LOCUS AH007038 2435 bp DNA linear HUM 10-JUN-2016
DEFINITION Homo sapiens chromosome 20 homeodomain protein (Nkx2.2) gene,
complete cds.
ACCESSION AH007038 AF019414 AF019415
VERSION AH007038.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2435)
AUTHORS Furuta,H., Horikawa,Y., Iwasaki,N., Hara,M., Sussel,L., Le
Beau,M.M., Davis,E.M., Ogata,M., Iwamoto,Y., German,M.S. and
Bell,G.I.
TITLE Beta-cell transcription factors and diabetes: mutations in the
coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B)
genes are not associated with maturity-onset diabetes of the young
in Japanese
JOURNAL Diabetes 47 (8), 1356-1358 (1998)
PUBMED 9703340
REFERENCE 2 (bases 1 to 2435)
AUTHORS Furuta,H., Horikawa,Y. and Bell,G.I.
TITLE Direct Submission
JOURNAL Submitted (14-AUG-1997) Howard Hughes Medical Institute, The
University of Chicago, 5841 S. Maryland Avenue, MC1028, Chicago, IL
60637, USA
COMMENT On or before Jun 10, 2016 this sequence version replaced
AF019414.1, AF019415.1, AH007038.1.
FEATURES Location/Qualifiers
source 1..2435
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="20"
gene 1..2435
/gene="Nkx2.2"
mRNA join(1..364,1022..2435)
/gene="Nkx2.2"
/product="homeodomain protein"
exon 1..364
/gene="Nkx2.2"
/number=1
CDS join(106..364,1022..1584)
/gene="Nkx2.2"
/note="transcription factor"
/codon_start=1
/product="homeodomain protein"
/protein_id="AAC83132.1"
/translation="MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKR
AGPLGQGALDAVQSLPLKNPFYDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSK
SPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREH
LASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLPSPRRVAVPVLVRDGKPCHAL
KAQDLAAATFQAGIPFSAYSAQSLQHMQYNAQYSSASTPQYPTAHPLVQAQQWTW"
gap 577..676
/estimated_length=unknown
exon 1022..2435
/gene="Nkx2.2"
/number=2
BASE COUNT 467 a 738 c 646 g 484 t
ORIGIN
1 tccctccccc cactcccccc tcccccgccc gccggggcag gggagcgcca cgaattgacc
61 aagtgaagct acaactttgc gacataaatt ttggggtctc gaaccatgtc gctgaccaac
121 acaaagacgg ggttttcggt caaggacatc ttagacctgc cggacaccaa cgatgaggag
181 ggctctgtgg ccgaaggtcc ggaggaagag aacgaggggc ccgagccagc caagagggcc
241 gggccgctgg ggcagggcgc cctggacgcg gtgcagagcc tgcccctgaa gaaccccttc
301 tacgacagca gcgacaaccc gtacacgcgc tggctggcca gcaccgaggg ccttcagtac
361 tcccgtaagt agcaaaactt ggctgccgag gccgtggtcc cctccattcc tgcagccgca
421 gcccgggttg gacgctggga gtgaaagggg aaggggccat gtaagcccgg accccctcac
481 tcggatccgt agaaagattt ttaacacctg tataggatgt cctctgccct cctcttcaag
541 cctccttagt tccgggaaag aacttggtct ccaaaannnn nnnnnnnnnn nnnnnnnnnn
601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
661 nnnnnnnnnn nnnnnntgcc cacgtctcgc cggagaggaa accgcttaag ggcgccggag
721 cccttaaccc gcgatgatct tcagtgccac ttcccccccc aaattctcac ccacactatg
781 tgagcccctt gaaaggcgag cccctagccc ccactcctac ggatttccct ctttaccctg
841 ggaggtcccg acgtcttcgt caggcgtaga ggaaggcagg ggtcatggca aaggcagcgg
901 ggctgggctg ccaggcgcgg aggtccaggg tcgcacggag gatccagggt gctccgagtc
961 tggtgcaggc tgcgcgcggc ctccagacgc ctgacgcgct tctctctccc cctcccccca
1021 gtgcacggtc tggctgccgg ggcgccccct caggactcaa gctccaagtc cccggagccc
1081 tcggccgacg agtcaccgga caatgacaag gagaccccgg gcggcggggg ggacgccggc
1141 aagaagcgaa agcggcgagt gcttttctcc aaggcgcaga cctacgagct ggagcggcgc
1201 tttcggcagc agcggtacct gtcggcgccc gagcgcgaac acctggccag cctcatccgc
1261 ctcacgccca cgcaggtcaa gatctggttc cagaaccacc gctacaagat gaagcgcgcc
1321 cgggccgaga aaggtatgga ggtgacgccc ctgccctcgc cgcgccgggt ggccgtgccc
1381 gtcttggtca gggacggcaa accatgtcac gcgctcaaag cccaggacct ggcagccgcc
1441 accttccagg cgggcattcc cttttctgcc tacagcgcgc agtcgctgca gcacatgcag
1501 tacaacgccc agtacagctc ggccagcacc ccccagtacc cgacagcaca ccccctggtc
1561 caggcccagc agtggacttg gtgagcgccg ccccaacgag actcgcggcc ccaggcccag
1621 gccccacccc ggcggcggtg gcggcgagga ggcctcggtc cttatggtgg ttattattat
1681 tattataatt attattatgg agtcgagttg actctcggct ccactaggga ggcgccggga
1741 ggttgcctgc gtctccttgg agtggcagat tccacccacc cagctctgcc catgcctctc
1801 cttctgaacc ttgggagagg gctgaactct acgccgtgtt tacagaatgt ttgcgcagct
1861 tcgcttcttt gcctctcccc ggggggacca aaccgtccca gcgttaatgt cgtcacttga
1921 aaacgagaaa aagaccgacc ccccacccct gctttcgtgc attttgtaaa atatgtttgt
1981 gtgagtagcg atattgtcag ccgtcttcta aagcaagtgg agaacacttt aaaaatacag
2041 agaatttctt ccttttttta aaaaaaaata agaaaatgct aaatatttat ggccatgtaa
2101 acgttctgac aactggtggc agatttcgct tttcgttgta aatatcggtg gtgattgttg
2161 ccaaaatgac cttcaggacc ggcctgtttc ccgtctgggt ccaactcctt tctttgtggc
2221 ttgtttgggt ttgttttttg ttttgttttt gtttttgcgt tttcccctgc tttcttcctt
2281 tctcttttta ttttattgtg caaacatttc tcaaatatgg aaaagaaaac cctgtaggca
2341 gggagccctc tgccctgtcc tccgggcctt cagccccgaa cttggagctc agctattcgg
2401 cgcggttccc caacagcgcc gggcgcagaa agctt
//