LOCUS AF030339 5121 bp mRNA linear HUM 03-JUN-1998
DEFINITION Homo sapiens receptor for viral semaphorin protein (VESPR) mRNA,
complete cds.
ACCESSION AF030339
VERSION AF030339.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5121)
AUTHORS Comeau,M.R., Johnson,R., DuBose,R.F., Petersen,M., Gearing,P.,
VandenBos,T., Park,L., Farrah,T., Buller,R.M., Cohen,J.I.,
Strockbine,L.D., Rauch,C. and Spriggs,M.K.
TITLE A poxvirus-encoded semaphorin induces cytokine production from
monocytes and binds to a novel cellular semaphorin receptor, VESPR
JOURNAL Immunity 8 (4), 473-482 (1998)
PUBMED 9586637
REFERENCE 2 (bases 1 to 5121)
AUTHORS Comeau,M.C. and Spriggs,M.K.
TITLE Direct Submission
JOURNAL Submitted (17-OCT-1997) Molecular Biology, Immunex, 51 University
St., Seattle, WA 98101-2936, USA
FEATURES Location/Qualifiers
source 1..5121
/db_xref="H-InvDB:HIT000063027"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="fibroblast"
/tissue_type="foreskin"
gene 1..5121
/gene="VESPR"
/note="viral encoded semaphorin protein receptor"
CDS 250..4956
/gene="VESPR"
/note="receptor for viral semaphorin protein"
/codon_start=1
/product="VESPR"
/protein_id="AAC18823.1"
/translation="MEVSRRKAPPRPPRPAAPLPLLAYLLALAAPGRGADEPVWRSEQ
AIGAIAASQEDGVFVASGSCLDQLDYSLEHSLSRLYRDQAGNCTEPVSLAPPARPRPG
SSFSKLLLPYREGAAGLGGLLLTGWTFDRGACEVRPLGNLSRNSLRNGTEVVSCHPQG
STAGVVYRAGRNNRWYLAVAATYVLPEPETASRCNPAASDHDTAIALKDTEGRSLATQ
ELGRLKLCEGAGSLHFVDAFLWNGSIYFPYYPYNYTSGAATGWPSMARIAQSTEVLFQ
GQASLDCGHGHPDGRRLLLSSSLVEALDVWAGVFSAAAGEGQERRSPTTTALCLFRMS
EIQARAKRVSWDFKTAESHCKEGDQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFL
GTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVRRI
RVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPK
IQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVDSSRELCQNKSQPNRTCTCSIPTRATY
KDVSVVNVMFSFGSWNLSDRFNFTNCSSLKECPACVETGCAWCKSARRCIHPFTACDP
SDYERNQEQCPVAVEKTSGGGRPKENKGNRTNQALQVFYIKSIEPQKVSTLGKSNVIV
TGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSLPSSRKEMKDVCIQFDGG
NCSSVGSLSYIALPHCSLIFPATTWISGGQNITMMGRNFDVIDNLIISHELKGNINVS
EYCVATYCGFLAPSLKSSKVRTNVTVKLRVQDTYLDCGTLQYREDPRFTGYRVESEVD
TELEVKIQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQDLTTILCKIKGIKT
ASTIANSSKKVRVKLGNLELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKE
LSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKHFALRTFFPES
GGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRCLFA
SFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCLS
GFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVV
FEKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQM
GTRQKELLDIDSSSVILEDGITKLNTIGHYEISNGSTIKVFKKIANFTSDVEYSDDHC
HLILPDSEAFQDVQGKRHRGKHKFKVKEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNS
RAPFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTP
HIDGCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPP
LSSSEMEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQL
LHVKVLFDEKKKCKWM"
BASE COUNT 1362 a 1304 c 1313 g 1142 t
ORIGIN
1 gcgaggagga aacggtgccg gagcgcgcag ggcttgctgc cgccaccgcc gctgcacagg
