LOCUS AF022655 7814 bp mRNA linear HUM 25-MAR-1998
DEFINITION Homo sapiens cep250 centrosome associated protein mRNA, complete
cds.
ACCESSION AF022655
VERSION AF022655.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7814)
AUTHORS Mack,G.J., Rees,J., Sandblom,O., Balczon,R., Fritzler,M.J. and
Rattner,J.B.
TITLE Autoantibodies to a group of centrosomal proteins in human
autoimmune sera reactive with the centrosome
JOURNAL Arthritis Rheum. 41 (3), 551-558 (1998)
PUBMED 9506584
REFERENCE 2 (bases 1 to 7814)
AUTHORS Mack,G.J., Rees,J., Sandblom,O., Balczon,R., Fritzler,M.J. and
Rattner,J.B.
TITLE Direct Submission
JOURNAL Submitted (03-SEP-1997) Med. Biochemistry, University of Calgary,
3330 Hospital Dr. NW., Calgary, AB T2N-4N1, Canada
REFERENCE 3 (bases 1 to 7814)
AUTHORS Mack,G.J., Rees,J., Sandblom,O., Balczon,R., Fritzler,M.J. and
Rattner,J.B.
TITLE Direct Submission
JOURNAL Submitted (04-FEB-1998) Med. Biochemistry, University of Calgary,
3330 Hospital Dr. NW., Calgary, AB T2N-4N1, Canada
REMARK Sequence update by submitter
COMMENT On Feb 5, 1998 this sequence version replaced gi:2564643.
FEATURES Location/Qualifiers
source 1..7814
/db_xref="H-InvDB:HIT000062680"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
CDS 222..7550
/codon_start=1
/product="cep250 centrosome associated protein"
/protein_id="AAC06349.1"
/translation="METRSPGLNNMKPQSLQLVLEEQVLALQQQMAENQAASWRKLKN
SQEAQQRQATLVRKLQAKVLQYRSWCQELEKRLEATGGPIPQRWENVEEPNLDELLVR
LEEEQQRCESLAEVNTQIRLHMEKADVVNKALRADVEKLTVDWSRARDELMRKESQWQ
MEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDRDLMELKAEHVRLSGSLLT
CCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDL
EKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNA
QEEKLSLQQVIKDITQVMVEEGDNIAQGSGLENSLELESSIFSQFDYQDADKALTLVR
SVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQ
TVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKE
EQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESIHLEGELLRQEQTEV
TAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEE
ENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADL
RDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAA
LEVRLQAVERDRQDLAAQLQGLSSAKELLESSLFEAQQQNSVIDEPQGQLEVQIQTVT
QAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVN
QLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAES
ALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQ
LQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVE
QEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQD
MQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQE
AKAAQLHLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELS
GGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALLKLHQDLWKTQQTRDVL
RDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHE
TMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILE
EDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEE
VETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPM
AVQEREQKLTVQREQIREPEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL
VTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQ
IHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQ
VLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEH
MKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQ
QQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADA
LQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQE
KALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEA
ARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLE
EALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMI
QEKQNLGLEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTS
PMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSL
QEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQL
GEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERE
RRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQKNSNAKCVAELQKEVVLLQAQLT
LERKQKQDYITRSAQTSRELAGLHHSLSHSLLAVAQAPEATVLEAETRRLDESLTQSL
TSPGPVLLHPSPSTTQAASR"
BASE COUNT 2188 a 1867 c 2581 g 1178 t
ORIGIN
1 ggaattccgg gaaatcctgg gataagagaa tagtttcctg gaagatctgt gcctccaacc
61 agcagagagg gattgagctt cattgaactc aacagagcca acatttcata gcaccatgtt
121 caagaggagg ttgaagtggc atggcaatgg ttagagaccc tgctgggcgt gaacaccctc
181 tggctaccta gggacctgtg ggcctaccac ctggtgccct catggagaca agaagccctg
241 ggttgaacaa catgaagccc cagtcactgc agctggtact ggaagagcag gtgctggcac
301 tacagcagca gatggcagag aatcaggcag cctcctggcg gaagctgaag aactcccagg
361 aggcccagca gagacaagca acccttgtga ggaagctgca ggccaaggtg ctgcagtacc
421 gaagctggtg ccaagagctg gagaagcggc tagaagccac tggaggacca atcccccaga
481 ggtgggaaaa tgtggaggag ccaaacctgg atgagctgct ggtccgattg gaggaggagc
541 aacagaggtg tgagagtcta gcagaggtga acacccagat tcgactgcac atggaaaaag
601 ctgacgtggt gaataaagcc cttagggcag atgtggaaaa actgacagtg gactggagcc
661 gggcccggga tgagctaatg aggaaggaga gccagtggca gatggagcag gagttcttca
721 agggctacct gaaaggggag cacggtcgcc ttctcagtct atggcgggag gttgtgacat
781 tccgacgcca cttcctggaa atgaagtcag ctactgacag agatctgatg gagctaaaag
841 ctgagcatgt gaggctttca gggtctctgt tgacctgttg tctgcgcttg actgtgggag
901 cacagtctcg ggaacccaac ggatctggaa gaatggatgg gcgggagccg gcccagctgc
961 tgctgctact agccaagacc caggagctgg agaaggaagc ccatgaaagg agccaggagt
1021 taatacagct gaagagtcaa ggggatctgg agaaggctga acttcaggac cgggtgaccg
1081 agctctctgc tctgttgacc cagtctcaga agcaaaatga agattatgaa aagatgataa
1141 aggctctgag agagacagtg gagatcctgg agacaaatca cacagaatta atggaacatg
1201 aagcatctct tagtaggaat gcgcaagagg agaagttgtc tttacagcag gtgatcaagg
1261 atataaccca ggtcatggtg gaagaagggg acaatatagc ccaaggctct ggtcttgaga
1321 actctttgga attggagtct agtatcttct cccagtttga ttaccaagat gcagacaagg
1381 ctcttactct ggtgcgttca gtgctgactc ggagacgcca ggctgtgcag gacctaaggc
1441 agcagcttgc aggctgtcaa gaggctgtga acttgttgca acagcagcat gatcagtggg
1501 aggaagaggg caaagccttg agacagcggc tgcagaagct cactggggag cgggacactc
1561 tggcagggca gactgtggac ctccagggag aggtggactc tctcagcaag gagcgagagc
1621 tgctgcagaa ggccagggaa gagctgcggc agcagctgga ggtgctagag caggaggcat
1681 ggcgcctgcg aagggtaaat gtggagcttc agctgcaggg ggactctgcc cagggccaga
1741 aggaggaaca gcaggaggag ctgcacctgg ctgtccggga gagggagcgt cttcaggaga
1801 tgctgatggg cctggaagcc aaacagtcag aatcactcag tgaactgatc actcttcggg
1861 aagccctgga gtcaattcac ctggaagggg agttactgag gcaagagcaa acggaagtga
1921 ccgcagcgct ggctagggca gagcagtcaa ttgcagagct gtcgagttct gaaaacaccc
1981 tgaagacaga agtagctgat cttcgggctg cagctgtcaa gctcagtgcc ttaaatgagg
2041 ctttggcgtt agataaagtt gggctgaacc agcagcttct ccagttagag gaggagaacc
2101 agtctgtgtg cagcagaatg gaggccgcag agcaggcgag aaatgctttg caggtcgacc
2161 tggcggaggc agagaagagg agggaagccc tgtgggaaaa gaacactcac ctggaggctc
