LOCUS AF026548 1890 bp mRNA linear HUM 03-NOV-1997
DEFINITION Homo sapiens branched chain alpha-ketoacid dehydrogenase kinase
precursor, mRNA, nuclear gene encoding mitochondrial protein,
complete cds.
ACCESSION AF026548
VERSION AF026548.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1890)
AUTHORS Chuang,J.C., Cox,R.P. and Chuang,D.T.
TITLE Direct Submission
JOURNAL Submitted (24-SEP-1997) Biochemistry, UT Southwestern Medical
Center, 5323 Harry Hines Blvd, Dallas, Tx 75235, USA
FEATURES Location/Qualifiers
source 1..1890
/db_xref="H-InvDB:HIT000062828"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 274..1512
/note="BCKD kinase"
/codon_start=1
/product="branched chain alpha-ketoacid dehydrogenase
kinase precursor"
/protein_id="AAB82714.1"
/translation="MILASVLRSGPGGGLPLRPLLGPALALRARSTSATDTHHVEMAR
ERSKTVTSFYNQSAIDAAAEKPSVRLTPTMMLYAGRSQDGSHLLKSARYLQQELPVRI
AHRIKGFRCLPFIIGCNPTILHVHELYIRAFQKLTDFPPIKDQADEAQYCQLVRQLLD
DHKDVVTLLAEGLRESRKHIEDEKLVRYFLDKTLTSRLGIRMLATHHLALHEDKPDFF
GIICTRLSPKKIIEKWVDFARRLCEHKYGNAPRVRINGHVAARFPFIPMPLDYILPEL
LKNAMRATMESHLDTPYNVPDVVITIANNDVDLIIRISDRGGGIAHKDLDRVMDYHFT
TAEASTQDPRISPLFGHLDMHSGAQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSLQGI
GTDVYLRLRHIDGREESFRI"
transit_peptide 274..363
/note="mitochondrial targeting sequence"
mat_peptide 364..1509
/product="branched chain alpha-ketoacid dehydrogenase
kinase"
polyA_site 1848
BASE COUNT 396 a 613 c 518 g 363 t
ORIGIN
1 atctgtcgac tgctaccggg cgcaggcggc tgggacaatg gcggtggact gttcgagccc
61 ttccgctggg acccgggccc tggctccggc cccgcgatgg gagctgctct ccgcgggctg
121 agcctgtcag catcctcgac gcaccctggt ccctgaagtc ggagaagcgc ccctacccac
181 ccacaccccc ttgccccatt ttgggtcgcc tgggtcctca gtcctagcgg atcctcagtc
241 ctagcggcca ccgggtctga aaggagcaag acgatgatcc tggcgtcggt gctgaggagc
301 ggtcccgggg gcgggcttcc gctccggccc ctcctgggac ccgcactcgc gctccgggcc
361 cgctcgacgt cggccaccga cacacaccac gtggagatgg ctcgggagcg ctccaagacc
421 gtcacctcct tttacaacca gtcggccatc gacgcggcag cggagaagcc ctcagtccgc
481 ctaacgccca ccatgatgct ctacgctggc cgctctcagg acggcagcca ccttctgaaa
541 agtgctcggt acctgcagca agaacttcca gtgaggattg ctcaccgcat caagggcttc
601 cgctgccttc ctttcatcat tggctgcaac cccaccatac tgcacgtgca tgagctatat
661 atccgtgcct tccagaagct gacagacttc cctccgatca aggaccaggc ggacgaggcc
721 cagtactgcc agctggtgcg acagctgctg gatgaccaca aggatgtggt gaccctcttg
781 gcagagggcc tacgtgagag ccggaagcac atagaggatg aaaagctcgt ccgctacttc
841 ttggacaaga cgctgacttc gaggcttgga atccgcatgt tggccacgca tcacctggcg
901 ctgcatgagg acaagcctga ctttttcggc atcatctgta ctcgtctctc accaaagaag
961 attattgaga agtgggtgga ctttgccaga cgcctgtgtg agcacaagta tggcaatgcg
1021 ccccgtgtcc gcatcaatgg ccatgtggct gcccggttcc ccttcatccc tatgccactg
1081 gactacatcc tgccggagct gctcaagaat gccatgagag ccacaatgga gagtcaccta
1141 gacactccct acaatgtccc agatgtggtc atcaccatcg ccaacaatga tgtcgatctg
1201 atcatcagga tctcagaccg tggtggagga atcgctcaca aagatctgga ccgggtcatg
1261 gactaccact tcactactgc tgaggccagc acacaggacc cccggatcag ccccctcttt
1321 ggccatctgg acatgcatag tggcgcccag tcaggaccca tgcacggctt tggcttcggg
1381 ttgcccacgt cacgggccta cgcggagtac ctcggtgggt ctctgcagct gcagtccctg
1441 cagggcattg gcacggacgt ctacctgcgg ctccgccaca tcgatggccg ggaggaaagc
1501 ttccggatct gaccccacag cctttggcct gctcacccga ccagcctggg ccgcattccc
1561 tgcaggacct cccgggtcag gcagggcggc cccctgctac cacacactgc tgcatcttgg
1621 gtctcaggga cccagacaga tggacttaca tggagctggg cactgccctg cctcaacagg
1681 gtccattgcc tcttgcctcc agaacttgga gagcagggaa gtgggcaccc ttgaggcctc
1741 cagcaccagt tccgtcattc tcgttcctgg ggaaccccca ctctgacctg ttattaaagt
1801 tcacattttg aatgccctct cgggccccgt gtgtggggag ggcaggtgaa aaaaaaaaaa
1861 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//