LOCUS AF029106 3753 bp mRNA linear HUM 16-OCT-2000
DEFINITION Homo sapiens Mint1 mRNA, complete cds.
ACCESSION AF029106
VERSION AF029106.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3753)
AUTHORS Okamoto,M. and Sudhof,T.C.
TITLE Mints, Munc18-interacting proteins in synaptic vesicle exocytosis
JOURNAL J. Biol. Chem. 272 (50), 31459-31464 (1997)
PUBMED 9395480
REFERENCE 2 (bases 1 to 3753)
AUTHORS Okamoto,M. and Sudhof,T.C.
TITLE Direct Submission
JOURNAL Submitted (06-OCT-1997) Dept. of Molecular Genetics, UT
Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX
75235, USA
FEATURES Location/Qualifiers
source 1..3753
/db_xref="H-InvDB:HIT000062952"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
gene 1..3753
/gene="mint 1"
CDS 199..2712
/gene="mint 1"
/function="putative function in synaptic vesicle
exocytosis by binding to munc18-1, an essential component
of the synaptic vesicle exocytotic machinery"
/note="contains PDZ and PTB domains but no transmembrane
region; neuronal munc18-1 binding protein"
/codon_start=1
/product="Mint1"
/protein_id="AAC05304.1"
/translation="MNHLEGSAEVEVTDEAAGGEVNESVEADLEHPEVEEEQQQPPQQ
QHYVGRHQRGRALEDLRAQLGQEEEERGECLARSASTESGFHNHTDTAEGDVIAAARD
GYDAERAQDPEDESAYAVQYRPEAEEYTEQAEAEHAEATHRRALPNHLHFHSLEHEEA
MNAAYSGYVYTHRLFHRGEDEPYSEPYADYGGLQEHVYEEIGDAPELHARDGLRLYEQ
ERDEAAAYRQEALGARLHHYDERSDGESDSPEKEAEFAPYPRMDSYEQEEDIDQIVAE
VKQSMSSQSLDKAAEDMPEAEQDLERPPTPAGGRPDSPGLQAPAGQQRAVGPAGGGEA
GQRYSKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCD
DQRPMDGDSPSPGSSSPLGAESSSTSLHPSDPVEVPINKESRKSLASFPTYVEVPGPC
DPEDLIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKMAQKLAKSRKKAPE
GESQPMTEVDLFILTQRIKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRIPRS
NSQENVEASHPSQDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPE
DLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPT
VIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLENQSRVKLNIV
RCPPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVA
TPHEKIVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI"
BASE COUNT 853 a 1125 c 1082 g 693 t
ORIGIN
1 gcggcgggag aagatggtgg cgctggaggc agcagcggct ggagcggagc tttattccca
61 ggcttggcac cagcgctgtc actagcgccg cctgctcccg cgggcccgcg gacccagctg
121 tcaggcaagc ccagtggagc aaaatgagag cgcagtgagc cgggcccagc ttctctccta
181 gccgttccga ctcccaccat gaaccacttg gaggggtctg cggaggtgga ggtgaccgac
241 gaggcggcag gtggggaggt gaacgagtcg gtggaggccg acctggagca ccccgaggtg
301 gaagaggaac agcagcagcc gccgcagcag cagcactatg tgggccgcca ccagcgcggg
361 cgagccctcg aggacctccg cgcccagctc ggccaggagg aagaggagcg cggggaatgc
421 ctggcgcgct cagccagcac ggagagcggc ttccacaacc acacggacac cgccgagggc
481 gacgtgatcg ccgcggcccg cgacggctac gatgcggagc gcgcgcagga ccccgaggac
541 gagagcgcct atgctgtgca gtaccggccc gaggccgagg agtacacgga gcaggcagag
601 gccgagcacg ccgaggccac gcaccgccgc gcgctgccca accacctgca cttccactcg
661 ctggagcacg aggaagccat gaatgcggcc tactcaggct acgtctacac gcaccggctc
721 ttccaccgcg gtgaggacga gccctactcc gagccctatg ccgactacgg cggcctccag
781 gagcacgtgt acgaggagat aggggacgcg cccgagctgc acgcacgcga cggtctgcgg
841 ctctacgagc aggagcgcga cgaggcggcc gcgtaccgcc aggaggccct gggcgcgcgg
901 ctgcaccatt acgacgagcg ctccgacggc gagtccgaca gccccgagaa ggaggccgag
961 ttcgcgccct acccgcgcat ggacagctac gagcaggagg aggacatcga ccagatagtg
