LOCUS AF021351 4176 bp mRNA linear HUM 19-NOV-1997
DEFINITION Homo sapiens RNA polymerase III largest subunit (hRPC155) mRNA,
complete cds.
ACCESSION AF021351
VERSION AF021351.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4176)
AUTHORS Sepehri,S. and Hernandez,N.
TITLE The largest subunit of human RNA polymerase III is closely related
to the largest subunit of yeast and trypanosome RNA polymerase III
JOURNAL Genome Res. 7 (10), 1006-1019 (1997)
PUBMED 9331371
REFERENCE 2 (bases 1 to 4176)
AUTHORS Sepehri,S. and Hernandez,N.
TITLE Direct Submission
JOURNAL Submitted (26-AUG-1997) James Building, Cold Spring Harbor
Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
FEATURES Location/Qualifiers
source 1..4176
/db_xref="H-InvDB:HIT000062572"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/note="cDNA clone from NTera2D1 cDNA library with
supplemental sequence from total Hela cDNA"
gene 1..4176
/gene="hRPC155"
CDS 1..4176
/gene="hRPC155"
/note="DNA-dependent RNA polymerase; similar to beta-prime
(b') subunit of E.coli RNA polymerase"
/codon_start=1
/product="RNA polymerase III largest subunit"
/protein_id="AAB86536.1"
/translation="MVKEQFRETDVAKKTSHICFGMKSPEEMRQQAHIQVVSKNLYSQ
DNQHAPLLYGVLDHRMGTSEKDRPCETCGKNLADCLGHYGYIDLELPCFHVGYFRAVI
GILQMICKTCCHIMLSQEEKKQFLDYLKRPGLTYLQKRGLKKKISDKCRKKNICHHCG
AFNGTVKKCGLLKIIHEKYKTNKKVVDPIVSNFLQSFETAIEHNKEVEPLLGRAQENL
NPLVVLNLFKRIPAEDVPLLLMNPEAGKPSDLILTRLLVPPLCFRPSVVSDLKSGTNE
DDLTMKLTEIIFLNDVIKKHRISGAKTQMIMEDWDFLQLQCALYINSELSGIPLNMAP
KKWTRGFVQRLKGKQGRFRGNLSGKRVDFSGRTVISPDPNLRIDEVAVPVHVAKILTF
PEKVNKANINFLRKLVQNGPEVHPGANFIQQRHTQMKRFLKYGNREKMAQELKYGDIV
ERHLIDGDVVLFNRQPSLHKLSIMAHLARVKPHRTFRFNECVCTPYNADFDGDEMNLH
LPQTEEAKAEALVLMGTKANLVTPRNGEPLIAAIQDFLTGAYLLTLKDTFFDRAKACQ
IIASILVGKDEKIKVRLPPPTILKPVTLWTGKQIFSVILRPSDDNPVRANLRTKGKQY
CGKGEDLCANDSYVTIQNSELMSGSMDKGTLGSGSKNNIFYILLRDWGQNEAADAMSR
LARLAPVYLSNRGFSIGIGDVTPGQGLLKAKYELLNAGYKKCDEYIEALNTGKLQQQP
GCTAEETLEALILKELSVIRDHAGSACLRELDKSNSPLTMALCGSKGSFINISQMIAC
VGQQAISGSRVPDGFENRSLPHFEKHSKLPAAKGFVANSFYSGLTPTEFFFHTMAGRE
GLVDTAVKTAETGYMQRRLVKSLEDLCSQYDLTVRSSTGDIIQFIYGGDGLDPAAMEG
KDEPLEFKRVLDNIKAVFPCPSEPALSKNELILTTESIMKKSEFLCCQDSFLQEIKKF
IKGVSEKIKKTRDKYGINDNGTTEPRVLYQLDRITPTQVEKFLETCRDKYMRAQMEPG
SAVGALCAQSIGEPGTQMTLKTFHFGGVASMNITLGVPRIKEIINASKAISTPIITAQ
LDKDDDADYARLVKGRIEKTLLGEISEYIEEVFLPDDCFILVKLSLERIRLLRLEVNA
ETVRYSICTSKLRVKPGDVAVHGEAVVCVTPRENSKSSMYYVLQFLKEDLPKVVVQGI
PEVSRAVIHIDEQSGKEKYKLLVEGDNLRAVMATHGVKGTRTTSNNTYEVEKTLGIEA
ARTTIINEIQYTMVVNHGMSIDRRHVMLLSDLMTYKGEVLGITRFGLAKMKESVLMLA
