LOCUS AF021139 1284 bp mRNA linear HUM 07-AUG-2000
DEFINITION Homo sapiens inward rectifier potassium channel (IRK1) mRNA,
complete cds.
ACCESSION AF021139
VERSION AF021139.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1284)
AUTHORS Rae,J.L. and Shepard,A.R.
TITLE Identification of potassium channels in human lens epithelium
JOURNAL (in) Civan,M.M. (Ed.);
THE EYE'S AQUEOUS HUMOR: FROM SECRETION TO GLAUCOMA: 69-104;
Academic Press, San Diego, CA, USA (1998) In press
REFERENCE 2 (bases 1 to 1284)
AUTHORS Rae,J.L. and Shepard,A.R.
TITLE Inwardly rectifying potassium channels in lens epithelium are from
the IRK1 (Kir 2.1) family
JOURNAL Exp. Eye Res. 66 (3), 347-359 (1998)
PUBMED 9533862
REFERENCE 3 (bases 1 to 1284)
AUTHORS Rae,J.L. and Shepard,A.R.
TITLE Direct Submission
JOURNAL Submitted (28-AUG-1997) Physiology and Biophysics, Mayo Foundation,
200 1st Street SW, Rochester, MN 55905, USA
FEATURES Location/Qualifiers
source 1..1284
/db_xref="H-InvDB:HIT000062562"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="lens epithelium"
gene 1..1284
/gene="IRK1"
CDS 1..1284
/gene="IRK1"
/codon_start=1
/product="inward rectifier potassium channel"
/protein_id="AAB88797.1"
/translation="MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCR
SRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCV
FWLIALLHGDLDASKEGKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM
VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLR
KSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDED
SPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEK
HYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSEN
GVPESTSTDTPPDIDLHNQASVPLEPRPLRRESEI"
primer_bind 1..27
/note="PCR primer designed from Mus musculus inward
rectifier k(+) channel IRK1 mRNA: GenBank Accession Number
X73052"
BASE COUNT 347 a 293 c 328 g 316 t
ORIGIN
1 atgggcagtg tgagaaccaa ccgctacagc atcgtctctt cagaagaaga cggtatgaag
61 ttggccacca tggcagttgc aaatggcttt gggaacggga agagtaaagt ccacacccga
121 caacagtgca ggagccgctt tgtgaagaaa gatggccact gtaatgttca gttcatcaat
181 gtgggtgaga aggggcaacg gtacctcgca gacatcttca ccacgtgtgt ggacattcgc
241 tggcggtgga tgctggttat cttctgcctg gctttcgtcc tgtcatggct gttttttggc
301 tgtgtgtttt ggttgatagc tctgctccat ggggacctgg atgcatccaa agagggcaaa
361 gcttgtgtgt ccgaggtcaa cagcttcacg gctgccttcc tcttctccat tgagacccag
421 acaaccatag gctatggttt cagatgtgtc acggatgaat gcccaattgc tgttttcatg
481 gtggtgttcc agtcaatcgt gggctgcatc atcgatgctt tcatcattgg cgcagtcatg
541 gccaagatgg caaagccaaa gaagagaaac gagactcttg tcttcagtca caatgccgtg
601 attgccatga gagacggcaa gctgtgtttg atgtggcgag tgggcaatct tcggaaaagc
661 cacttggtgg aagctcatgt tcgagcacag ctcctcaaat ccagaattac ttctgaaggg
721 gagtatatcc ctctggatca aatagacatc aatgttgggt ttgacagtgg aatcgatcgt
781 atatttctgg tgtccccaat cactatagtc catgaaatag atgaagacag tcctttatat
841 gatttgagta aacaggacat tgacaacgca gactttgaaa tcgtggtcat actggaaggc
901 atggtggaag ccactgccat gacgacacag tgccgtagct cttatctagc aaatgaaatc
961 ctgtggggcc accgctatga gcctgtgctc tttgaagaga agcactacta caaagtggac
1021 tattccaggt tccacaaaac ttacgaagtc cccaacactc ccctttgtag tgccagagac
1081 ttagcagaaa agaaatatat cctctcaaat gcaaattcat tttgctatga aaatgaagtt
1141 gccctcacaa gcaaagagga agacgacagt gaaaatggag ttccagaaag cactagtacg
1201 gacacgcccc ctgacataga ccttcacaac caggcaagtg tacctctaga gcccaggccc
1261 ttacggcgag agtcggagat atga
//