LOCUS AF029761 1726 bp mRNA linear HUM 08-JAN-1999
DEFINITION Homo sapiens decoy receptor 2 mRNA, complete cds.
ACCESSION AF029761
VERSION AF029761.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1726)
AUTHORS Marsters,S.A., Sheridan,J.P., Pitti,R.M., Huang,A., Skubatch,M.,
Baldwin,D., Yuan,J., Gurney,A., Goddard,A.D., Godowski,P. and
Ashkenazi,A.
TITLE A novel receptor for Apo2L/TRAIL contains a truncated death domain
JOURNAL Curr. Biol. 7 (12), 1003-1006 (1997)
PUBMED 9382840
REFERENCE 2 (bases 1 to 1726)
AUTHORS Marsters,S.A., Sheridan,J.P., Pitti,R.M., Huang,A., Skubatch,M.,
Baldwin,D., Yuan,J., Gurney,A., Goddard,A.D., Godowski,P. and
Ashkenazi,A.
TITLE Direct Submission
JOURNAL Submitted (14-OCT-1997) Molecular Oncology, Genentech, 1 DNA Way,
South San Francisco, CA 94080, USA
REFERENCE 3 (bases 1 to 1726)
AUTHORS Marsters,S.A., Sheridan,J.P., Pitti,R.M., Huang,A., Skubatch,M.,
Baldwin,D., Yuan,J., Gurney,A., Goddard,A.D., Godowski,P. and
Ashkenazi,A.
TITLE Direct Submission
JOURNAL Submitted (06-JAN-1999) Molecular Oncology, Genentech, 1 DNA Way,
South San Francisco, CA 94080, USA
REMARK Sequence update by submitter
COMMENT On Jan 6, 1999 this sequence version replaced gi:2688980.
FEATURES Location/Qualifiers
source 1..1726
/db_xref="H-InvDB:HIT000062991"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8p21"
CDS 83..1243
/function="inhibitory receptor for Apo2L/TRAIL"
/note="DcR2; member of the TNF receptor superfamily that
contains a truncated death domain"
/codon_start=1
/product="decoy receptor 2"
/protein_id="AAD03477.1"
/translation="MGLWGQSVPTASSARAGRYPGARTASGTRPWLLDPKILKFVVFI
VAVLLPVRVDSATIPRQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEG
VDYTIASNNLPSCLLCTVCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRT
GCPRGMVKVSNCTPRSDIKCKNESAASSTGKTPAAEETVTTILGMLASPYHYLIIIVV
LVIILAVVVVGFSCRKKFISYLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNAR
NETLSNRYLQPTQVSEQEIQGQELAELTGVTVESPEEPQRLLEQAEAEGCQRRRLLVP
VNDADSADISTLLDASATLEEGHAKETIQDQLVGSEKLFYEEDEAGSATSCL"
BASE COUNT 440 a 432 c 443 g 411 t
ORIGIN
1 cgagaacctt tgcacgcgca caaactacgg ggacgatttc tgattgattt ttggcgcttt
61 cgatccaccc tcctcccttc tcatgggact ttggggacaa agcgtcccga ccgcctcgag
121 cgctcgagca gggcgctatc caggagccag gacagcgtcg ggaaccagac catggctcct
181 ggaccccaag atccttaagt tcgtcgtctt catcgtcgcg gttctgctgc cggtccgggt
241 tgactctgcc accatccccc ggcaggacga agttccccag cagacagtgg ccccacagca
301 acagaggcgc agcctcaagg aggaggagtg tccagcagga tctcatagat cagaatatac
361 tggagcctgt aacccgtgca cagagggtgt ggattacacc attgcttcca acaatttgcc
421 ttcttgcctg ctatgtacag tttgtaaatc aggtcaaaca aataaaagtt cctgtaccac
481 gaccagagac accgtgtgtc agtgtgaaaa aggaagcttc caggataaaa actcccctga
541 gatgtgccgg acgtgtagaa cagggtgtcc cagagggatg gtcaaggtca gtaattgtac
601 gccccggagt gacatcaagt gcaaaaatga atcagctgcc agttccactg ggaaaacccc
661 agcagcggag gagacagtga ccaccatcct ggggatgctt gcctctccct atcactacct
721 tatcatcata gtggttttag tcatcatttt agctgtggtt gtggttggct tttcatgtcg
781 gaagaaattc atttcttacc tcaaaggcat ctgctcaggt ggtggaggag gtcccgaacg
841 tgtgcacaga gtccttttcc ggcggcgttc atgtccttca cgagttcctg gggcggagga
901 caatgcccgc aacgagaccc tgagtaacag atacttgcag cccacccagg tctctgagca
961 ggaaatccaa ggtcaggagc tggcagagct aacaggtgtg actgtagagt cgccagagga
1021 gccacagcgt ctgctggaac aggcagaagc tgaagggtgt cagaggagga ggctgctggt
1081 tccagtgaat gacgctgact ccgctgacat cagcaccttg ctggatgcct cggcaacact
1141 ggaagaagga catgcaaagg aaacaattca ggaccaactg gtgggctccg aaaagctctt
1201 ttatgaagaa gatgaggcag gctctgctac gtcctgcctg tgaaagaatc tcttcaggaa
1261 accagagctt ccctcattta ccttttctcc tacaaaggga agcagcctgg aagaaacagt
1321 ccagtacttg acccatgccc caacaaactc tactatccaa tatggggcag cttaccaatg
1381 gtcctagaac tttgttaacg cacttggagt aatttttatg aaatactgcg tgtgataagc
1441 aaacgggaga aatttatatc agattcttgg ctgcatagtt atacgattgt gtattaaggg
1501 tcgttttagg ccacatgcgg tggctcatgc ctgtaatccc agcactttga taggctgagg
1561 caggtggatt gcttgagctc gggagtttga gaccagcctc atcaacacag tgaaactcca
1621 tctcaattta aaaagaaaaa aagtggtttt aggatgtcat tctttgcagt tcttcatcat
1681 gagacaagtc tttttttctg cttcttatat tgcaagctcc atctct
//