LOCUS AF030186 3724 bp mRNA linear HUM 04-NOV-1998
DEFINITION Homo sapiens glypican-4 (GPC4) mRNA, complete cds.
ACCESSION AF030186
VERSION AF030186.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3724)
AUTHORS Veugelers,M., Vermeesch,J., Watanabe,K., Yamaguchi,Y., Marynen,P.
and David,G.
TITLE GPC4, the gene for human K-glypican, flanks GPC3 on xq26: deletion
of the GPC3-GPC4 gene cluster in one family with
Simpson-Golabi-Behmel syndrome
JOURNAL Genomics 53 (1), 1-11 (1998)
PUBMED 9787072
REFERENCE 2 (bases 1 to 3724)
AUTHORS Veugelers,M., Vermeesch,J., Marynen,P. and David,G.
TITLE Direct Submission
JOURNAL Submitted (15-OCT-1997) Department of Molecular Cell Biology,
Faculty of Medicine, Center for Human Genetics, K.U. Leuven, Campus
Gasthuisberg, O&N6, Herestraat 49, Leuven 3000, Belgium
FEATURES Location/Qualifiers
source 1..3724
/db_xref="H-InvDB:HIT000063019"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xq26"
/tissue_type="brain"
/dev_stage="fetal"
gene 1..3724
/gene="GPC4"
CDS 213..1883
/gene="GPC4"
/function="putative cell surface receptor for growth and
adhesion factors"
/note="heparan sulfate proteoglycan; glycosyl
phosphatidylinositol-anchored (glypiated) cell surface
proteoglycan"
/codon_start=1
/product="glypican-4"
/protein_id="AAC69991.1"
/translation="MARFGLPALLCTLAVLSAALLAAELKSKSCSEVRRLYVSKGFNK
NDAPLHEINGDHLKICPQGSTCCSQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRY
KKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVVGNVNLEEM
LNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAA
RTFAQGLAVAGDVVSKVSVVNPTAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRG
CLANQGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVS
QKVFQGCGPPKPLPAGRISRSISESAFSARFRPHHPEERPTTAAGTSLDRLVTDVKDK
LKQAKKFWSSLPSNVCNDERMAAGNGNEDDCWNGKGKSRYLFAVTGNGLVNQGNNPEV
QVDTSKPDILILRQIMALRVMTSKMKNAYNGNDVDFFDISDESSGEGSGSGCEYQQCP
SEFDYNATDHAGKSANEKADSAGVRPGAQAYLLTVFCILFLVMQREWR"
BASE COUNT 987 a 825 c 858 g 1052 t
ORIGIN
1 gcctggcacc ggggaccgtt gcctgacgcg aggcccagct ctacttttcg ccccgcgtct
61 cctccgcctg ctcgcctctt ccaccaactc caactccttc tccctccagc tccactcgct
121 agtccccgac tccgccagcc ctcggcccgc tgccgtagcg ccgcttcccg tccggtccca
181 aaggtgggaa cgtgtccgcc ccggcccgca ccatggcacg gttcggcttg cccgcgcttc
241 tctgcaccct ggcagtgctc agcgccgcgc tgctggctgc cgagctcaag tcgaaaagtt
301 gctcggaagt gcgacgtctt tacgtgtcca aaggcttcaa caagaacgat gcccccctcc
361 acgagatcaa cggtgatcat ttgaagatct gtccccaggg ttctacctgc tgctctcaag
421 agatggagga gaagtacagc ctgcaaagta aagatgattt caaaagtgtg gtcagcgaac
481 agtgcaatca tttgcaagct gtctttgctt cacgttacaa gaagtttgat gaattcttca
541 aagaactact tgaaaatgca gagaaatccc tgaatgatat gtttgtgaag acatatggcc
601 atttatacat gcaaaattct gagctattta aagatctctt cgtagagttg aaacgttact
661 acgtggtggg aaatgtgaac ctggaagaaa tgctaaatga cttctgggct cgcctcctgg
721 agcggatgtt ccgcctggtg aactcccagt accactttac agatgagtat ctggaatgtg
781 tgagcaagta tacggagcag ctgaagccct tcggagatgt ccctcgcaaa ttgaagctcc
841 aggttactcg tgcttttgta gcagcccgta ctttcgctca aggcttagcg gttgcgggag
901 atgtcgtgag caaggtctcc gtggtaaacc ccacagccca gtgtacccat gccctgttga
961 agatgatcta ctgctcccac tgccggggtc tcgtgactgt gaagccatgt tacaactact
