LOCUS AF018253 3136 bp mRNA linear HUM 22-NOV-1997
DEFINITION Homo sapiens receptor activator of nuclear factor-kappa B (RANK)
mRNA, complete cds.
ACCESSION AF018253
VERSION AF018253.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3136)
AUTHORS Anderson,D.M., Maraskovsky,E., Billingsley,W.L., Dougall,W.C.,
Tometsko,M.E., Roux,E.R., Teepe,M.C., DuBose,R.F., Cosman,D. and
Galibert,L.
TITLE A homologue of the TNF receptor and its ligand enhance T-cell
growth and dendritic-cell function
JOURNAL Nature 390 (6656), 175-179 (1997)
PUBMED 9367155
REFERENCE 2 (bases 1 to 3136)
AUTHORS Anderson,D.M., Billingsley,W., Dougall,W., Maraskovsky,E.,
Cosman,D., DuBose,R. and Galibert,L.
TITLE Direct Submission
JOURNAL Submitted (11-AUG-1997) Molecular Biology, Immunex Corp., 51
University St., Seattle, WA 98101, USA
FEATURES Location/Qualifiers
source 1..3136
/db_xref="H-InvDB:HIT000062462"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18q22.1"
gene 1..3136
/gene="RANK"
CDS 39..1889
/gene="RANK"
/codon_start=1
/product="receptor activator of nuclear factor-kappa B"
/protein_id="AAB86809.1"
/translation="MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLG
RCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVV
AGNSTTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFS
DAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILL
LFASVALVAAIIFGVCYRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANF
GQQGACEGVLLLTLEEKTFPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTE
IEEDSFRQMPTEDEYMDRPSQPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTG
TQSTVGSESCNCTEPLCRTDWTPMSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCR
NPPGEDCEPLVGSPKRGPLPQCAYGMGLPPEEEASRTEARDQPEDGADGRLPSSARAG
AGSGSSPGGQSPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEGAAAAAEPM
GRPVQEETLARRDSFAGNGPRFPDPCGGPEGLREPEKASRPVQEQGGAKA"
BASE COUNT 696 a 879 c 859 g 702 t
ORIGIN
1 ccgctgaggc cgcggcgccc gccagcctgt cccgcgccat ggccccgcgc gcccggcggc
61 gccgcccgct gttcgcgctg ctgctgctct gcgcgctgct cgcccggctg caggtggctt
121 tgcagatcgc tcctccatgt accagtgaga agcattatga gcatctggga cggtgctgta
181 acaaatgtga accaggaaag tacatgtctt ctaaatgcac tactacctct gacagtgtat
241 gtctgccctg tggcccggat gaatacttgg atagctggaa tgaagaagat aaatgcttgc
301 tgcataaagt ttgtgataca ggcaaggccc tggtggccgt ggtcgccggc aacagcacga
361 ccccccggcg ctgcgcgtgc acggctgggt accactggag ccaggactgc gagtgctgcc
421 gccgcaacac cgagtgcgcg ccgggcctgg gcgcccagca cccgttgcag ctcaacaagg
481 acacagtgtg caaaccttgc cttgcaggct acttctctga tgccttttcc tccacggaca
541 aatgcagacc ctggaccaac tgtaccttcc ttggaaagag agtagaacat catgggacag
601 agaaatccga tgcggtttgc agttcttctc tgccagctag aaaaccacca aatgaacccc
661 atgtttactt gcccggttta ataattctgc ttctcttcgc gtctgtggcc ctggtggctg
721 ccatcatctt tggcgtttgc tataggaaaa aagggaaagc actcacagct aatttgtggc
