LOCUS AF030435 3227 bp mRNA linear HUM 25-JUN-1998
DEFINITION Homo sapiens glioma amplified on chromosome 1 protein (GAC1) mRNA,
complete cds.
ACCESSION AF030435
VERSION AF030435.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3227)
AUTHORS Almeida,A., Zhu,X.X., Vogt,N., Tyagi,R., Muleris,M.,
Dutrillaux,A.M., Dutrillaux,B., Ross,D., Malfoy,B. and Hanash,S.
TITLE GAC1, a new member of the leucine-rich repeat superfamily on
chromosome band 1q32.1, is amplified and overexpressed in malignant
gliomas
JOURNAL Oncogene 16 (23), 2997-3002 (1998)
PUBMED 9662332
REFERENCE 2 (bases 1 to 3227)
AUTHORS Malfoy,B., Almeida,A., Zhu,X.X., Vogt,N., Tyagi,R., Muleris,M.,
Dutrillaux,A.-M., Dutrillaux,B., Ross,D. and Hanash,S.
TITLE Direct Submission
JOURNAL Submitted (20-OCT-1997) Section Recherche, UMR147 CNRS-Institut
Curie, 26 rue d'Ulm, Paris 75248, France
FEATURES Location/Qualifiers
source 1..3227
/db_xref="H-InvDB:HIT000063034"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q32.1"
/tissue_type="glioma"
gene 1..3227
/gene="GAC1"
CDS 389..2530
/gene="GAC1"
/codon_start=1
/product="glioma amplified on chromosome 1 protein"
/protein_id="AAC39792.1"
/translation="MRLLVAPLLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPR
SSYREATTVDCNDLFLTAVPPALPAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQ
NSFSDARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRA
FSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAILDMNFRPLANLRSL
VLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRV
GPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHL
PQMETLMLNNNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEP
QSTLCAEPPDLQRLPVREVPFREMTDHCLPLISPRSFPPSLQVASGESMVLHCRALAE
PEPEIYWVTPAGLRLTPAHAGRRCRVYPEGTLELRRVTAEEAGLYTCVAQNLVGADTK
TVSVVVGRALLQPGRDEGQGLELRVQETHPYHILLSWVTPPNTVSTNLTWSSASSLRG
QGATALARLPRGTHSYNITRLLQATEYWACLQVAFADAHTQLACVWARTKEATSCHRA
LGDRPGLIAILALAVLLLAAGLAAHLGTGQPRKGVGGRRPLPPAWAFWGWSAPSVRVV
SAPLVLPWNPGRKLPRSSEGETLLPPLSQNS"
BASE COUNT 654 a 1042 c 892 g 639 t
ORIGIN
1 cagcagacgg cagacggtgc ccggcgccca cgggaagctg aagatacagc ggtatacaaa
61 cctccatgtc tcaagctgac cacacttgta tctggacttg ccagctgatt agctctgttc
121 ccaccaggct cgttcaaaga cccacagctt gagggggcag agggctgccc ctgatggggc
181 ctggcaatga ctgagcaggc ccagccccag aggacaagga agagaaggca tattgaggag
241 ggcaagaagt gacgcccggt gtagaatgac tgccctggga gggtggttcc ttgggccctg
301 gcagggttgc tgacccttac cctgcaaaac acaaagagca ggactccaga ctcttcttgt
361 gaatggtccc ctgccctgca gctccaccat gaggcttctc gtggccccac tcttgctagc
421 ttgggtggct ggtgccactg ccgctgtgcc cgtggtaccc tggcatgttc cctgcccccc
481 tcagtgtgcc tgccagatcc ggccctggta tacgccccgc tcgtcctacc gcgaggctac
541 cactgtggac tgcaatgacc tattcctgac ggcagtcccc ccggcactcc ccgcaggcac
601 acagaccctg ctcctgcaga gcaacagcat tgtccgtgtg gaccagagtg agctgggcta
661 cctggccaat ctcacagagc tggacctgtc ccagaacagc ttttcggatg cccgagactg
721 tgatttccat gcccttcccc agctgctgag cctgcaccta gaggagaacc agctgacccg
