LOCUS AF016098 2796 bp mRNA linear HUM 09-APR-1998
DEFINITION Homo sapiens vascular endothelial cell growth factor 165 receptor 2
(VEGF165R2) mRNA, complete cds.
ACCESSION AF016098
VERSION AF016098.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2796)
AUTHORS Soker,S., Takashima,S., Miao,H.Q., Neufeld,G. and Klagsbrun,M.
TITLE Neuropilin-1 is expressed by endothelial and tumor cells as an
isoform-specific receptor for vascular endothelial growth factor
JOURNAL Cell 92 (6), 735-745 (1998)
PUBMED 9529250
REFERENCE 2 (bases 1 to 2796)
AUTHORS Takashima,S., Soker,S. and Klagsbrun,M.
TITLE Direct Submission
JOURNAL Submitted (25-JUL-1997) Surgical Research, Children's Hospital, 320
Longwood Ave., Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..2796
/db_xref="H-InvDB:HIT000062383"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="MDA-MB-231"
/cell_type="adenocarcinoma"
/tissue_type="breast"
gene 1..2796
/gene="VEGF165R2"
CDS 1..2796
/gene="VEGF165R2"
/codon_start=1
/product="vascular endothelial cell growth factor 165
receptor 2"
/protein_id="AAC12922.1"
/translation="MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPG
YPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLG
KHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTI
ESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDG
IPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQ
CNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLR
FLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATE
VVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADSQI
SASSTQEYLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGARG
GDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRRFDPI
PAQYVRVYPERWSPAGIGMRLEVLGCDWTDSKPTVETLGPTVKSEETTTPYPTEEEAT
ECGENCSFEDDKDLQLPSGFNCNFDFLEEPCGWMYDHAKWLRTTWASSSSPNDRTFPD
DRNFLRLQSDSQREGQYARLISPPVHLPRSPVCMEFQYQATGGRGVALQVVREASQES
KLLWVIREDQGGEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRISTDVPLE
NCMEPISAFAGENFKVDIPEIHEREGYEDEIDDEYEVDWSNSSSATSGSGAPSTDKEK
SWLYTLDPILITIIAMSSLGVLLGATCAGLLLYCTCSYSGLSSRSCTTLENYNFELYD
GLKHKVKMNHQKCCSEA"
BASE COUNT 669 a 810 c 754 g 563 t
ORIGIN
1 atggatatgt ttcctctcac ctgggttttc ttagccctct acttttcaag acaccaagtg
61 agaggccaac cagacccacc gtgcggaggt cgtttgaatt ccaaagatgc tggctatatc
121 acctctcccg gttaccccca ggactacccc tcccaccaga actgcgagtg gattgtttac
181 gcccccgaac ccaaccagaa gattgtcctc aacttcaacc ctcactttga aatcgagaag
241 cacgactgca agtatgactt tatcgagatt cgggatgggg acagtgaatc cgcagacctc
301 ctgggcaaac actgtgggaa catcgccccg cccaccatca tctcctcggg ctccatgctc
361 tacatcaagt tcacctccga ctacgcccgg cagggggcag gcttctctct gcgctacgag
421 atcttcaaga caggctctga agattgctca aaaaacttca caagccccaa cgggaccatc
481 gaatctcctg ggtttcctga gaagtatcca cacaacttgg actgcacctt taccatcctg
541 gccaaaccca agatggagat catcctgcag ttcctgatct ttgacctgga gcatgaccct
601 ttgcaggtgg gagaggggga ctgcaagtac gattggctgg acatctggga tggcattcca
661 catgttggcc ccctgattgg caagtactgt gggaccaaaa caccctctga acttcgttca
721 tcgacgggga tcctctccct gacctttcac acggacatgg cggtggccaa ggatggcttc
781 tctgcgcgtt actacctggt ccaccaagag ccactagaga actttcagtg caatgttcct
841 ctgggcatgg agtctggccg gattgctaat gaacagatca gtgcctcatc tacctactct
901 gatgggaggt ggacccctca acaaagccgg ctccatggtg atgacaatgg ctggaccccc
961 aacttggatt ccaacaagga gtatctccag gtggacctgc gctttttaac catgctcacg
1021 gccatcgcaa cacagggagc gatttccagg gaaacacaga atggctacta cgtcaaatcc
1081 tacaagctgg aagtcagcac taatggagag gactggatgg tgtaccggca tggcaaaaac
1141 cacaaggtat ttcaagccaa caacgatgca actgaggtgg ttctgaacaa gctccacgct
1201 ccactgctga caaggtttgt tagaatccgc cctcagacct ggcactcagg tatcgccctc
1261 cggctggagc tcttcggctg ccgggtcaca gatgctccct gctccaacat gctggggatg
1321 ctctcaggcc tcattgcaga ctcccagatc tccgcctctt ccacccagga atacctctgg
1381 agccccagtg cagcccgcct ggtcagcagc cgctcgggct ggttccctcg aatccctcag
1441 gcccagcccg gtgaggagtg gcttcaggta gatctgggaa cacccaagac agtgaaaggt
1501 gtcatcatcc agggagcccg cggaggagac agtatcactg ctgtggaagc cagagcattt
1561 gtgcgcaagt tcaaagtctc ctacagccta aacggcaagg actgggaata cattcaggac
1621 cccaggaccc agcagccaaa gctgttcgaa gggaacatgc actatgacac ccctgacatc
1681 cgaaggtttg accccattcc ggcacagtat gtgcgggtat acccggagag gtggtcgccg
1741 gcggggattg ggatgcggct ggaggtgctg ggctgtgact ggacagactc caagcccacg
1801 gtagagacgc tgggacccac tgtgaagagc gaagagacaa ccacccccta ccccaccgaa
1861 gaggaggcca cagagtgtgg ggagaactgc agctttgagg atgacaaaga tttgcagctc
1921 ccttcgggat tcaattgcaa cttcgatttc ctcgaggagc cctgtggttg gatgtatgac
1981 catgccaagt ggctccggac cacctgggcc agcagctcca gcccaaacga ccggacgttt
2041 ccagatgaca ggaatttctt gcggctgcag agtgacagcc agagagaggg ccagtatgcc
2101 cggctcatca gcccccctgt ccacctgccc cgaagcccgg tgtgcatgga gttccagtac
2161 caggccacgg gcggccgcgg ggtggcgctg caggtggtgc gggaagccag ccaggagagc
2221 aagttgctgt gggtcatccg tgaggaccag ggcggcgagt ggaagcacgg gcggatcatc
2281 ctgcccagct acgacatgga gtaccagatt gtgttcgagg gagtgatagg gaaaggacgt
2341 tccggagaga ttgccattga tgacattcgg ataagcactg atgtcccact ggagaactgc
2401 atggaaccca tctcggcttt tgcaggtgag aattttaaag tggacatccc agaaatacat
2461 gagagagaag gatatgaaga tgaaattgat gatgaatacg aggtggactg gagcaattct
2521 tcttctgcaa cctcagggtc tggcgccccc tcgaccgaca aagaaaagag ctggctgtac
2581 accctggacc ccatcctcat caccatcatc gccatgagct cactgggcgt cctcctgggg
2641 gccacctgtg caggcctcct gctctactgc acctgttcct actcgggcct gagctcccga
2701 agctgcacca cactggagaa ctacaacttc gagctctacg atggccttaa gcacaaggtc
2761 aagatgaacc accaaaagtg ctgctccgag gcatga
//