61 ctgccggagc gagcctgccg cgcgccgccc tccccgctct ccttcctggg cgagctgcgg
121 ggatggggcg gccgcgggag cccgagcgcg cgcaggaacc gccgccgccg ccgcccgcgt
181 ctccgttgcc gcgcgcctga gccgccgtcg ccgccgcgcg ccctgcccgg gggcggcccc
241 cccagcccca tggaggtctc ccggaggaag gcgccgccgc gccccccgcg ccccgcagcg
301 ccactgcccc tgctcgccta tctgctggca ctggcggctc ccggccgggg cgcggacgag
361 cccgtgtggc ggtcggagca agccatcgga gccatcgcgg cgagccagga ggacggcgtg
421 tttgtggcga gcggcagctg cctggaccag ctggactaca gcctggagca cagcctctcg
481 cgcctgtacc gggaccaagc gggcaactgc acagagccgg tctcgctggc gccccccgcg
541 cggccccggc ccgggagcag cttcagcaag ctgctgctgc cctaccgcga gggggcggcc
601 ggcctcgggg ggctgctgct caccggctgg accttcgacc ggggcgcctg cgaggtgcgg
661 cccctgggca acctgagccg caactccctg cgcaacggca ccgaggtggt gtcgtgccac
721 ccgcagggct cgacggccgg cgtggtgtac cgcgcgggcc ggaacaaccg ctggtacctg
781 gcggtggccg ccacctacgt gctgcctgag ccggagacgg cgagccgctg caaccccgcg
841 gcatccgacc acgacacggc catcgcgctc aaggacacgg aggggcgcag cctggccacg
901 caggagctgg ggcgcctcaa gctgtgcgag ggcgcgggca gcctgcactt cgtggacgcc
961 tttctctgga acggcagcat ctacttcccc tactacccct acaactatac gagcggcgct
1021 gccaccggct ggcccagcat ggcgcgcatc gcgcagagca ccgaggtgct gttccagggc
1081 caggcatccc tcgactgcgg ccacggccac cccgacggcc gccgcctgct cctctcctcc
1141 agcctagtgg aggccctgga cgtctgggcg ggagtgttca gcgcggccgc tggagagggc
1201 caggagcggc gctcccccac caccacggcg ctctgcctct tcagaatgag tgagatccag
1261 gcgcgcgcca agagggtcag ctgggacttc aagacggccg agagccactg caaagaaggg
1321 gatcaacctg aaagagtcca accaatcgca tcatctacct tgatccattc cgacctgaca
1381 tccgtttatg gcaccgtggt aatgaacagg actgttttat tcttggggac tggagatggc
1441 cagttactta aggttattct tggtgagaat ttgacttcaa attgtccaga ggttatctat
1501 gaaattaaag aagagacacc tgttttctac aaactcgttc ctgatcctgt gaagaatatc
1561 tacatttatc taacagctgg gaaagaggtg aggagaattc gtgttgcaaa ctgcaataaa
1621 cataaatcct gttcggagtg tttaacagcc acagaccctc actgcggttg gtgccattcg
1681 ctacaaaggt gcacttttca aggagattgt gtacattcag agaacttaga aaactggctg
1741 gatatttcgt ctggagcaaa aaagtgccct aaaattcaga taattcgaag cagtaaagaa
1801 aagactacag tgactatggt gggaagcttc tctccaagac actcaaagtg catggtgaag
1861 aatgtggact ctagcaggga gctctgccag aataaaagtc agcccaaccg gacctgcacc
1921 tgtagcatcc caaccagagc aacctacaaa gatgtttcag ttgtcaacgt gatgttctcc
1981 ttcggttctt ggaatttatc agacagattc aactttacca actgctcatc attaaaagaa
2041 tgcccagcat gcgtagaaac tggctgcgcg tggtgtaaaa gtgcaagaag gtgtatccac
2101 cccttcacag cttgcgaccc ttctgattat gagagaaacc aggaacagtg tccagtggct
2161 gtcgagaaga catcaggagg aggaagaccc aaggagaaca aggggaacag aaccaaccag
2221 gctttacagg tcttctacat taagtccatt gagccacaga aagtatcgac attagggaaa
2281 agcaacgtga tagtaacggg agcaaacttt acccgggcat cgaacatcac aatgatcctg
2341 aaaggaacca gtacctgtga taaggatgtg atacaggtta gccatgtgct aaatgacacc
2401 cacatgaaat tctctcttcc atcaagccgg aaagaaatga aggatgtgtg tatccagttt
2461 gatggtggga actgctcttc tgtgggatcc ttatcctaca ttgctctgcc acattgttcc
2521 cttatatttc ctgctaccac ctggatcagt ggtggtcaaa atataaccat gatgggcaga