2221 agctgcagaa agctgaggag gctggggctg agctgcaggc agatctcagg gacatccaag
2281 aagagaagga agaaattcaa aagaaactaa gtgagtcacg tcaccagcag gaggcagcca
2341 cgactcagct ggagcagcta catcaggagg caaagcgaca ggaagaagtg cttgccaggg
2401 cagtccagga gaaggaggcc ctagtacgag agaaagcggc tctagaggtg cggctgcagg
2461 ccgtggagcg tgaccggcag gacctcgctg cacaactaca ggggctcagc tcagccaagg
2521 agctactgga gagcagtctg tttgaagccc aacaacaaaa ttctgtgata gacgagccgc
2581 aggggcagct ggaggtccag attcaaactg tcactcaagc caaggaagta atccaagggg
2641 aagtgaggtg cctgaagctg gaactggaca ctgaacggag tcaggcagag caggagcggg
2701 atgctgcagc cagacagctg gcccaggctg agcaagaagg gaagactgcc ttggagcagc
2761 agaaggcagc ccatgagaaa gaggtgaacc agctccggga gaaatgggag aaggagcgct
2821 cctggcacca gcaggagctg gcaaaggctc tggagagctt agaaagggaa aaaatggagc
2881 tggaaatgag gctaaaggag cagcagacag aaatggaggc catccaggcc cagagggaag
2941 aagaacggac ccaggcagag agtgccctat gccagatgca gctggaaaca gagaaggaga
3001 gagtatccct cctggagaca ctgctgcaga cgcagaagga gctagcagat gccagccaac
3061 aactggaacg actgaggcag gacatgaaag tccagaaatt aaaggagcag gagaccactg
3121 ggatactaca gacccagctc caggaggctc aacgggagct gaaggaggca gcccggcagc
3181 acagagatga ccttgctgcc ctccaagaag agagcagctc cctgctgcag gataagatgg
3241 acctgcagaa gcaggtggag gacttgaagt ctcagctggt ggcccaggat gactcccaga
3301 ggctggtgga gcaggaggtt caggagaagc tgagagagac ccaggagtat aaccgaattc
3361 agaaggagct ggagagagag aaagccagcc tgactctgtc actgatggaa aaggaacaga
3421 gactccttgt tttacaagaa gctgactcta ttcgacaaca agagctgagt gccctgcgcc
3481 aggacatgca ggaggcccag ggagaacaga aagagctcag tgctcagatg gaattactaa
3541 ggcaagaggt gaaggaaaag gaggctgact ttctggccca ggaagcacag ctgctggagg
3601 agctggaggc gtctcatatc acggagcagc agctgcgagc ctccttgtgg gcccaggaag
3661 ccaaggcagc ccaactacac ctgcgactgc gcagcacaga gagccagcta gaagcgctgg
3721 ccgcagagca gcagcccggg aaccaggccc aggcccaggc ccagctggcc agcctctact
3781 ctgccctgca gcaggccctg gggtctgttt gtgagagcag gcctgagctg agtggtgggg
3841 gagactctgc tccttccgtc tggggccttg agccagacca gaatggagct aggagcctct
3901 ttaagagagg gcccctgctg actgctctct ccgctgaggc agtagcatct gccctcctca
3961 agcttcatca agacctgtgg aagactcaac agacccggga tgttctgagg gatcaggtcc
4021 agaaactgga agagcgtcta actgatactg aggctgagaa gagccaggtc cacacagagt
4081 tgcaggatct gcagagacag ctctcccaga atcaggaaga gaaatccaag tgggaaggaa
4141 agcagaactc cctagaatct gagctgatgg aactacatga aactatggca tccttacaga
4201 gtcgcctgcg gagagcagag ctacagcgaa tggaagccca gggtgagcga gagttacttc
4261 aggcagccaa ggagaacctg acagcccagg tggaacacct gcaagcagct gtcgtagaag
4321 ccagggctca ggcaagtgct gctggcatcc tggaagaaga cctgagaacg gctcgctcag
4381 cactgaagct gaaaaatgag gaagtagaga gtgagcgtga gagagcccag gctctgcaag
4441 agcagggcga actgaaggtg gcccaaggga aggctctgca agagaatttg gccctcctga
4501 cccagaccct agctgaaaga gaagaggagg tggagactct gcggggacaa atccaggaac
4561 tggagaagca acgggaaatg cagaaggctg ctttggaatt gctgtctctg gacctgaaga
4621 agaggaacca agaggtagat ctgcagcaag aacagattca ggagctagag aagtgtaggt
4681 ctgttttaga gcatctgccc atggccgtcc aggagcgaga gcagaagctg actgtgcaga
4741 gggagcagat cagagagccc gagaaggatc gggagactca gaggaacgtc ttggagcatc
4801 agcttctaga acttgagaag aaagaccaaa tgattgagtc ccagagagga caggttcagg
4861 acctgaaaaa gcagttggtt actctggaat gcctggccct ggaactggag gaaaaccatc
4921 acaagatgga gtgccagcaa aaactgatca aggagctgga gggccagagg gaaacccaga
4981 gagtggcttt gacccacctt acgctggacc tagaagaaag gagccaggag ctgcaggcac
