LOCUS AF020260 2422 bp mRNA linear HUM 10-MAR-1999
DEFINITION Homo sapiens WDR1 protein mRNA, complete cds.
ACCESSION AF020260
VERSION AF020260.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2422)
AUTHORS Adler,H.J., Winnicki,R.S., Gong,T.W. and Lomax,M.I.
TITLE A gene upregulated in the acoustically damaged chick basilar
papilla encodes a novel WD40 repeat protein
JOURNAL Genomics 56 (1), 59-69 (1999)
PUBMED 10036186
REFERENCE 2 (bases 1 to 2422)
AUTHORS Adler,H.J., Winnicki,R.S., Gong,T.-W.L. and Lomax,M.I.
TITLE Direct Submission
JOURNAL Submitted (20-AUG-1997) Kresge Hearing Research Institute,
University of Michigan, 9301 MSRB III, 1150 West Medical Center
Drive, Ann Arbor, MI 48109-0648, USA
FEATURES Location/Qualifiers
source 1..2422
/db_xref="H-InvDB:HIT000062508"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
5'UTR 1..111
CDS 112..1716
/function="protein-protein interactions"
/note="WD40 repeats; alternative splicing--72 amino acids
spliced from 3' end of human WDR1 protein encoded by
GenBank Accession Number AF020056"
/codon_start=1
/product="WDR1 protein"
/protein_id="AAD05045.1"
/translation="MPYEIKKVFASLPQVERGVSKIIGGDPKGNNFLYTNGKCVILRN
IDNPALADIYTEHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYEYQPFA
GKIKDIAWTEDSKRIAVVGEGREKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPY
RLATGSDDNCAAFFEGPPFKFKFTIGDHSRFVNCVRFSPDGNRFATASADGQIYIYDG
KTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSKIWDVSVNSVVSTFPMGS
TVLDQQLGCLWQKDHLLSVSLSGYINYLDRNNPSKPLHVIKGHSKSIQCLTVHKNGGK
SYIYSGSHDGHINYWDSETGENDSFAGKGHTNQVSRMTVDESGQLISCSMDDTVRYTS
LMLRDYSGQGVVKLDVQPKCVAVGPGGYAVVVCIGQIVLLKDQRKCFSIDNPGYEPEV
VAVHPGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAKGPVTDVAYSHDGAFLAVCD
ASKVVTVFSVADGYSENNVFYGHHEK"
3'UTR 1717..2422
regulatory 2382..2387
/regulatory_class="polyA_signal_sequence"
polyA_site 2402
BASE COUNT 592 a 625 c 680 g 525 t
ORIGIN
1 tgccgccttc cggctccagt ccccgggctc ggcctcggcg aggtgtaatt cgcagcgcgg
61 gccggccccg gaggctctcg gcgagcgcgg cgcggtaaca agtgggcgag gatgccgtac
121 gagatcaaga aggtgttcgc cagcctcccg caggtggaga ggggcgtctc caagatcatc
181 ggcggcgacc ctaagggcaa caattttctg tacaccaatg gaaagtgcgt catcctaagg
241 aacatcgaca acccagccct tgctgacatc tacacagagc acgcccatca ggtggtggtg
301 gccaagtatg cgcccagcgg attctacatt gcctccggag atgtgtctgg gaagctgagg
361 atctgggata ccacgcagaa ggagcacctg ttgaagtatg agtaccagcc tttcgctggg
421 aagatcaaag acattgcttg gactgaagac agtaagagga tcgccgtggt cggggaagga
481 agggagaagt ttggagcagt cttcctctgg gatagtggct cttctgtggg cgagattaca
541 ggacacaaca aagtcatcaa cagcgtggac atcaagcaga gccggccata ccggctggcc
601 acgggaagcg atgataactg cgcggcattc tttgagggac ccccattcaa gttcaagttc
661 acaattggcg accacagccg ctttgtcaac tgtgtgcgat tctctcctga tgggaacaga
721 tttgccacag ccagtgctga cggccagata tacatctatg acgggaagac tggggagaag
781 gtgtgcgcgc tgggcggaag caaggcccac gacggtggga tttacgcaat tagttggagt
841 cccgacagca cccatttgct ttctgcttct ggggacaaaa cttccaagat ttgggacgtc
901 agcgtgaact ccgtggtcag cacatttccc atgggctcca cggttctgga ccagcagctg
961 ggctgcctat ggcagaagga ccacctgctc agtgtctccc tgtccgggta catcaactat
1021 ctggacagaa acaaccccag caagcccctg cacgtcatca agggtcacag taaatcgatc
1081 cagtgtctga cggtgcataa aaacggcggc aagtcctaca tttactctgg gagccacgac
1141 ggacacatta attactggga ttcagagacg ggggagaacg actccttcgc tgggaaaggc
1201 cacacgaacc aggtgtccag gatgaccgtg gatgagtcgg ggcagctcat cagctgcagc
1261 atggacgaca ccgtgcggta caccagcctc atgctgcggg actacagcgg acaaggagtt
1321 gtgaaactgg acgttcagcc aaagtgcgta gccgtcggcc ccgggggata cgccgtggtc
1381 gtgtgcattg gacagattgt cctgctgaag gatcagagga agtgcttcag catcgacaac
1441 cccggctacg agcccgaagt tgtggcagtg caccccggcg gggacacggt ggcaattggg
1501 ggtgtggacg gcaacgtccg cctgtattcc atcctgggca ccacgctgaa ggatgagggc
1561 aagctcctag aggccaaggg ccccgtgacc gacgtggcct actcccacga cggcgccttc
1621 ctcgcggtgt gcgacgccag caaggtggtc acagtgttca gcgttgctga cggctactcg
1681 gagaacaatg ttttttatgg acaccatgaa aaataaagcg agcacctaaa caatgtgtgg
1741 agcataacta aaacccacag cccaaccaaa ccttgagaat gcgaaacatt ccagaggcag
1801 tagcctccaa agcacacaga gcccctggcc ccgccgcggc tctcactatc tgtcagggga
1861 ggttgtacag gtgaatgagc cggggggctc atgttcctgc ctgcagaaca tttctgtact
1921 agtgagaaga gggaatatgc attgcagttc agcaaagccg gaattctgtg ttgaacagat
1981 gtctgtctcc ctagtgtgtg actcacacct tgtggctgcc ttcagagcgc cacctccaga
2041 tcagatgggg acacacaacc cctggatatg tttcattgtc agattttgtg cttgatttta
2101 agaatggaat tgtgggtatc tttccttttt ttttaatgta tcttaactgt tgcctgtcag
2161 tgtttacaaa ctagtgcgtt gacggcaccg tgtccaagtt tttagaaccc ttgttagcca
2221 gaccgaggtg tcctggtcac cgtttcacca tcatgctttg atgttcccct gtctttccct
2281 cttctgctct caagagcaaa ggttaattta aggacaaaga tgaagtcact gtaaactaat
2341 ctgtcattgt ttttaccttc cttttctttt tcagtgcaga aattaaaagt aagtataaag
2401 caaaaaaaaa aaaaaaaaaa aa
//