LOCUS AF027866 2249 bp mRNA linear HUM 20-OCT-1998
DEFINITION Homo sapiens megsin mRNA, complete cds.
ACCESSION AF027866
VERSION AF027866.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2249)
AUTHORS Miyata,T., Nangaku,M., Suzuki,D., Inagi,R., Uragami,K., Sakai,H.,
Okubo,K. and Kurokawa,K.
TITLE A mesangium-predominant gene, megsin, is a new serpin upregulated
in IgA nephropathy
JOURNAL J. Clin. Invest. 102 (4), 828-836 (1998)
PUBMED 9710452
REFERENCE 2 (bases 1 to 2249)
AUTHORS Toshio,M., Yasuda,Y., Nangaku,M. and Kurokawa,K.
TITLE Direct Submission
JOURNAL Submitted (02-OCT-1997) Medical Science, Tokai University,
Bouseidai, Isehara, Kanagawa 259-11, Japan
REFERENCE 3 (bases 1 to 2249)
AUTHORS Toshio,M., Yasuda,Y., Nangaku,M. and Kurokawa,K.
TITLE Direct Submission
JOURNAL Submitted (19-OCT-1998) Medical Science, Tokai University,
Bouseidai, Isehara, Kanagawa 259-11, Japan
REMARK Sequence update by submitter
COMMENT On Oct 20, 1998 this sequence version replaced gi:3764058.
FEATURES Location/Qualifiers
source 1..2249
/db_xref="H-InvDB:HIT000062896"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="mesangial"
CDS 365..1507
/codon_start=1
/product="megsin"
/protein_id="AAC64506.1"
/translation="MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRL
GAQDDSLSQIDKLLHVNTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGL
FAEKVYGFHKDYIECAEKLYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGE
GGISSSAVMVLVNAVYFKGKWQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSV
IEDPSMKILELRYNGGINMYVLLPENDLSEIENKLTFQNLMEWTNPRRMTSKYVEVFF
PQFKIEKNYEMKQYLRALGLKDIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGT
EATAATGSNIVEKQLPQSTLFRADHPFLFVIRKDDIILFSGKVSCP"
BASE COUNT 649 a 452 c 461 g 683 t
ORIGIN
1 gtctacttat caataagcag ctgcctgtgc agagtgcagg ctgcaccttt ggacagcctt
61 taaaactgaa ttctcagaat tttagaacaa atttttgtct agaaatgctg actttggttc
121 attaggtagt ggtaaaacag gctcccttcg aagctctcct tcatcacctt cctaagtgca
181 tgtacaggga agctctcctt catcaccttc ctaagtgcat gggggaaaat acctagggct
241 caacagtctt gagaagtgtg gaaacatttt ctttgtgagt gagaacagat cacctagaga
301 aaggaaacca gattcccatc actgcttctg ggtatcagat gctagcgctg cactccattt
361 tgcaatggcc tcccttgctg cagcaaatgc agagttttgc ttcaacctgt tcagagagat
421 ggatgacaat caaggaaatg gaaatgtgtt cttttcctct ctgagcctct tcgctgccct
481 ggccctggtc cgcttgggcg ctcaagatga ctccctctct cagattgata agttgcttca
541 tgttaacact gcctcaggat atggaaactc ttctaatagt cagtcagggc tccagtctca
601 actgaaaaga gttttttctg atataaatgc atcccacaag gattatgatc tcagcattgt
661 gaatgggctt tttgctgaaa aagtgtatgg ctttcataag gactacattg agtgtgccga
721 aaaattatac gatgccaaag tggagcgagt tgactttacg aatcatttag aagacactag
781 acgtaatatt aataagtggg ttgaaaatga aacacatggc aaaatcaaga acgtgattgg
841 tgaaggtggc ataagctcat ctgctgtaat ggtgctggtg aatgctgtgt acttcaaagg
901 caagtggcaa tcagccttca ccaagagcga aaccataaat tgccatttca aatctcccaa
961 gtgctctggg aaggcagtcg ccatgatgca tcaggaacgg aagttcaatt tgtctgttat
1021 tgaggaccca tcaatgaaga ttcttgagct cagatacaat ggtggcataa acatgtacgt
1081 tctgctgcct gagaatgacc tctctgaaat tgaaaacaaa ctgacctttc agaatctaat
1141 ggaatggacc aatccaaggc gaatgacctc taagtatgtt gaggtatttt ttcctcagtt
1201 caagatagag aagaattatg aaatgaaaca atatttgaga gccctagggc tgaaagatat
1261 ctttgatgaa tccaaagcag atctctctgg gattgcttcg gggggtcgtc tgtatatatc
1321 aaggatgatg cacaaatctt acatagaggt cactgaggag ggcaccgagg ctactgctgc
1381 cacaggaagt aatattgtag aaaagcaact ccctcagtcc acgctgttta gagctgacca
1441 cccattccta tttgttatca ggaaggatga catcatctta ttcagtggca aagtttcttg
1501 cccttgaaaa tccaattggt ttctgttata gcagtcccca caacatcaaa graccaccac
1561 aagtcaatag atytgrgttt aattggaaaa atgtggtgtt tcctttgagt ttatttcttc
1621 ctaacattgg tcagcagatg acactggtga cttgaccctt cctagacacc tggttgattg
1681 tcctgatccc tgctcttagc attctaccac catgtgtctc acccatttct aatttcattg
1741 tctttcttcc cacgctcatt tctatcattc tcccccatga cccgtctgga aattatggag
1801 rgtgctcaac tggtaaggag aacgtagaag tagccctagg gatccttttt gaaactctac
1861 agttatcgca gatattctag cttcattgta agcaatctag gaaataagcc ctgctgcttt
1921 ctagaaataa gtgtgaagga taaattttct ttgttgacct atgaagattt tagagtttac
1981 cttcatatgt ttgattttaa atcagtgtat aatctagatg gtaaaaaatg tgaaattggg
2041 attagggacc taccaaaata tttcattaat gctttcaatt gacaaatttt ggcctttctt
2101 tgataagaca atatgtacat gttttttcaa atattaaaga tcttttaact gttggcagtt
2161 gttatctaca gaatcatatt tcatatgctg tgtagtttat aagtttttcc tctatttatc
2221 agaataaaga aatacaacat acctgtaaa
//