LOCUS AF019563 3877 bp DNA linear HUM 26-JAN-1999
DEFINITION Homo sapiens DAP12 gene, complete cds.
ACCESSION AF019563
VERSION AF019563.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3877)
AUTHORS Lanier,L.L., Corliss,B.C., Wu,J., Leong,C. and Phillips,J.H.
TITLE Immunoreceptor DAP12 bearing a tyrosine-based activation motif is
involved in activating NK cells
JOURNAL Nature 391 (6668), 703-707 (1998)
PUBMED 9490415
REFERENCE 2 (bases 1 to 3877)
AUTHORS Lanier,L.L.
TITLE Direct Submission
JOURNAL Submitted (14-AUG-1997) Immunobiology, DNAX Research Institute, 901
California Avenue, Palo Alto, CA 94304, USA
FEATURES Location/Qualifiers
source 1..3877
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19q13.1"
/note="DAP12 genomic sequence predicted from the genomic
sequence of a segment of human chromosome 19q13.1,
deposited as Genbank Accession Number AD000833"
mRNA join(1..117,523..555,705..839,1021..1067,3651..>3716)
/product="DAP12"
CDS join(57..117,523..555,705..839,1021..1067,3651..3716)
/note="membrane protein; type I transmembrane protein
containing an ITAM sequence in the cytoplasmic domain"
/codon_start=1
/product="DAP12"
/protein_id="AAD09437.1"
/translation="MGGLEPCSRLLLLPLLLAVSGLRPVQAQAQSDCSCSTVSPGVLA
GIVMGDLVLTVLIALAVYFLGRLVPRGRGAAEAATRKQRITETESPYQELQGQRSDVY
SDLNTQRPYYK"
BASE COUNT 963 a 1026 c 971 g 917 t
ORIGIN
1 cgctgcgcca catcccaccg gcccttacac tgtggtgtcc agcagcatcc ggcttcatgg
61 ggggacttga accctgcagc aggctcctgc tcctgcctct cctgctggct gtaagtggtg
121 agttaggggc ttccgtggct gcctcccggg tccctgggct cagcttgggg cagggcaggg
181 agtggggtgg aacgagagaa ccaaaagtgg gtgttgggat gggagcaggt ccccaacctc
241 ccaaagcctg tgggtttctc ccagagccca agcccccaag ttttgtcgtc cgctacaagc
301 aggggagaag agacatctaa gtgtgttgcc acaggacaag ttgtgcagaa gtaacgcaca
361 tagtccggtg gcccagacgc cagccccctg agtcccgcca gacacgctct cccccttgct
421 aacctcttgg ctgtcaggat ccaccttccc tggcttctaa acttgcctcc cccacccccg
481 tcataactct gtgcctcagt ttaccttctt tttcctcctc aggtctccgt cctgtccagg
541 cccaggccca gagcggtagg cctagaccca gcagtccctc tctctacctc ccagagacct
601 ccctgtctcc gtctctccca caccctttcc aaacctccct gccgctgacc cccctcccca
661 cagttcccag cacacactga cctcccctga cccctgtgct gcagattgca gttgctctac
721 ggtgagcccg ggcgtgctgg cagggatcgt gatgggagac ctggtgctga cagtgctcat
781 tgccctggcc gtgtacttcc tgggccggct ggtccctcgg gggcgagggg ctgcggaggg
841 tgagtggggc tagcagggga catcctgagg acttgcctag atgggggtgg ggggctgggt
901 aaactcccag atctcaaaca tccaaaggga tggtaatgga ggtgctgatt tggaatgaca
961 aaacaccctc aactcaccac tctgcctgtc tctgcacccc acaacacccc tcacctccag
1021 cagcgacccg gaaacagcgt atcactgaga ccgagtcgcc ttatcaggtg agaaaaccag
1081 actgtcctcc tcacatttca ctcctgccag ggatatctgc cccagatact ccttcatgcc
1141 atcagaggga cctcaaagcc actctgccta aagcaccccc aaaccttgaa ggcacatggg
1201 acatctgtcc aaaactgggc cgaatgatca accacaagct tatggtcagc ttaaaatgtg
1261 tgaagagggg ctgggcacgg tgactcaaac ctgtaatccc agcactttgg gagacagagg
1321 cgggtggatc acttgaggtc aggagttcga gaccaacatg gtgaaaccct gtctctacta