5041 aaagcagcca gatccatgac ctggagagcc acagcaccgt tctggcaaga gagctgcagg
5101 agagggacca ggaggtgaag tctcagcgag aacagatcga ggagctgcag aggcagaaag
5161 agcatctgac tcaggatctc gagaggagag accaggagct gatgctgcag aaggagagga
5221 ttcaggttct cgaggatcag aggacccggc agaccaagat cctggaggag gacctggaac
5281 agatcaagct gtccttgaga gagcgaggcc gggagctgac cactcagagg cagctgatgc
5341 aggaacgggc agaggaaggg aagggcccaa gtaaagcaca gcgcgggagc ctagagcaca
5401 tgaagctgat cctgcgtgat aaggagaagg aggtggaatg tcagcaggag catatccatg
5461 aactccagga gctcaaagac cagctggagc agcagctcca gggcctgcac aggaaggtag
5521 gtgagaccag cctcctcctg tcccagcgag agcaggaaat agtggtcctg cagcagcaac
5581 tgcaggaagc cagggaacaa ggggagctga aggagcagtc acttcagagt caactggatg
5641 aggcccagag agccctagcc cagagggacc aggaactgga ggctctgcag caagaacagc
5701 agcaggccca gggacaggag gagagggtga aggaaaaggc agacgccctc cagggagctc
5761 tggagcaagc ccatatgaca ctgaaggagc gtcatggaga gcttcaggac cacaaggaac
5821 aggcacgaag gctggaggaa gagctggcag tggagggacg gcgggtccaa gccctggagg
5881 aggtgctggg agacctaagg gctgagtctc gggaacagga gaaagctctg ttggccctcc
5941 agcagcagtg tgctgagcag gcacaggagc atgaggtgga gaccagggcc ctgcaggaca
6001 gctggctgca ggcccaggca gtgctcaagg aacgggacca ggagctggaa gctctgcggg
6061 cagaaagtca gtcctcccgg catcaggagg aggctgcccg ggcccgggct gaggctctgc
6121 aggaggccct tggcaaggct catgctgccc tgcaggggaa agagcagcat ctcctcgagc
6181 aggcagaatt gagccgcagt ctggaggcca gcactgcaac cctgcaagcc tccctggatg
6241 cctgccaggc acacagtcgg cagctggagg aggctctgag gatacaagaa ggtgagatcc
6301 aggaccagga tctccgatac caggaggatg tgcagcagct gcagcaggca cttgcccaga
6361 gggatgaaga gctgagacat cagcaggaac gggagcagct gctggagaag tctctggccc
6421 agagggtcca agagaatatg atccaagaga agcagaatct ggggctagag agagaagagg
6481 aggagataag gggccttcat cagagtgtaa gggagctaca gctgactcta gcccaaaagg
6541 aacaggagat tctggagctg agggagaccc agcaaaggaa caacctggaa gccttacccc
6601 acagccacaa aacctcccca atggaggaac aatctctaaa acttgattct ttagagccca
6661 ggctgcagcg ggagctggag cggctacagg cagccctgag acagacagaa gccagggaga
6721 ttgagtggag ggagaaggcc caggacttgg cactctccct agcgcagacc aaggccagtg
6781 tcagcagtct gcaggaggtt gccatgttcc tacaagcctc tgtcctggag cgggactcag
6841 aacagcaaag gctgcaggat gaactggagc tcaccagacg ggctctggag aaggagcggc
6901 tacacagccc aggtgcaacc agcacagcag aactggggtc cagaggggag cagggtgtgc
6961 agctgggaga ggtctcagga gtggaggctg agcctagtcc tgatggaatg gagaagcagt
7021 catggagaca aaggcttgaa cacctgcagc aagcagtggc ccggctggag attgacagga
7081 gcaggctgca gcgccacaat gtccagctgc ggagtacctt ggagcaggtg gagcgagaac
7141 ggaggaagct gaagagggag gccatgcgtg cggcccaggc agggtcccta gagatcagca
7201 aggccacggc ttcttcaccc acacagcagg atgggagagg acagaagaac tcaaatgcca
7261 agtgtgtggc tgaactgcag aaagaggtgg tcctgctgca agctcagctg actttggagc
7321 ggaagcagaa gcaggactac atcacccgct cagcacagac cagccgtgag ctagcaggcc
7381 tgcaccacag cctctcacac tcacttcttg ccgtggccca ggcccctgag gccactgtcc
7441 tggaggcaga gacccgcagg ctggatgagt ccctgactca aagtctgaca tccccagggc
7501 cagtcctgct acaccccagc cccagcacta cccaagccgc ctccaggtag cagccacagc
7561 caggagcaca cagacagaag actgtgtcat gggtcatggc ccctccgcac acctacaggt
7621 ttgccaaagg aaaagcctgg ctctgttagg cacccaggag ccccaggtcg gcgggtgttc
7681 ccaggaagag gaagtaaatc tgcaaccctg gggaggaccc caactcacct gggaatgagg
7741 caaattgcat ttgcttgctc cctatggaat cacccagagg ggtgccttgc cctggctgag
7801 ggacccggaa ttcc
//