LOCUS AF016031 4668 bp mRNA linear HUM 05-NOV-1997
DEFINITION Homo sapiens thyroid hormone receptor activator molecule (TRAM-1)
mRNA, complete cds.
ACCESSION AF016031
VERSION AF016031.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4668)
AUTHORS Takeshita,A., Cardona,G.R., Koibuchi,N., Suen,C.S. and Chin,W.W.
TITLE TRAM-1, A novel 160-kDa thyroid hormone receptor activator
molecule, exhibits distinct properties from steroid receptor
coactivator-1
JOURNAL J. Biol. Chem. 272 (44), 27629-27634 (1997)
PUBMED 9346901
REFERENCE 2 (bases 1 to 4668)
AUTHORS Takeshita,A., Cardona,G.R., Koibuchi,N. and Chin,W.W.
TITLE Direct Submission
JOURNAL Submitted (24-JUL-1997) Medicine, Brigham and Women's Hospital,
Harvard Medical School, 20 Shattuck Street #905, Boston, MA 02115,
USA
FEATURES Location/Qualifiers
source 1..4668
/db_xref="H-InvDB:HIT000062379"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..4668
/gene="TRAM-1"
CDS 192..4466
/gene="TRAM-1"
/note="nuclear hormone receptor coactivator protein"
/codon_start=1
/product="thyroid hormone receptor activator molecule"
/protein_id="AAC51849.1"
/translation="MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKY
IEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSS
TGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNI
LHEEDRKDFLKNLPKSTVNGVSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMR
QRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITRHDLSGK
VVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYR
FSLADGTIVTAQTKSKLFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMA
GCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQS
PSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMA
SSGNTGNHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMNITQPSKVSNQD
SKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKKLLQL
LTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKH
RILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGNVVKQEQLSPKKKENNALLRY
LLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLD
NLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAV
SLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGSSMGGPNRNVTVTQT
PSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGAR
PVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLL
RNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQAL
EPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQG
NFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAA
VMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQ
QQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQ
PDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQ
QQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC"
BASE COUNT 1389 a 1089 c 1100 g 1090 t
ORIGIN
1 ctgcggctta gtcggtggcg gccggcggcg gctgcgggct gagcggcgag tttccgattt
61 aaagctgagc tgcgaggaaa atggcggcgg gaggatcaaa atacttgctg gatggtggac
121 tcagagacca ataaaaataa actgcttgaa tatcctttga ctggttagcc agttgctgat
181 gtatattcaa gatgagtgga ttaggagaaa acttggatcc actggccagt gattcacgaa
241 aacgcaaatt gccatgtgat actccaggac aaggtcttac ctgcagtggt gaaaaacgga
301 gacgggagca ggaaagtaaa tatattgaag aattggctga gctgatatct gccaatctta
361 gtgatattga caatttcaat gtcaaaccag ataaatgtgc gattttaaag gaaacagtaa
421 gacagatacg tcaaataaaa gagcaaggaa aaactatttc caatgatgat gatgttcaaa
481 aagccgatgt atcttctaca gggcagggag ttattgataa agactcctta ggaccgcttt
541 tacttcaggc attggatggt ttcctatttg tggtgaatcg agacggaaac attgtatttg
601 tatcagaaaa tgtcacacaa tacctgcaat ataagcaaga ggacctggtt aacacaagtg
661 tttacaatat cttacatgaa gaagacagaa aggattttct taagaattta ccaaaatcta
721 cagttaatgg agtttcctgg acaaatgaga cccaaagaca aaaaagccat acatttaatt
781 gccgtatgtt gatgaaaaca ccacatgata ttctggaaga cataaacgcc agtcctgaaa
841 tgcgccagag atatgaaaca atgcagtgct ttgccctgtc tcagccacga gctatgatgg
901 aggaagggga agatttgcaa tcttgtatga tctgtgtggc acgccgcatt actacaggag
961 aaagaacatt tccatcaaac cctgagagct ttattaccag acatgatctt tcaggaaagg
1021 ttgtcaatat agatacaaat tcactgagat cctccatgag gcctggcttt gaagatataa
1081 tccgaaggtg tattcagaga ttttttagtc taaatgatgg gcagtcatgg tcccagaaac
1141 gtcactatca agaagcttat cttaatggcc atgcagaaac cccagtatat cgattctcgt
