LOCUS AF014643 3528 bp DNA linear HUM 02-JAN-1998
DEFINITION Homo sapiens connexin46.6 (Cx46.6) gene, complete cds.
ACCESSION AF014643
VERSION AF014643.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3528)
AUTHORS Bloemker,B.K., Swaroop,A. and Kimberling,W.J.
TITLE Cloning and Molecular Characterization of Human Connexin46.6, a New
Gap Junction Gene
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3528)
AUTHORS Bloemker,B.K., Swaroop,A. and Kimberling,W.J.
TITLE Direct Submission
JOURNAL Submitted (02-JUL-1997) Genetics Dept., Boystown National Research
Hospital, 555 N 30th St., Omaha, NE 68131, USA
FEATURES Location/Qualifiers
source 1..3528
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q41-q42"
repeat_region 764..834
/note="9-22-9-22-9 bp repeat"
gene <1386..3472
/gene="Cx46.6"
mRNA <1386..3472
/gene="Cx46.6"
/product="connexin46.6"
CDS 1414..2724
/gene="Cx46.6"
/note="gap junction protein"
/codon_start=1
/product="connexin46.6"
/protein_id="AAB94511.1"
/translation="MSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIY
SDEQAKFTCNTRQPGCDNVCYDAFAPLSHVRFWVFHIVVISTPSVMYLGYAVHRLARA
SEQERRRALRRRPGPRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAE
GAGEEAEEAGAEEACTKAVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARA
AFEVAFLVGQYLLYGFEVRPFFPCSRQPCPQVVDCFVSRPTEKTVFLLVMYVVSCLCL
LLNLCEMAHLGLGSAQDAVRGRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVV
RAAERARAHDQNLANLALQALRDGAAAGDRDRDSSPCVGLPAASRGPPRAGAPASRTG
SATSAGTVGEQGRPGTHERPGAKPRAGSEKGSASSRDGKTTVWI"
regulatory 3451..3456
/regulatory_class="polyA_signal_sequence"
/gene="Cx46.6"
BASE COUNT 551 a 1082 c 1257 g 638 t
ORIGIN
1 gcatgcacgt gtacatgtgt atgcatgtgt gtgcatgggt atctgcatat gcatgtgcgt
61 gttcatgcat gtgcacgtgt gtgcatgtgt acacatgtga atctgtgggt atgtatctga
121 gtgtgtgtgc acatgtgaat gtgtgtggct ctgaggggta ctgcacagat gtgaggaagc
181 agggccactt ccccaggaac cctgactgcc ccctcttcct gccccgggtg gggaggcctc
241 agctgcataa agaggccggg agcctcacca gcgactgctg ctggtcccac acctgccgct
301 gctgcctccc aggccaggta ccgggagggg gccagaggcg gagggagcta aggggtctcc
361 tgcctcagcg acccaggagc aggtactggc cctggggcaa ccgccagcag agggtgggca
421 ggggagctgc aggagctctc cttctttgga gcacaggccc tgctgcacag ccctttcctg
481 ggcacttgcc caccttgggc ttggctggtc tgcggcatag ctgtctctga gggtcgcagg
541 tgctgagtgt ggcctcacat cactgggtct ataacctcgc tggacaccgt ccctcctgga
601 cggacgactg gcttcatcct gaccccagct agagatggtc tgggttgaga ccatggagga
661 ccaggaacct agactgggcg ggcggagccc tgggaccctg ggcacctgag aagggcagcg
721 ggaccagccg ggggctggag ggaggatgga ggattttgtg gaggtggagg gaccccgacg
781 cccctgtcca gggtgtggag ggaccccgac gcccctgtcc agggtgtgga gggaggcaca
841 tcatggcctc tgggggccga ggggctatgg ggattgtgga ctggtggcac tttggggtct
901 gggacctgat ggtggtgcac gcacgggggg ctgtgaagga ctgatggctg atggggctgc
961 tcgggcttgg gggctaggga gctggagggg ccacgaggga ttgagtggct acgcaggctg
1021 gggagaccct ttggatgctg aaactctgtg ggaccctccc caacaacctg gatgcggctg