1021 gctcaaacat catgagaggc tgtttggcca accaagggga tctcgatttt gaatggaaca
1081 atttcataga tgctatgctg atggtggcag agaggctaga gggtcctttc aacattgaat
1141 cggtcatgga tcccatcgat gtgaagattt ctgatgctat tatgaacatg caggataata
1201 gtgttcaagt gtctcagaag gttttccagg gatgtggacc ccccaagccc ctcccagctg
1261 gacgaatttc tcgttccatc tctgaaagtg ccttcagtgc tcgcttcaga ccacatcacc
1321 ccgaggaacg cccaaccaca gcagctggca ctagtttgga ccgactggtt actgatgtca
1381 aggataaact gaaacaggcc aagaaattct ggtcctccct tccgagcaac gtttgcaacg
1441 atgagaggat ggctgcagga aacggcaatg aggatgactg ttggaatggg aaaggcaaaa
1501 gcaggtacct gtttgcagtg acaggaaatg gattagtcaa ccagggcaac aacccagagg
1561 tccaggttga caccagcaaa ccagacatac tgatccttcg tcaaatcatg gctcttcgag
1621 tgatgaccag caagatgaag aatgcataca atgggaacga cgtggacttc tttgatatca
1681 gtgatgaaag tagtggagaa ggaagtggaa gtggctgtga gtatcagcag tgcccttcag
1741 agtttgacta caatgccact gaccatgctg ggaagagtgc caatgagaaa gccgacagtg
1801 ctggtgtccg tcctggggca caggcctacc tcctcactgt cttctgcatc ttgttcctgg
1861 ttatgcagag agagtggaga taattctcaa actctgagaa aaagtgttca tcaaaaagtt
1921 aaaaggcacc agttatcact tttctaccat cctagtgact ttgcttttta aatgaatgga
1981 caacaatgta cagtttttac tatgtggcca ctggtttaag aagtgctgac tttgttttct
2041 cattcagttt tgggaggaaa agggactgtg cattgagttg gttcctgctc ccccaaacca
2101 tgttaaacgt ggctaacagt gtaggtacag aactatagtt agttgtgcat ttgtgatttt
2161 atcactctat tatttgtttg tatgtttttt tctcatttcg tttgtgggtt tttttttcca
2221 actgtgatct cgccttgttt cttacaagca aaccagggtc ccttcttggc acgtaacatg
2281 tacgtatttc tgaaatatta aatagctgta cagaagcagg ttttatttat catgttatct
2341 tattaaaaga aaaagcccaa aaagcagtaa aatttccatt tctccctgtt attttagttg
2401 ccttatctgg agagacgtgg aggtgatttt ctttttttaa attattatta agacagaatg
2461 tgaaggcaca agcaggcttc tgagccactt gtcagattgt attcaaagca tcaatccaag
2521 aggaggttat gtgtacttca tttattggtg atagttggaa gagactgcag actactgctt
2581 tgaatgagtt gaattacata agctaagatc actataaggt ccatttcttg aacccactta
2641 tacataaaat gtaacccatt tagaaaaaga ttctggatat catcccccct tgaaagatag
2701 aaagcattca ggatgtccca gttatcacat gttcacactt gggtttaggg gtgttttttt
2761 ttaaaaccag gcaggttagc tagcccaccc tgtgctagtt ttcatgttca cgctgaccct
2821 atttgaatta atatcctttg ttagagtggt cgagatttca aacccaatta tgtacangga
2881 gctgtctgag agctagccag aactggggta cagcctgggc tcagggaata gctgtcaaca
2941 ctcgggcaaa gtttttgtct gcagcaacgt gtatcaccat ttgttttggg atccagtttt
3001 tgttttaaga gagtataagg tgtctcattt gagtcttttt cttacctagc cccctcttat
3061 cagtaaaaca aaggacttgc catggttcac agcaatgtgc tacgatccaa gatatcaacc
3121 aaggagccca cttaggggag aactaggtgt ccagattttt gtatgtgttg tttttcttgg
3181 gggatggggt ggggtgggag taggtagagc tgagaatact acatcttagt ggtgaccttt
3241 agccacgtgg gtgaagtggc aaaggccatg gccatatctg ttgtcccagg ccaaagacta
3301 acaactgcct tgggaatccc ttccttgtgt ccttaccaaa tgatagctca taaaactctg
3361 ataatgtaac aaatcacttn caaaggagtt cccagaagtc ttcagaaaga ctaaaattct
3421 gtctcttcct gctttagaca gccattaaga tcccaactaa ttttaccgaa cctaaaaccc
3481 acaaagaggt tgtttgtgtt attgttcaat cttcagttgt aagagtaatt ctctattttt
3541 atattgaaac ataattactt gatagctcag ggtctacact tcattcaact ttttacacca
3601 aattctgcag agtggtcaaa atggaatatt gggggctgtt gtaaacagag gcttaatttt
3661 attagaagta gccagttatt tattaaagca tgatgttaat aaaataggca tattccaaaa
3721 aaaa
//