LOCUS AF032119 3122 bp mRNA linear HUM 27-OCT-2000
DEFINITION Homo sapiens hCASK (CASK) mRNA, complete cds.
ACCESSION AF032119
VERSION AF032119.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3122)
AUTHORS Cohen,A.R., Woods,D.F., Marfatia,S.M., Walther,Z., Chishti,A.H.,
Anderson,J.M. and Wood,D.F.
TITLE Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to
the basolateral membrane of epithelial cells
JOURNAL J. Cell Biol. 142 (1), 129-138 (1998)
PUBMED 9660868
REFERENCE 2 (bases 1 to 3122)
AUTHORS Cohen,A.R., Woods,D.F. and Anderson,J.M.
TITLE Direct Submission
JOURNAL Submitted (31-OCT-1997) Cell Biology, Yale University, 333 Cedar
Street, P.O. Box 208019, New Haven, CT 06520-8019, USA
FEATURES Location/Qualifiers
source 1..3122
/db_xref="H-InvDB:HIT000063087"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="liver, lung, and brain"
gene 1..3122
/gene="CASK"
/note="similar to C. elegans lin-2, Drosophila camguk and
rat cask"
CDS 28..2793
/gene="CASK"
/note="membrane associated guanylate kinase; CASK/LIN-2;
CAMGUK"
/codon_start=1
/product="hCASK"
/protein_id="AAB88125.1"
/translation="MADDDVLFEDVYELCEVIGKGPFSVVRRCINRETGQQFAVKIVD
VAKFTSSPGLSTEDLKREASICHMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFE
IVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKL
GGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLP
FYGTKERLFEGIIKGKYKMNPRQWSHISESAKDLVRRMLMLDPAERITVYEALNHPWL
KERDRYAYKIHLPETVEQLRKFNARRKLKGAVLAAVSSHKFNSFYGDPPEELPDFSED
PTSSGLLAAERAVSQVLDSLEEIHALTDCSEKDLDFLHSVFQDQHLHTLLDLYDKINT
KSSPQIRNPPSDAVQRAKEVLEEISCYPENNDAKELKRILTQPHFMALLQTHDVVAHE
VYSDEALRVTPPPTSPYLNGDSPESANGGMDMENVTRVRLVQFQKNTDEPMGITLKMN
ELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFK
IVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYD
PAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSSELQEWRV
ACIAMEKTKQEQQASCTWFGKKKKQYKDKYLAKHNADLVTYEEVVKLPAFKRKTLVLL
GAHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKRDEENGKNYYFVSHDQMMQDISNN
EYLEYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPT
ITPGLNEDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQW
VPVSWVY"
BASE COUNT 960 a 657 c 717 g 788 t
ORIGIN
1 cgctgcggcc gctatcccct ccggaccatg gccgacgacg acgtgctgtt cgaggatgtg
61 tacgagctgt gcgaggtgat cggaaagggt cccttcagtg ttgtacgacg atgtatcaac
121 agagaaactg ggcaacaatt tgctgtaaaa attgttgatg tagccaagtt cacatcaagt
181 ccagggttaa gtacagaaga tctaaagcgg gaagccagta tctgtcatat gctgaaacat
241 ccacacattg tagagttatt ggagacatat agctcagatg gaatgcttta catggttttc
301 gaatttatgg atggagcaga tctgtgtttt gaaatcgtaa agcgagctga cgctggtttt
361 gtgtacagtg aagctgtagc cagccattat atgagacaga tactggaagc tctacgctac
421 tgccatgata ataacataat tcacagggat gtgaagcccc actgtgttct ccttgcctca
481 aaagaaaact cggcacctgt taaacttgga ggctttgggg tagctattca attaggggag
541 tctggacttg tagctggagg acgtgttgga acacctcatt ttatggcacc agaagtggtc
601 aaaagagagc cttacggaaa gcctgtagac gtctgggggt gcggtgtgat cctttttatc
