LOCUS AH006174 14090 bp DNA linear HUM 10-JUN-2016
DEFINITION Homo sapiens chromosome 3 biotinidase (Btd) gene, complete cds.
ACCESSION AH006174 AF018630 AF018631
VERSION AH006174.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 14090)
AUTHORS Knight,H.C., Reynolds,T.R., Meyers,G.A., Pomponio,R.J., Buck,G.A.
and Wolf,B.
TITLE Structure of the human biotinidase gene
JOURNAL Mamm. Genome 9 (4), 327-330 (1998)
PUBMED 9530634
REFERENCE 2 (bases 1 to 14090)
AUTHORS Knight,H.C. and Wolf,B.
TITLE Direct Submission
JOURNAL Submitted (12-AUG-1997) Human Genetics, Medical College of
Virginia, 1101 East Marshall Street, Sanger Hall Room 11-002,
Richmond, VA 23298, USA
COMMENT On or before Jun 10, 2016 this sequence version replaced
AF018630.1, AF018631.1, AH006174.1.
FEATURES Location/Qualifiers
source 1..14090
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p25"
gene 1..13506
/gene="Btd"
regulatory 1..565
/regulatory_class="promoter"
/gene="Btd"
/inference="non-experimental evidence, no additional
details recorded"
misc_feature 12..15
/gene="Btd"
/note="consensus methylation site"
misc_binding 85..90
/gene="Btd"
/note="GC box"
/bound_moiety="Sp1"
misc_feature 207..210
/gene="Btd"
/note="consensus methylation site"
misc_feature 210..217
/gene="Btd"
/note="Inr sequence"
misc_feature 246..249
/gene="Btd"
/note="consensus methylation site"
misc_binding 249..255
/gene="Btd"
/inference="non-experimental evidence, no additional
details recorded"
/bound_moiety="HNF-5"
misc_feature 312..319
/gene="Btd"
/note="Inr sequence"
misc_feature 416..423
/gene="Btd"
/note="Inr sequence"
regulatory 423..427
/regulatory_class="CAAT_signal"
/gene="Btd"
misc_binding 483..488
/gene="Btd"
/note="GC box"
/bound_moiety="Sp1"
misc_feature 510..517
/gene="Btd"
/note="octamer binding sequence"
mRNA join(566..644,4658..4922,11144..11293,12005..13506)
/gene="Btd"
/product="biotinidase"
exon 566..644
/gene="Btd"
/number=1
5'UTR 566..600
/gene="Btd"
CDS join(601..644,4658..4922,11144..11293,12005..13177)
/gene="Btd"
/EC_number="3.5.1.12"
/function="hydrolyzes biocytin to the vitamin biotin and
lysine"
/note="biotin-amide amidohydrolase"
/codon_start=1
/product="biotinidase"
/protein_id="AAC21679.1"
/translation="MAHAHIQGGRRAKSRFVVCIMSGARSKLALFLCGCYVVALGAHT
GEESVADHHEAEYYVAAVYEHPSILSLNPLALISRQEALELMNQNLDIYEQQVMTAAQ
KDVQIIVFPEDGIHGFNFTRTSIYPFLDFMPSPQVVRWNPCLEPHRFNDTEVLQRLSC
MAIRGDMFLVANLGTKEPCHSSDPRCPKDGRYQFNTNVVFSNNGTLVDRYRKHNLYFE
AAFDVPLKVDLITFDTPFAGRFGIFTCFDILFFDPAIRVLRDYKVKHVVYPTAWMNQL
PLLAAIEIQKAFAVAFGINVLAANVHHPVLGMTGSGIHTPLESFWYHDMENPKSHLII
