LOCUS AF029231 5854 bp mRNA linear HUM 05-JAN-1999
DEFINITION Homo sapiens EXT homolog mRNA, complete cds.
ACCESSION AF029231
VERSION AF029231.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5854)
AUTHORS Deng,H.-X., Xu,L., Xia,J.-H., Fan,C., Pan,Q., Liu,C.-Y. and
Ruan,Q.-G.
TITLE Molecular cloning of a candidate gene for multiple exostoses
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 5854)
AUTHORS Deng,H.-X., Xu,L., Xia,J.-H., Fan,C., Pan,Q., Liu,C.-Y. and
Ruan,Q.-G.
TITLE Direct Submission
JOURNAL Submitted (07-OCT-1997) National Laboratory of Medical Genetics,
Hunan Medical University, 88 Xiangya Road, Changsha, Hunan 410078,
P.R. of China
FEATURES Location/Qualifiers
source 1..5854
/db_xref="H-InvDB:HIT000062958"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
CDS 263..3022
/note="candidate gene for multiple exostoses"
/codon_start=1
/product="EXT homolog"
/protein_id="AAD01877.1"
/translation="MTGYTMLRNGGAGNGGQTCMLRWSNRIRLTWLSFTLFVILVFFP
LIAHYYLTTLDEADEAGKRIFGPRVGNELCEVKHVLDLCRIRESVSEELLQLEAKRQE
LNSEIAKLNLKIEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLL
PEKDDAGLPPPKATRGCRLHNCFDYSRCPLTSGFPVYVYDSDQFVFGSYLDPLVKQAF
QATARANVYVTENADIACLYVILVGEMQEPVVLRPAELEKQLYSLPHWRTDGHNHVII
NLSRKSDTQNLLYNVSTGRAMVAQSTFYTVQYRPGFDLVVSPLVHAMSEPNFMEIPPQ
VPVKRKYLFTFQGEKIESLRSSLQEARSFEEEMEGDPPADYDDRIIATLKAVQDSKLD
QVLVEFTCKNQPKPSLPTEWALCGEREDRLELLKLSTFALIITPGDPRLVISSGCATR
LFEALEVGAVPVVLGEQVQLPYQDMLQWNEAALVVPKPRVTEVHFLLRSLSDSDLLAM
RRQGRFLWETYFSTADSIFNTVLAMIRTRIQIPAAPIREEAAAEIPHRSGKAAGTDPN
MADNGDLDLGPVETEPPYASPRYLRNFTLTVTDFYRSWNCAPGPFHLFPHTPFDPVLP
SEAKFLGSGTGFRPIGGGAGGSGKEFQAALGGNVPREQFTVVMLTYEREEVLMNSLER
LNGLPYLNKVVVVWNSPKLPSEDLLWPDIGVPIMVVRTEKNSLNNRFLPWNEIETEAI
LSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRYHAWDIPHQSWLYNSNYSCELSMV
LTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWT
FRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTK
CFKFI"
BASE COUNT 1204 a 1612 c 1610 g 1428 t
ORIGIN
1 ggcacctttt atcgtttgat aaagattaag gacatgttct ttggtcaaca gccagaactt
61 aaaatctgct ggaatagggt cagagaccat ttcagctgca gctgaggaaa atgaaatgtt
121 cattttattt ggtgccttgt ctggggagca cactaactct tctggaaacg tgtcagtgaa
181 acagagatcg ttttgtggaa tagcaaccca tggttatggc gagtgacccg acgtgatctg
241 gggggcaggc tgcagaggac tcatgacagg ctataccatg ctgcggaatg ggggcgcggg
301 gaacggaggt cagacctgca tgctgcgctg gtccaaccgc atccgcctca cgtggctcag
361 cttcacgctc tttgtcatcc tggtcttctt cccgctcatc gcccactatt acctcaccac
421 tctggatgag gctgatgagg caggcaagcg gatttttggt ccccgggtgg ggaacgagct
481 gtgcgaggtg aagcacgtgc tggatctgtg ccgcatccgg gagtcggtga gtgaagagct
541 cctgcagctg gaggccaagc gccaagagct gaacagcgag atcgccaagc tgaatctgaa
601 gatcgaagcc tgtaagaaga gcattgagaa cgccaagcag gacctgctcc agctcaagaa
661 tgtcatcagc cagaccgagc attcctacaa ggagctcatg gcccagaacc agcccaagct
721 gtccctgccc atccgactgc tcccagagaa ggacgatgcc ggcctccctc ccccgaaggc
781 cactcggggc tgccggctac acaactgctt tgattattct cgttgccctc tcacctctgg