781 actggatcaa tgaggcttgt ggccgcctaa gtggagataa ggagtcctca ggtgacagtt
841 gtgtcagtac acacacggca aactttggtc agcagggagc atgtgaaggt gtcttactgc
901 tgactctgga ggagaagaca tttccagaag atatgtgcta cccagatcaa ggtggtgtct
961 gtcagggcac gtgtgtagga ggtggtccct acgcacaagg cgaagatgcc aggatgctct
1021 cattggtcag caagaccgag atagaggaag acagcttcag acagatgccc acagaagatg
1081 aatacatgga caggccctcc cagcccacag accagttact gttcctcact gagcctggaa
1141 gcaaatccac acctcctttc tctgaacccc tggaggtggg ggagaatgac agtttaagcc
1201 agtgcttcac ggggacacag agcacagtgg gttcagaaag ctgcaactgc actgagcccc
1261 tgtgcaggac tgattggact cccatgtcct ctgaaaacta cttgcaaaaa gaggtggaca
1321 gtggccattg cccgcactgg gcagccagcc ccagccccaa ctgggcagat gtctgcacag
1381 gctgccggaa ccctcctggg gaggactgtg aacccctcgt gggttcccca aaacgtggac
1441 ccttgcccca gtgcgcctat ggcatgggcc ttccccctga agaagaagcc agcaggacgg
1501 aggccagaga ccagcccgag gatggggctg atgggaggct cccaagctca gcgagggcag
1561 gtgccgggtc tggaagctcc cctggtggcc agtcccctgc atctggaaat gtgactggaa
1621 acagtaactc cacgttcatc tccagcgggc aggtgatgaa cttcaagggc gacatcatcg
1681 tggtctacgt cagccagacc tcgcaggagg gcgcggcggc ggctgcggag cccatgggcc
1741 gcccggtgca ggaggagacc ctggcgcgcc gagactcctt cgcggggaac ggcccgcgct
1801 tcccggaccc gtgcggcggc cccgaggggc tgcgggagcc ggagaaggcc tcgaggccgg
1861 tgcaggagca aggcggggcc aaggcttgag cgccccccat ggctgggagc ccgaagctcg
1921 gagccagggc tcgcgagggc agcaccgcag cctctgcccc agccccggcc acccagggat
1981 cgatcggtac agtcgaggaa gaccacccgg cattctctgc ccactttgcc ttccaggaaa
2041 tgggcttttc aggaagtgaa ttgatgagga ctgtccccat gcccacggat gctcagcagc
2101 ccgccgcact ggggcagatg tctcccctgc cactcctcaa actcgcagca gtaatttgtg
2161 gcactatgac agctattttt atgactatcc tgttctgtgg ggggggggtc tatgttttcc
2221 ccccatattt gtattccttt tcataacttt tcttgatatc tttcctccct cttttttaat
2281 gtaaaggttt tctcaaaaat tctcctaaag gtgagggtct ctttcttttc tcttttcctt
2341 ttttttttct ttttttggca acctggctct ggcccaggct agagtgcagt ggtgcgatta
2401 tagcccggtg cagcctctaa ctcctgggct caagcaatcc aagtgatcct cccacctcaa
2461 ccttcggagt agctgggatc acagctgcag gccacgccca gcttcctccc cccgactccc
2521 cccccccaga gacacggtcc caccatgtta cccagcctgg tctcaaactc cccagctaaa
2581 gcagtcctcc agcctcggcc tcccaaagta ctgggattac aggcgtgagc ccccacgctg
2641 gcctgcttta cgtattttct tttgtgcccc tgctcacagt gttttagaga tggctttccc
2701 agtgtgtgtt cattgtaaac acttttggga aagggctaaa catgtgaggc ctggagatag
2761 ttgctaagtt gctaggaaca tgtggtggga ctttcatatt ctgaaaaatg ttctatattc
2821 tcatttttct aaaagaaaga aaaaaggaaa cccgatttat ttctcctgaa tctttttaag
2881 tttgtgtcgt tccttaagca gaactaagct cagtatgtga ccttacccgc taggtggtta
2941 atttatccat gctggcagag gcactcaggt acttggtaag caaatttcta aaactccaag
3001 ttgctgcagc ttggcattct tcttattcta gaggtctctc tggaaaagat ggagaaaatg
3061 aacaggacat ggggctcctg gaaagaaagg gcccgggaag ttcaaggaag aataaagttg
3121 aaattttaaa aaaaaa
//