LOCUS AF019225 2850 bp mRNA linear HUM 23-MAY-2001
DEFINITION Homo sapiens apolipoprotein L-I mRNA, complete cds.
ACCESSION AF019225 AF323541
VERSION AF019225.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 213 to 1470)
AUTHORS Duchateau,P.N., Pullinger,C.R., Orellana,R.E., Kunitake,S.T.,
Naya-Vigne,J., O'Connor,P.M., Malloy,M.J. and Kane,J.P.
TITLE Apolipoprotein L, a new human high density lipoprotein
apolipoprotein expressed by the pancreas. Identification, cloning,
characterization, and plasma distribution of apolipoprotein L
JOURNAL J. Biol. Chem. 272 (41), 25576-25582 (1997)
PUBMED 9325276
REFERENCE 2 (bases 1 to 2850)
AUTHORS Duchateau,P.N., Pullinger,C.R., Cho,M.H., Eng,C. and Kane,J.P.
TITLE Apolipoprotein L gene family: tissue-specific expression, splicing,
promoter regions; discovery of a new gene
JOURNAL J. Lipid Res. 42 (4), 620-630 (2001)
PUBMED 11290834
REFERENCE 3 (bases 213 to 1470)
AUTHORS Duchateau,P.N., Pullinger,C.R., Orellana,R.E., Kunitake,S.T.,
Naya-Vigne,J., O'Connor,P.M., Malloy,M.J. and Kane,J.P.
TITLE Direct Submission
JOURNAL Submitted (13-AUG-1997) Cardiovascular Research Institute,
University of California, San Francisco, 505 Parnassus Avenue, San
Francisco, CA 94143-0130, USA
REFERENCE 4 (bases 1 to 2850)
AUTHORS Duchateau,P.N., Pullinger,C.R., Orellana,R.E., Kunitake,S.T.,
Naya-Vigne,J., O'Connor,P.M., Malloy,M.J. and Kane,J.P.
TITLE Direct Submission
JOURNAL Submitted (16-JAN-2001) Cardiovascular Research Institute,
University of California, San Francisco, 505 Parnassus Avenue, San
Francisco, CA 94143-0130, USA
REMARK Sequence update by submitter
COMMENT On Jan 16, 2001 this sequence version replaced AF019225.1.
FEATURES Location/Qualifiers
source 1..2850
/db_xref="H-InvDB:HIT000062475"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="22"
/map="22q12.1-q13.1"
/tissue_type="pancreas"
CDS 213..1364
/note="apoL-I; high density lipoprotein-associated
protein; splice variant A; major form"
/codon_start=1
/product="apolipoprotein L-I"
/protein_id="AAB81218.2"
/translation="MSALFLGVRVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGT
MDPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDN
LARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSKLEDNIRRLRALADGVQKVHKGTTIA
NVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTIDYGKK
WWTQAQAHDLVIKSLDKLKEVKEFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARA
NLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDV
VYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQADQEL"
BASE COUNT 765 a 659 c 805 g 621 t
ORIGIN
1 gttgtgactt tccctttcga attcctcggt atatcttggg gactggagga cctgtctggt
61 tattatacag acgcataact ggaggtggga tccacacagc tcagaacagc tggatcttgc
121 tcagtctctg ccaggggaag attccttgga ggaggccctg cagcgacatg gagggagctg
181 ctttgctgag agtctctgtc ctctgcatct ggatgagtgc acttttcctt ggtgtgagag
241 tgagggcaga ggaagctgga gcgagggtgc aacaaaacgt tccaagtggg acagatactg
301 gagatcctca aagtaagccc ctcggtgact gggctgctgg caccatggac ccagagagca