SFEKTADHLFDAAYFGQKDSVCGVSECIIMGIPMNIGTGLFKLLHKADRDPNPPKRPL
IFDTNEFHIPLVT"
BASE COUNT 1149 a 1002 c 1078 g 947 t
ORIGIN
1 atggtgaagg agcagttccg ggagacggat gtggccaaga aaacaagcca catctgtttt
61 ggaatgaagt cacctgagga gatgcgccag caggcgcaca tccaagttgt gagtaagaac
121 ctgtacagcc aggacaacca acatgccccc ttgctatatg gggtgctcga ccataggatg
181 ggtacgagtg agaaggatcg tccatgtgaa acctgtggga aaaacttggc tgactgtcta
241 ggccactatg ggtatatcga cctggagttg ccgtgttttc atgtagggta cttcagagca
301 gtcataggca tcttacagat gatctgcaaa acctgctgcc acatcatgct gtcccaagag
361 gagaagaagc agtttctgga ctatctaaag aggcccggcc tgacctacct tcagaagcga
421 ggactgaaaa agaaaatctc tgacaagtgc cggaagaaaa acatctgcca tcactgtggc
481 gcttttaatg gtaccgtaaa gaagtgtgga ctgctgaaaa taattcatga gaaatacaag
541 accaacaaaa aagtggtgga tcccattgta tcaaatttcc ttcagtcttt tgaaacagcc
601 attgaacata ataaagaagt ggagcctctg ctgggaaggg cacaggaaaa cttgaatccc
661 ttagtagttc tgaatttatt taaacgaatc ccagctgaag atgttcctct acttctgatg
721 aacccagaag ccggaaagcc gtctgatttg attctcacac gacttttggt gcctcctttg
781 tgtttcagac cctccgttgt gagtgatttg aagtctggca ccaatgaaga tgatctgaca
841 atgaaactga cagaaatcat tttcctaaac gatgttatta aaaagcatcg gatctcagga
901 gccaagaccc agatgatcat ggaggactgg gatttcctgc agctgcagtg tgccctctac
961 attaacagtg agctctcggg cattcccctc aacatggcac ccaagaagtg gaccagaggc
1021 ttcgtccaac gcctgaaggg aaaacagggt cgatttagag gaaatctctc aggaaagaga
1081 gtggattttt ctggcagaac agtcatctcg cccgacccca acctccggat tgatgaggta
1141 gctgtgccag ttcatgtggc caaaattcta acttttcctg agaaggtaaa caaagcaaac
1201 atcaatttct tgaggaaact ggttcaaaac ggccctgagg ttcacccagg agcaaacttc
1261 attcagcaga gacatacgca gatgaaaagg tttttgaaat acggaaatcg agaaaagatg
1321 gctcaagagc tcaagtatgg tgacatcgta gagagacacc tcatcgatgg agatgtggtg
1381 ctgttcaatc ggcagccctc gctgcacaaa ttgagcatta tggctcatct ggccagggtc
1441 aagccccacc ggaccttcag atttaatgag tgtgtctgta caccctataa tgctgacttt
1501 gatggtgatg aaatgaacct tcatcttcct caaacagaag aagctaaagc agaggccctt
1561 gttctgatgg ggactaaagc aaatcttgta accccgagga atggggaacc gctgattgct
1621 gctattcagg attttctaac aggtgcctat ctcctcactc tcaaggacac tttctttgat
1681 cgagccaagg cttgccaaat cattgcttca atactggttg gcaaggatga gaaaattaaa
1741 gttcgcctcc caccgcctac aatcctaaag cctgtcaccc tgtggacggg aaagcagatc
1801 ttcagtgtca tcctcaggcc tagcgatgac aatccagtga gggccaacct gcgaaccaag
1861 ggcaagcagt actgtggcaa aggggaagat ctctgtgcca atgattccta tgttacaatc
1921 cagaacagtg agttgatgag tggcagcatg gacaaaggaa ccctagggtc aggatccaag
1981 aacaatattt tttacatttt gctgcgagac tggggacaga atgaagctgc agatgccatg