661 ctgctcagtg gttgtttgcc tttttacgga accaaggaaa gattgtttga aggcattatt
721 aaaggaaaat ataagatgaa tccaaggcag tggagccata tctctgaaag tgccaaagac
781 ctagtacgtc gcatgctgat gctggatcca gctgaaagga tcactgttta tgaagcactg
841 aatcacccat ggcttaagga gcgggatcgt tacgcctaca agattcatct tccagaaaca
901 gtagagcagc tgaggaaatt caatgcaagg aggaaactaa agggtgcagt actagccgct
961 gtgtcaagtc acaaattcaa ctcattctat ggggatcccc ctgaagagtt accagatttc
1021 tccgaagacc ctacctcctc agggcttcta gcagcagaaa gagcagtctc acaggtgctg
1081 gacagcctgg aagagattca tgcgcttaca gactgcagtg aaaaggacct agattttcta
1141 cacagtgttt tccaggatca gcatcttcac acactactag atctgtatga caaaattaac
1201 acaaagtctt caccacaaat caggaatcct ccaagcgatg cagtacagag agccaaagag
1261 gtattggaag aaatttcatg ttaccctgag aataacgacg caaaggaact aaagcgtatt
1321 ttaacacaac ctcatttcat ggccttactt cagactcacg acgtagtggc acatgaagtt
1381 tacagtgatg aagcattgag ggtcacacct cctcccacct ctccctattt aaacggcgat
1441 tctccagaaa gtgctaacgg aggcatggat atggagaatg tgaccagagt tcggctggta
1501 cagtttcaaa agaacacaga tgaaccaatg ggaatcactt taaaaatgaa tgaactaaat
1561 cattgtattg ttgcaagaat tatgcatggg ggcatgattc acaggcaagg tacacttcat
1621 gttggtgatg aaattcgaga aatcaatggc atcagtgtgg ctaaccaaac agtggaacaa
1681 ctgcaaaaaa tgcttaggga aatgcggggg agtattacct tcaagattgt gccaagttac
1741 cgcactcagt cttcgtcctg tgagagagat tccccttcca cttccagaca gtccccagct
1801 aatggtcata gcagcactaa caattctgtt tcggacttgc catcaactac ccaaccaaaa
1861 ggacgacaga tctatgtaag agcacaattt gaatatgatc cagccaagga tgacctcatc
1921 ccctgtaaag aagctggcat tcgattcaga gttggtgaca tcatccagat tattagtaag
1981 gatgatcata attggtggca gggtaaactg gaaaactcca aaaatggaac tgcaggtctc
2041 attccttctt ctgaacttca ggaatggcga gtagcttgca ttgccatgga gaagaccaaa
2101 caggagcagc aggccagctg tacttggttt ggcaagaaaa agaagcagta caaagataaa
2161 tatttggcaa agcacaatgc agatcttgtc acatatgaag aagtagtaaa actgccagca
2221 ttcaagagga aaacactagt cttattaggc gcacatggtg ttgggagaag acacataaaa
2281 aacactctca tcacaaagca cccagaccgg tttgcgtacc ctattccaca tacaaccaga
2341 cctccaaaga gagacgaaga aaatggaaag aattattact ttgtatctca tgaccaaatg
2401 atgcaagaca tctctaataa cgagtacttg gagtacggca gccacgagga tgcgatgtat
2461 gggacaaaac tggagaccat ccggaagatc cacgagcagg ggctgattgc aatactggac
2521 gtggagcctc aggcactgaa ggtcctgaga actgcagagt ttgctccttt tgttgttttc
2581 attgctgcac caactattac tccaggttta aatgaggatg aatctcttca gcgtctgcag
2641 aaggagtctg acatcttaca gagaacatat gcacactact tcgatctcac aattatcaac
2701 aatgaaattg atgagacaat cagacatctg gaggaagctg ttgagctcgt gtgcacagcc
2761 ccacagtggg tccctgtctc ctgggtctat taggcctctc cccagatatc tgagcataac
2821 tgggagcacc tcatttgtgg aaaagcctct ttgttatcgg ccttgtgtca gcaggtcatg
2881 gtccctagag actacctagt tgtagtgtga cctacattta taattattgt catgtccgaa
2941 tagataggag gagaaaaaca attacacact aatttaaaga gacagtatct tttttaatca
3001 gttctcctaa actttaataa aatgtatctt taaatgtatg tattattcaa tcctttggaa
3061 tgttatattt ttggaaatca tagcttttta tttccaaggc ccctaaaact gcacaaaata
3121 ga
//