LOCUS AF026273 1782 bp mRNA linear HUM 01-DEC-1997
DEFINITION Homo sapiens interleukin-1 receptor-associated kinase-2 mRNA,
complete cds.
ACCESSION AF026273
VERSION AF026273.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1782)
AUTHORS Muzio,M., Ni,J., Feng,P. and Dixit,V.M.
TITLE A novel IRAK/Pelle family member and MyD88 are components of the
IL-1R signaling complex
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1782)
AUTHORS Muzio,M., Ni,J., Feng,P. and Dixit,V.M.
TITLE Direct Submission
JOURNAL Submitted (22-SEP-1997) Pathology, University of Michigan, 1150
Med. Ctr. Drive, MSRBI, Room 7210, Ann Arbor, MI 48109, USA
FEATURES Location/Qualifiers
source 1..1782
/db_xref="H-InvDB:HIT000062813"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 10..1782
/note="a novel IRAK/Pelle family member; IRAK-2"
/codon_start=1
/product="interleukin-1 receptor-associated kinase-2"
/protein_id="AAB87669.1"
/translation="MACYIYQLPSWVLDDLCRNMDALSEWDWMEFASYVITDLTQLRK
IKSMERVQGVSITRELLWWWGMRQATVQQLVDLLCRLELYRAAQIILNWKPAPEIRCP
IPAFPDSVKPEKPLAASVRKAEDEQEEGQPVRMATFPGPGSSPARAHQPAFLQPPEED
APHSLRSDLPTSSDSKDFSTSIPKQEKLLSLAGDSLFWSEADVVQATDDFNQNRKISQ
GTFADVYRGHRHGKPFVFKKLRETACSSPGSIERFFQAELQICLRCCHPNVLPVLGFC
AARQFHSFIYPYMANGSLQDRLQGQGGSDPLPWPQRVSICSGLLCAVEYLHGLEIIHS
NVKSSNVLLDQNLTPKLAHPMAHLCPVNKRSKYTMMKTHLLRTSAAYLPEDFIRVGQL
TKRVDIFSCGIVLAEVLTGIPAMDNNRSPVYLKDLLLSEIPSSTASLCSRKTGVENVM
AKEICQKYLEKGAGRLPEDCAEALATAACLCLRRRNTSLQEVCGSVAAVEERLRGRET
LLPWSGLSEGTGSSSNTPEETDDVDNSSLDASSSMSVAPWAGAATPLLPTENGEGRLR
VIVGREADSSSEACVGLEPPQDVT"
BASE COUNT 388 a 520 c 510 g 363 t
ORIGIN
1 tagcgtgcca tggcctgcta catctaccag ctgccctcct gggtgctgga cgacctgtgc
61 cgcaacatgg acgcgctcag cgagtgggac tggatggagt tcgcctccta cgtgatcaca
121 gacctgaccc agctgcggaa gatcaagtcc atggagcggg tgcagggtgt gagcatcacg
181 cgggagctgc tgtggtggtg gggcatgcgg caggccaccg tccagcaact tgtggacctc
241 ctgtgccgcc tggagctsta ccgggctgcc cagatcatcc tgaactggaa accggctcct
301 gaaatcaggt gtcccattcc agccttccct gactctgtga agccagaaaa gcctttggca
361 gcttctgtaa gaaaggctga ggatgaacag gaagaggggc agcctgtgag gatggccacc
421 tttccaggcc cagggtcctc tccagccaga gcccaccagc cggcctttct ccagcctcct
481 gaagaagatg cccctcattc cttgagaagc gacctcccca cttcgtctga ttcaaaggac
541 ttcagcacct ccattcctaa gcaggaaaaa cttttgagct tggctggaga cagccttttc
601 tggagtgagg cagacgtggt ccaggcaacc gatgacttca atcaaaaccg caaaatcagc
661 caggggacct ttgctgacgt ctacagaggg cacaggcacg ggaagccatt cgtcttcaag
721 aagctcagag agacagcctg ttcaagtcca ggatcaatcg aaagattctt ccaggcagag
781 ttgcagattt gtcttagatg ctgccacccc aatgtcttac ctgtgctggg cttctgtgct
841 gcaagacagt ttcacagctt catctacccc tacatggcaa atggttccct acaggacaga
901 ctgcagggtc agggtggctc ggaccccctc ccctggcccc agcgtgtcag catctgctca
961 gggctgctct gtgccgtcga gtacctgcat ggtctggaga tcatccacag caacgtcaag
1021 agctctaatg tcttgctgga ccaaaatctc acccccaaac ttgctcaccc aatggctcat
1081 ctgtgtcctg tcaacaaaag gtcaaaatac accatgatga agactcacct gctccggacg
1141 tcagccgcgt atctgccaga ggatttcatc cgggtggggc agctgacaaa gcgagtggac
1201 atcttcagct gtggaatagt gttggccgag gtcctcacgg gcatccctgc aatggataac
1261 aaccgaagcc cggtttacct gaaggactta ctcctcagtg aaattccaag cagcaccgcc
1321 tcgctctgct ccaggaagac gggcgtggag aacgtgatgg caaaggagat ctgccagaag
1381 tacctggaga agggcgcagg gaggcttccg gaggactgcg ccgaggccct ggccacggct
1441 gcctgcctgt gcctgcggag gcgtaacacc agcctgcagg aggtgtgtgg ctctgtggct
1501 gctgtggaag agcggctccg aggtcgggag acgttgctcc cttggagtgg gctttctgag
1561 ggtacaggct cttcttccaa caccccagag gaaacagacg acgttgacaa ttccagcctt
1621 gatgcctcct cctccatgag tgtggcaccc tgggcagggg ctgccacccc acttctcccc
1681 acagagaatg gggaaggaag gctgcgggtc atcgtgggaa gggaggctga ctcctcctct
1741 gaggcctgtg ttggcctgga gcctccccag gatgttacat aa
//