LOCUS AF029778 4974 bp mRNA linear HUM 28-FEB-2000
DEFINITION Homo sapiens Jagged2 (JAG2) mRNA, complete cds.
ACCESSION AF029778
VERSION AF029778.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4974)
AUTHORS Deng,Y., Madan,A., Banta,A.B., Friedman,C., Trask,B.J., Hood,L. and
Li,L.
TITLE Characterization, chromosomal localization, and the complete 30-kb
DNA sequence of the human Jagged2 (JAG2) gene
JOURNAL Genomics 63 (1), 133-138 (2000)
PUBMED 10662552
REFERENCE 2 (bases 1 to 4974)
AUTHORS Li,L., Deng,Y., Banta,B.A. and Hood,L.
TITLE Human homolog of rat Jagged2, which encodes a ligand for Notch
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 4974)
AUTHORS Li,L., Deng,Y., Banta,B.A. and Hood,L.
TITLE Direct Submission
JOURNAL Submitted (13-OCT-1997) Molecular Biotechnology, University of
Washington, Seattle, WA 98195, USA
FEATURES Location/Qualifiers
source 1..4974
/db_xref="H-InvDB:HIT000062993"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q32"
/tissue_type="bone marrow"
gene 1..4974
/gene="JAG2"
CDS 405..4121
/gene="JAG2"
/note="Notch ligand"
/codon_start=1
/product="Jagged2"
/protein_id="AAB84215.1"
/translation="MRAQGRGRLPRRLLLLLALWVQAARPMGYFELQLSALRNVNGEL
LSGACCDGDGRTTRAGGCGHDECDTYVRVCLKEYQAKVTPTGPCSYGHGATPVLGGNS
FYLPPAGAAGDRARARARAGGDQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPNEE
LLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCNKFCRPRNDFF
GHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDEC
VPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCT
CPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASN
PCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCI
PGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDKCASSPCH
SGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF
GGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCIC
DSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDP
CHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPP
GWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPC
YNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPG
RAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLA
GQPEALSAQCPLGQRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNCAR
LTLHFNRDHVPQGTTVGAICSGIRSLPATRAVARDRLLVLLCDRASSGASAVEVAVSF
SPARDLPDSSLIQGAAHAIVAAITQRGNSSLLLAVTEVKVETVVTGGSSTGLLVPVLC
GAFSVLWLACVVLCVWWTRKRRKERERSRLPREESANNQWAPLNPIRNPIERPGGHKD
VLYQCKNFTPPPRRADEALPGPAGHAAVREDEEDEDLGRGEEDSLEAEKFLSHKFTKD
PGRSPGRPAHWASGPKVDNRAVRSINEARYAGKE"
BASE COUNT 807 a 1589 c 1698 g 880 t
ORIGIN
1 ctcatgcata tgcaggtgcg cgggtgacga atgggcgagc gagctgtcag tctcgttccg
61 aacttgttgg ctgcggtgcc gggagcgcgg gcgcgcagag cccgaggccg ggacccgctg
121 ccttcaccgc cgccgccgtc gccgccgggt gggagccggg ccgggcagcc ggagcgcggc
181 cgccagcgag ccggagctgc cgccgcccct gcacgcccgc cgcccaggcc cgcgcgccgg
