LOCUS AF023456 3440 bp mRNA linear HUM 06-NOV-1997
DEFINITION Homo sapiens protein phosphatase with EF-hands-2 long form (PPEF-2)
mRNA, complete cds.
ACCESSION AF023456
VERSION AF023456.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3440)
AUTHORS Sherman,P.M., Sun,H., Macke,J.P., Williams,J., Smallwood,P.M. and
Nathans,J.
TITLE Identification and characterization of a conserved family of
protein serine/threonine phosphatases homologous to Drosophila
retinal degeneration C
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 94 (21), 11639-11644 (1997)
PUBMED 9326663
REFERENCE 2 (bases 1 to 3440)
AUTHORS Sherman,P.M., Sun,H., Macke,J.P., Williams,J., Smallwood,P.M. and
Nathans,J.
TITLE Direct Submission
JOURNAL Submitted (09-SEP-1997) Mol. Bio. & Gen., Johns Hopkins School of
Medicine/HHMI, 725 N. Wolfe St., Baltimore, MD 21205, USA
FEATURES Location/Qualifiers
source 1..3440
/db_xref="H-InvDB:HIT000062711"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/tissue_type="retina"
gene 1..3440
/gene="PPEF-2"
CDS 368..2629
/gene="PPEF-2"
/note="PPEF-2(L)"
/codon_start=1
/product="protein phosphatase with EF-hands-2 long form"
/protein_id="AAB82796.1"
/translation="MGSGTSTQHHFAFQNAERAFKAAALIQRWYRRYVARLEMRRRCT
WSIFQSIEYAGQQDQVKLHDFFSYLMDHFIPSSHNDRDFLTRIFTEDRFAQDSEMKKC
SDYESIEVPDSYTGPSLSFPLLPDHATALVEAFRLKQQLHARYVLNLLYETKKHLVQL
PNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVE
ILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVHGKEILRTLQDVFC
WLPLATLIDEKVLILHGGVSDITDLELLDKIERSKIVSTMRCKTRQKSEKQMEEKRRA
NQKSSAQGPIPWFLPESRSLPSSPLRLGSYKAQKTSRSSSIPCSGSLDGRELSRQVRS
SVELELERCRQQAGLLVTGEKEEPSRSASEADSEAGELRKPTQEEWRQVVDILWSDPM
AQEGCKANTIRGGGCYFGPDVTQQLLQKYNLQFLIRSHECKPEGYEFCHNRKVLTIFS
ASNYYEVGSNRGAYVKLGPALTPHIVQYQANKVTHTLTMRQRISRVEESALRALREKL
FAHSSDLLSEFKKHDADKVGLITLSDWAAAVESVLHLGLPWRMLRPQLVNSSADNMLE
YKSWLKNLAKEQLSRENIQSSLLETLYRNRSNLETIFRIIDSDHSGFISLDEFRQTWK
LFSSHMNIDITDDCICDLARSIDFNKDGHIDINEFLEAFRLVEKSCPEGDASECPQAT
NAKDSGCSSPGAH"
variation 725..727
/gene="PPEF-2"
/note="Arg/Ser polymorphism"
BASE COUNT 932 a 834 c 814 g 860 t
ORIGIN
1 gaattccgga tttgaagggg gcctgatctg actgacgtca gggggtgcct actccttcga
61 ggcaagaagc ctgaactttc cttcctgtca ctgtgaatac ttggccaggg ctgtgaatgt
121 caccattgct tttcaggaag aagacatggc agactagggc tgcaccttct ttatggctct
181 gtaggtctga agaatcagat cagcctggga tcctcagcca actctgaaga caggatggga
241 tcacgcctgc atgttaaaga gatttctgcc ttgttgtgtc tcatgtaaat aaaaaaccca
301 gcaaagaagc aaacagctca ctgtcctctg gatctgctgc gtcctgcagg agcattgcgc
361 ttaaactatg ggaagcggca cctccaccca acatcatttt gctttccaga atgcagagag
421 agccttcaag gcagcagccc tgatccagag atggtaccgg cgctacgtgg cccgcctgga
481 gatgaggcgg cgttgcacct ggagcatctt ccagtctata gaatatgctg ggcagcaaga
541 ccaagtcaag ctccatgact tcttcagcta tctcatggat cacttcatcc ccagcagcca
601 caacgacagg gacttcctga cccgcatatt cactgaggac agattcgccc aggactccga
661 gatgaagaaa tgcagtgact atgaatccat agaggtaccc gacagttaca cggggccaag
721 cctctccttc ccactcctgc ctgaccatgc aactgccctg gtagaagcat tcagactgaa
781 acaacagctc catgctcgct acgtcttgaa ccttttgtat gaaaccaaga aacatctggt