AQVAKNPVGLIGAENATGETDPSHSKFLKILSGDPYCEKDAQEVHCDEATKWNVNAPP
TFHSEMMYDNFTLVPVWGKEGYLHVCSNGLCCYLLYERPTLSKELYALGVFDGLHTVH
GTYYIQVCALVRCGGLGFDTCGQEITEATGIFEFHLWGNFSTSYIFPLFLTSGMTLEV
PDQLGWENDHYFLRKSRLSSGLVTAALYGRLYERD"
intron 645..>1000
/gene="Btd"
/number=1
misc_feature 709..712
/gene="Btd"
/note="consensus methylation site"
misc_feature 751..754
/gene="Btd"
/note="consensus methylation site"
misc_feature 767..770
/gene="Btd"
/note="consensus methylation site"
gap 1001..1100
/estimated_length=unknown
intron <1101..4657
/gene="Btd"
/number=1
misc_binding 4375..4384
/gene="Btd"
/bound_moiety="C/EBP"
misc_binding 4620..4626
/gene="Btd"
/bound_moiety="C/EBP"
misc_binding 4638..4646
/gene="Btd"
/bound_moiety="Ap1"
exon 4658..4922
/gene="Btd"
/number=2
intron 4923..11143
/gene="Btd"
/number=2
exon 11144..11293
/gene="Btd"
/number=3
intron 11294..12004
/gene="Btd"
/number=3
exon 12005..13506
/gene="Btd"
/number=4
3'UTR 13178..13506
/gene="Btd"
/note="3'UTR"
regulatory 13474..13482
/regulatory_class="polyA_signal_sequence"
/gene="Btd"
BASE COUNT 3680 a 3236 c 3134 g 3940 t
ORIGIN
1 cttccctccc tcccgggcgc taaaaggaaa accccccgac ccccatcgcc catttctact
61 cgtctccaag acaacatcgc ggtccccgcc agcttccgta ggagcctttc attccaggaa
121 ggtccatcgt acttgcgttt tcagggcctg agcgatgact ttagcaccag acacctgctc
181 ctcgctgcgc tctgcgaagt tactgtccgg catcttccac cgaaaagctc taagcactca
241 cgcagccggc aaacaagcgg aatcatccag caaggcaaac gcgaagtcgg cagcacgcca
301 cctctggtac tgcacctctg acggacagga gggcaaccaa ctgccttaaa caacgggaag
361 gaagaggcgg tctaaattcg tccacttccc gggagaggtg agaatgtaaa cacgcgcatt
421 ctccaatcag aactgcgctc tcttctcggc tcctccattc gcgcgccaga atgccagagg
481 gaggcgggac tagcaggaga ttgctgccta tgcaaagcag gtaagaagcc gaactctgag
541 gcctctcgcc attgtctccg agtcggccag ctggagcgtt ttcggggctg taaagggaga
601 atggcgcatg cgcatattca gggcggaagg cgcgctaaga gcaggtacgg agggggcgtg
661 gtgcggcgcg gagggggtgt ggtaagggcg tgcggtccag accccgcccc gggcgcccag
721 ttggacttgg ggagggctgc gcaaaggctg ccgggagctg ggaagcccgg cgcgcgtcgt
781 ttgctggggc tgtttgtgcg ttgctgctgt gctaccgcgt tgcgttttct aggcatttac
841 ttacacgctt tgtggtttac gctctcataa ccttgtggtt ttatagtcct taaattattg
901 tagcgcacgt tacttaaatc cagaagcaga tgtgtacccc agcaagagat aaaatgacgc
961 tcagagtcag tagatccaga ccgtgcctga gatcctgaat nnnnnnnnnn nnnnnnnnnn
1021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
1081 nnnnnnnnnn nnnnnnnnnn tctcactggc tgctcttatg atccagaatg gaagaggatg
1141 aggacaaatg cagggggatg ttaggagacc actaagcagg tccctgtcat ttctctctct
1201 gtgattcctt ttgctgccac tttctccttg tccccttggc tccagccccc tgctgtcctt