1381 aaaatacaaa attagctggg cgtggtaacg catgcctgta atcccagcta cttgggaggc
1441 tgaggcagga gaatcctttg acccaggagg cggaggttgc agtgagccaa gatcacgcaa
1501 ttgcactcca gcctgggcaa caagaggaaa actctgtcaa aaaaaaaaaa gcgtgaagag
1561 ttaaaaagaa aaaaaaaagg gtggctttgc ctttgtaagt gtaaacacag gccttgccag
1621 aagtcaggcc aggaattttc tggaagaaac ccagccctag gacgactgat ttctgggaga
1681 cgctctcagt agggcagaga atgtcattca gccctacctt ggtaactcta aagagaggag
1741 tcctagaatc tcttttttgg gtttgaggac ccttcatccc tttgagaaac taagaaaatc
1801 tagactccca gaaaaatcta cacaaaaaat acaaaattgt gcatataatc tgagagcagt
1861 gtaaatgttc tttataatta aaaaaaattt ttttttggcc aggcatggtg gcacacacct
1921 gtaatcccag cactttggga ggccaaggtg ggtggatcac gaggtcagga gttcaagacc
1981 agccaggcca ggatggtgaa accccatctc tactaaaaat acaaaaatta gctgggcatg
2041 gtgtcatgcg cctgtaattc cagcttctca ggaggctgag gcaagagaat cgcttgaacc
2101 cagggggcgg aggttgcagt gagcctgggc gacagagtga gactccatct caaaaaaaaa
2161 aaaaagacag gggtctcact atgttgcccc agctggtctc aaactcccag tctcaagtga
2221 tcctcccgcc tcagcctccg aaaatcttgg gattacaggc tcaagcaacc atgctggttg
2281 agtattcttg aagctctttt ttctttctct actttaattt tttttttttt ttgagatgga
2341 gtctcattct gtcacccagg ctggagtgca atggtgtggt ctcagctcac tgcaacctcc
2401 acctcccagg ttcaagcgat tctcttgcct gagcctcccg agtagctgga actacaggtg
2461 catgccacca cacccggcta atttttgtat ttttagtaga gatggggttt cactatgttg
2521 gccaggctgg tctcaatctc ctgacctcgt gatccgccca cctttccctc ccaaagtgct
2581 gggattagag gtgtgagcca ccgcgcccgg ccttaatttt tttttttttt ttaaagtaga
2641 gataggttct cactatgttg cccaggctgg tctcaaactc ctgggctcaa gagatcctgt
2701 tacctcggtc tcccaaagtg ctgggattat aggcatgagt caccatgcct ggctgaagct
2761 ctttttaaaa actatagagt atacaagaga atctagtcat ctatccccct ctctgtcaat
2821 gttccttttt aaccctttag ggggtcatga gattctctaa gacctctccc ctgaagaatg
2881 cacgcccaga ctagtcatca tatatgattt tagggtttct gtctgaggcc tgcccctggg
2941 ggccacatag atcctccccc taccccaagt gtgaacactg ctgtgtgaag tctgatatat
3001 tgtctgcaac cagctttgcc tattcacctc acttgtggat aaagtttctt tgtgaagtct
3061 aagaatctca ggtttggctc tgtgatatcc agaagaccga ggggcccttc cagttactgg
3121 tggcagtgaa attttagggc aaagcattac ccggatgtat ttattccctc tgtggatgtg
3181 tctagcacct ataagtgcta aatgctgggg acacagtgac agagtttata tcctagttaa
3241 gacaaactta aagcaaatga acaaataaaa taattttggg aggcacagta aaggaaataa
3301 acaggctttt tttttttttt ttacagtggc tggagtgtgg ggggaagaaa ctacagaggg
3361 gaaattgaga aatgcctctc tgaggaggtg acgtgagctg agacttgaag ggagagggga
3421 tctaggggaa cagagtttta ggcagaggaa acagcacacg cagggaccct gaggctgggg
3481 cacactgatg aggcagagga gaagggggaa cattgaatgt acttgaataa aatccggatc
3541 tctttcatgg ctataaggct gaagaagctg ccaggggcct tgcaggccac tgggagaagg
3601 ctggatttta tttggtgggt cccttccact gatggccccc attcctttag gagctccagg
3661 gtcagaggtc ggatgtctac agcgacctca acacacagag gccgtattac aaatgagccc
3721 gaatcatgac agtcagcaac atgatacctg gatccagcca ttcctgaagc ccaccctgca
3781 cctcattcca actcctaccg cgatacagac ccacagagtg ccatccctga gagaccagac
3841 cgctccccaa tactctccta aaataaacat gaagcac
//