LOCUS AF022789 4348 bp mRNA linear HUM 25-JUL-2016
DEFINITION Homo sapiens ubiquitin hydrolyzing enzyme I (UBH1) mRNA, partial
cds.
ACCESSION AF022789
VERSION AF022789.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4348)
AUTHORS Hansen-Hagge,T.E., Janssen,J.W., Hameister,H., Papa,F.R.,
Zechner,U., Seriu,T., Jauch,A., Becke,D., Hochstrasser,M. and
Bartram,C.R.
TITLE An evolutionarily conserved gene on human chromosome 5q33-q34,
UBH1, encodes a novel deubiquitinating enzyme
JOURNAL Genomics 49 (3), 411-418 (1998)
PUBMED 9615226
REFERENCE 2 (bases 1 to 4348)
AUTHORS Hansen-Hagge,T.E., Janssen,J.W.G., Hameister,H., Jauch,A., Papa,F.,
Zechner,U., Seriu,T., Hochstrasser,M. and Bartram,C.R.
TITLE Direct Submission
JOURNAL Submitted (02-SEP-1997) Dept. of Dermatology,
Charite/Humboldt-University/Berlin, Schumannstr. 20 /21, Berlin
10117, Germany
FEATURES Location/Qualifiers
source 1..4348
/db_xref="H-InvDB:HIT000062685"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q33-q34"
gene <1..4348
/gene="UBH1"
CDS <153..1220
/gene="UBH1"
/function="hydrolyzes the amide bond between the
C-terminus of ubiquitin and the amino groups of conjugated
proteins"
/note="member of the deubiquitinating enzyme (DUB) family;
an upstream ATG could be used for initiation of
translation"
/codon_start=1
/product="ubiquitin hydrolyzing enzyme I"
/protein_id="AAC23551.1"
/translation="MGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYF
CRPFREKVLAYKSQPRKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELF
DNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVHEI
FQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYC
EECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSG
DATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYG
LTSDISKNSESGYILFYQSRD"
BASE COUNT 1344 a 728 c 881 g 1395 t
ORIGIN
1 gggctcgggg tccgcccgcg ggctgccggt gcgagcgggc ggcccggctc ccctcctccc
61 ccgcccgccg ccgccgctgt gattgggtgg aagatggcgc tggccggatg gaaatcctaa
121 tgacagtctc caaattcgcc tccatctgta ccatgggcgc caatgcttcg gcattagaga
181 aagagattgg tccagaacag tttccggtca atgagcacta ttttggatta gtcaattttg
241 ggaatacctg ctactgcaat tcagttcttc aagcacttta tttttgtcgt ccatttcggg
301 aaaaagttct tgcgtataag agtcaaccta ggaaaaagga gagccttctt acatgcttag
361 cagatctctt ccatagcata gccactcaga agaaaaaggt tggagtaata ccccctaaga
421 agttcatcac aagattacgg aaagaaaatg agctttttga caactacatg caacaagatg
481 cccatgaatt cttaaattac ctactaaata caattgctga tattttacaa gaagagagaa
541 agcaggaaaa acaaaatggt cgtttaccta atggtaatat tgataatgaa aataataaca
601 gcacaccaga cccaacgtgg gttcatgaga tttttcaggg aacattaact aatgaaacca
661 gatgtcttac ttgtgaaact ataagcagca aagatgaaga ttttttagac ctttctgttg
721 acgtggaaca aaatacatca attactcact gcttaagggg tttcagcaac acagaaactc
781 tgtgcagtga atacaagtat tactgtgaag agtgtcgcag caaacaggaa gcacacaaac
841 ggatgaaagt taaaaaactg cccatgattc tagctctaca cctgaagaga tttaaatata
901 tggatcaact tcatcgatat acaaaactct cttaccgggt agtttttcct ttagaacttc
961 gtctgtttaa cacttcaggt gatgccacca atccagacag aatgtacgac cttgttgctg
1021 ttgtggttca ctgtggaagt ggtcccaatc gaggccatta tattgcaata gttaagagtc
1081 atgatttttg gttgttgttt gatgacgaca ttgtagaaaa aatagatgca caagctattg
1141 aagaattcta cgggttgaca tcagatatct caaagaactc tgagtctggt tacatccttt
1201 tctatcagtc tcgggactga gagggaaccg tgatgaagag acactttctg cctcatttct
1261 tctctggtta ttttggaaag gatcaagcac tgatttttca agaaaagaga aatgcaggaa
1321 gctcaggggg cagtagcaca ctttgcacac gataaagcaa agacgatgga ttgacaagcc
1381 cttccgatca tggtagttga tttatttgct caggtatcat gctgtctgta cagttccata