1261 gctgtttctt gcacccgccc gtgaggcatg ctcctgcctc aggctctctg cctgccgtgc
1321 tctcacctcg cagacccacg tgatttcctc ccgaaccccc ttcaggcctc ggtccaaaca
1381 tcaccctctc atcgaggtct tccttgacca cactgcttaa aattgtcccc ctcgcctcac
1441 cttaccacct tcactgcctc atttctcctt tgtgcttaat caccatctca cacagttatc
1501 cagagcacga gccccacgag gaagggtctg tcttgtccac tgttggaccc ctgacaccta
1561 acccctgggg ctggcccaca gttgggaatt gcatggctgt ctgaagccag caccttcctg
1621 gttctgctgt tccctggaag tggggttcag tacaccccac gagccaaggc cctcatctca
1681 gagggcgtgc acatggttgc ctcaattgtg ctttcacact ggacccttcc tgcagtttac
1741 tctcctatgt cagatgccct tcaatgaaag caagtacatt gccaccttgt cacacctcta
1801 gttaccattt tctttatggt ccaggtcctg accagctcta aagatgggtc agctgctgta
1861 tttccaagaa ccccatgact tccagggccc cttgttccca ggaaggcccc gcaccccagt
1921 cgtcccgtgc ataacctcac gggccagcac ctggtagctg ctggaaggct tctgggggat
1981 gcctgggccc ctccagccct acctctagtc ctgccacttt acaactgagc acctcccgct
2041 gctgcctgct gaacccttca gagtccttgc cacaggccct atttactttt tcctgagaag
2101 gtatgtgtga tgccaaagag agaaaagcag catttgctaa tttgggtaaa atgtttcttt
2161 gggaagggca aattgatgta cagttgtccc tcagtatctg ttgggactgg ttccaggacc
2221 ccgtggatac cgaaaccctc agatgctcaa gtcccttata tcaaatggtg tagaatttac
2281 atgtaaccta aacacttcct cctgtacact ttaaatcatc tctagatccc ttacactacc
2341 taatacaaac taaatgctat ataaataatt gttatactgt attttttaaa ttgctattat
2401 tttttattgt tgtgctatta tttttattgg gctccctcct ccccctccca ccccagtaat
2461 ttcaatccaa ggttggtgga atccatggat gcagaaacaa tggatactga gggccggctg
2521 actagaccta tttttattgt aattactcat tctcttctac ctcattaagc ttggttcttt
2581 caagcatgaa tacctggttg aatctgcata acctcttatt atcgacctac ctttgttcac
2641 acacaaatga ttgccactta gagctctcct accgggctcc ttttgtaaaa taaattttat
2701 cttctccaga tagaaagaaa tgtgatacct tgcggatttt gcggtttcct tgttttgctg
2761 gattgcaagt cctttagaca taaacaaatg ttctgtaccc cgacatcggt ggtacccagc
2821 tctcagttga gaaagagatg taatgtgaat gccactcttg gccccaggca ctcctcactt
2881 gcccccactg gggactggtt cataccctcc tctcctggcc tcagtttcca tacctcttag
2941 tgaggccttt gcgttatact tcagaaatat tgtcagtatg actttgaaga tgaaagtttg
3001 cccccaaaat cactctctgt tatcattgtg aaaccagaga tggaatggaa aaatgggttt
3061 ctgagacatt ttaaattatt ccttgcttgt ctttagaggc aaaattcaga taagaaagct
3121 tatcaattat acttttgttt ctactcaaaa actcatgact gctcactcaa agactccttg
3181 ttcttatctt aaaacattgt ttacagtgtc ccagatgaat ggcaacaaat cctggggttt
3241 ggtgtttgga tggtacattt ccctggggaa agaaataaca gtttgagatg gaacggggtt
3301 ggggtgggag aatacttctc attctgagga atatttaatt ttgccaagat gagcatttct
3361 agttcttagt ctgttgacga aaagagctat ggtttgtttc tggaactttt gataaaaaat
