LOCUS AF026070 1669 bp mRNA linear HUM 28-JAN-1998
DEFINITION Homo sapiens death receptor 3 beta (DR3) mRNA, complete cds.
ACCESSION AF026070
VERSION AF026070.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1669)
AUTHORS Warzocha,K., Ribeiro,P., Charlot,C., Renard,N., Coiffier,B. and
Salles,G.
TITLE A new death receptor 3 isoform: expression in human lymphoid cell
lines and non-Hodgkin's lymphomas
JOURNAL Biochem. Biophys. Res. Commun. 242 (2), 376-379 (1998)
PUBMED 9446802
REFERENCE 2 (bases 1 to 1669)
AUTHORS Warzocha,K., Ribeiro,P., Renard,N., Charlot,C., Coiffier,B. and
Salles,G.
TITLE Direct Submission
JOURNAL Submitted (19-SEP-1997) Hematology, CTRE Hospitalier Lyon-Sud,
Chemin du Grand Revoyet, Pierre Benite 69495, France
FEATURES Location/Qualifiers
source 1..1669
/db_xref="H-InvDB:HIT000062796"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Mieliki"
/note="identified in human pre-B cell line Mieliki and in
patients with non-Hodgkin's lymphoma"
gene 1..1669
/gene="DR3"
/gene_synonym="Apo-3"
/gene_synonym="LARD"
/gene_synonym="TRAMP"
CDS 69..1349
/gene="DR3"
/gene_synonym="Apo-3"
/gene_synonym="LARD"
/gene_synonym="TRAMP"
/note="DR3 beta; TNF receptor family member; alternatively
spliced product; contains 28 amino-acid extension to the
extracellular domain of the ordinary DR3 molecule"
/codon_start=1
/product="death receptor 3 beta"
/protein_id="AAC39556.1"
/translation="MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIG
LFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQV
ALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDT
DCGTCLPGFYEHGDGCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAG
LVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDS
SEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPARAPTLSPESPAGSP
AMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGLFRDQQYEMLKHWR
QQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP"
BASE COUNT 329 a 532 c 513 g 295 t
ORIGIN
1 ctgaaggcgg aaccacgacg ggcagagagc acggagccgg gaagcccctg ggcgcccgtc
61 ggagggctat ggagcagcgg ccgcggggct gcgcggcggt ggcggcggcg ctcctcctgg
121 tgctgctggg ggcccgggcc cagggcggca ctcgtagccc caggtgtgac tgtgccggtg
181 acttccacaa gaagattggt ctgttttgtt gcagaggctg cccagcgggg cactacctga
241 aggccccttg cacggagccc tgcggcaact ccacctgcct tgtgtgtccc caagacacct
301 tcttggcctg ggagaaccac cataattctg aatgtgcccg ctgccaggcc tgtgatgagc
361 aggcctccca ggtggcgctg gagaactgtt cagcagtggc cgacacccgc tgtggctgta
421 agccaggctg gtttgtggag tgccaggtca gccaatgtgt cagcagttca cccttctact
481 gccaaccatg cctagactgc ggggccctgc accgccacac acggctactc tgttcccgca
541 gagatactga ctgtgggacc tgcctgcctg gcttctatga acatggcgat ggctgcgtgt
601 cctgccccac gccacccccg tcccttgcag gagcaccctg gggagctgtc cagagcgctg
661 tgccgctgtc tgtggctgga ggcagagtag gtgtgttctg ggtccaggtg ctcctggctg
721 gccttgtggt ccccctcctg cttggggcca ccctgaccta cacataccgc cactgctggc
781 ctcacaagcc cctggttact gcagatgaag ctgggatgga ggctctgacc ccaccaccgg
841 ccacccatct gtcacccttg gacagcgccc acacccttct agcacctcct gacagcagtg
901 agaagatctg caccgtccag ttggtgggta acagctggac ccctggctac cccgagaccc
961 aggaggcgct ctgcccgcag gtgacatggt cctgggacca gttgcccagc agagctcttg
1021 gccccgctcg tgcgcccaca ctctcgccag agtccccagc cggctcgcca gccatgatgc
1081 tgcagccggg cccgcagctc tacgacgtga tggacgcggt cccagcgcgg cgctggaagg
1141 agttcgtgcg cacgctgggg ctgcgcgagg cagagatcga agccgtggag gtggagatcg
1201 gtctcttccg agaccagcag tacgagatgc tcaagcactg gcgccagcag cagcccgcgg
1261 gcctcggagc cgtttacgcg gccctggagc gcatggggct ggacggctgc gtggaagact
1321 tgcgcagccg cctgcagcgt ggcccgtgac acgcagccca cttgccacct aggcgctctg
1381 gtggcccttg cagaagccct aagtacggtt acttatgcgt gtagacattt tatgtcactt
1441 attaagccgc tggcacggcc ctgcgtaggc acaccagccg gccccacccc tgctcgcccc
1501 tatcgctcca gccaaggcga agaagcacga acgaatgtcg agagggggtg aagacatttc
1561 tcaacttctc ggccggagtt tggctgagat cgcggtatta aatctgtgaa agaaataaag
1621 aaaaaaacaa aacaaaacaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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