LOCUS AF017146 2784 bp mRNA linear HUM 05-JAN-1999
DEFINITION Homo sapiens DNA topoisomerase III beta (TOP3b) mRNA, complete cds.
ACCESSION AF017146
VERSION AF017146.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2784)
AUTHORS Kawasaki,K., Minoshima,S., Nakato,E., Shibuya,K., Shintani,A.,
Schmeits,J.L., Wang,J. and Shimizu,N.
TITLE One-megabase sequence analysis of the human immunoglobulin lambda
gene locus
JOURNAL Genome Res. 7 (3), 250-261 (1997)
PUBMED 9074928
REFERENCE 2 (bases 1 to 2784)
AUTHORS Hanai,R., Li,W. and Wang,J.C.
TITLE Direct Submission
JOURNAL Submitted (05-AUG-1997) Dept. Chemistry, Rikkyo University, 3-34-1
Nishi-Ikebukuro, Toshima, Tokyo 171, Japan
COMMENT Kawasaki, K. Genome Res. 7, 250-261, 1997.
FEATURES Location/Qualifiers
source 1..2784
/db_xref="H-InvDB:HIT000062415"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="22"
/map="22q11"
gene 1..2784
/gene="TOP3b"
CDS 114..2702
/gene="TOP3b"
/codon_start=1
/product="DNA topoisomerase III beta"
/protein_id="AAD01614.1"
/translation="MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGT
FAGQPVRFKMTSVCGHVMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFL
QVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDI
CNAMACLGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQ
TPTLGFCVERHDKIQSFKPETYWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNM
TKLEKEAQVEATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYI
SYPRTETTHYPENFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITP
MKSATEAELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSP
GFTEVMPWQSVPLEESLPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAELITLMEKHGI
GTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTIRSAVEK
QLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRC
GKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKLYKELRCPLDDFELVLWSSGSRG
KSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSMLGIGQCVECESGVLVLDPTS
GPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLDVDFNKAKSPLPGDETQHM
GCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARRPPGKPNPRRPKDKMSA
LAAYFV"
variation 2447..2448
/gene="TOP3b"
/replace="c"
BASE COUNT 629 a 829 c 806 g 520 t
ORIGIN
1 gcggtgcggc tgtgggagtc agcattggta atagtgctgt gctgcggaag agtggagtct
61 aaactttttc attgccagtg ccccgaaact ggagtgtgaa ggaccgagac aagatgaaga
121 ctgtgctcat ggttgctgaa aagccgtcct tggcacagtc aattgccaaa atcctctcta
181 gagggagcct gtcctcacac aaagggctga acggggcctg ctcagtccac gagtacactg
241 ggacctttgc tggccagcca gtgcgcttca agatgacgtc tgtctgtggt cacgtgatga
301 ccctggattt cctgggaaaa tacaacaaat gggacaaagt ggaccccgca gaactgttca
361 gccaagctcc cacggagaag aaagaagcta accccaagct gaacatggtg aagttcctgc
421 aggtggaggg cagaggctgc gactacatcg tgctgtggct ggactgcgac aaggaggggg
481 agaacatctg ctttgaggtt cttgatgctg ttctgcccgt catgaacaag gcccatggtg
541 gcgagaagac cgtgttccgg gccaggttta gctccatcac ggacacagac atctgtaatg
601 ccatggcctg cctaggcgag cctgaccaca acgaggcgct ctcagtggat gctcgccagg
661 agctggacct gcgaatcggc tgtgcattca ccaggtttca gactaaatat ttccagggga
721 aatacggtga tttagacagc tctctcatct cctttgggcc gtgtcagact ccaaccctgg
781 gattctgtgt ggagagacat gataaaatcc agtccttcaa accagagacc tactgggtgc
841 tgcaggccaa ggttaacact gacaaagaca gatctctcct tttggactgg gaccgagtaa
901 gagtgtttga ccgggagatc gcacagatgt ttttaaacat gacaaagctg gagaaggaag
961 cccaggtgga ggccacaagc aggaaagaaa aggccaagca gaggcccctg gccctgaaca
1021 ctgtggagat gctgcgtgtg gccagctctt ctctgggcat ggggccgcag cacgccatgc
1081 agacggctga gcggctctac acgcaaggct acatcagcta cccacggaca gagaccaccc
1141 actaccctga gaactttgac ctgaagggct ctctgcggca gcaggccaac cacccctact
1201 gggccgacac ggtgaagcgg ttgttagcag aaggtatcaa ccgcccgcgg aaaggccatg
1261 acgccggcga ccatcccccc atcaccccca tgaagtctgc cacagaggcc gaattagggg
1321 gtgacgcgtg gcggctctat gagtacatca ccagacactt catcgccacg gtcagccatg
1381 actgcaagta cctgcagagc accatctcct tcagaattgg gcccgagctc ttcacctgct
1441 ccgggaagac cgtcctctca ccaggcttca cggaggtcat gccctggcag agcgtgcccc
1501 tggaggagag cctgcccact tgccagcggg gtgatgcctt ccctgtgggc gaggtgaaga
1561 tgctggagaa gcagacgaac ccacccgact acctgacgga ggccgagctc atcacgctca
1621 tggagaagca tggcatcggc acggatgcca gcatccctgt gcatatcaac aacatctgcc
1681 agcgcaacta tgtcacggtg gagagcgggc gccggctcaa gcccaccaac ctcggcatcg
1741 tcctggtgca cggctactat aagattgatg cagagctggt gctccccacc atccgcagtg
1801 cagtggagaa gcagctgaac ctgatcgccc agggcaaggc cgactaccgc caggtcctgg
1861 gccacaccct ggacgtgttc aagaggaagt tccactactt tgtcgactcc attgctggca
1921 tggatgagtt gatggaggtg tctttctcgc ccctggcggc cacaggcaag cccctctcac
1981 gctgtgggaa gtgccaccgc ttcatgaagt acatccaggc caagccaagc cgcctgcact
2041 gctcccactg cgatgagacc tacacgctcc cccagaacgg caccatcaag ctctacaagg
2101 agctccgctg ccctctggat gacttcgagc tggtcctgtg gtcatcaggc tctcggggca
2161 agagctaccc gctgtgcccc tactgctaca accacccacc cttccgagac atgaagaaag
2221 gcatgggctg caacgagtgt acgcacccct cctgccagca ctcgctgagc atgctgggca
2281 tcggccagtg cgtggaatgt gagagcgggg tgctggtgct ggaccccacc tcgggcccca
2341 agtggaaggt ggcctgcaac aagtgcaacg tggtagcgca ctgcttcgag aacgcccacc
2401 gcgtgcgggt gtccgccgac acctgcagtg tctgtgaggc cgccttgctt gatgtggact
2461 tcaacaaggc caagtcccca ctcccgggcg atgagacgca gcacatgggc tgcgtctttt
2521 gtgaccccgt cttccaggag ctggtggagc tgaagcatgc ggcctcctgc caccccatgc
2581 accgcggtgg accagggaga aggcagggtc gagggcgggg ccgggccagg aggccccctg
2641 ggaagcccaa ccccagacgg cccaaggaca agatgtcagc cctggccgcc tactttgtat
2701 gatgaccctg tcctccctca cccaggctgc agtgccatgc agacacctca tggcacttca
2761 aactattaaa atgcatttta tctt
//