LOCUS AF022797 2238 bp mRNA linear HUM 11-DEC-1997
DEFINITION Homo sapiens intermediate conductance calcium-activated potassium
channel (hKCa4) mRNA, complete cds.
ACCESSION AF022797
VERSION AF022797.1
KEYWORDS intermediate conductance; charybdotoxin-sensitive; lymphocytes.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2238)
AUTHORS Logsdon,N.J., Kang,J., Togo,J.A., Christian,E.P. and Aiyar,J.
TITLE A novel gene, hKCa4, encodes the calcium-activated potassium
channel in human T lymphocytes
JOURNAL J. Biol. Chem. 272 (52), 32723-32726 (1997)
PUBMED 9407042
REFERENCE 2 (bases 1 to 2238)
AUTHORS Logsdon,N.J., Kang,J., Togo,J.A., Christian,E.P. and Aiyar,J.
TITLE Direct Submission
JOURNAL Submitted (04-SEP-1997) Target Discovery, Zeneca Pharmaceuticals,
1800 Concord Pike, Wilmington, DE 19897, USA
FEATURES Location/Qualifiers
source 1..2238
/db_xref="H-InvDB:HIT000062688"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="lymph node"
gene 1..2238
/gene="hKCa4"
CDS 397..1680
/gene="hKCa4"
/codon_start=1
/product="intermediate conductance calcium-activated
potassium channel"
/protein_id="AAC51913.1"
/translation="MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHA
EMLWFGGCSWALYLFLVKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTG
RQAAQIVLELVVCGLHPAPVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRL
YLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLT
TAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVC
CTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFYKHTRRKES
HAARRHQRKLLAAINAFRQVRLKHRKLREQVNSMVDISKMHMILYDLQQNLSSSHRAL
EKQIDTLAGKLDALTELLSTALGPRQLPEPSQQSK"
regulatory 2221..2226
/regulatory_class="polyA_signal_sequence"
/gene="hKCa4"
BASE COUNT 421 a 666 c 707 g 444 t
ORIGIN
1 gtccttcggt gtctgggtgt ggtgagtaga ggtgtgtgtc acaaagtaca gaccattgtg
61 tgtgacaaag cccatcgtgt gtctgtgtgt gtctttatcc acgtggatgg acgtctcttt
121 cttgctctgc cccaagacac accctagccc ctccttattc tcaaaagggg gagctgggga
181 gcctccccct accctggggc ctcccctgcc cctccccgcc ctgcctggcc gtcaccactc
241 cccagagggc acagggctct gctgtgcctc agagcaaaag tcccagagcc agcagagcag
301 gctgacgacc tgcaagccac agtggctgcc ctgtgcgtgc tgcgaggtgg gggaccctgg
361 gcaggaagct ggctgagccc caagaccccg ggggccatgg gcggggatct ggtgcttggc
421 ctgggggcct tgagacgccg aaagcgcttg ctggagcagg agaagtctct ggccggctgg
481 gcactggtgc tggcaggaac tggcattgga ctcatggtgc tgcatgcaga gatgctgtgg
541 ttcggggggt gctcgtgggc gctctacctg ttcctggtta aatgcacgat cagcatttcc
601 accttcttac tcctctgcct catcgtggcc tttcatgcca aagaggtcca gctgttcatg
661 accgacaacg ggctgcggga ctggcgcgtg gcgctgaccg ggcggcaggc ggcgcagatc
721 gtgctggagc tggtggtgtg tgggctgcac ccggcgcccg tgcggggccc gccgtgcgtg
781 caggatttag gggcgccgct gacctccccg cagccctggc cgggattcct gggccaaggg
841 gaagcgctgc tgtccctggc catgctgctg cgtctctacc tggtgccccg cgccgtgctc
901 ctgcgcagcg gcgtcctgct caacgcttcc taccgcagca tcggcgctct caatcaagtc
961 cgcttccgcc actggttcgt ggccaagctt tacatgaaca cgcaccctgg ccgcctgctg
1021 ctcggcctca cgcttggcct ctggctgacc accgcctggg tgctgtccgt ggccgagagg
1081 caggctgtta atgccactgg gcacctttca gacacacttt ggctgatccc catcacattc
1141 ctgaccatcg gctatggtga cgtggtgccg ggcaccatgt ggggcaagat cgtctgcctg
1201 tgcactggag tcatgggtgt ctgctgcaca gccctgctgg tggccgtggt ggcccggaag
1261 ctggagttta acaaggcaga gaagcacgtg cacaacttca tgatggatat ccagtatacc
1321 aaagagatga aggagtccgc tgcccgagtg ctacaagaag cctggatgtt ctacaaacat
1381 actcgcagga aggagtctca tgctgcccgc aggcatcagc gcaagctgct ggccgccatc
1441 aacgcgttcc gccaggtgcg gctgaaacac cggaagctcc gggaacaagt gaactccatg
1501 gtggacatct ccaagatgca catgatcctg tatgacctgc agcagaatct gagcagctca
1561 caccgggccc tggagaaaca gattgacacg ctggcgggga agctggatgc cctgactgag
1621 ctgcttagca ctgccctggg gccgaggcag cttccagaac ccagccagca gtccaagtag
1681 ctggacccac gaggaggaac caggctactt tccccagtac tgaggtggtg gacatcgtct
1741 ctgccactcc tgacccagcc ctgaacaaag cacctcaagt gcaaggacca aagggggccc
1801 tggcttggag tgggttggct tgctgatggc tgctggaggg gacgctggct aaagtgggta
1861 ggccttggcc cacctgaggc cccaggtggg aacatggtca cccccactct gcataccctc
1921 atcaaaaaca ctctcactat gctgctatgg acgacctcca gctctcagtt acaagtgcag
1981 gcgactggag gcaggactcc tgggtccctg ggaaagaggg tactaggggc ccggatccag
2041 gattctggga ggcttcagtt accgctggcc gagctgaaga actgggtatg aggctggggc
2101 ggggctggag gtggcgcccc ctggtgggac aacaaagagg acaccatttt tccagagctg
2161 cagagagcac ctggtgggga ggaagaagtg taactcacca gcctctgctc ttatctttgt
2221 aataaatgtt aaagccag
//