841 cttcccggtc tacgtctatg acagtgacca gtttgtcttt ggcagctacc tggatccctt
901 ggtcaagcag gcttttcagg cgacagcacg agctaacgtt tatgttacag aaaatgcaga
961 catcgcctgc ctttacgtga tactagtggg agagatgcag gagccggtgg tgctgcggcc
1021 tgctgagctg gagaagcagt tgtattccct gccacactgg cggacggatg gacacaacca
1081 tgtcatcatc aatctgtcac gtaagtcaga tacacagaac cttctctata acgtcagtac
1141 tggccgtgcc atggtggccc agtccacctt ctacactgtc cagtacagac ctggctttga
1201 cttggtcgta tcaccgctgg tccatgccat gtctgagccc aacttcatgg aaatcccacc
1261 acaggtgccg gtgaagcgga aatatctctt caccttccag ggcgagaaga ttgagtctct
1321 gaggtctagc cttcaggagg cccgctcctt cgaagaggaa atggagggcg accctcccgc
1381 cgactacgat gaccggatca ttgccaccct gaaggcggtg caggacagca agctggatca
1441 ggtcctggtg gaattcacct gcaaaaacca gcccaaaccc agcctgccaa ctgagtgggc
1501 actgtgtgga gagcgggagg accgcttgga attgctgaag ctctccacct tcgccctcat
1561 cattaccccc ggggaccctc gcttggttat ttcctctggg tgtgcaacac ggctcttcga
1621 agccctggaa gtcggtgccg tcccggtggt gctgggggag caggtccagc ttccctacca
1681 ggacatgctg cagtggaacg aggcggccct ggtggtgcca aagcctcgtg ttaccgaggt
1741 tcatttcctg ctcagaagcc tctccgatag tgacctcctg gctatgaggc ggcaaggccg
1801 ctttctctgg gagacttact tctccactgc tgacagtatt tttaataccg tgctggctat
1861 gattaggact cgcatccaga tcccagccgc tcccatccgg gaagaggcgg cagctgagat
1921 cccccaccgt tcaggcaagg cggctggaac tgaccccaac atggctgaca acggggacct
1981 ggacctgggg ccagtggaga cggagccgcc ctacgcctca cccagatacc tccgcaattt
2041 cactctgact gtcactgact tttaccgcag ctggaactgt gctccagggc ctttccatct
2101 tttcccccac actccctttg accctgtgtt gccctcagag gccaaattct tgggctcagg
2161 gactggcttt cggcctattg gtggtggagc tgggggttct ggcaaggaat ttcaggcagc
2221 gcttggaggc aatgttcccc gagagcagtt cacggtggtg atgttgactt atgagcggga
2281 ggaagtgctt atgaactctt tagagaggct gaatggcctc ccttacctga acaaggtcgt
2341 ggtggtgtgg aattctccca agctgccatc agaggacctt ctgtggcctg acattggcgt
2401 ccccatcatg gtggtccgta ctgagaagaa cagtttgaac aaccgattct taccctggaa
2461 tgaaattgag acagaggcca tcctgtccat tgatgacgat gctcacctcc gccatgacga
2521 aatcatgttt gggttccggg tgtggagaga agctcgggac cgcatcgtgg gcttccctgg
2581 ccgttaccac gcatgggaca tcccccatca gtcctggctc tacaactcca actactcctg
2641 tgagctgtcc atggtgctga caggtgctgc cttctttcac aagtattatg cctacctgta
2701 ttcttatgtg atgccccagg ccatccggga catggtggat gaatacatca actgtgagga
2761 cattgccatg aacttccttg tctcccacat cactcggaag ccccccatca aggtgacctc
2821 acggtggaca ttccgatgcc caggatgccc tcaggccctg tctcatgatg actcccactt
2881 ccacgagcgg cacaagtgca tcaacttctt cgtgaaggtg tacggctaca tgcccctcct
2941 gtacacgcag ttcagggtgg attctgtgct cttcaagaca cgcctgcccc atgacaagac
3001 caagtgcttc aagttcatct aggggcagcg cacggtctgg ggaagaggat gagcagaggg
3061 aggaagatgg ctcccaaggt tcctaggcat tgcaggacct tgggcacatc tgctggtggg
3121 tggcccagag cctctgctgg aaggggcagc aggaggagtg gaaggaaacc gctgccttta
3181 tcttgaagtc agccacactg ggcctggagc cctgggcgga gtccccgggg ttccccacac
3241 agggcactga ctgatagctt acactgagga ctgtggcgac tctgcagagt cactcacacc
3301 gttcgtacgc ccaggacagc tggttcgtgg tttttacatt caataacaac tattatgatt
