LOCUS AF017790 2150 bp mRNA linear HUM 09-OCT-1997
DEFINITION Homo sapiens retinoblastoma-associated protein HEC mRNA, complete
cds.
ACCESSION AF017790
VERSION AF017790.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2150)
AUTHORS Chen,Y., Riley,D.J., Chen,P.L. and Lee,W.H.
TITLE HEC, a novel nuclear protein rich in leucine heptad repeats
specifically involved in mitosis
JOURNAL Mol. Cell. Biol. 17 (10), 6049-6056 (1997)
PUBMED 9315664
REFERENCE 2 (bases 1 to 2150)
AUTHORS Chen,Y. and Lee,W.-H.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-1997) Molecular Medicine, UTHSCSA, Inst.
Biotechnology, 15355 Lambda Drive, San Antonio, TX 78245, USA
FEATURES Location/Qualifiers
source 1..2150
/db_xref="H-InvDB:HIT000062445"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2150
/gene="HEC"
CDS 105..2033
/gene="HEC"
/note="nuclear protein"
/codon_start=1
/product="retinoblastoma-associated protein HEC"
/protein_id="AAB80726.1"
/translation="MKRSSVSSGGAGRLSMQELRSQDVNKQGLYTPQTKEKPTFGKLS
INKPTSERKVSLFGKRTSGHGSRNSQLGIFSSSEKIKDPRPLNDKAFIQQCIRQLCEF
LTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGY
PFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAMKESSPLFDDGQPWGEETEDG
IMHNKLFLDYTIKCYESFMSGADSFDEMNAELQSKLKDLFNVDAFKLESLEAKNRALN
EQIARLEQEREKEPNRLESLRKLKASLQGDVQKYQAYMSNLESHSAILDQKLNGLNEE
IARVELECETIKQENTRLQNIIDNQKYSVADIERINHERNELQQTINKLTKDLEAEQQ
KLWNEELKYARGKEAIETQLAEYHKLARKLKLIPKGAENSKGYDFEIKFNPEAGANCL
VKYRAQVYVPLKELLNETEEEINKALNKKMGLEDTLEQLNAMITESKRSVRTLKEEVQ
KLDDLYQQKIKEAEEEDEKCASELESLEKHKHLLESTVNQGLSEAMNELDAVQREYQL
VVQTTTEERRKVGNNLQRLLEMVATHVGSVEKHLEEQIAKVDREYEECMSEDLSENIK
EIRDKYEKKATLIKSSEE"
BASE COUNT 810 a 362 c 464 g 514 t
ORIGIN
1 ctcgagccac gaaggccccg ctgtcctgtc tagcagatac ttgcacggtt tacagaaatt
61 cggtccctgg gtcgtgtcag gaaactggaa aaaaggtcat aagcatgaag cgcagttcag
121 tttccagcgg tggtgctggc cgcctctcca tgcaggagtt aagatcccag gatgtaaata
181 aacaaggcct ctatacccct caaaccaaag agaaaccaac ctttggaaag ttgagtataa
241 acaaaccgac atctgaaaga aaagtctcgc tatttggcaa aagaactagt ggacatggat
301 cccggaatag tcaacttggt atattttcca gttctgagaa aatcaaggac ccgagaccac
361 ttaatgacaa agcattcatt cagcagtgta ttcgacaact ctgtgagttt cttacagaaa
421 atggttatgc acataatgtg tccatgaaat ctctacaagc tccctctgtt aaagacttcc
481 tgaagatctt cacatttctt tatggcttcc tgtgcccctc atacgaactt cctgacacaa
541 agtttgaaga agaggttcca agaatcttta aagaccttgg gtatcctttt gcactatcca
601 aaagctccat gtacacagtg ggggctcctc atacatggcc tcacattgtg gcagccttag
661 tttggctaat agactgcatc aagatacata ctgccatgaa agaaagctca cctttatttg
721 atgatgggca gccttgggga gaagaaactg aagatggaat tatgcataat aagttgtttt
781 tggactacac cataaaatgc tatgagagtt ttatgagtgg tgccgacagc tttgatgaga
841 tgaatgcaga gctgcagtca aaactgaagg atttatttaa tgtggatgct tttaagctgg
901 aatcattaga agcaaaaaac agagcattga atgaacagat tgcaagattg gaacaagaaa
961 gagaaaaaga accgaatcgt ctagagtcgt tgagaaaact gaaggcttcc ttacaaggag
1021 atgttcaaaa gtatcaggca tacatgagca atttggagtc tcattcagcc attcttgacc
1081 agaaattaaa tggtctcaat gaggaaattg ctagagtaga actagaatgt gaaacaataa
1141 aacaggagaa cactcgacta cagaatatca ttgacaacca gaagtactca gttgcagaca
1201 ttgagcgaat aaatcatgaa agaaatgaat tgcagcagac tattaataaa ttaaccaagg
1261 acctggaagc tgaacaacag aagttgtgga atgaggagtt aaaatatgcc agaggcaaag
1321 aagcgattga aacacaatta gcagagtatc acaaattggc tagaaaatta aaacttattc
1381 ctaaaggtgc tgagaattcc aaaggttatg actttgaaat taagtttaat cccgaggctg
1441 gtgccaactg ccttgtcaaa tacagggctc aagtttatgt acctcttaag gaactcctga
1501 atgaaactga agaagaaatt aataaagccc taaataaaaa aatgggtttg gaggatactt
1561 tagaacaatt gaatgcaatg ataacagaaa gcaagagaag tgtgagaact ctgaaagaag
1621 aagttcaaaa gctggatgat ctttaccaac aaaaaattaa ggaagcagag gaagaggatg
1681 aaaaatgtgc cagtgagctt gagtccttgg agaaacacaa gcacctgcta gaaagtactg
1741 ttaaccaggg gctcagtgaa gctatgaatg aattagatgc tgttcagcgg gaataccaac
1801 tagttgtgca aaccacgact gaagaaagac gaaaagtggg aaataacttg caacgtctgt
1861 tagagatggt tgctacacat gttgggtctg tagagaaaca tcttgaggag cagattgcta
1921 aagttgatag agaatatgaa gaatgcatgt cagaagatct ctcggaaaat attaaagaga
1981 ttagagataa gtatgagaag aaagctactc taattaagtc ttctgaagaa tgaagataaa
2041 atgttgatca tgtatatata tccatagtga ataaaattgt ctcagtaaaa aaaaaaaaaa
2101 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//