3421 aaagaaattt gtagcctggg gagtttggtt ttaaaatgca aacacaggag ttatgagttg
3481 agacttggac agggtgtcat tttcttttta aagggcagca atatgattct ttgatttgtc
3541 tttgttatct tgacttttaa tccggattcc tgggcagttg ttcagcccca ggacatctcc
3601 atgggcaggt ggcctggcct tggcacacta cccagtaaat ctctgcctga gaggacgctt
3661 tagctgggag gccaggctga tttttaaagg cagaattgga ctatttactc taaaacagta
3721 atgcacactg tttagaaaga aacattccta ttctgggagg aaggaggaga cacacagaag
3781 tatcatttat ttctagtctt ttctggtaga agctatgaag ctgagtttac tctctggaaa
3841 tttgtagttt attttctaga aaattgcatt ttatcactgc aaaaaggatt ttatttccaa
3901 atgagtaggc ttttgagcaa gagttttgga gtcacagaga tggggttaag aaagtgataa
3961 tgtgcaatgg cgattctcaa gttcaaggag aaaaaataac atgcttttat tgggatactt
4021 tgcttgtcta taaaagaaag tagctattgg catttatgta gaagtcagca gtttcttggc
4081 accaaataaa taattttgtg ctgaataaag ggagagttat ccatagtatt tattactaac
4141 caaagaaatg cagggagaat tgtaattcat taggttttga tggccaggaa agccaagctg
4201 tgttattagg gtcatgacaa tcacagacat tacggatggc tgacctgtag tatggataga
4261 gggcagaggg tagagtgtga aatatatcac agaattatgt caaataatct ggatagttac
4321 tactgcttaa aatctaagtg cacagctaga aaagtgggta gtgacgcact acagtcttgc
4381 tgaacactgg gtaagaaaat catagcaaac gttgagtctg ttttggaaat gttctaaaac
4441 cagactatta acacagtgag ccattttaaa tgtggcttgc tacgtgtttg gagagaaaca
4501 catactcttt tattaggaac atgaaacaaa ctctttgagc cgcagtatca ctgcgagtga
4561 gtttaattgc tgggattaat aaatcacagc tgcaaacgtt aaattcttgg caggattctt
4621 tattcagctg ttttcccctt gccccattac attccagatt tgtggtctgc attatgtctg
4681 gagccagaag taagcttgct cttttcctct gcggctgtta cgtggttgcc ctgggagccc
4741 acaccgggga ggagagcgtg gctgaccatc acgaggctga atattatgtg gctgccgtgt
4801 atgagcatcc atccatcctg agtctgaacc ctctggctct catcagccgc caagaggcct
4861 tggagctcat gaaccagaac cttgacatct atgaacagca agtgatgact gcagcccaaa
4921 aggcaagaat gctcctcgga acctgagttt ctctcataca gagcagattg ctctttaccc
4981 cttgatcagt ggttgggtaa tcccaggctt cctaccaccc tctgaaaaag catccaggta
5041 gttaacctga gttgagttag tcagttgaat taggagcctt acccctcaga gagtggtccg
5101 tggaccggca tcccctggga gcttgttaga aatacaaaat cttgggcggc accccagacc
5161 tactgaatca gaatgtgcat tgcagcagga tccccaggtg atgctttcac atggcaagta
5221 tgagaagccc aggactagat ccccagttct caagtgtggt tgtacataag aatcacgagg
5281 taagtggtaa acactatggc tgcccgggtc ctggagagtc cgttgtaatt ggtgtggaag
5341 gggtgtggac tggcactggg attgttttaa ggctccccag tgcagtctaa tgtgcagaaa
5401 aaatttgaaa gatgactggg cgtgatgacc tctctgagtc attcgaagct tcactgaagt
5461 agtaagcatc tgcaagaatg ccgtttgctc ccttcagact gtttgaggct cgtttccggt