361 gtatctttat tgaggatgcc attaagtatt tcaaggaaaa agtgagcaca cagaatctgc
421 tactcctgct gactgataat gaggcctgga acggattcgt ggctgctgct gaactgccca
481 ggaatgaggc agatgagctc cgtaaagctc tggacaacct tgcaagacaa atgatcatga
541 aagacaaaaa ctggcacgat aaaggccagc agtacagaaa ctggtttctg aaagagtttc
601 ctcggttgaa aagtaagctt gaggataaca taagaaggct ccgtgccctt gcagatgggg
661 ttcagaaggt ccacaaaggc accaccatcg ccaatgtggt gtctggctct ctcagcattt
721 cctctggcat cctgaccctc gtcggcatgg gtctggcacc cttcacagag ggaggcagcc
781 ttgtactctt ggaacctggg atggagttgg gaatcacagc cgctttgacc gggattacca
841 gcagtaccat agactacgga aagaagtggt ggacacaagc ccaagcccac gacctggtca
901 tcaaaagcct tgacaaattg aaggaggtga aggagttttt gggtgagaac atatccaact
961 ttctttcctt agctggcaat acttaccaac tcacacgagg cattgggaag gacatccgtg
1021 ccctcagacg agccagagcc aatcttcagt cagtaccgca tgcctcagcc tcacgccccc
1081 gggtcactga gccaatctca gctgaaagcg gtgaacaggt ggagagggtt aatgaaccca
1141 gcatcctgga aatgagcaga ggagtcaagc tcacggatgt ggcccctgta agcttctttc
1201 ttgtgctgga tgtagtctac ctcgtgtacg aatcaaagca cttacatgag ggggcaaagt
1261 cagagacagc tgaggagctg aagaaggtgg ctcaggagct ggaggagaag ctaaacattc
1321 tcaacaataa ttataagatt ctgcaggcgg accaagaact gtgaccacag ggcagggcag
1381 ccaccaggag agatatgcct ggcaggggcc aggacaaaat gcaaactttt ttttttttct
1441 gagacagagt cttgctctgt cgccaagttg gagtgcaatg gtgcgatctc agctcactgc
1501 aagctctgcc tcccgtgttc aagcgattct cctgccttgg cctcccaagt agctgggact
1561 acaggcgcct accaccatgc ccagctaatt tttgtatttt taatagagat ggggtttcac
1621 catgttggcc aggatggtct cgatctcctg acctcttgat ctgcccacct tggcctccca
1681 aagtgctggg attacaggcg tgagccatcg cttttgaccc aaatgcaaac attttattag
1741 ggggataaag agggtgaggt aaagtttatg gaactgagtg ttagggactt tggcatttcc
1801 atagctgagc acagcagggg aggggttaat gcagatggca gtgcagcaag gagaaggcag
1861 gaacattgga gcctgcaata agggaaaaat gggaactgga gagtgtgggg aatgggaaga
1921 agcagtttac tttagactaa agaatatatt ggggggccgg gtgtagtggc tcatgcctgt
1981 aatccgagca ctttgggagg ccaaggcggg cggatcacga ggtcaggaga tcaagaccat
2041 cctggctaac acagtgaaac cccgtctcta ctaaaaatac aaaaaattag ccgggcatgg
2101 tgcgggcgcc tgtagttcca gctaactggg cggctgaggc aggagaatgg cgtgaacctg
2161 ggaggtggag cttgcagtga gccgagatat cgccactgca ctccagcctg ggtgacagag
2221 cgagactcca tctcaaaaaa aaaaaaaaaa agaatatatt gacggaagaa tagagaggag
2281 gcttgaagga accagcaatg agaaggccag gaaaagaaag agctgaaaat ggagaaagcc
2341 caagagttag aacagttgga tacaggagaa gaaacagcgg ctccactaca gacccagccc
2401 caggttcaat gtcctccgaa gaatgaagtc tttccctggt gatggtcccc tgccctgtct
2461 ttccagcatc cactctccct tgtcctcctg ggggcatatc tcagtcaggc agcggcttcc
2521 tgatgatggt cgttggggtg gttgtcatgt gatgggtccc tccaggttac taaagggtgc
2581 atgtcccctg cttgaacact gaagggcagg tggtgggcca tggccatggt ccccagctga
2641 ggagcaggtg tccctgagaa cccaaacttc ccagagagta tgtgagaacc aaccaatgaa
2701 aacagtccca tcgctcttac ccggtaagta aacagtcaga aaattagcat gaaagcagtt
2761 tagcattggg aggaagctca gatctctaga gctgtcttgt cgccgcccag gattgacctg
2821 tgtgtaagtc ccaataaact cacctactca
//