1081 gggctgggtt ggtggccatg ggtgcactgg acactgatac caccagtccc cacacacttg
1141 agtggtgctt gcctcagtgt ccccatctgc ctcatgaagg caactcaccc acctggggcc
1201 ctgcatctgc accaccatgg gccggatcac gtgggggctt ccacttccgt ttaaggcggt
1261 aagctccacg tcattgactg tgtaagcaga gaggggccag ctgccatgca agcctggagc
1321 cccggctctg agcgccgcgg gctcctaagt gcaggcccct ggctgacccc taccccgccc
1381 cacaggaccc gcccgcccgc ccctatgacc aacatgagct ggagcttcct gacgcggctg
1441 ctggaggaga tccacaacca ctccaccttc gtgggcaagg tgtggctcac ggtgctggtg
1501 gtcttccgca tcgtgctgac ggctgtgggc ggcgaggcca tctactcgga cgagcaggcc
1561 aagttcactt gcaacacgcg gcagccaggc tgcgacaacg tctgctatga cgccttcgcg
1621 cccctgtcgc acgtgcgctt ctgggtcttc catattgtgg tcatctccac tccctcggtc
1681 atgtacctgg gctacgccgt gcaccgcctg gcccgtgcgt ctgagcagga gcggcgccgc
1741 gccctccgcc gccgcccggg gccacgccgc gcgccccgag cgcacctgcc gcccccgcac
1801 gccggctggc ctgagcccgc cgacctgggc gaggaggagc ccatgctggg cctgggcgag
1861 gaggaggagg aggaggagac gggggcagcc gagggcgccg gcgaggaagc ggaggaggca
1921 ggcgcggagg aggcgtgcac taaggcggtc ggcgctgacg gcaaggcggc agggaccccg
1981 ggcccgaccg ggcaacacga tgggcggagg cgcatccagc gggagggcct gatgcgcgtg
2041 tacgtggccc agctggtggc cagggcagct ttcgaggtgg ccttcctggt gggccagtac
2101 ctgctgtacg gcttcgaggt gcgaccgttt tttccctgca gccgccagcc ctgcccgcaa
2161 gtggtggact gcttcgtgtc gcgccctact gaaaagacgg ttttcctgct ggttatgtac
2221 gtggtcagct gcctgtgcct gctgctcaac ctctgtgaga tggcccacct gggcttgggc
2281 agcgcgcagg acgcggtgcg cggccgccgc ggccccccgg cctccgcccc cgcccccgcg
2341 ccgcggcccc cgccctgcgc cttccctgcg gcggccgctg gcttggcctg cccgcccgac
2401 tacagcctgg tggtgcgggc ggccgagcgc gctcgggcgc atgaccagaa cctggcaaac
2461 ctggccctgc aggcgctgcg cgacggggca gcggctgggg accgcgaccg ggacagttcg
2521 ccgtgcgtcg gcctccctgc ggcctcccgg gggcccccca gagcaggcgc ccccgcgtcc
2581 cggacgggca gtgctacctc tgcgggcact gtcggggagc agggccggcc cggcacccac
2641 gagcggccag gagccaagcc cagggctggc tccgagaagg gcagtgccag cagcagggac
2701 gggaagacca ccgtgtggat ctgagggcgc tggcttgcga gctgggccag ggaagaggag
2761 ggttgggggg ctccggtgga aacctgcgac cccttctcct cagccttctc cttagccggt
2821 ggcctcaggc agactctgcc cagaggggca gccaggctgc tcagggaagg ggctgaaagc
2881 ggcagaggag tgccctggct tggtcaccac tggggccaag gtggggtgga gagaggccta
2941 cgagccagaa agggccctct gctgtggtct gaaccccagg gggagtgggg cattgactcc
3001 acccctgtcc tgagctggaa taggtcctct gggatgccag ctctcccctt tgtgcttccc
3061 tgcagcaacc catggagggc ccagggtgcc tggtatgggc atcagttggt gggggtgcgg
3121 gggtgcgtgt ccccattccc tgcaacagca aatggggctc cttcttcagc cctccccttc
3181 ccagccccaa actgagacag actgggagct gggagcctgg ggtggacagg accataccct
3241 ctttgagctt ctgcgatgcc ggccttccgt tcctctggga ggcttgaagt tctgcagaga
3301 tgttgatatg ccttgcagct tggacccaat gggtggtggt cagggcctgg gggcttggcc
3361 atgctggggg aatggggctc tgggttcctg cctgtggcct gtctgtcctc ctccctaatt
3421 cagacccagc ctcaagagga aagggagtaa aataaaacta acttgtttat aaccttgtgt
3481 gtgcatgtgt atgcatgtgc acgtgtggct atgtgtgtga ctgcatgc
//