3361 atttaaaaag agaaagtttc agatttgcca ttcaaggctt atttatatat atgtgtgtgt
3421 atataaatac atgcacacac ttgcatacat atatattttt ggctggggga gtgtgagttt
3481 tgcctttcta agggagggac cgcgcaggct cctttgttct gtattctggc ggagatgggt
3541 cctggccttg tgtcactggc ttatccttaa agatcatctc ccatcctccc cagcgccatc
3601 tgtgtgcagc aaccagaaag ggatgaactt ggccctcttg cgggcctgga caaggtctct
3661 tccttaccct ttctgttgcc agtcagcaac ctgtaactca cattctcttc ccagtgaatc
3721 cctgggagcg cctgaccctg gtgggctgtt cagcttcctg ctgctggggc cagcgatttt
3781 tgaggattta tctttaggcc aggcttgcct ccgtacttat ccctgctctc ccatttctct
3841 cttgtttgag agagaatgag gaagcaaaga gtgagaaaga ataggggctg aagacgccac
3901 tcccagatgg ctctttctat cctgctcttc tgttgaaaca cacgtgctgt gggcctcagg
3961 cgtttctgaa gtgctctttc ttggattgga caggagatca gcagcgtgca catctgctgt
4021 ggtctgaagt ggtttgcagg tcagcctcct ctccctagtg tagagcaagc cagtgtcctt
4081 cgaggaaccc acccggctgg ccgggaagtt ttacagcaag gcgcctgcct tgggataatt
4141 ccttggtgaa attcaccttc cccccgcctc tgtctggagc cccatcctgt gttatctgtg
4201 gtttttggac ccctaatgtc agcttggctg taggactccc cgaggtttgg tatgtgctag
4261 aacaatggga ggctgtgatt tgctgtgtaa gctcacatcc agccttggaa tctaacgggc
4321 attcacaacc cgagttacca ctttccactc cctgcttagg attctgttcc ctgggctgaa
4381 actgaaataa gctaattttt tgggtcatgg tggcagtagg ggaacctagg agggtgtgag
4441 tggcatttgt cagggattta gcccatgacg tgtttcttga accctacttt ctggaagtgg
4501 agttgactct ggaagttttc tagcaactga acaaaagctc aggtttgtcc tggtcatgca
4561 catgccttaa gccagttccg tcttccctag accttggcat cctgtgcttc tatttcttgg
4621 aatacgttct cctctgacct gcctgtacca cgtgggtcct cttcaagtac tgttttgaag
4681 ctgggctctt ttgtgtagct cccacccacc tgtagggcta gctcggctta agggaactct
4741 ccccattggc aaaccggacc cggccgccgc caggactgtg tttccaaagg ttccccgccc
4801 ccaaccccag catcagcctg tagctcccct gctgaggcag tgtggttatg ttcccagcag
4861 tgggggtcag acgcccttcc tcagaacttt ctagttgccc tctacctgac tcctgacttg
4921 tattcctttt agcagtagcc ttcttccctc ggggagccaa agagtgtggt gtgtggcgct
4981 atattgtggc tgctatttca tctggtttct tttaatgtga ggaactcaca tactgacttc
5041 agtgggactc ggtgagccgg ggccgtctgt gtggtgggac cccctttagc gggactcagt
5101 gagctggggc cgtctgtgtg gtggagccag ggcctctccc tttagtggag ccaggttgtc
5161 gggccccgaa tgtcactggt ggatctaaga agggctgagt ggtctgacac caaaacatgc
5221 cgcagggagg gctgtggtgc cggtgcttcc aacaaggaca gccctccttg accctgaaag
5281 gaacactggc ttgaaggact gcagacaggc tctgaggggc acgccctcct cagcgagagg
5341 cagcaaggtg gccacagtgt cactggtcag gtgcttctca ccacgggaaa gccgccgacc
5401 tgtgactcgc ttgagatggg aaagcggcgc cacagacccc gggtctcctt ggctgtctgt
5461 gggccgcccc tggccacctt gtcctggctc gcagggtgca ggagcgcctc gttctctggg
5521 tggccggctt gctgctccgg tttgggctgt cttaccataa caccgtccca gggctctgca
5581 ggccactgtg agcgctggct ccctgggcag tgctcctccg tgtggactgt gcctcaggcc
5641 agggctcacc agctggggtc ctgtccggaa ggatgggatc tttctgggag ctgcgccgga
5701 cagagtgggg agctcctagt ttgtgggggg aagctttgat atccatgcca cgtccatcca
5761 ccccacccct tttcgtcacg agcacaatgg tcttacattg gatttttgta aaaaaataaa
5821 aataaatgga gactttaact caaaaaaaaa aaaa
//