841 acagctgcca aacatcaacc gggtctcaac ctgttacagc gaggagatca cagtgtgtgg
901 agacttacat ggccaattgg atgacttaat ctttatattt tataagaatg gcctcccatc
961 gccagaacgg tcatatgtgt tcaacggtga ctttgtggat cgaggcaagg attcagtaga
1021 gatcctgatg attctttttg ccttcatgct ggtttacccc aaagagttcc atcttaacag
1081 aggaaaccat gaggaccata tggtgaactt acgatatggc ttcaccaagg aagtgatgaa
1141 taaatacaag gtacacggga aggaaatact aagaaccctg caagatgttt tctgttggct
1201 tccactggcc actctgatag atgagaaagt tctaattctt catggtgggg tgtcagacat
1261 aactgatctg gagcttttgg acaaaataga gaggagcaag atagtttcca ccatgaggtg
1321 caaaacgaga cagaagagtg agaagcagat ggaggagaag agaagagcca accagaagag
1381 ctctgcacag ggacccatcc catggtttct ccccgaaagc cgctctcttc cctcttcgcc
1441 ccttcggctt ggctcctaca aggcccagaa aaccagcagg tcctccagca tcccctgcag
1501 cggttccctg gacgggcggg agctctcccg gcaggtgcgg agctccgtgg aactggagct
1561 agagcggtgc cggcagcaag caggcctcct ggtgaccgga gagaaagagg agccctcccg
1621 ctcagcctca gaagcagact ctgaagccgg agagctgcgg aagcccactc aggaggagtg
1681 gaggcaggtt gtagatatcc tgtggagtga tcccatggct caagagggct gcaaggccaa
1741 cactattcga ggaggaggct gttattttgg gcctgatgtg acacaacagt tgctacaaaa
1801 atacaacctg caattcctga tccgttcaca tgaatgcaaa cctgaaggct atgaattctg
1861 tcacaaccgc aaggtattaa caatcttttc tgcctccaac tactatgaag ttggcagcaa
1921 cagaggggcc tatgtcaaac tggggccagc cctgacccca catatcgtgc agtatcaagc
1981 taacaaggtg acccacacac tcaccatgag gcaaaggatt agcagagtgg aggagtcggc
2041 tctgagagct ctgagggaga agctgtttgc tcattcttca gatcttctca gtgaatttaa
2101 gaagcatgat gcagataaag tcggtttaat caccttgagt gactgggcag cagcggtgga
2161 gtctgtgttg cacctaggac tgccatggcg gatgctgagg ccacagctgg tgaacagctc
2221 agcagacaac atgctggagt acaagtcttg gctgaagaac ttggccaagg aacaactgag
2281 tcgcgagaac atacaatcaa gtttgctgga aacattgtat cgaaaccgat ccaacctaga
2341 gaccattttt aggatcatag acagtgatca ttcagggttc atctcactgg acgagttcag
2401 gcagacctgg aagctgttca gctctcacat gaatatcgac attacagatg actgcatctg
2461 tgaccttgct cggagcattg atttcaacaa agatggccac attgatatca atgagttcct
2521 ggaggccttc cgccttgtgg agaaatcctg cccagagggc gatgcctcag aatgcccaca
2581 agctacaaat gctaaagaca gtggctgcag cagtccaggt gcacactaag aacagcctgg
2641 tcttcatcac ccaaagtgcc tcataggcaa tgctcagctt ctcactagac tatctccctt
2701 attctccatg tgaaacttta tgctgaaaat ttacctatcc atatgcatca gaatcacctg
2761 tgtatttcag tgtggagggg tgggttgggg tgttgtgtat gtatgtgttt taagtatatg
2821 agtgccccaa ccccacctca caatcttcac aaagtagaac ttaggtatag tgttttcaaa
2881 ttctaaagtc cacttcagtt aagaaccact gacaatgtaa ctctctcatt gttttcattt
2941 tatacgtttt tttgagatgg agtttctctc ttgttgccca ggctggagtg cattggcgcg
3001 atctcggctc accgcaaagt ccgcctccca ggcgattctc ctgcctcagc ctcctgagta
3061 gctgggatta caggcatgca ccaccacacc aggataattt tgtattttta gtagacacag
3121 ggtttctcca tgttggtcag gctggtcttg aactcccaac ctcaggtgat ccaccctcct
3181 cagcctccca aagtgctggg attacaggca tgagccaccg cacccagcct attttatact
3241 ttttatttat tgtctttaac aatgtctatt ggtaaagcaa agttattttt aaaaattgta
3301 ttgtaattcc atgacccaag catatggatt ttcttcatta tttacttttt cttacttgtt
3361 actgtagtgt ttatataatt ttatgttcta cttttaaaaa aataaattaa tatctaattg
3421 taaaaaaaaa aaaaaaaaaa
//