5521 ctctatgtcg gactacgatc agtctgagac cttcgcccag atagaactga ccccaaactg
5581 acaaagggaa ggtcagtgcc agcctttgtg aaggcttcct ggttggcctg aatttcctgc
5641 tcccttcagg aagggtgggg acaaaggaga ggcccccctg ggggcaaaga gggaaatatc
5701 agaggttgcc taagaaaatg ccctgctgga aaacacaaac ccgaagggaa gtttgggctg
5761 taactctggt ggcagggtga ccaagcgcag ctgcttgagg aagccctgct gtgcctcaac
5821 aggatgtaaa ctcattgtga gcaacacttt cctgctctct gtgaacttaa agggcagaac
5881 cagcaggtcc tgccccaaac agtccctgcc ttagagcagg gtggtcggga tggcctggac
5941 agccacagca attaaaaaat tgcaacattt taaaatttta gtctataata tatatacaaa
6001 ggctatgtgt atggggtggg ggggtgtttg ggggcagggg gtgtgtatgt gtgtataaca
6061 tgatgttgaa agggaacttg aagacttggt ccagcttctt ttttttcaac caagaccaac
6121 ttttgcaagg gtgacacttt tctttagtcc caacctgaca tacggtttct ccttgaacac
6181 cttcagtggc tcagactcac aggtccgttt gttccaatgg tgggaacttc tgaacaggtc
6241 ttcctttcaa tgagcagcag tcagcctccc cgtaactgcc accacgattc tatcgtcaga
6301 gctaaaggga gcaggaccgt gtcccttatc acggcatgcc atcttctcca cctttgagga
6361 cagctgtcat gatccccctg gcatctgtcc cccaggctgt atcctcagtc ccttccacag
6421 ttccttagga gactcagttt ccaaaccttc tactgaagac ttccatgttt tctctgtgct
6481 cagaactgta tgcagctatc ccgattctgt ctaataaggg cagggtagag aactctcacc
6541 tgtcgcattc tagatgttgt ccccagaaaa ctgctggcag ccacatgtct cattatgggt
6601 gtataaggca cttgctgtca actaaaacac cttttcacat gagcagacac acatgctgcc
6661 attgccatcc tgtacttata aattataaag gtgattgatt taagctgagg gcaagacttc
6721 acatttatgc tgttaaattt catcattcca gcctgttggg ctatttaggg atctttactg
6781 acatcccaag tatcagttac ctttacgtca ttcacacata tgatacacac ctcatttatg
6841 tctatgctga agtcagtgta aaaaaacccc aggctgtgcc ctcagacctc ctgatgacac
6901 tgatctccta gagggcaggc attctcttga tagagatgtt tgcctgcatg gcactgagtc
6961 cagcacctga aatgtcatct gcctcttgct tccctcccct atccaccgga ccattctgag
7021 acatttggca aatgacacac tgaaacccag actgtggctg tagaattctc ctgcattcac
7081 ctttcaataa tctgccccca gaggaaacac ttaacacggt tttgttgaaa ccacgccagc
7141 tgcacagcat cactccgtct ctatttgttt tccaggggcc aggattaagc tgttgatatg
7201 atcactttta gaatttacag atatctcagc tcccatacgt ggttatatgt tttttatttg
7261 tttgttttcc agcagcactt ttattttcct tacacgatga catgttgctg gggcctattg
7321 ttctcacata acagtagaaa accaaaattt gttgtcatct cttcaaagaa tcgagaattg
7381 catacagaaa aaccttacat aaattaaaag gatgaataca tttacaggtg taaatgcaaa
7441 ccactttcaa ctcagacaag taacagccca tggtgttctg gcagaaaaca tcagctaaga
7501 aaggaaactg ggtcctaagt cttggacttt ccaaccctta cagaccggca gaacagaaac
7561 aactggttca ggagcccttg ccagcctcca gagaaatccc agaacacgca gccctgacgt
7621 attaataccc tgcacagatc agagactgct ggccacgcag actcaccaag ccacagactt
