LOCUS AF022913 1890 bp mRNA linear HUM 30-SEP-1999
DEFINITION Homo sapiens GPI transamidase mRNA, complete cds.
ACCESSION AF022913
VERSION AF022913.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1890)
AUTHORS Yu,J., Nagarajan,S., Knez,J.J., Udenfriend,S., Chen,R. and
Medof,M.E.
TITLE The affected gene underlying the class K
glycosylphosphatidylinositol (GPI) surface protein defect codes for
the GPI transamidase
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 94 (23), 12580-12585 (1997)
PUBMED 9356492
REFERENCE 2 (bases 1 to 1890)
AUTHORS Yu,J., Nagarajan,S., Knez,J.J., Udenfriend,S., Chen,R. and
Medof,M.E.
TITLE Direct Submission
JOURNAL Submitted (05-SEP-1997) Pathology, Pathology, 2085 AdelbertRoad,
Cleveland, OH 44106, USA
FEATURES Location/Qualifiers
source 1..1890
/db_xref="H-InvDB:HIT000062696"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="ATCC:77441"
/db_xref="taxon:9606"
/chromosome="1"
/cell_line="lymphoblastoid JY1 cells"
/clone_lib="ATTC77441"
CDS 18..1205
/note="GPI8; involved in the class K GPI surface protein
defect; similar to H. sapiens GPI8 protein encoded by
GenBank Accession Number Y07596"
/codon_start=1
/product="GPI transamidase"
/protein_id="AAB81597.1"
/translation="MAVTDSLSRAATVLATVLLLSFGSVAASHIEDQAEQFFRSGHTN
NWAVLVCTSRFWFNYRHVANTLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATV
FSHKNMELNVYGDDVEVDYRSYEVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIY
MTGHGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSP
NIMALASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCP
KSLCVSTPGHRTDLFQRDPKNVLITDFFGSVRKVEITTETIKLQQDSEIMESSYKEDQ
MDEKLMEPLKYAEQLPVAQIIHQKPKLKDWHPPGGFILGLWALIIMVFFKTYGIKHMK
FIF"
BASE COUNT 600 a 320 c 354 g 616 t
ORIGIN
1 atctgaagcc agtaaacatg gccgtcaccg acagcctcag ccgggctgcg actgtcttgg
61 caactgtgtt gctcttgtcc ttcggcagcg tggccgctag tcatatcgag gatcaagcag
121 aacaattctt tagaagtggc catacaaaca actgggctgt tctggtgtgt acatcccgat
181 tctggtttaa ttatcgacat gttgcaaata ccctttctgt ttatagaagt gtcaagaggc
241 taggtattcc tgacagtcac attgtcctaa tgcttgcaga tgatatggcc tgtaatccta
301 gaaatcccaa accagctaca gtgtttagtc acaagaatat ggaactaaat gtgtatggag
361 atgatgtgga agtggattat agaagttatg aggtaactgt ggagaatttt ttacgggtat
421 taactgggag gatcccacct agtactcctc ggtcaaaacg tcttctttct gatgacagaa
481 gcaatattct aatttatatg acagggcatg gtggaaatgg tttcttaaaa tttcaagatt
541 ctgaagaaat taccaacata gaactcgcgg atgcttttga acaaatgtgg cagaaaagac
601 gctacaatga gctactgttt attattgata cttgccaagg agcatccatg tatgaacgat
661 tttattctcc taacataatg gctctagcta gtagtcaagt gggagaagat tcactctcgc
721 atcaacctga tcctgcaatt ggagtccatc ttatggatag atacacattt tatgtcttgg
781 aatttttgga agaaattaac ccagctagcc aaactaatat gaatgacctt tttcaggtat
841 gtcccaaaag tctgtgtgtg tctactcctg gacatcgcac tgatcttttt cagagggatc
901 ctaaaaatgt actgataact gatttctttg gaagtgtacg gaaagtggaa attacaacag
961 agactattaa attgcaacag gattcagaaa tcatggaaag cagctataag gaagaccaga
1021 tggatgagaa actaatggaa cctctgaaat atgctgaaca acttcctgta gctcagataa
1081 tacaccagaa accgaagctg aaagactggc atcctcctgg gggctttatt ctgggattat
1141 gggcacttat tatcatggtt ttcttcaaaa cttatggaat taagcatatg aagttcattt
1201 tttagacttg atgatgaatg aagaatgcat ggaggactgc aaacttggat aataatttat
1261 gtcattatat atttttaaaa atgtgtttct cttgtatgaa ttggaaataa gtataaggaa
1321 actaaatttg aatcaactat taattttata acttaaagaa aaataattgt taatgcaact
1381 gcttaatggc actaaatata ttccagtttt gtattttgtg tattataaaa gcgaatgaga
1441 cagagatcag aatacattga ctgtttttga aaatagtaat ttccccttat ccccttttca
1501 tttggaaaag aaacaattgt gaagacatta aattctcact aacagaagta actttggtta
1561 attatttttt gtatatcctc ccaatctttt gacttatgca catatttttt cccaatatgg
1621 agatcatatg gaatgtacta ttttgtaatg tcttttttca ttttacaatg tattatcaac
1681 cttttccctc tcaaaaatac attgtgaatg actgcatagt attcacttta tgaatattta
1741 attcatttca cagtcttcta ttgttggacc acttacattg taccaaatgt tttcctttgg
1801 tttattcttt aatgtattaa tattttactg ctggtcactc atggaatcct gcagctttaa
1861 ttaaaagcaa agatgaaaaa aaaaaaaaaa
//