241 acgctgcgct cgaccccgcc cgcgccgccg ccgccgccgc ctctgccgct gccgctgcct
301 ctgcgggcgc tcggagggcg ggcgggcgct gggaggccgg cgcggcggct gggagccggg
361 cgcgggcggc ggcggcgggg ccgggcgggc gggtcgcggg ggcaatgcgg gcgcagggcc
421 gggggcgcct tccccggcgg ctgctgctgc tgctggcgct ctgggtgcag gcggcgcggc
481 ccatgggcta tttcgagctg cagctgagcg cgctgcggaa cgtgaacggg gagctgctga
541 gcggcgcctg ctgtgacggc gacggccgga caacgcgcgc ggggggctgc ggccacgacg
601 agtgcgacac gtacgtgcgc gtgtgcctta aggagtacca ggccaaggtg acgcccacgg
661 ggccctgcag ctacggccac ggcgccacgc ccgtgctggg cggcaactcc ttctacctgc
721 cgccggcggg cgctgcgggg gaccgagcgc gggcgcgggc ccgggccggc ggcgaccagg
781 acccgggcct cgtcgtcatc cccttccagt tcgcctggcc gcgctccttt accctcatcg
841 tggaggcctg ggactgggac aacgatacca ccccgaatga ggagctgctg atcgagcgag
901 tgtcgcatgc cggcatgatc aacccggagg accgctggaa gagcctgcac ttcagcggcc
961 acgtggcgca cctggagctg cagatccgcg tgcgctgcga cgagaactac tacagcgcca
1021 cttgcaacaa gttctgccgg ccccgcaacg actttttcgg ccactacacc tgcgaccagt
1081 acggcaacaa ggcctgcatg gacggctgga tgggcaagga gtgcaaggaa gctgtgtgta
1141 aacaagggtg taatttgctc cacgggggat gcaccgtgcc tggggagtgc aggtgcagct
1201 acggctggca agggaggttc tgcgatgagt gtgtccccta ccccggctgc gtgcatggca
1261 gttgtgtgga gccctggcag tgcaactgtg agaccaactg gggcggcctg ctctgtgaca
1321 aagacctgaa ctactgtggc agccaccacc cctgcaccaa cggaggcacg tgcatcaacg
1381 ccgagcctga ccagtaccgc tgcacctgcc ctgacggcta ctcgggcagg aactgtgaga
1441 aggctgagca cgcctgcacc tccaacccgt gtgccaacgg gggctcttgc catgaggtgc
1501 cgtccggctt cgaatgccac tgcccatcgg gctggagcgg gcccacctgt gcccttgaca
1561 tcgatgagtg tgcttcgaac ccgtgtgcgg ccggtggcac ctgtgtggac caggtggacg
1621 gctttgagtg catctgcccc gagcagtggg tgggggccac ctgccagctg gacgccaatg
1681 agtgtgaagg gaagccatgc cttaacgctt tttcttgcaa aaacctgatt ggcggctatt
1741 actgtgattg catcccgggc tggaagggca tcaactgcca tatcaacgtc aacgactgtc
1801 gcgggcagtg tcagcatggg ggcacctgca aggacctggt gaacgggtac cagtgtgtgt
1861 gcccacgggg cttcggaggc cggcattgcg agctggaacg agacaagtgt gccagcagcc
1921 cctgccacag cggcggcctc tgcgaggacc tggccgacgg cttccactgc cactgccccc
1981 agggcttctc cgggcctctc tgtgaggtgg atgtcgacct ttgtgagcca agcccctgcc
2041 ggaacggcgc tcgctgctat aacctggagg gtgactatta ctgcgcctgc cctgatgact
2101 ttggtggcaa gaactgctcc gtgccccgcg agccgtgccc tggcggggcc tgcagagtga
2161 tcgatggctg cgggtcagac gcggggcctg ggatgcctgg cacagcagcc tccggcgtgt
2221 gtggccccca tggacgctgc gtcagccagc cagggggcaa cttttcctgc atctgtgaca
2281 gtggctttac tggcacctac tgccatgaga acattgacga ctgcctgggc cagccctgcc
2341 gcaatggggg cacatgcatc gatgaggtgg acgccttccg ctgcttctgc cccagcggct
2401 gggagggcga gctctgcgac accaatccca acgactgcct tcccgatccc tgccacagcc
2461 gcggccgctg ctacgacctg gtcaatgact tctactgtgc gtgcgacgac ggctggaagg
2521 gcaagacctg ccactcacgc gagttccagt gcgatgccta cacctgcagc aacggtggca
2581 cctgctacga cagcggcgac accttccgct gcgcctgccc ccccggctgg aagggcagca