7681 gtcttccaca agcactttct tatcttagcc acaaagtgac caagccacat gtactaaggg
7741 ttgaaatcaa agatatgtac agggtattaa gcaaatctgg ttatatgttt taaaacaact
7801 tctaagacaa attgatggca agtttgtgtg aaagttttat atcaaagttg ttataagagg
7861 ttcctgagca aaccaattga aatacagtca tgcattgctt aatgacaggg atatgttctg
7921 aaaggatgca tcattaggcc attgtgtcat tgtgcatgca tcatagcatg tacttacaca
7981 aacctacatg gtacggccta ctatgcgcct aggctatatg gtatggccca ttgttcctag
8041 gctataaacc tttacagcat attactgtac tgaacactgt aggcagttgt aacaagtggt
8101 aagcatttgt atatgtaaac atagaaaagg tacaataaaa attcagtatt ataatcttat
8161 gggaccacca tcacatatgt ggtctgtcat tgaccaaaat gtcatcatgc agtgcatgac
8221 tatatttctg tctcagtagg ggcattcata ggggaaaaac ggagtctagt ttcaagatga
8281 ttaggctggg cagtcacttg ggattgtaac cttcattcct cagaaggaag gggttcttga
8341 tctcattgag atctaccaga aaattgctga agccatttat caagaatgca acttacttcc
8401 tagataggat tactcatcac atcagaccca aaattttgcc cagctcaggt ttggttcctc
8461 tcctcattcc tggttgataa taatctagta tgtatacata atttaaatgt tattctccat
8521 gaaaaaccaa agttttgttt ttaataaaga aaaatgtcta tccaaatata attttcaaaa
8581 atctgaaaag atgactcata caaatataga atgaataaag cttttattta attcattaat
8641 taaggaacca gtaagatggt aaagctggtt caaaggaaaa ttcaaggaat ggaaatgtgt
8701 atatcagtca gtccagtgat tgttgaaatg aatttcctaa tagatgcaaa actgggtaat
8761 gtcctatagg gcaaaacatt gtaatctttg aggtgatctt ttaaatagca aagtcaaacg
8821 gtggtacatt ctccagctaa ttaaagaata attgagtgag cctattaaac agtaccctag
8881 tataatttgg aaaggctgca tctccatctt gccttatttt taggtttgag ataatttttc
8941 tttacatggt cattgctaag tgtgcaatga gatgatactg tactggaagg aacatacatt
9001 ggtatagtat ttctggaaag cagtttggca gtgtgtgtta agaacttaaa agtttaattt
9061 ttaggccagg tgctgtggct catgcctgta atcccagcat tttgggggtc caaagcgggc
9121 ggatcacttg aggtcaggag tttgagacca gcctgatggt gaaaccccat ctccactaaa
9181 aatacaaaat ttagccaggt gtggtggcgc atgtctgtaa tcccagctac tcaggaggct
9241 gaggcacgag aattacttga acccaggagg cggagattgc agtgagccga gatcacaaca
9301 ctgcactcca gcctgggcga cagaccaaga ctctctctca aaaaacaaaa caaaaattaa
9361 aactctaatt tttataccct ttgatccagt aatttcactt gtaagacttt attccaaaga
9421 aataatcaaa agatgcaatc aaagatttgt gtgaagtgta taattatgca ataagtgttt
9481 tgagcacact atgcagatgg tcaccacagt tttcttttta ttacaaaaag ttgggaacac
9541 ttcaaattcc aataatagag gataaattat ggcgtcctct taaatatgat gtggccccat
9601 tacaaatgga tttttgaaag tttttttttt ttcctttttt ttttgtggtg gagtttcact
9661 ttgtcaccca ggctggagtg caatggtgcg atctcagctc accgcaacct ctgcctcccg
9721 ggttccagtg attctccagc ctcagcctcc tgagtagctg ggattgcagg tgcccgctac
9781 catgcctggc taatttttgt atttttagta gagacggggt ttcatcatgt tgggcaggct