2581 aattttgatg taattgacaa cttaatcatt tcacatgaat taaaaggaaa cataaatgtc
2641 tctgaatatt gtgtggcgac ttactgcggg tttttagccc ccagtttaaa gagttcaaaa
2701 gtgcgcacga atgtcactgt gaagctgaga gtacaagaca cctacttgga ttgtggaacc
2761 ctgcagtatc gggaggaccc cagattcacg gggtatcggg tggaatccga ggtggacaca
2821 gaactggaag tgaaaattca aaaagaaaat gacaacttca atatttccaa aaaagacatt
2881 gaaattactc tcttccatgg ggaaaatggg caattaaatt gcagttttga aaatattact
2941 agaaatcaag atcttaccac catcctttgc aaaattaaag gcatcaagac tgcaagcacc
3001 attgccaact cttctaagaa agttcgggtc aagctgggaa acctggagct ctacgtcgag
3061 caggagtcag ttccttccac atggtatttt ctgattgtgc tccctgtctt gctagtgatt
3121 gtcatttttg cggccgtggg ggtgaccagg cacaaatcga aggagctgag tcgcaaacag
3181 agtcaacaac tagaattgct ggaaagcgag ctccggaaag agatacgtga cggctttgct
3241 gagctgcaga tggataaatt ggatgtggtt gatagttttg gaactgttcc cttccttgac
3301 tacaaacatt ttgctctgag aactttcttc cctgagtcag gtggcttcac ccacatcttc
3361 actgaagata tgcataacag agacgccaac gacaagaatg aaagtctcac agctttggat
3421 gccctaatct gtaataaaag ctttcttgtt actgtcatcc acacccttga aaagcagaag
3481 aacttttctg tgaaggacag gtgtctgttt gcctccttcc taaccattgc actgcaaacc
3541 aagctggtct acctgaccag catcctagag gtgctgacca gggacttgat ggaacagtgt
3601 agtaacatgc agccgaaact catgctgaga cgcacggagt ccgtcgtcga aaaactcctc
3661 acaaactgga tgtccgtctg cctttctgga tttctccggg agactgtcgg agagcccttc
3721 tatttgctgg tgacgactct gaaccagaaa attaacaagg gtcccgtgga tgtaatcact
3781 tgcaaagccc tgtacacact taatgaagac tggctgttgt ggcaggttcc ggaattcagt
3841 actgtggcat taaacgtcgt ctttgaaaaa atcccggaaa acgagagtgc agatgtctgt
3901 cggaatattt cagtcaatgt tctcgactgt gacaccattg gccaagccaa agaaaagatt
3961 ttccaagcat tcttaagcaa aaatggctct ccttatggac ttcagcttaa tgaaattggt
4021 cttgagcttc aaatgggcac acgacagaaa gaacttctgg acatcgacag ttcctccgtg
4081 attcttgaag atggaatcac caagctaaac accattggcc actatgagat atcaaatgga
4141 tccactataa aagtctttaa gaagatagca aattttactt cagatgtgga gtactcggat
4201 gaccactgcc atttgatttt accagattcg gaagcattcc aagatgtgca aggaaagaga
4261 catcgaggga agcacaagtt caaagtaaaa gaaatgtatc tgacaaagct gctgtcgacc
4321 aaggtggcaa ttcattctgt gcttgaaaaa ctttttagaa gcatttggag tttacccaac
4381 agcagagctc catttgctat aaaatacttt tttgactttt tggacgccca ggctgaaaac
4441 aaaaaaatca cagatcctga cgtcgtacat atttggaaaa caaacagcct tcctcttcgc
4501 ttctgggtaa acatcctgaa gaaccctcag tttgtctttg acattaagaa gacaccacat
4561 atagacggct gtttgtcagt gattgcccag gcattcatgg atgcattttc tctcacagag
4621 cagcaactag ggaaggaagc accaactaat aagcttctct atgccaagga tatcccaacc
4681 tacaaagaag aagtaaaatc ttattacaaa gcaatcaggg atttgcctcc attgtcatcc
4741 tcagaaatgg aagaattttt aactcaggaa tctaagaaac atgaaaatga atttaatgaa
4801 gaagtggcct tgacagaaat ttacaaatac atcgtaaaat attttgatga gattctaaat
4861 aaactagaaa gagaacgagg gctggaagaa gctcagaaac aactcttgca tgtaaaagtc
4921 ttatttgatg aaaagaagaa atgcaagtgg atgtaagcac tctggggcct ggcttaatct
4981 ggcaaagttc ttcagacgac ttgggagcaa aatggctgct tgagctactc tgtgtcgtta
5041 atttgttgtt tgcacatagg ttccactttg ggcactgtct ttttaagaga ccaaggcaca
5101 tgcacagctt ttagaaagca a
//