1441 caacaaggag gtgaaatcag agataccagc tcctctttta aaacagcctt ccagtcattg
1501 gcacgcattt tctctttatt aattgcacca ataatgcttt gaattccttg ggggtgcagt
1561 agaaagaatc ggaatctgtg ccgtattgat aaggagatga tgttgaacac actgcataaa
1621 tttgcctggt tcagtatgta tagaaggcat attcagtggt cttttcaaga gtaaaccaga
1681 aatacttttg ggcccaacac ttgcagttgc cttcctgatg taaaaactaa catgctagat
1741 aatccagtgt cgggaagaca aagatgtttt gcttctctga agaagcttat aataatatac
1801 agtatatgta tatgtaggga gcaattggtc aaaagtggct ttttgtttcc ccaagggaaa
1861 gactggcttt gtaattataa ttttttcctt atttatttta cttaaaactg gtagagtcta
1921 agtattatat gaagtgccca tgattctgtc agtaaatttg aacatatttt tattagttaa
1981 tgtcagttta agttgtcctt ttgtttgttt ctatttttaa ggtgaatttt aatttctatc
2041 tgaaatcagt taagatacct tgagaaaaac tgcagtgaga ggagataaat atcctttttc
2101 aggaggaact gatatctctg gctaaatatt tgtcctttta ttatggtttc taaatcagtt
2161 attttcttca gctttaattt cataaaatta aaaaactatt ttaaaaattc ctgtagttgt
2221 tggaataatt aaaaattctg gtgcagtggt ggtataccaa tctttagaat tcttaagtat
2281 tctaatgttt caagttgaga tcatgcttgg gaaaatcatg tcatagcatt tatgttattt
2341 tcagatgcca ttttttaccc tggaaagaag tcataatgtt catcataacc ctagcagcct
2401 ggatagtgag ctaaacaaac ccttcaaaga ttaaatttta atcaagtaga ccgggaatac
2461 aaaagacaag tccttccttc ccttcccccc acctttacaa atcttactgg aagggtgttc
2521 agaaattaaa atctgtgttt gctaagactt cattctgttg ggggttttaa gaagtaatat
2581 atgtaacata aaatatatgt aaacgattgc agtttttttg gacgtttttc catgcatcag
2641 taagttgtct gacagtagcc aaatgtaact tgcagaaaat tattgaaaat tatattcaga
2701 ataatagcaa tcaggccttg gatgttcttt attaaactct tttcaggcag taaatttaaa
2761 aaaaattgtc attttctaaa gtccttttgc taaaactgtt gactatggaa aacaacaaaa
2821 aggaattttt tagtctgctg ctattattaa catttattat ctgtatcttt tggctcagga
2881 aatgacttca cctatttttt ccataagcag acctttaaca gagtcactta attgggctgc
2941 ttaaacggat gttctgggag aaaattataa tatttagtat ttgtacaaaa tatcaaaaag
3001 tattttgaca agtttctttt taagatagtt cctaaagcct taccctggct agaggtgttt
3061 tgtacaaatt atatataagc cagcctgatc taccaacatg ccacagagaa tcacaatcaa
3121 cagtgtgggg aaagtcaggg cagtggaagt ggatgcactc tttttatttt gaaggcttaa
3181 accaaattgt cttggaatta aagctgtatt tctgcagctt tcggtacaga gaaaaagagg
3241 aaagtgaagc tgtgtcagtt ttaacattag ctatatcaac atgtttaaga aagatagatg
3301 aagtcatttg cataaaggta cagcattgaa atactatgtt gtgtttgttt ttacattttt
3361 gcattaaaaa aaaacatgcc gtaaaagcca agttaaattt catattaaag caagttctag
3421 tgtatgtgtt gagttcctgg taatcacata cttgttcaca tctacaccgt acttcatagt
3481 atgatttgtc aggggaggga ttgtggggtg acagttttac atttactttt tcttcttaat
3541 gcagctggat ctaagtaaaa tgttttgaag tttatcagaa actaaatgta cttttaaaac
3601 gtatagggtc agggttgggg gaaaaataca ggtatagtaa gtaagaaaag tgacccatga
3661 agaaagcatc gtgaggttgt atgttggttg actgtgatta aaatgcgggg ctggtgtaag
3721 ttgtaagtgg tggctgattg ccgtgtaact atgtacatga ttgttgggat ggctgtccca
3781 tattttgtat attggaataa aaatttctat aaattattgt aactaaaagt aaatattcta
3841 aattaagtcc cacttcttaa gtcacatggc ttctgtcttg gaaattttac ctttaaaaga
3901 ttatttaaga caggaaccag gaggcttggg aacagggaaa gagggaaatg ttgtattatg
3961 tgggtcttgg ggcctctaac catcagtata gggttttttc tttccttgat ggcagtagaa
4021 agacctcatt ttcataacat aactactctt gatactttct ttaaaaacac tttttattaa
4081 agattctatc atgaggtatt tggctgggag ctgggaggct aaagcgctca tgtcctggct
4141 cttcagtgaa tttaactgtg tgaccttggg caagtcactt aacctctctg tgcttcagtc
4201 tccctgtctt gtaaaatggg agtaatacct acctcacagg gttgttgtgg ggattaatta
4261 gagataatgt ctgtaaagca tttaaggttc ttgaagaagg cactatataa atacaaaata
4321 atatctatta aagttggttt atttgtga
//