcataggca
3661 tgtttctgat cctggtcttc cagggaaata atcattttgt actatttact ccacatacaa
3721 tgtaagtgct tttaatggct gttttccttt ttctatttaa atcctctcta cttgactcag
3781 gggctcacaa ggtaccatta tatgcaaaag tactgtatat tttcctaaat tgaagcttgt
3841 aaggtaaaac tgagcagtta ggatgtaaat atacataaga acttttggtt ccaaatgtta
3901 aaactgccag catctcacgg caccttattt tttattttta ttttttaaat cacatgcatg
3961 ttaggaaact ccaatttctc ttgcatggag actcctattt actgctttta ctaaaccagt
4021 acttcgttat gaaaatgcct tccacgcaaa taagaaacca agggataaaa ctgttcatgg
4081 atgcaactca aattcagatg atcatcaagg cat
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