2041 tcacggctcg ccaggctggc tcctgtctac ctgtctaacc gtggtttctc aattgggatc
2101 ggtgatgtca cacctggcca aggactgctg aaggccaagt atgagttgct gaatgccggc
2161 tacaagaaat gtgatgagta catcgaagcc ctgaacacgg gcaagctgca gcagcagcct
2221 ggctgcactg ctgaggagac cctggaggca ctgatcctga aggagctgtc tgtgatccgt
2281 gaccacgctg gcagtgcctg cctccgggag ctggacaaga gcaacagccc cctcaccatg
2341 gctctgtgcg gctccaaagg ttccttcatt aacatatcac agatgattgc ctgtgtggga
2401 cagcaggcca tcagtggctc tcgagtgcca gacggctttg aaaacaggtc cttgcctcat
2461 tttgaaaaac actcaaagct cccagctgcc aaaggctttg tggctaatag cttttattcc
2521 ggtttgacac caactgagtt tttcttccac acaatggccg gccgggaagg tctagtcgac
2581 acggctgtaa agacagctga aacgggatac atgcagcgaa ggcttgtcaa atctcttgaa
2641 gatctttgct cccagtatga tctgacagtc cgaagctcta ctggcgatat tatccagttc
2701 atttatggag gagatggctt agatcctgca gctatggagg gaaaagatga acctttggag
2761 tttaaaaggg ttctggacaa catcaaagca gtcttcccgt gtcccagtga gcctgctctc
2821 agcaaaaacg agctgatcct gaccacagag tccatcatga agaagagtga gttcctctgc
2881 tgccaggaca gcttcctgca ggaaataaaa aaattcatta agggggtctc tgagaagatc
2941 aagaaaacca gagataaata tggcatcaat gataacggca caacagagcc ccgtgtgctg
3001 taccagctgg accgcatcac ccccacccaa gtagaaaagt ttctggagac ctgtagggac
3061 aagtacatga gggcacagat ggagccaggt tctgcagtgg gtgctctgtg tgcccagagc
3121 attggtgagc caggcaccca gatgaccctg aagactttcc actttggagg tgtggcctcc
3181 atgaacatca ccctgggcgt gccccggatt aaagagatca tcaacgcttc caaggccatc
3241 agcactccaa ttatcacagc acagctagac aaggatgacg acgcggatta tgctcgcctc
3301 gtgaaaggga gaattgagaa aaccctcttg ggagagattt ccgagtatat tgaagaagtg
3361 tttcttcctg atgactgctt tattctcgtc aagctctccc tggaacggat taggcttctg
3421 agactggaag tgaacgctga gacagtgaga tattccatct gcacatccaa gctccgtgtg
3481 aagcccggtg atgtggctgt tcatggtgag gctgtggtgt gtgtcacccc cagagagaac
3541 agcaagagct ccatgtacta cgtgctgcag ttcctgaaag aggatctccc caaggtggtg
3601 gtgcagggca ttccagaggt gtccagagct gtcatccaca ttgacgagca gagtggaaag
3661 gagaagtaca agcttctggt ggaaggtgat aacctgcggg cagtcatggc cacacacggt
3721 gtgaagggca cccgaaccac ctccaataac acctatgagg tggagaaaac tctgggcatc
3781 gaggccgccc ggacaacgat catcaatgaa atccagtaca ccatggtggt gaaccacggc
3841 atgagcatcg acaggaggca cgtgatgctg ctctccgacc tcatgaccta caagggtgaa
3901 gtcctgggca tcactaggtt tggcctggcc aagatgaagg agagtgtgct gatgctggcc
3961 tcctttgaga agacggctga ccatctcttt gacgctgcct acttcgggca gaaggactct
4021 gtgtgtgggg tgtctgagtg catcatcatg ggaatcccaa tgaacattgg aaccgggctc
4081 ttcaagctgc ttcacaaggc tgacagggac ccgaaccctc ccaagaggcc cctgatcttc
4141 gacacaaatg aattccacat cccccttgtc acatag
//