9841 ggtcttgaac tcctgagctc aggtgatctg cccacctggg cctcctgaag tgctgggatt
9901 acaggcgtga actgccatgc ttggccgtat tttttaaagt tcttaatgag ggaagtcaag
9961 atgtaaaacc atatatttat tattatctcc attatataca cacatacatg tatacagaga
10021 gaaaaagtaa tgaaaataac caaaatatta acaataagta tctgtgttat agaattatga
10081 ttgttttttc ccgttttcca aattttctac agtaaaactt ttgaagcttt tataaccagg
10141 aaaaaaattt aaaagtttgc aatgcattcc agaaataagt gtctcaaact ttgctaattt
10201 gaattgttca tgccttctct gcctgccttc tccaccttcc tccctggggc tggtgttccc
10261 ggcttgacat tttaaaccct gtaagtggag agcagtggaa gaatgatgcc ccagccctga
10321 gagctgaggg cggccctgtt tgtattttct taggttgctg tagatgtcac agggagttcc
10381 gggccatcac agccagggaa cacaggatgt tgccaggtgt gggaaaaggc ctttagggtg
10441 gtcagagtcc cgaagggagc ctcctaattc ccagttgggg aatggagatt tcaagcgagt
10501 tcttgtttcc aggctgagat gagcacactt gcctcttacc cactggccca gtggatccta
10561 accttggcta caaatgagaa tcacccgggg gacctttaaa caaacactgt tgccactatc
10621 ccacccacag tcaatcaaat cagactttgt aggggtggtc ccggcatcag tggtttttca
10681 gaagttcctc aactgattta aatgcacaat ggaagttgac aaccaccaga ctgaagatac
10741 cacgtgtgtt aatgggccca atgtattcaa ggcccagtag ttggccccat ctcccctggt
10801 atcctaagaa ctctaaatcc tttctagcta ttcgcttgtc aaactcctga gcttactttc
10861 aatggagctt acacattccc tccttccctc acatgacccc aggcacagtt aatggttgtt
10921 cctagaggac tttgtctttg ttccttgggg atcaggtgga gtgagacagt atccccaaga
10981 ctaagatctc tgaggagagt aaagacacca tctctgtgcc tctggttcct gctacagagt
11041 aacttcctga tggttgccaa aagaatgaac agaagaatga atgaatgcag cggttcttcc
11101 tgccatctga taacagacta ttctttgatg ttttcatttt caggatgtac agattatagt
11161 gtttccagaa gatggcattc atggattcaa ctttacaaga acatccattt atccattttt
11221 ggacttcatg ccgtctcccc aggtggtcag gtggaaccca tgcctggagc ctcaccgctt
11281 caatgacaca gaggtgattc ctgccttttt cctcagtagg ctgagggtac acagaggtga
11341 tctaagtcag ggaccagaag ctgtgacatg ttaactaaga ttgataggag accttaacat
11401 ccccaaaatc caacccaaac tcccaaagat ccatgtgcca catgttcatt ccattaaaga
11461 atgtctgacg ttacaaggca gttattcatc tatggatctt tccatttatt aattacacaa
11521 taaatacagg aatgtatact taaaccaaac caaaagtaaa aaaagaaaag ttcatcttca
11581 ccacagcctg cacctcatcc catgcccttg cttagagaaa ctgccatcaa caatttgatg
11641 tgcattcagt tgtattcttt tctatgcatt tcatagttat tgacatcctc tttttttttt
11701 tttttttgag atggagtctt actctgccac ccaggctgga gcgcagtggc gcgatctcgg
11761 ctcactgcaa gctccgcctt ctgggttcac gccattctcc tgcctcagcc tcccgagtag
11821 ctgggactac aggcatccac caccacgccc ggctaatttt ttgtattttt agttgagatg
11881 gggtttcacc gtgttagcca gggtggtctc aatctcctga cctcatgagc cacccgcctc
11941 agcctcccac agtgctggga ttacaggcaa aaacctcatt tatttacacc tttttttcct