781 gctggaggac cacagctttg cagggctggc cagcctacag gaactctatc tcaaccacaa
841 ccagctctac cgcatcgccc ccagggcctt ttctggcctc agcaacttgc tgcggctgca
901 cctcaactcc aacctcctga gggccattga cagccgctgg tttgaaatgc tgcccaactt
961 ggagatactc atgattggcg gcaacaaggt agatgccatc ctggacatga acttccggcc
1021 cctggccaac ctgcgtagcc tggtgctagc aggcatgaac ctgcgggaga tctccgacta
1081 tgccctggag gggctgcaaa gcctggagag cctctccttc tatgacaacc agctggcccg
1141 ggtgcccagg cgggcactgg aacaggtgcc cgggctcaag ttcctagacc tcaacaagaa
1201 cccgctccag cgggtagggc cgggggactt tgccaacatg ctgcacctta aggagctggg
1261 actgaacaac atggaggagc tggtctccat cgacaagttt gccctggtga acctccccga
1321 gctgaccaag ctggacatca ccaataaccc acggctgtcc ttcatccacc cccgcgcctt
1381 ccaccacctg ccccagatgg agaccctcat gctcaacaac aacgctctca gtgccttgca
1441 ccagcagacg gtggagtccc tgcccaacct gcaggaggta ggtctccacg gcaaccccat
1501 ccgctgtgac tgtgtcatcc gctgggccaa tgccacgggc acccgtgtcc gcttcatcga
1561 gccgcaatcc accctgtgtg cggagcctcc ggacctccag cgcctcccgg tccgtgaggt
1621 gcccttccgg gagatgacgg accactgttt gcccctcatc tccccacgaa gcttcccccc
1681 aagcctccag gtagccagtg gagagagcat ggtgctgcat tgccgggcac tggccgaacc
1741 cgaacccgag atctactggg tcactccagc tgggcttcga ctgacacctg cccatgcagg
1801 caggaggtgc cgggtgtacc ccgaggggac cctggagctg cggagggtga cagcagaaga
1861 ggcagggcta tacacctgtg tggcccagaa cctggtgggg gctgacacta agacggttag
1921 tgtggttgtg ggccgtgctc tcctccagcc aggcagggac gaaggacagg ggctggagct
1981 ccgggtgcag gagacccacc cctatcacat cctgctatct tgggtcaccc cacccaacac
2041 agtgtccacc aacctcacct ggtccagtgc ctcctccctc cggggccagg gggccacagc
2101 tctggcccgc ctgcctcggg gaacccacag ctacaacatt acccgcctcc ttcaggccac
2161 ggagtactgg gcctgcctgc aagtggcctt tgctgatgcc cacacccagt tggcttgtgt
2221 atgggccagg accaaagagg ccacttcttg ccacagagcc ttaggggatc gtcctgggct
2281 cattgccatc ctggctctcg ctgtccttct cctggcagct gggctagcgg cccaccttgg
2341 cacaggccaa cccaggaagg gtgtgggtgg gaggcggcct ctccctccag cctgggcttt
2401 ctggggctgg agtgcccctt ctgtccgggt tgtgtctgct cccctcgtcc tgccctggaa
2461 tccagggagg aagctgccca gatcctcaga aggggagaca ctgttgccac cattgtctca
2521 aaattcttga agctcagcct gttctcagca gtagagaaat cactaggact actttttacc
2581 aaaagagaag cagtctgggc cagatgccct gccaggaaag ggacatggac ccacgtgctt
2641 gaggcctggc agctgggcca agacagatgg ggctttgtgg ccctgggggt gcttctgcag
2701 ccttgaaaaa gttgccctta cctcctaggg tcacctctgc tgccattctg aggaacatct
2761 ccaaggaacg ggagggactt tggctagagc ctcctgcctc cccatcttct ctctgcccag
2821 aggctcctgg gcctggcttg gctgtcccct acctgtgtcc ccgggctgca ccccttcctc
2881 ttctctttct ctgtacagtc tcagttgctt gctcttgtgc ctcctgggca agggctgaag
2941 gaggccactc catctcacct cggggggctg ccctcaatgt gggagtgacc ccagccagat
3001 ctgaaggaca tttgggagag ggatgcccag gaacgcctca tctcagcagc ctgggctcgg
3061 cattccgaag ctgactttct ataggcaatt ttgtaccttt gtggagaaat gtgtcacctc
3121 ccccaacccg attcactctt ttctcctgtt ttgtaaaaaa taaaaataaa taataacaat
3181 aatacggggg aaaggaacga aaggaactaa aaaaaaaaaa aaaaaaa
//