2641 cctgcgccgt cgccaagaac agcagctgcc tgcccaaccc ctgtgtgaat ggtggcacct
2701 gcgtgggcag cggggcctcc ttctcctgca tctgccggga cggctgggag ggtcgtactt
2761 gcactcacaa taccaacgac tgcaaccctc tgccttgcta caatggtggc atctgtgttg
2821 acggcgtcaa ctggttccgc tgcgagtgtg cacctggctt cgcggggcct gactgccgca
2881 tcaacatcga cgagtgccag tcctcgccct gtgcctacgg ggccacgtgt gtggatgaga
2941 tcaacgggta tcgctgtagc tgcccacccg gccgagccgg cccccggtgc caggaagtga
3001 tcgggttcgg gagatcctgc tggtcccggg gcactccgtt cccacacgga agctcctggg
3061 tggaagactg caacagctgc cgctgcctgg atggccgccg tgactgcagc aaggtgtggt
3121 gcggatggaa gccttgtctg ctggccggcc agcccgaggc cctgagcgcc cagtgcccac
3181 tggggcaaag gtgcctggag aaggccccag gccagtgtct gcgaccaccc tgtgaggcct
3241 ggggggagtg cggcgcagaa gagccaccga gcaccccctg cctgccacgc tccggccacc
3301 tggacaataa ctgtgcccgc ctcaccttgc atttcaaccg tgaccacgtg ccccagggca
3361 ccacggtggg cgccatttgc tccgggatcc gctccctgcc agccacaagg gctgtggcac
3421 gggaccgcct gctggtgttg ctttgcgacc gggcgtcctc gggggccagt gccgtggagg
3481 tggccgtgtc cttcagccct gccagggacc tgcctgacag cagcctgatc cagggcgcgg
3541 cccacgccat cgtggccgcc atcacccagc gggggaacag ctcactgctc ctggctgtca
3601 ccgaggtcaa ggtggagacg gttgttacgg gcggctcttc cacaggtctg ctggtgcctg
3661 tgctgtgtgg tgccttcagc gtgctgtggc tggcgtgcgt ggtcctgtgc gtgtggtgga
3721 cacgcaagcg caggaaagag cgggagagga gccggctgcc gcgggaggag agcgccaaca
3781 accagtgggc cccgctcaac cccatccgca accccatcga gcggccgggg ggccacaagg
3841 acgtgctcta ccagtgcaag aacttcacgc cgccgccgcg cagggcggac gaggcgctgc
3901 ccgggccggc cggccacgcg gccgtcaggg aggatgagga ggacgaggat ctgggccgcg
3961 gtgaggagga ctccctggag gcggagaagt tcctctcaca caaattcacc aaagatcctg
4021 gccgctcgcc ggggaggccg gcccactggg cctcaggccc caaagtggac aaccgcgcgg
4081 tcaggagcat caatgaggcc cgctacgccg gcaaggagta ggggcggctg ccagctgggc
4141 cgggacccag ggccctcggt gggagccatg ccgtctgccg gacccggagg ccgaggccat
4201 gtgcatagtt tctttatttt gtgtaaaaaa accaccaaaa acaaaaacca aatgtttatt
4261 ttctacgttt ctttaacctt gtataaatta ttcagtaact gtcaggctga aaacaatgga
4321 gtattctcgg atagttgcta tttttgtaaa gtttccgtgc gtggcactcg ctgtatgaaa
4381 ggagagagca aagggtgtct gcgtcgtcac caaatcgtag cgtttgttac cagaggttgt
4441 gcactgttta cagaatcttc cttttattcc tcactcgggt ttctctgtgg ctccaggcca
4501 aagtgccggt gagacccatg gctgtgttgg tgtggcccat ggctgttggt gggacccgtg
4561 gctgatggtg tggcctgtgg ctgtcggtgg gactcgtggc tgtcaatggg acctgtggct
4621 gtcggtggga cctacggtgg tcggtgggac cctggttatt gatgtggccc tggctgccgg
4681 cacggcccgt ggctgttgac gcacctgtgg ttgttagtgg ggcctgaggt catcggcgtg
4741 gcccaaggcc ggcaggtcaa cctcgcgctt gctggccagt ccaccctgcc tgccgtctgt
4801 gcttcctcct gcccagaacg cccgctccag cgatctctcc actgtgcttt cagaagtgcc
4861 cttcctgctg cgaagttctc ccatcctggg acggcggcag tattgaagct cgtgacaagt
4921 gccttcacac agaaccctcg gaactgtcca cgcgttccgt gggaacaagg ggtt
//