12001 ctaggtgctc cagcgcctga gttgtatggc catcagggga gatatgttct tggtggccaa
12061 tcttgggaca aaggagcctt gtcatagcag tgacccaagg tgcccaaaag atgggagata
12121 ccagttcaac acaaatgtcg tgttcagcaa taatggaacc cttgttgacc gctaccgtaa
12181 acacaacctc tactttgagg cagcattcga tgttcctctt aaagtggatc tcatcacctt
12241 tgataccccc tttgctggca ggtttggcat cttcacatgc tttgatatat tgttctttga
12301 ccctgccatc agagtcctca gagactacaa ggtgaagcat gttgtgtacc caactgcctg
12361 gatgaaccag ctcccactct tggcagcaat tgagattcag aaagcttttg ctgttgcctt
12421 tggcatcaac gttctggcag ctaatgtcca ccacccagtt ctggggatga caggaagtgg
12481 catacacacc cctctggagt ccttttggta ccatgacatg gaaaatccca aaagtcacct
12541 tataattgcc caggtggcca aaaatccagt gggtctcatt ggtgcagaga atgcaacagg
12601 tgaaacggac ccatcccata gtaagttttt aaaaattttg tcaggcgatc cgtactgtga
12661 gaaggatgct caggaagtcc actgtgatga ggccaccaag tggaacgtga atgctcctcc
12721 cacatttcac tctgagatga tgtatgacaa tttcaccctg gtccctgtct ggggaaagga
12781 aggctatctc cacgtctgtt ccaatggcct ctgctgttat ttactttacg agaggcccac
12841 cttatccaaa gagctgtatg ccctgggggt ctttgatggg cttcacacag tacatggcac
12901 ttactacatc caagtgtgtg ccctggtcag gtgtgggggt cttggcttcg acacctgtgg
12961 acaggaaatc acagaggcca cggggatatt tgagtttcac ctgtggggca acttcagtac
13021 ttcctatatc tttcctttgt ttctgacctc agggatgacc ctagaagtcc ctgaccagct
13081 tggctgggag aatgaccact atttcctgag gaaaagtagg ctgtcctctg ggctggtgac
13141 ggcggctctc tatgggcgct tgtatgagag ggactaggaa aagtgtgtgg tctgtggggc
13201 ggactctggc catcatgttg acagccttgc acttccacag gctacaagcc ctgggaccat
13261 ctttctgcct taagggcagg agcccacttc tgtggcacca gattccaccc tgggaactgt
13321 ggaaaaagta ggagaggcag attccctcag tgtcttcctc ttaaacctca atcatcgaga
13381 cattaggggg tattttctgt tcacatttat ctttttcaag ccacatcttc ctctaacaaa
13441 tctctcagta tgcgattggt ctcaagctaa aacaaaaata aatgtcagtt tatattttac
13501 acatccacaa agcagtggct tggggttttt tttttttttt ttatcttgtt gatcaagtga
13561 cacccaggac atgtaaatat ttcataagcc ttaaacattt cctgaggtaa gaaacaagct
13621 ctcaaagcaa aagctcaatt agaaatggcc cttgtgggga accttcccat tctggtcgac
13681 cagaactcta gccagatgaa atggcaatgc tagcgccacc agcaacgtca gaaacgtaga
13741 ccttaaagcg gttttaaaaa tagaaaagaa gcgttcctca catctgccag taatggaatt
13801 ttctgtcagt aaatggaatg tgtaggcagg acctggaata actggagaga gtgcaacgct
13861 tcggggtgaa gggcgggtgg ggactggaaa tgttgagacg ggggcagcca tgggaaggta
13921 tgagtaatag aattctttct gtacgacaca gctcatccag ggattccagg ggaccttaat
13981 aaatcacggt agctttgggc aagagttggg cacgtcgccc gactgtgcag gatggattga
14041 tgctggtatt aatttggtct ggagccctat agaggatctc gttgctttga
//