1201 tggctgatgg aactatagtg actgcacaga caaaaagcaa actcttccga aatcctgtaa
1261 caaatgatcg acatggcttt gtctcaaccc acttccttca gagagaacag aatggatata
1321 gaccaaaccc aaatcctgtt ggacaaggga ttagaccacc tatggctgga tgcaacagtt
1381 cggtaggcgg catgagtatg tcgccaaacc aaggcttaca gatgccgagc agcagggctt
1441 atggcttggc agaccctagc accacagggc agatgagtgg agctaggtat gggggttcca
1501 gtaacatagc ttcattgacc cctgggccag gcatgcaatc accatcttcc taccagaaca
1561 acaactatgg gctcaacatg agtagccccc cacatgggag tcctggtctt gccccaaacc
1621 agcagaatat catgatttct cctcgtaatc gtgggagtcc aaagatagcc tcacatcagt
1681 tttctcctgt tgcaggtgtg cactctccca tggcatcttc tggcaatact gggaaccaca
1741 gcttttccag cagctctctc agtgccctgc aagccatcag tgaaggtgtg gggacttccc
1801 ttttatctac tctgtcatca ccaggcccca aattggataa ctctcccaat atgaatatta
1861 cccaaccaag taaagtaagc aatcaggatt ccaagagtcc tctgggcttt tattgcgacc
1921 aaaatccagt ggagagttca atgtgtcagt caaatagcag agatcacctc agtgacaaag
1981 aaagtaagga gagcagtgtt gagggggcag agaatcaaag gggtcctttg gaaagcaaag
2041 gtcataaaaa attactgcag ttacttacct gttcttctga tgaccggggt cattcctcct
2101 tgaccaactc ccccctagat tcaagttgta aagaatcttc tgttagtgtc accagcccct
2161 ctggagtctc ctcctctaca tctggaggag tatcctctac atccaatatg catgggtcac
2221 tgttacaaga gaagcaccgg attttgcaca agttgctgca gaatgggaat tcaccagctg
2281 aggtagccaa gattactgca gaagccactg ggaaagacac cagcagtata acttcttgtg
2341 gggacggaaa tgttgtcaag caggagcagc taagtcctaa gaagaaggag aataatgcac
2401 ttcttagata cctgctggac agggatgatc ctagtgatgc actctctaaa gaactacagc
2461 cccaagtgga aggagtggat aataaaatga gtcagtgcac cagctccacc attcctagct
2521 caagtcaaga gaaagaccct aaaattaaga cagagacaag tgaagaggga tctggagact
2581 tggataatct agatgctatt cttggtgatc tgactagttc tgacttttac aataattcca
2641 tatcctcaaa tggtagtcat ctggggacta agcaacaggt gtttcaagga actaattctc
2701 tgggtttgaa aagttcacag tctgtgcagt ctattcgtcc tccatataac cgagcagtgt
2761 ctctggatag ccctgtttct gttggctcaa gtcctccagt aaaaaatatc agtgctttcc
2821 ccatgttacc aaagcaaccc atgttgggtg ggaatccaag aatgatggat agtcaggaaa
2881 attatggctc aagtatgggt gggccaaacc gaaatgtgac tgtgactcag actccttcct
2941 caggagactg gggcttacca aactcaaagg ccggcagaat ggaacctatg aattcaaact
3001 ccatgggaag accaggagga gattataata cttctttacc cagacctgca ctgggtggct
3061 ctattcccac attgcctctt cggtctaata gcataccagg tgcgagacca gtattgcaac
3121 agcagcagca gatgcttcaa atgaggcctg gtgaaatccc catgggaatg ggggctaatc
3181 cctatggcca agcagcagca tctaaccaac tgggttcctg gcccgatggc atgttgtcca
3241 tggaacaagt ttctcatggc actcaaaata ggcctcttct taggaattcc ctggatgatc
3301 ttgttgggcc accttccaac ctggaaggcc agagtgacga aagagcatta ttggaccagc
3361 tgcacactct tctcagcaac acagatgcca caggcctgga agaaattgac agagctttgg
3421 gcattcctga acttgtcaat cagggacagg cattagagcc caaacaggat gctttccaag
3481 gccaagaagc agcagtaatg atggatcaga aggcaggatt atatggacag acatacccag
3541 cacaggggcc tccaatgcaa ggaggctttc atcttcaggg acaatcacca tcttttaact
3601 ctatgatgaa tcagatgaac cagcaaggca attttcctct ccaaggaatg cacccacgag
3661 ccaacatcat gagaccccgg acaaacaccc ccaagcaact tagaatgcag cttcagcaga
3721 ggctgcaggg ccagcagttt ttgaatcaga gccgacaggc acttgaattg aaaatggaaa
3781 accctactgc tggtggtgct gcggtgatga ggcctatgat gcagccccag gtgagctccc
3841 agcagggttt tcttaatgct caaatggtcg cccaacgcag cagagagctg ctaagtcatc
3901 acttccgaca acagagggtg gctatgatga tgcagcagca gcagcagcag caacagcagc
3961 agcagcagca gcagcagcag caacagcaac agcaacagca acagcagcaa cagcagcaaa
4021 cccaggcctt cagcccacct cctaatgtga ctgcttcccc cagcatggat gggcttttgg
4081 caggacccac aatgccacaa gctcctccgc aacagtttcc atatcaacca aattatggaa
4141 tgggacaaca accagatcca gcctttggtc gagtgtctag tcctcccaat gcaatgatgt
4201 cgtcaagaat gggtccctcc cagaatccca tgatgcaaca cccgcaggct gcatccatct
4261 atcagtcctc agaaatgaag ggctggccat caggaaattt ggccaggaac agctcctttt
4321 cccagcagca gtttgcccac caggggaatc ctgcagtgta tagtatggtg cacatgaatg
4381 gcagcagtgg tcacatggga cagatgaaca tgaaccccat gcccatgtct ggcatgccta
4441 tgggtcctga tcagaaatac tgctgacatc tctgcaccag gacctcttaa ggaaaccact
4501 gtacaaatga cactgcacta ggattattgg gaaggaatca ttgttccagg catccatctt
4561 ggaagaaagg accagctttg agctccatca agggtatttt aagtgatgtc atttgagcag
4621 gactggattt taagccgaag ggcaatatct acgtgttttt cccccctc
//