1021 gccgaggtga agcagagcat gagctcgcag agcctcgaca aggcagccga ggacatgcct
1081 gaggccgagc aggacctgga gcgtccccct accccggccg ggggtcgccc cgacagcccc
1141 gggctgcagg cgccggcggg gcagcagcgg gcggtgggcc ccgcgggcgg cggcgaggcg
1201 gggcagcggt acagcaagga gaagcgcgat gccatctcgc tggccatcaa ggacatcaag
1261 gaggccatcg aggaggtgaa aaccaggacc atccgttcgc cttacacccc cgacgagccc
1321 aaagagccca tctgggtcat gcgccaggac attagcccca ccagggactg tgacgaccag
1381 aggccgatgg acggagattc tccgtctcct ggcagctcct cccccttggg tgcagagtca
1441 tcaagcacat ctcttcaccc cagtgaccct gtggaagtgc ccattaataa agagtcaaga
1501 aaaagcttgg cttcattccc aacctacgtt gaagttccgg gaccctgcga ccccgaagac
1561 ttgatcgatg gaatcatttt tgccgccaat taccttggct ccactcagct gctctcagac
1621 aaaactcctt ccaaaaacgt gcgcatgatg caggcccagg aagccgtaag caggatcaag
1681 atggcccaga aattagccaa aagcaggaag aaggctcctg aaggcgaatc tcagccaatg
1741 actgaagtgg acctcttcat tcttacccag agaatcaaag tgctgaacgc cgacacacag
1801 gagacaatga tggaccaccc tctgaggacc atttcctaca ttgcggacat tgggaacatc
1861 gttgtgctga tggcccgccg gcggatacct cgctccaact cccaggagaa cgtggaagcg
1921 tcccacccat cccaggatgg gaaaaggcag tacaagatga tctgccacgt cttcgagtct
1981 gaggatgctc agctgattgc acagtccatc ggacaggcat ttagcgtggc ataccaggaa
2041 ttcctcaggg ccaatgggat taaccccgaa gatctcagcc agaaggagta tagtgacctg
2101 ctcaataccc aggacatgta caacgatgac ctgatccact tctccaagtc ggaaaactgt
2161 aaagatgttt tcatagagaa gcagaaagga gaaatcctag gtgtggtgat tgtggagtct
2221 ggctggggat ccatcctccc caccgtgatc attgccaaca tgatgcatgg tggccctgcg
2281 gagaaatctg ggaagctgaa tatcggtgac cagatcatgt ccattaatgg caccagcctg
2341 gtgggcctgc ctctgtccac ctgccagagc attattaagg gcttagagaa tcagtcccga
2401 gtcaagctga atatcgtgag atgtcctccg gtgaccaccg tgttaatcag aagaccagac
2461 cttcgctacc agctcggttt cagcgtccag aatggaatta tctgcagcct catgcgaggg
2521 ggaatagctg agagaggagg cgtccgtgtg gggcaccgga tcattgaaat caatggacag
2581 agcgtcgtgg ccacccccca cgagaagatc gtccacattc tctccaatgc tgttggggag
2641 attcatatga agacaatgcc agccgcgatg tacaggctgc tgacggccca ggagcagcct
2701 gtttacatct gaccgcggcc acacgcggtg gcatgcatgg aggactctcc tcttcgtggt
2761 tgtgtttctc gtgctgcatc cctgtgtcca ctgagacttt cccctctcgc gcccagcatt
2821 tggttttaca caggaagaga agaatccaca aggacctctt tactctctcc gatttgcttt
2881 tttttttttt ttttttcaat accagggaag tttcgtatgc actcccttga ggatggagag
2941 cagccagcac ccacctggta ctgacccagg accatcctgg agggctttct gggtgtgtcc
3001 agggggtggg ctgtcactgc ttgagggaga atcctccctt cccaggaggt gcagacttct
3061 taaaaggagc tcgcggggca gcaaagcagc tgattcagca gtgcctaaaa cccagttgct
3121 gatccctgct ctctgagttt atctgtggga atgtggtagt acccagggcc agcccacgtc
3181 attaaggtta tgcactgcct gccatgtagt tggggcacca tacattattt cttcccagaa
3241 tctctgagcc aaccttaaac ctcttctatt gctagttcta atttcaacgt atgtgtgttt
3301 tctaatacga gccttctcac cccaggataa aaggggaaat aactgccttg ggcaaggaca
3361 ccatagtgtc acagagagct tggcaattca tggggcatct gaagctttac caggttgtcc
3421 tcaagttatc aaccattaga taaacacagg caggtactgt ctgcttctct ctctctcaca
3481 cacacacaca cacacacagt cccattcgga tatcaccctt ccctgctccc accaccagtg
3541 agacaagctg aagattaggc acacagatcc cctggaaacc cacctctctg gaaggtccct
3601 tccctggcag gtggtcaggc aggcgggggc tgttcagcct catcctgaga gacctgtcct
3661 ctctgtgctg aggtccagcc cctccagcac cactttggct tatcgtatcc tcctcctgga
3721 cttaccctct ctgccgaaca cacatcccag gcg
//